共查询到20条相似文献，搜索用时 15 毫秒
1.
Waleed M. Hetta Mostafa Mahmoud Abdelkawi Mohammed H. Abdelbary Marihan A. Nasr 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(4):1049-1055
Purpose
To estimate the accuracy of 18FDG PET/CT in detection of recurrent cancer ovary and to describe the localization of metastases for restaging.Materials and methods
44 female patients with suspicion of ovarian cancer recurrence underwent a PET/CT scan from September 2013 to August 2015.Results
CA-125 levels were elevated in 36 patients, 25 patients presented with alterations on imaging and 18 patients had clinical suspicion of recurrence. Imaging examinations were normal in 10/36 patients with elevated CA-125. 18FDG PET/CT scan was positive in 39/44 patients, and it was negative in 5/44 patients, 4/5 patients continued to be disease free all over the follow-up (true negative), while PET-CT missed recurrence in 1/5 patient (false negative). 1/39 patient was false positive. Sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of integrated PET/CT were calculated to be 91%, 76%, 96%, 50% and 87%.Conclusion
18FDG PET/CT is an accurate modality for detection of recurrence of ovarian cancer. The accuracy of PET–CT in precise localization of suspicious FDG uptake can lead to proper assessment of disease recurrence, thus allow for restaging of the disease and subsequently optimizing treatment plan for these patients. 相似文献2.
Susan Adil Ali Maged Abd Elgalil Hamed 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(3):671-676
Purpose
to assess the efficacy of FDG PET/CT in detecting unexpected additional primary malignant neoplasms in patients being evaluated by PET/CT for known malignancies compared to conventional staging work-up (CSW).Patients and methods
Of 1889 patients referred for whole-body FDG PET/CT in the period from February 2015 to May 2016, only 273 were included in this prospective study. Patients included are those with histopathologicaly proven primary malignancy and sent for initial tumor staging before treatment within 1 month of CSW that was performed for the patients according to the site and cell type of the primary tumor. Histopathologic examination was performed for lesions indicating additional primary cancer detected by either PET/CT or CSW.Results
In 13 out of 273 patients included in the study (4.76%) only were proved to have additional primary cancer, the PPV of PET/CT for detecting an additional primary cancer was 56.5%. Also, it showed high sensitivity of 89.2%, which was significantly higher than 23% from the CSW (P < 0.005).Conclusion
PET/CT is more accurate than CSW for detecting additional primary cancer with a higher sensitivity and positive predictive value, which consequently affect further management. 相似文献3.
Ekhlas Abdelmonem Ibrahem Nasr Shaban 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(4):1057-1063
Purpose
The aim of this study is to clarify the role of 18-F-FDG PET/CT over CT alone in the detection of primary, recurrent and metastatic disease in renal cancers patients.Patients and methods
In this study; 18-F-PET/CT scans were performed for 25 patients (19 males and 6 females) with renal cancer. A patient-based analysis was performed in a dedicated manner to pick up lesions on CT, PET and PET/CT fused images. Statistical analysis was calculated. A final diagnosis of disease extent was affirmed by clinical, radiologic workup and histopathological correlation.Results
PET/CT has 100% sensitivity, 93% specificity, 100% PPV, 91% NPV and 96% accuracy; compared to 100% sensitivity and 70% specificity, 83% PPV, 100% NPV and 88% accuracy for CT in diagnosis of primary, recurrent and metastatic disease in renal cancer.Conclusion
Incorporated 18-F FDG PET/CT is a very versatile and accurate imaging technique for renal cancers. It significantly improves the accuracy and predictive values over CT alone for detection of primary, recurrent and metastatic disease in renal cancer thus change the treatment decision. 相似文献4.
Youssriah Yahia Sabri Marian Fayek Farid Kolta Mostafa Ahmed Khairy 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(3):569-580
Background
Diffusion-weighted imaging is a fundamental tool integrated in MR protocols useful in differentiating benign from malignant mediastinal masses, assessing mediastinal lymphadenopathy and investigating central bronchogenic carcinoma. This method is an excellent alternative to CT or PET/CT in the investigation of mediastinal masses. Current applications of diffusion MRI in malignancies include monitoring the treatment response and detecting recurrent cancer.Aim of the work
This study aims to assess the value of using MRI diffusion in differentiating benign and malignant mediastinal masses, differentiating central masses from post obstructive collapse and differentiating lymphoma versus sarcoidosis.Patients and methods
This study included 30 patients; 16 males and 14 females in the period from June 2013 to July 2014. The mean age was 49.3 ± 16.85 (range: 22–82 years).Cases were referred for MRI assessment and were approved by the ethical committee in our department.The complaints varied between dyspnea, chest pain, cough, hemoptysis, fatigue and loss of weight. A superconducting 1.5 T MRI machine with a four-channel body phased-array coil was used for the examination. Biopsy and histopathological assessment was done after that.Results
MRI examination with diffusion imaging was able to differentiate between benign and malignant mediastinal and hilar lesion confirmed by the biopsy and histopathology.Conclusion
MRI with diffusion weighted images can detect and stage lung cancer, differentiate benign from malignant mediastinal masses and differentiate lymphoma from sarcoidosis in mediastinal/hilar lymphadenopathy. 相似文献5.
