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1.

Objective

To assess the efficiency of dual energy contrast enhanced mammography in the assessment of the indeterminate breast lesions (BIRADS 3 and BIRADS 4).

Materials and methods

34 female having 39 indeterminate breast lesions (BIRADS 3 and BIRADS 4) by digital mammography were further examined by dual energy contrast enhanced mammography. Two images were acquired at low and high energy in MLO view after 2 min and in CC view at 4 min post iodinated contrast injection (1.5 ml/kg with flow of 4 ml/s). Images were processed to obtain subtracted images to enhance the areas of the contrast uptake.

Results

Results from pathology were detected for all cases. Contrast enhanced digital mammography showed specificity, sensitivity, PPV, NPV, FDR, FPR and accuracy of 93.75%, 91.3%, 88.2%, 95.4%, 11.7%, 8.6% and 92.3% respectively compared to full field digital mammography which were 68.75%, 69.5%, 61.1%, 76.1%, 38.8%, 30% and 69.2% respectively.

Conclusion

Contrast-enhanced digital mammography is a useful tool to be used for breast cancer detection especially in indeterminate lesions (BIRADS 3 and 4).  相似文献   

2.

Background

Ultrasound and mammography alone may not always identify malignant breast lesions. Samsung Medison has added the Smart detect? (S-detect?) program to its ultrasound features, and this may improve the identification of benign and malignant breast lesions.

Objective

To evaluate the accuracy of S-detect?, a new ultrasound added feature, and to identify benign and malignant breast lesions in women with symptoms or signs of focal breast disease.

Methods

In a pilot study, the registered data of a selected 45 women is retrospectively audited and analyzed. These women, presenting with clinical symptoms of breast disease (diagnostic), were examined by mammography and ultrasound. The interpretation and Hand Held Ultrasound (HHUS) have been done with 2 radiologists determining the BIRADS® classification results for every woman (benign or malignant). In addition, S-detect? was applied during the ultrasound examination, and S-detect? findings (benign or malignant) were recorded in either concordance or discordance with radiologists’ findings. Biopsy was performed as a gold standard.

Results

Among the enrolled 45 women in the study, 33 (73.3%) had concordant results with the radiologists while the remaining 12 (26.6%) were discordant, in 10 (22.2%) of the 12 discordant cases, S-detect? findings of benign contradicted radiologists’ findings and in 2 of the cases, S-detect? findings of malignant contradicted radiologists’ findings. In the 10 discordant cases where S-detect? recommended benign, only 2 were correct, but in the 2 discordant cases where S-detect? recommended malignant, both were correct. The overall accuracy of S-detect? was 82.22%, sensitivity 61.90%, but a specificity was 100%.

Conclusion

The use of S-detect? in this study identified additional cases of malignancy, so this technology may be a useful tool in addition to mammography and US for the diagnosis of breast disease. The specificity of the S-detect? in this study is remarkably high; yet, the sensitivity is low. Despite a small number of cases, we suggest a larger scale study, to validate the clinical utility in using the B-mode plus S-detect? to enhance diagnosis in patients presenting with symptoms and signs of breast diseases.  相似文献   

3.

Aim of the work

To evaluate the role of diffusion weighted imaging (DWI) in the planning for CT guided biopsy of lung and mediastinal lesions.

Subjects and methods

This cross sectional study included 23 patients with mean age was 42.7?years came with clinical and imaging suspicion of chest malignancy, referred for CT guided transthoracic biopsy. DWI and apparent diffusion coefficient (ADC) were evaluated for all patients to choose the area of maximum restriction.

Results

The study showed that with DWI guidance; all the biopsy specimens were diagnostic and provide adequate material for analysis.

Conclusion

DWI and measurement of ADC value has a very helpful role in the pre-procedural planning of transthoracic biopsies.  相似文献   

4.

Aim

Assess accuracy of contrast enhanced spectral mammography (CESM) versus conventional mammography and ultrasound in evaluation of BI-RADS 3 and 4 breast lesions with pathological correlation.

Patients and methods

Thirty female patients with 35 breast lesions diagnosed by conventional imaging as BI-RADS 3 and 4, presented to Women’s Imaging Unit of Radiology Department between January and December 2015, age ranged from 23 to 70 years. All patients underwent conventional mammography and ultrasound then CESM.

Results

Patients divided into two groups, benign and malignant lesions group according to histological analysis. Mammography results that malignant lesions detected in 18/35 (51.4%) while benign lesions 17/35 (48.6%). Ultrasound revealed 27/35 (77.1%) lesions were malignant and 8/35 (22.9%) lesions benign. But CESM, revealed 25/35 (71.4%) lesions were malignant & 10/35 (28.6%) lesions benign. Among 7 patients with multifocal/ multi-centric histologically proven malignant lesions, all detected by CESM 7/7 cases (100%) versus 2/7 cases (28.6%) and 6/7 cases (85.7%) detected by mammography and ultrasound respectively. Based on, CESM had 95.2% sensitivity and 82.9% diagnostic accuracy.

