共查询到20条相似文献,搜索用时 0 毫秒
1.
Miller SB Turner JR Sherwood A Brownley KA Hinderliter AL Light KC 《International journal of behavioral medicine》1995,2(4):339-357
White offspring of hypertensives typically exhibit an elevated cardiovascular response to stress. Studies of Black offspring
of hypertensives have been fewer, with inconsistent results. This may be due, in part, to incomplete characterizations of
hemodynamic responses. This study examines cardiovascular reactivity in Black and White offspring of hypertensives with a
particular focus on vascular resistance responses. A total of 62 healthy normotensive men, 41 with a parental history of hypertension
(PH+: 21 Blacks, 20 Whites), and 21 without parental hypertension (PH-: 7 Blacks, 14 Whites) engaged in a series of laboratory
tasks. Both Black and White PH+ participants exhibited elevated diastolic blood pressure (DBP) responses, but to different
patterns of stressor tasks. Familial differences in total peripheral resistance response were also obtained for Black and
White participants in a comparison across all tasks, but were particularly evident in tasks when PH+ participants had elevated
DBP responses. These results suggest that a parental history of hypertension is an important moderator of cardiovascular,
and in particular peripheral vascular, responses to stress in Black and White individuals.
This research was supported in part by National Institutes of Health Grants HL31533 and RR00046. We thank Doris Murrell, Antonia
Vincent, Nancy Pettee, and Deborah Jansen for their technical assistance. 相似文献
2.
Eric G. Benotsch Alan J. Christensen Laura McKelvey 《Journal of behavioral medicine》1997,20(2):163-176
The present study compared ambulatory blood pressure in male and female subjects preselected for high and low hostility levels and investigated interpersonal daily stress as a possible mediational mechanism. Ambulatory blood pressure and heart rate were measured in 48 male and female students previously classified as high or low on the Cook-Medley Hostility (Ho) Scale. Subjects wore an ambulatory monitor for a working day and also completed measures of perceived social support, daily interpersonal stress, and health behavior information. Results indicated that subjects scoring high on the Ho scale had higher mean levels of ambulatory systolic blood pressure than low Ho subjects, even when controlling for traditional risk factors, such as cigarette smoking. High Ho subjects also reported greater daily interpersonal stress and less social support than low Ho subjects. Perceived interpersonal stress partially accounted for the relationship between hostility and blood pressure. Subjects high in hostility showed greater mean ambulatory systolic blood pressure levels. Consistent with the transactional model of hostility and health, the relationship between hostility and blood pressure appears to be partially accounted for by the daily experience of interpersonal stress. 相似文献
3.
This study examined the relations of one’s own total trait hostility and one’s spouse’s hostility as influences on cardiovascular
(CV) responses to couple interactions (including conflict discussions) in 45 married couples aged 24—50. Systolic blood pressure
and cardiac index (CI) reactivity to conflict discussion and recovery after conflict was greater in low hostile males if they
were interacting with high hostile wives (p < .02). Vascular resistance index (VRI) reactivity to interactions was greater
in high hostile husbands with high hostile wives (p < .05). Women showed no adverse CV effects of having a hostile spouse
when their own hostility was low. Instead, seeming to anticipate the subsequent couple interactions, wives from duos in which
both partners were high in hostility had higher baseline VRI levels and lower baseline CI compared to wives from duos in which
both were low in hostility (ps < .05), and they simply maintained these group differences with no greater CV reactivity during
the interactions. Findings suggest that CV responses before, during, and after marital discussions, particularly those characterized
by conflict, may be influenced not only by one’s own hostility but by the hostility of one’s partner as well. 相似文献
4.
Cardiovascular and neuroendocrine reactivity to acute stress are important predictors of health outcomes in non-pregnant populations. Greater magnitude and duration of physiological responses have been associated with increased risk of hypertensive disorders and diabetes, greater susceptibility to infectious illnesses, suppression of cell-mediated immunity as well as risk for depression and anxiety disorders. Stress reactivity during pregnancy has unique implications for maternal health, birth outcomes, and fetal development. However, as compared to the larger literature, our understanding of the predictors and consequences of exaggerated stress reactivity in pregnancy is limited. This paper reviews the current state of this literature with an emphasis on gaps in knowledge and future directions. 相似文献
5.