Ahmed R. Mohammed Ahmed Tohamy Ahmed Tarek H. Khalil Huda Fathy Refaie 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(3):707-716
Purpose
The study aims to compare the accuracy of washout and perfusion CT techniques in diagnosis of adrenal tumors.Patients and methods
A prospective study included 38 patients with incidentally detected adrenal masses on conventional abdominal CT studies performed for unrelated reasons were subjected to full medical history, physical examinations, serum creatinine assessment, dynamic perfusion CT using 64 MDCT scanner with Absolute washout (APW), Relative washout (RPW) assessment and CT perfusion parameters calculation [perfusion, Peak enhancement intensity (PEI), Time to peak (TTP) & Blood volume (BV)]. Time density curves (TDCs) for all adrenal masses were done. The gold standard was either follow up or histopathological examination after fine needle biopsy or surgical resection.Results
Washout CT differentiated between adenomas and non-adenomas using APW (≥55%) with sensitivity 73.3%, specificity 90% and accuracy 82.8%, and using RPW (≥36%) with sensitivity 53.3%, specificity 85% and accuracy 81.8%. Perfusion CT differentiated between adenomas and nonadenomas using BV (≥15 ml/100 g) with sensitivity 80%, specificity 75% and accuracy 77.1%. TDC curves of adenomas show slow-rise platform pattern.Conclusion
Perfusion CT can distinguish between adrenal adenomas and non-adenomas using the BV, however washout CT was more accurate than perfusion CT in characterization of adrenal masses using the APW and RPW. 相似文献6.
Haney Heneidy Waled Yosef Sheirin Badr 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(4):779-783
Objective
The aim of this study was to assess the ability of CT to predict the pathological nature of pancreatic cystic lesions if it is benign, malignant or premalignant.Methods
This is a retrospective study from the database of our hospital EMR (electronic medical records) for pancreatic lesions from patients who proven to be of pathological cystic nature. The diagnosis and characterization of pancreatic cysts were done by multislice 32 CT examination. We reviewed the data from the radiology, surgery and pathology departments from the period of November 2012 until January 2015. We compared between operative and pathological data and findings of MDCT using chi square test.Results
We reviewed the data from the radiology, surgery and pathology departments from the period of November 2012 until January 2015. The study was done on 66 patients. Our results showed that CT features for benign cystic lesions are lobulated shape and a thin wall (≤1?mm) while the round or oval shape or a complex cystic shape with tubular cyst and a thick wall (>1?mm) are more frequently seen in pancreatic premalignant and malignant macrocytic lesions.Conclusion
CT with thin section images allows adequate morphological characterization of macrocytic pancreatic masses that could predict its pathological nature if benign or malignant. 相似文献7.
Wessam Abdelrahman Elzayat Mona El-Kalioubie Manar Magdy Abdel-Naby Raafat Ragaie Abdel-Malek 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(4):1159-1169
Objectives
To evaluate the diagnostic accuracy of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) in characterization of inconclusive ovarian tumors, with histologic findings as the reference standard.Patients & methods
DCE-MRI was done in 30 patients with 32 complex ovarian masses, prior to surgical excision. We analyzed the following kinetic parameters: enhancement amplitude (EA) in the form of MRE%, time to peak in the form of T max and maximal slope (MS) and correlated them with histopathology.Results
DCE-MRI showed higher overall accuracy (96%) and specificity (100%) than conventional MRI. Malignant masses showed higher MRE% than benign (p?=?.004) or borderline masses (p?=?.036). A shorter T max was found in malignant compared to benign (p?=?.0002) and borderline (p?=?.049) masses. MS was best at discrimination between benign, borderline and malignant tumors. Finally, Type III curve showed 100% specificity for invasive malignant tumors.Conclusion
DCE-MRI sequence is a helpful adjunct to conventional MRI for discrimination of inconclusive ovarian masses into benign, borderline and invasive malignant tumors. 相似文献8.