Conclusion

CESM has better diagnostic accuracy than mammography alone and mammography plus ultrasound. CESM has 82.9% diagnostic accuracy in comparison to 51.4% for mammography and 77.1% for ultrasound.  相似文献   

5.

Objective

To assess the diagnostic accuracy of diffusion weighted imaging (DWI-MRI) being a non-contrast based MR sequence versus dynamic contrast enhanced MRI (DCE-MRI) in the preoperative loco-regional staging of the cervical carcinoma.

Methodology

Fifty cases of proved cancer cervix prior staging subjected to dynamic post contrast technique: one pre-and six post contrast phases (40?s each). DWI was scanned using different b values and ADC values were measured.

Results

DWI was the most accurate in staging operable cases (93.3%).Parametrial infiltration was overestimated in 3 cases versus 4 cases in DCE-MR. DWI showed 100% sensitivity, positive predictive value and accuracy in the assessment of locally advanced carcinomas. In metastatic lymph nodes, DCE-MR showed the least accuracy of 86%.

Conclusion

DWI is helpful in discriminating local from locally advanced cervical carcinomas. DCE-MR can delineate cervical carcinomas confined to the uterus and exclude bladder/rectal invasion.  相似文献   

6.
Perianal fistula is a common disorder with high tendency to recur in spite of satisfactory surgery. Pelvic MRI is the preferable imaging modality for recognition and assessment of perianal fistulas.

Aim of the work

To evaluate the effectiveness of MRI in grading of primary perianal fistula and verification of its associated findings in correlation with surgical outcome.

Subjects and methods

This prospective study included 30 patients with age range 14–44 years. Preoperative MR grading was correlated with surgical outcome.

Results

The sensitivity, specificity, PPV, NPV and weighted Kappa of MR grading in correlation with surgery was 95.8%, 83.3%, 95.8%, 83.3% and 0.79 respectively with P value = 0.000

Conclusion

MRI is a valuable modality for grading of primary perianal fistula and its complications. Accurate pre-operative grading may reduce the surgical complications and possibility of recurrence.  相似文献   

7.

Background

The ankle is frequently injured in trauma, overuse syndrome and inflammatory processes. Different imaging modalities assess the ankle, including plain radiography, computed tomography (CT), magnetic resonance imaging (MRI), and ultrasonography (US).

Purpose

Our objective is to assess the role of high resolution US as a valuable tool in the depiction of causes of ankle joint pain.

Patients and methods

The study included 28 patients presented with ankle pain ranging in age from 17 to 60 years. They were examined by US and findings were correlated with MRI.

Results

US was capable to detect various lesions (synovitis, arthritis, plantar fasciitis, tendon and ligamentous lesions). It had a sensitivity of 95.4%, a specificity of 83.3% and an overall accuracy of 92.8%. US had a limited value in detection of avascular necrosis (AVN), bone marrow oedema and fractures.

Conclusion

US can be used as a first step diagnostic tool in cases of ankle pain. MRI should be spared to cases with negative or equivocal US findings.  相似文献   

8.

Background and purpose

Consistency of pituitary macroadenoma is a crucial information for neurosurgeons. We aimed to assess the role of DW-MRI as non invasive imaging modality in predicting the tumour consistency of pituitary macroadenoma.

Materials and methods

Twenty patients with pituitary macroadenoma underwent conventional MR imaging sequences, pre contrast, post contrast MRI and diffusion weighted MRI with ADC map. The tumour consistency was determined both macroscopic by neurosurgeons and microscopic by histopathologists.

Results

Our study included 12 soft, 4 intermediate and 4 hard tumours. The tumour consistency and the collagen contents were correlated with diffusion and ADC values. The mean ADC value of patients with soft tumours was 0.54?×?10?3?mm2/s while for intermediate tumour was 0.82?×?10?3?mm2/s and for hard tumours was 1.11?×?10?3?mm2/s. Soft and intermediate consistency tumours were successfully managed by endoscopic transsphenoidal approach; suction and curettage. While, hard tumours could not be managed by the transsphenoidal approach and needed further transcranial procedure with sensitivity 95% and specificity 95%.

Conclusion

DWI-MRI is a useful tool to predict the pituitary macroadenoma consistency and the suitable surgical approach for resection.  相似文献   

9.

Aim and objectives

To evaluate the diagnostic accuracy of elastosonographyin prediction of malignancy in solitary thyroid nodule.

Methodology

60 patients (37 females and 23 male) with solitary thyroid nodule were included, their age ranged from 21 to 52?years (mean age 30.6?years), grey scale, color-power Doppler US and elastography were performed for all patient.

