新冠肺炎疫情下口腔科护士继续教育需求调查

探讨新冠肺炎疫情下口腔科护士的继续教育需求,为护理管理者提供参考.研究表明,新冠肺炎疫情影响下,口腔科护士最大的继续教育需求是感染预防和控制.护理管理者应根据护士的需求制定培训计划,重视继续教育内容的实用性,做到理论联系实际.     

新冠肺炎康复期患者死亡焦虑与生命意义感现状调查与分析

目的：调查新冠肺炎康复期患者死亡焦虑与生命意义感现状,分析其相关影响因素,为患者心理状况的改善提供依据。方法：采用生命意义感量表、死亡焦虑量表对样本医院收治的76例新冠肺炎康复患者进行问卷调查。采用t检验、单因素方差分析、Person相关分析进行统计学检验,检验水准取α=0.05 （双侧）。结果：新冠肺炎康复期患者死亡焦虑得分为（44.70±8.93）分,生命意义感得分为（47.57±14.02）分;隔离期间每天使用手机的时间是影响其死亡焦虑的重要因素,死亡焦虑得分与隔离时间呈正相关,隔离期间每天运动的时间是影响其生命意义感的重要因素。结论：新冠肺炎康复期患者普遍存在高死亡焦虑,与隔离期间每天手机使用时长与隔离时长密切相关。此外,新冠肺炎康复期患者的生命意义感处于中等水平,运动是新冠肺炎康复期患者生命意义感的影响因素。护理人员对新冠肺炎康复期患者的心理护理不仅可以从正确认识新冠病毒、正确认识死亡等方面转移注意力,也可以借助运动等方式,调节患者情绪。     

“平疫结合”护理策略在“后新冠肺炎时期”神经介入治疗患者围手术期的应用研究

目的〖KG*2〗探讨“后新冠肺炎时期”对神经介入治疗患者围手术期开展“平疫结合”的护理策略,为临床护理提供可参考依据。 〖HTH〗方法〖KG*2〗选择疫情期间神经介入治疗患者96例为试验组,按照“平疫结合”护理策略采取有针对性的护理干预措施,并对医护人员的个人防护加以规范。另选择非疫情期间神经介入治疗患者362例为对照组,采用常规护理。比较2组穿刺点并发症、护理不良事件发生率和患者满意度评分。 〖HTH〗结果〖KG*2〗试验组均完成“新冠肺炎”入院筛查,无疑似病例及确诊病例,住院期间无新发“新冠肺炎”确诊病例及疑似病例。医护人员无确诊感染病例及疑似病例。2组穿刺点并发症、护理不良事件发生率和患者满意度评分差异均无统计学意义（P＞0.05）。 〖HTH〗结论〖KG*2〗“后新冠肺炎时期”神经介入治疗患者围手术期采用“平疫结合”护理策略,可以预防不良事件发生,保障医院正常有序开展医疗护理工作。     

流程化护理在新冠疫情期间肿瘤患者PET/CT检查中的应用

目的 探讨流程化护理在新冠疫情期间肿瘤患者正电子发射计算机断层成像(PET/CT)检查中的应用效果。方法 根据国家卫生健康委员会颁布的一系列新型冠状病毒肺炎(简称“新冠肺炎”)诊疗方案、防护措施和指南,结合PET/CT检查的特点,总结新冠肺炎后疫情期间PET/CT检查的护理工作流程与辐射防护要点。结果 在严格遵守新冠肺炎后疫情期间核医学PET/CT显像护理防控措施,进一步优化了核医学PET/CT检查各个环节的防控管理,确保了医患之间的“零感染”。结论 严格执行新冠肺炎后疫情期间PET/CT显像流程化护理防控措施,可以有效预防医患之间交叉感染,并保证PET/CT检查的顺利完成和医疗质量。     

新型冠状病毒肺炎疫情期间某医院干部病房的防控措施

目的 探讨干部病房在新型冠状病毒肺炎(简称新冠肺炎)疫情期间的防控措施.方法 严格落实医院针对防控新冠肺炎的措施,结合科室医疗护理工作的实际,制定以人员管理、病区管理、消毒卫生管理为核心的应对措施.结果 科室患者及工作人员均未感染新冠肺炎,医疗护理工作正常运行.结论 落实有效的疫情防控措施,提高病区的疫情防控能力.     