Mai E.M. Khamis Ahmed M. Alaa El-deen Ahmad Abdel Azim Ismail 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(4):1149-1157
Objective
To detect the diagnostic efficiency of sono elastographic strain ratio in discriminating malignant from benign solid breast masses and compare it with the sono elastographic elasticity score method.Patients and methods
This study included 120 histopathologically diagnosed solid breast masses from 120 females (mean age 38.2?years). Elastography score and strain ratio (SR) were performed for each mass. Receiver operating characteristic (ROC) curve was plotted for both methods.Results
The benign lesions had significant lower SR (mean 2.12?±?1.72) than that of malignant lesions (mean 6.91?±?3.96). The AUC from ROC curve was 0.98 for elasticity score and 0.99 for SR. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of the elasticity score in the diagnosis of solid breast masses were 100%, 88%, 83.3%, 100% and 92.5% respectively, and of the strain ratio were 93.3%, 97.3%, 95.5%, 96.1% and 95.8% respectively (when cutoff value 3.77 was used). There is no statistically significant difference found between both methods.Conclusion
SR has high diagnostic performance in differentiating malignant from benign solid breast masses, however there is no statistically significant difference between SR and elasticity score. 相似文献9.
Tamer W. Kassem 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(2):537-545
Objective
The aim of this study was to compare the diagnostic performance of positron emission tomography/computed tomography (PET/CT) scan and CT scan in follow up of proven gynecological malignancies omental deposits in first setting follow up after treatment.Patients and methods
60 female patients having proven omental deposits from gynecological malignancies underwent PET/CT examination following a preset protocol as baseline study. 34 cases of them had a second PET/CT examination following same protocol after 5–11 months considered as first setting follow up study aiming to assess therapeutic response.Results
Out of 34 cases 2 cases (6%) showed only newly developed lesions, 8 cases (23.5%) showed progression, 8 cases (23.5%) showed mixed response and 16 cases (47%) showed regression or complete resolution. In first setting follow up examination 18F-FDG PET/CT showed 31 TP, 2 TN and 1 FN cases while CT showed 29 TP, 2 TN, 2 FN and 1 FP cases. 18F-FDG PET/CT vs. CT revealed sensitivity, specificity and accuracy of 96.88% vs. 93.55%, 100% vs. 66.67% and 97.06% vs. 91.18% respectively.Conclusion
18F-FDG PET/CT is more accurate than CT in assessment of therapeutic response of proven gynecological malignancies omental deposits in first setting follow up. 相似文献10.
Hala Yehia Yousef Haitham A. Dawood Nesreen Mohey 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(4):927-930
Aim of the work
To evaluate the role of diffusion weighted imaging (DWI) in the planning for CT guided biopsy of lung and mediastinal lesions.Subjects and methods
This cross sectional study included 23 patients with mean age was 42.7?years came with clinical and imaging suspicion of chest malignancy, referred for CT guided transthoracic biopsy. DWI and apparent diffusion coefficient (ADC) were evaluated for all patients to choose the area of maximum restriction.Results
The study showed that with DWI guidance; all the biopsy specimens were diagnostic and provide adequate material for analysis.Conclusion
DWI and measurement of ADC value has a very helpful role in the pre-procedural planning of transthoracic biopsies. 相似文献11.
Adel Ali Ramadan Mohamed Samir Shaaban Alaa Magdy El-Sayed 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(4):1097-1104
Background
Urinary tract injuries occur in 3–10% of abdominal trauma. Early recognition and diagnosis of ruptured bladder is essential to lower this mortality rate. CT is the method of choice for the evaluation of patients with blunt or penetrating abdominal and/or pelvic trauma. Imaging in patients with suspected bladder injury with CT cystography may be performed using either an intravenous or retrograde technique.Aim of work
The aim was to evaluate the role of CT in diagnosing traumatic urinary bladder injuries.Materials and methods
The study was carried out on 32 patients with suspected traumatic urinary bladder injury. All patients were subjected to contrast-enhanced CT study and classified according to Sandler et al. classification of urinary bladder injuries.Results
All patients were classified according to the type of the encountered urinary bladder trauma. Type I injury was diagnosed in 3.1% of patients, type II in 18.8%, type III in 3.1%, type IVa in 12.5%, type IVb in 43.7% and type V in 18.8%. 21.8% of patients were managed conservatively, while 78.2% of patients underwent surgical repair.Conclusion
CECT well demonstrated traumatic urinary bladder injuries. 相似文献12.