This study examined whether relationships between anger expression, hostility, social evaluative anxiety, and a presumed mechanism for coronary heart disease development, cardiovascular reactivity (CVR) to stress, are moderated by stress situation and gender and whether such relationships are attenuated by inadequate assessments. Subjects (47 men, 47 women) were assigned randomly to either a Harassment or a Social Evaluation condition, under which they performed a reaction time task. SBP, DBP, and HR measures were recorded during baseline and task. Multiple regression analyses indicated that expressed anger was related to CVR only among men in the Harassment condition; that hostile men who express anger showed the most CVR across situations, and that the traits assessed here did not predict CVR among women. Results suggest that assessments of coronary-risk and interventions to reduce risk may need to take into account attitudes, styles of emotional expression, environmental factors, and gender.This research was supported in part by an NIMH predoctoral fellowship (F31MH09836) awarded to John W. Burns and by a grant from the American Heart Association (89-01-3G) awarded to Edward S. Katkin. 相似文献
6.
Jorge Jurez Irma del Rio-Portilla María Corsi-Cabrera 《Developmental psychobiology》1998,32(2):121-129
From Days 14 to 19, pregnant Wistar rats were treated with either 2 mg of testosterone propionate (TP) or vehicle. Thirty-, 60-, and 90-day-old offspring were tested individually during 15 min daily on 4 days with a stimulus litter, and pup-oriented and non-pup-oriented behaviors were recorded. Sex differences in pup-oriented behaviors observed in oil groups were eliminated by TP treatment, which affected mainly females. Additionally, TP treatment increased the frequency of self-grooming and decreased the time spent near the pups and the frequency of sniffing and pawing only at 90 days of age. Hiding behavior only occurred at 30 days of age, while pawing near the pups and lying-down behavior was observed mainly in adults. Results show that sex differences in behavior are present before subjects become sensitized to show evident maternal behavior, and suggest that prenatal androgens play an important role in the manifestation of these sex differences and that its effects depend on developmental factors. © 1998 John Wiley & Sons, Inc. Dev Psychobiol 32: 121–129, 1998 相似文献
7.
Department of Biochemistry, Biophysics, and Physiology, N. G. Chernishevskii Saratov University. (Presented by Academician of the Academy of Medical Sciences of the USSR K. V. Sudakov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 113, No. 1, pp. 26–28, January, 1992. 相似文献
8.
Baron KG Smith TW Butner J Nealey-Moore J Hawkins MW Uchino BN 《Journal of behavioral medicine》2007,30(1):1-10
Hostility may contribute to risk for disease through psychosocial vulnerability, including the erosion of the quality of close
relationships. This study examined hostility, anger, concurrent ratings of the relationship, and change in marital adjustment
over 18 months in 122 married couples. Wives’ and husbands’ hostility and anger were related to concurrent ratings of marital
adjustment and conflict. In prospective analyses, wives’ but not husbands’ hostility and anger were related to change in marital
adjustment. In hierarchical regression and SEM models wives’ anger was a unique predictor of both wives’ and husbands’ change
in marital adjustment. The association between wives’ anger and change in husbands’ marital satisfaction was mediated by husbands’
ratings of conflict in the marriage. These results support the role of hostility and anger in the development of psychosocial
vulnerability, but also suggest an asymmetry in the effects of wives’ and husbands’ trait anger and hostility on marital adjustment. 相似文献
9.