组胺受体拮抗剂在新型冠状病毒肺炎治疗中的应用及作用机制研究进展

新冠肺炎已造成全球范围内的大流行,迫切需要找到限制感染和改善症状的治疗方法。由于新药开发过程耗时,老药新用可能是解决现状的更好出路。有研究通过同源建模及基于靶标的虚拟配体筛选,提示组胺受体拮抗剂对治疗新冠肺炎具有广阔前景。继有临床分析显示H2受体拮抗剂法莫替丁对于改善新冠肺炎患者的症状和预后是积极有效后,围绕组胺拮受体抗剂在新冠肺炎治疗中的临床和基础研究也越来越多,并显现出比较可靠的应用前景。本文对组胺受体拮抗剂及其联合用药在新冠肺炎患者中的治疗效果及相关作用机制,以及组胺受体拮抗剂在新冠肺炎治疗中的前景作一综述。     

中西医结合治疗新型冠状病毒肺炎高度疑似病例1例及核酸检测分析

文章总结1例采用中西医结合治疗新型冠状病毒肺炎（简称新冠肺炎）高度疑似病例的诊治经过,该患者流行病学史、临床症状、影像学表现及实验室检查与新冠肺炎高度相符,但5次核酸检测阴性,对其核酸检测结果进行分析,以期对目前新冠肺炎的防护、识别及治疗提供帮助。     

预检分诊护士抗击新型冠状病毒肺炎认知体验的质性研究

〔目的〕了解预检分诊护士在新型冠状病毒肺炎(新冠肺炎)疫情中的心理状态及对科室相关配套设施的需求,为护理人文关怀提供参考依据.〔方法〕采用目的抽样方法,选取2020年1月20日至8月20日在河南省肿瘤医院预检分诊处工作的11名护士为研究对象,分别对每位护士进行半结构访谈,访问内容包括个人基本情况、对新冠肺炎的认知情况、...     

从“膜原”论治新型冠状病毒肺炎

新型冠状病毒肺炎(COVID-19,简称新冠肺炎)是一种具有强烈传染性的呼吸系统疾病。笔者跟随团队亲临疫情前线,运用中药诊治新冠肺炎,总结新冠肺炎患者临床病症,认为此病起病急,变症快,与中医"疫病、瘟疫、温病"的发病、传变极其相似,从"膜原"角度论治新冠肺炎临床疗效好。本文总结从"膜原"论治新冠肺炎的诊治思维,以期为中医防治新冠肺炎提供借鉴。     

从伏邪理论探讨新型冠状病毒肺炎的发病特点

目的 探索新型冠状病毒肺炎(简称“新冠肺炎”)的发病特点、病因及病机演变,为疫情防控与治疗提供参考。方法 (1)数据统计：依据2020年1月—2022年6月明确记录患者入院时寒热情况的相关文献15篇,统计新冠肺炎患者入院时寒热类型对应的病例数及频率。依据2022年7月前新冠肺炎变异株临床诊疗文献12篇,统计新冠肺炎不同变异株的病因属性。(2)文献研究：查阅新冠肺炎相关理论探讨文献,采用文献研究法从新冠肺炎临床表现、治疗原则、治法方药等方面讨论新冠肺炎的发病特点及病机演变。结果 新冠病毒及其变异株主要病因属性为湿疫毒。新冠肺炎早期可见恶寒、发热,以低中热为主,部分表现为往来寒热、身热不扬等。一些新冠肺炎无症状感染者已有肺部炎症表现。肺部影像学呈现多发小斑片影及肺间质改变,并有外周血白细胞计数降低、淋巴细胞计数降低等实验室指标改变。新冠肺炎中期临床表现以肺系病变和脾胃病变为主,重症期可见呼吸困难、神志异常,严重者可发展为急性呼吸窘迫综合征、急性肾损伤、肝功能损害等。此外,临床部分痊愈者存在核酸检测复阳现象。临证中应用解表清里、化湿解毒的治法多有较好疗效。结论 新冠肺炎的发病过程为湿疫毒从口...     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.     

Possible Spread of adenovirus type 3 from poultry to humans ：indirect evidence from an outbreak in China

Objective:To explore the epidemiology and etiology for an outbreak of acute respiratory tract infection that occurred in one county of Jiangsu Province, China 2004. Methods: Only cases meeting the case definition were included in the study. We reviewed the medical records of the cases who were admitted to the local hospitals, interviewed cases by a standard questionnaire, and then described the epidemiotogic features and analyzed risk factors by means of a case-control study. We collected pharyngeal swab specimens and sent them to different laboratories for isolation and culture. The laboratory used different detection methods such as DIP, PCR, electron microscope examination and microneutralization assay, to identify and then type the positive specimens. Results:A total of 871 cases were reported during the period from April 18 to July 4,2004. The distribution of onset times presented two peaks, one in late May and another in middle June. The epidemic occurred mainly in the elementary and junior high schools in ten townships of one county, and the mean age of the cases was 12 years (range 7 months to 18 years). The course of the disease was acute, and was characterized by fever accompanied with sore throat and tonsillitis. The WBC count of cases was normal or elevated. The mean duration of illness was 5 days (range 2 to 12 days). No fatalities from illness were reported. A case-control study indicated that the possible risk factors were close contact with a case and/or poultry before onset and sharing of towels among members of the family. The typical CPE was observed through inoculating pharyngeal swab specimens into the HEP-2 cell cultures in different laboratories. An infection of adenovirus type 3 was verified by detecting positive specimens in different methods. Conclusion:This investigation demonstrated that the acute respiratory infection in cases was caused by adenovirus type 3. Cases occurred in over 70 schools in ten townships in 2004, and the route of transmission was possibly close contact with cases or droplet transmission.