Mohamed Houseni Amr Osama Dalia Ibrahim Mohamed Shahinda Salem 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(1):67-74
Purpose
To assess the value of contrast enhanced CT (ceCT) when added to positron emission tomography combined with the standard low-dose non-contrast CT (PET/CT) protocols for staging patients with malignant pleural mesothelioma (MPM).Methods
Retrospective analysis of 47 patients with pathologically proved MPM. All patients underwent PET/CT with low dose CT followed by ceCT. PET/CT and ce-CT were evaluated separately then in combination. All the results were validated either by histopathology and/or clinical-radiological follow-up. Staging was performed based on TNM system.Results
For T-stage, the sensitivities for PET/CT, ceCT and combined PET/CT-ceCT were 89.1%, 86.9%, and 97.5%, respectively, p = 0.04. Regarding nodal stage, the sensitivity, specificity and accuracy for PET/CT were 88.5%, 90.5%, and 89.4%; for ceCT 73.1%, 95.2% and 82.9%; and for PET/CT-ceCT 96.2%, 95.2% and 95.7%, respectively. PET/CT-ceCT significantly associated with the sensitivity, p = 0.05. Considering the metastatic disease, the sensitivity, specificity and accuracy for PET/CT were 81.3%, 96.8%, and 91.5%; for ceCT 56.3%, 90.3% and 78.7%; and for PET/CT-ceCT 93.8%, 96.8% and 95.7%, respectively. PET/CT-ceCT significantly improved the sensitivity (p = 0.03) and accuracy (p = 0.02). Furthermore, combined PET/CT-ceCT significantly identified patients not suitable for surgery.Conclusion
The addition of ceCT to PET/CT protocol has significantly contributed to the staging of MPM. 相似文献13.
Ahmed Elsammak 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(4):1073-1081
Objectives
To assess the clinical utility of PET-CT in assessment of thoracic involvement in lymphoma patients prior to, during and after finishing treatment and comparing it to contrast enhanced CT (CECT).Patients and methods
PET-CT was performed for 30 patients with lymphoma. Thoracic nodal and extranodal involvement was assessed and compared to contrast enhanced CT.Results
Comparison of CECT and PET-CT in staging and assessment of treatment response reveals significant statistical difference (P?=?.0001 & .04 respectively). CECT shows sensitivity?=?83.3% and specificity?=?75% in evaluation of patients after finishing chemotherapy.Conclusion
PET-CT plays an important role in staging, detection of response to treatment and restaging of lymphoma after finishing chemotherapy. 相似文献14.
Mennatallah Hatem Shalaby Shady Samir Ahmed Deif 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(3):639-643
Objective
To compare the accuracy of 2D and 3D CT measurements of femoral anteversion angle, in pediatric patients with developmental hip dysplasia.Materials and methods
Twenty patients (20 hips) with unilateral non syndromic DDH were studies. CT scans were performed using a 16 slice CT scanner to measure the femoral anteversion angle (FAVA) using 2D & 3D techniques. Findings were correlated with the intra operative measurements.Results
There was a significant difference between 2D & 3D methods. Results of clinical assessment were comparable to results of 3D CT assessment which range from 30 to 50° with a mean of 37.5°. Mean percent difference between 3D and intra operative measurement of FAVA was significantly lower than the corresponding value between 2D and intraoperative measurement of FAVA.Conclusion
3D is more accurate than 2D in measuring the degree of FAVA in DDH patients. It is easily applied and rapid and doesn't require sophisticated software. 相似文献15.
Tamer W. Kassem 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(3):621-626
Objective
The goal of this study was to highlight the role of follow up CT angiography examination in detection and classification of endoleaks and therefore deciding management plans after endovascular abdominal aortic aneurysm repair (EVAR).Patients and Methods
During one year duration 37 patients who have been operated were examined 1 and 6 months after EVAR as routine follow up. The images obtained were interpreted and reconstructed using dedicated software and work stations.Results
Out of 37 cases, 14 cases (37.8%) had positive endoleaks and 23 cases (62.2%) were free. Type I endoleak was diagnosed in 4 cases (10.8%) and type II endoleaks was diagnosed in 10 cases (27%) as 7 cases (18.9%) showed leak through lumbar arteries and 3 cases (8.1%) showed leak through the inferior mesenteric arteries.Conclusion
CT angiography can accurately detect and classify endoleaks and thus determine line of treatment. Endoleaks are often asymptomatic and may become evident intra operatively or many years after the operation, therefore lifelong imaging supervision is necessary. 相似文献16.