We examined the association between prenatal exposure to cigarettes and adrenocortical responses to stress in 7-month-old infants. Cortisol levels were assessed twice prior to and twice following affect-eliciting procedures in 111 (59 exposed and 52 nonexposed) infants. Cortisol reactivity was defined as the difference between the peak poststressor cortisol level and the pretask cortisol level. Higher values indicated higher cortisol reactivity. Exposed infants had higher peak cortisol reactivity than nonexposed infants. There were no differences in pretask cortisol levels. Maternal hostility mediated the association between cigarette exposure and peak cortisol reactivity. Furthermore, infant gender moderated this association such that exposed boys had significantly higher peak cortisol reactivity than nonexposed infants or exposed girls. These findings provide additional evidence that prenatal cigarette exposure is associated with dysregulation during infancy and that early adverse, nonsocial experiences may have relatively long-lasting effects on cortisol reactivity in infants. 相似文献
10.
目的研究不同支架参数对血管壁面再狭窄的影响,为设计支架形式提供参考和依据。方法根据支柱的螺纹节距、支柱数目、支柱线径、支架突入流域深度、支柱截面形状对支架进行分组,利用三维计算流体动力学(computational fluid dynamics,CFD)模拟方法研究各个参数的不同设置对血管壁面剪切应力分布的影响。结果支架的支柱线径对壁面剪切应力影响最为显著,并且支架参数中节距变短、支柱数目增加、线径变宽、突入流域深度增加会导致壁面低剪切应力区域面积增加;相对于三角形与正方形截面形状,圆形截面支架导致的低剪切应力区域面积更少。结论支架在设计过程中应采用圆形截面,而且应尽可能缩小线径,增长节距,减少支柱数目,减小突入流域深度。 相似文献
11.
12.
Nelson C Franks S Brose A Raven P Williamson J Shi X McGill J Harrell E 《Journal of behavioral medicine》2005,28(3):213-221
Autonomic activation in response to controllable versus noncontrollable stress, anger imagery induction, and relaxation imagery was studied among 80 participants between the ages of 18 and 34 years. Participants differed in level of trait hostility and family history of cardiovascular disease. Results were obtained through power spectral analyses of electrocardiograph R-R intervals, which produced an index of autonomic nervous system activation. For both male and female populations, parasympathetic regulation was diminished during anger induction for individuals with high levels of trait hostility and having a family history of cardiovascular disease. Similar results were obtained for women during the uncontrolled stress condition. Based on family history of cardiovascular disease and trait hostility, men responded differentially to relaxation imagery induction, whereas no differences were found among females. 相似文献
13.
Semenova MA Klimova OA Anishchenko TG 《Bulletin of experimental biology and medicine》2006,141(3):299-301
Castration of males and females reduces the sensitivity of cardiac chronotropic function to atropine and potentiates the vascular
component in the reaction to atropine in females (during stress) and males (at rest and during stress). Our results show that
estrogens and androgens increase the sensitivity of the cardiovascular system to cholinergic influences at rest and during
stress.
__________
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 141, No. 3, pp. 270–272, March, 2006 相似文献
14.
Anishchenko TG Glushkovskaya-Semyachkina OV Berdnikova VA Sindyakova TA 《Bulletin of experimental biology and medicine》2007,143(2):178-181
In healthy females the chronotropic effects of stress are more pronounced, while the hypertensive effects are weakened compared
to males. Hemodynamic parameters in females returned to normal more rapidly than in males. Renovascular hypertension in males
is more pronounced than in females and is associated with increased cardiovascular stress reactivity (in females it is associated
with decreased cardiovascular stress reactivity), which increase the risk of cardiovascular complications in males.
__________
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 2, pp. 136–139, February, 2007 相似文献
15.
Pollitt RA Daniel M Kaufman JS Lynch JW Salonen JT Kaplan GA 《Journal of behavioral medicine》2005,28(1):53-64
Hopelessness and hostility are linked to progression of carotid atherosclerosis (PCA). The purpose of this study was to replicate such relations and to evaluate the role of biological pathways involving hyperactivation of the sympathetic nervous system (SNS) and the hypothalamic–pituitary–adrenocortical (HPA) axis. PCA was evaluated by 4-year change in three ultrasound measures of intima-media thickness (IMT) in 1027 men aged 42–60 years at baseline. Effect modification and mediation of relationships between psychosocial factors and PCA were examined for the measures systolic blood pressure (SBP), fibrinogen, and waist-to-hip ratio (WHR), levels of which are indicative of activity along these pathways. Hopelessness and hostility were associated with PCA. Fibrinogen mediated to a moderate extent the association between hopelessness and PCA. SBP significantly modified the relation between hostility and PCA in participants of moderate hostility. The above biological pathways are implicated in the mechanisms connecting hopelessness, hostility, and PCA. 相似文献
16.
17.
Dean G. Cruess Michael H. Antoni Mahendra Kumar Bonnie McGregor Susan Alferi Amy E. Boyers Charles S. Carver Kristin Kilbourn 《International journal of behavioral medicine》2001,8(3):194-207
We examined the effects of a10-week, group-based cognitive-behavioral stressman-agement (CBSM) intervention on serum testosterone
levels in women with Stage 1or 2 breast cancer. At 4 to 8 weeks postsurgery, participants were randomized to CBSM (n = 24) or to a wait-list control group (n = 10). Free and total testosterone was assessed via radioimmunoassay before and after the study period. The participants
also completed a questionnaire assessing the degree to which living with breast cancer had led to social and emotional benefits
in their life. We observed significant decreases in testosterone levels in the CBSM group and no change in the controls. Decreasesintes-tosterone
were related to increases in positive contributions. These findings suggest that a short-term psychological intervention can
help modulate androgen functioning, and these changes are related to enhanced benefit finding observed among women with breast
cancer participating in CBSM. 相似文献
18.
Hostility,coronary heart disease,and total mortality: A 33-year follow-up study of university students 总被引:2,自引:0,他引:2
Marsha D. Hearn David M. Murray Russell V. Luepker 《Journal of behavioral medicine》1989,12(2):105-121
Hostility as measured by the Cook-Medley Hostility (HO) Scale on the Minnesota Multiphasic Personality Inventory has been suggested as a risk factor for coronary heart disease (CHD) and total mortality. This study tested the HO-CHD hypothesis in a sample of 1399 men who entered the University of Minnesota in 1953 and, as part of freshman orientation, completed the MMPI. Current health status was ascertained for 94% of the sample through telephone interviews 33 years later. Higher HO scores did not predict CHD mortality, CHD morbidity, or total mortality either before or after adjustment for baseline risk factors. Among the plausible explanations for these results are that (1) hostility is not a risk factor in all populations, (2) the HO scale at age 19 does not assess a stable psychological characteristic, or (3) the HO scale is not an adequate measure of hostility.This research was supported by a University of Minnesota, School of Public Health, Biomedical Research Support Grant (2S07-RR05448) and the National Heart, Lung, and Blood Institute (2T32-HL07328). 相似文献
19.
20.
Miller GE Freedland KE Carney RM Stetler CA Banks WA 《Journal of behavioral medicine》2003,26(6):501-515
Although the prognostic significance of depression and hostility has been established, little is known about how they operate together to influence disease processes. This study explored the independent and interactive relationships between these constructs and the expression of inflammatory markers implicated in the pathogenesis of coronary heart disease. One hundred adults completed measures of cynical hostility and depressive symptoms, and had blood drawn to assess serum levels of interleukin-1, interleukin-6, and tumor necrosis factor-. Depression was directly related to inflammatory markers, but hostility was not. A significant interaction between hostility and depression emerged. Among participants scoring low in depressive symptoms, hostility was positively associated with interleukin-6 and tumor necrosis factor- concentrations. Hostility's association with these inflammatory markers was much weaker among participants with moderate depressive symptoms, however, and virtually nil among participants with severe depressive symptoms. Neither depression nor hostility was associated with interleukin-1 concentrations. These findings highlight the importance of considering both the independent and interactive relationships among psychosocial characteristics involved in disease. 相似文献