Esam M. Hemat 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(1):115-123
Objective
To assess DWI and ADC value in characterization of orbital masses (differentiation of benign, inflammatory and malignant orbital masses).Patients & methods
Cross-sectional study included 38 patients, and diagnosed histopathologically, clinically and radiologically 26 with benign and inflammatory masses and 12 with malignant masses. Their ages ranged from 15 to 63 years. They were examined using 1.5 T MR machine.Results
There was a significant difference in ADC value of malignant and benign orbital masses. Malignant masses have a lower ADC values and restricted diffusion, compared with benign masses. Using 0.93 × 10?3 mm2/s as a cutoff value, in differentiating malignant from benign lesions, resulted in a total of 80% sensitivity, 83.3% specificity and 82% accuracy. Lesions with ADC values less than 0.87 × 10?3 mm2/s, had 90% likely to be of malignant nature. Lesions with ADC greater than 1.1 × 10?3 mm2/s, had 90% likely to be of benign nature. In between these two values, lesions are indeterminate.Conclusion
Diffusion weighted imaging with ADC value, can help in differentiating malignant from benign orbital masses. Malignant orbital masses have a significant lower ADC value than benign masses. We can use ADC cutoff value between malignant and benign masses. 相似文献17.
Mennatallah Hatem Shalaby Khaled A. Ali Shehata 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(4):791-798
Background
Ninety percent of hepatic cancers are hepatocellular carcinomas (HCC) which have an unfavorable prognosis. HCC is a hypervascular tumor supplied mainly by the hepatic artery. It has a higher blood supply than the surrounding hepatic tissue due to neovascularization. Computed tomography with perfusion imaging (CTP) is a non invasive tool which quantifies the blood flow parameters of HCC and compares it to the surrounding tissue.Purpose
To prove that CTP is a valuable diagnostic tool in diagnosis of HCC and posttherapeutic assessment.Patients and methods
One hundred and twenty-six HCC patients with 150 focal lesions are enrolled this study. Perfusion parameters are quantified and results are compared to those of triphasic CT.Results
CTP detected 141 lesions with 94% sensitivity and 40% specificity with elevated arterial perfusion (AP) and perfusion index (PI) with low portal flow (PF). It missed 5 lesions because of their hypovascularity and 4 lesions following radiofrequency ablation (RFA) and trans arterial chemo embolization (TACE).Conclusion
CTP is a safe and specific imaging tool for diagnosis and assessment of therapeutic interventional procedures in HCC. 相似文献18.
Mennatallah Hatem Shalaby Sherin M. Sharara Mohammed H. Abdelbary 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(3):645-652
Background
The ankle is frequently injured in trauma, overuse syndrome and inflammatory processes. Different imaging modalities assess the ankle, including plain radiography, computed tomography (CT), magnetic resonance imaging (MRI), and ultrasonography (US).Purpose
Our objective is to assess the role of high resolution US as a valuable tool in the depiction of causes of ankle joint pain.Patients and methods
The study included 28 patients presented with ankle pain ranging in age from 17 to 60 years. They were examined by US and findings were correlated with MRI.Results
US was capable to detect various lesions (synovitis, arthritis, plantar fasciitis, tendon and ligamentous lesions). It had a sensitivity of 95.4%, a specificity of 83.3% and an overall accuracy of 92.8%. US had a limited value in detection of avascular necrosis (AVN), bone marrow oedema and fractures.Conclusion
US can be used as a first step diagnostic tool in cases of ankle pain. MRI should be spared to cases with negative or equivocal US findings. 相似文献19.
Omar Hassanen Usama Ghieda Mohamed A. Eltomey 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(4):1117-1123
Objective
The prognosis of different histologic subtypes of RCC varies and affects management. Patients with chromophobe or papillary RCC have better prognosis than those with clear cell RCC. The aim of our work was to study the utility of DCE and DWI in the preoperative prediction of renal cell carcinoma subtypes, using histopathology as a gold standard method of diagnosis.Patients and methods
Thirty five patients with 38 renal masses were included in the study. All had DCE MRI studies with DWI sequences, CER and ADC values calculation for normal and diseased renal tissues.Results
The Mean ADC value of normal renal parenchyma was significantly higher than RCC. The CER and ADC values for Clear cell RCC were higher than Papillary and Chromophobe RCC. No statistically significant difference was found between the CER & ADC values for Papillary and Chromophobe RCC. CER & ADC values of clear RCC were higher than non clear RCC.Conclusions
DCE MRI in addition to DWI & ADC appears as a very helpful imaging tool in the differentiation between clear cell and non-clear cell RCCs. 相似文献20.
Aya S. Al-Rawy Mohammad al-Shatouri Mohammed El Tabbakh Azza A. Gad 《The Egyptian Journal of Radiology and Nuclear Medicine》2017,48(4):877-884