Results

Presence of hypoechogenicity, absent halo sign, irregular margins, microcalcifications and predominant intranodular vascularity were the most US patterns predictive of malignancy. Suspicious nodule by elastography (Astria score 3 and 4) were found in 19 nodules (31.7%), 9 of them were benign and 10 of them were malignant with sensitivity 58.82%, specificity 79.07% and accuracy 73.33%, combined suspicious US findings (TIRAD 4&5) and suspicious elastography score (3&4) were most predictive of malignancy which was found in 16 out of 17 nodules with sensitivity 94.12%, specificity 76.74% and accuracy 81.67%.

Conclusion

Combined gray scale, color Doppler US and elastography were more sensitive and accurate than US features alone in prediction of malignancy of solitary thyroid nodules with sensitivity 94.12%, specificity 76.74% and accuracy 81.67%.  相似文献   

10.

Objective

To detect if strain ultrasound elastography and strain ratio have additional value to the conventional grey scale ultrasound in predicting thyroid malignancy.

Patients and methods

This study included 92 thyroid nodules from 62 patients (the mean age was 40.64?±?13.93). Morphologic aspects of the thyroid nodule in conventional grey scale ultrasonography and elastographic examinations with elastography score and strain ratio (SR) were performed for all nodules. The final diagnosis was confirmed by fine needle aspiration biopsies in 72 nodules and by excisional biopsies in 20 nodules.

Results

We found that combination of both conventional ultrasound and strain elastography score have the best diagnostic performance with sensitivity, specificity, PPV, NPV and accuracy accounting for 80%, 97%, 57%, 99% and 96% respectively. The means SR for benign nodules (1.37?±?0.56) was significantly lower than that for malignant nodules (3.0?±?0.71) [p-value .003].The optimal SR cutoff is 2.5 with estimated 80% sensitivity, 98% specificity, PPV 67%, NPV 99% and accuracy 97%.

Conclusion

The clinical application of elastography score and SR should be carried out hand in hand with conventional sonographic assessment of thyroid nodules to achieve the best diagnostic performance.  相似文献   

11.

Background

Lateral epicondylitis is referred to a degenerative disorder that affects the common extensor tendon (CET) where it attaches to the lateral epicondyle of the humerus. Nowadays, one of minimally invasive interventions is platelet-rich plasma (PRP) injection that had been explored in some controlled clinical studies to show its effectiveness in treating lateral epicondylitis through inducing inflammation rather than suppressing it.

Objectives

The aim of our study was to investigate the effectiveness of ultrasound guided platelet-rich plasma (PRP) injection in treating chronic lateral epicondylitis in addition to identifying the potential sonographic morphological changes in the common extensor tendon (CET) after PRP injection.

Results

Statistical analysis showed high significant improvement in all ultrasound findings of common extensor tendon (CET) including echotexture, thickness, cross section, partial tear and calcification in majority of patients.

Conclusion

We concluded that US-guided platelet-rich plasma (PRP) injection for treatment of lateral epicondylitis was a safe, minimally invasive and effective procedure in improving the sonographic and pathological changes of common extensor tendon (CET).  相似文献   

12.

The aim of the study

Is to compare the role of minimum intensity projection (MinIP) images with that of volumetric high resolution computed tomography (HRCT) images in the diagnosis of interstitial lung diseases (ILD).

Patients and methods

180 patients (149 females and 31 males) were included in this prospective study that took place over a duration of two and half years. All patients underwent HRCT and MinIP images. The positive findings were compared recording which technique was better and if MinIP adds a value in reaching an accurate diagnosis.

Results

MinIP images showed better visualization of traction bronchiectasis, ground glass opacities and mosaic attenuation pattern, as well as, the cystic lung changes seen in LAM. While MinIP did not add a significant value in thick-walled cystic changes e.g.: honeycombing.

Conclusion

MinIP is one of the multiplanar techniques of HRCT that proved throughout our study to be an informative complementary tool increasing the observer confidence and agreement regarding some findings as compared with HRCT alone.  相似文献   

13.

Purpose

Evaluation of the role of real-time elastography in differentiating between benign and malignant cervical lymph nodes (LNs), comparison with B-mode and Doppler Ultrasonography.

Patients and methods

This prospective study included 30 patients, with cervical lymphadenopathy, their age ranged from (18–79 years). The total number of the examined lymph nodes (LNs) was 75 LNs. These (LNs) subjected to B-mode US followed by Doppler evaluation, then elastographic evaluation including strain ratio which was calculated for each lesion, and compared with the histological results after fine needle aspiration cytology.

Results

We evaluate the size, shape, echogenicity, and hilum on the B-mode images. The presence of the hilum showed the highest accuracy & sensitivity. Doppler Ultrasonography evaluation of nodal vascular pattern was of high sensitivity & specificity. The calculated sensitivity of elastographic pattern and scoring was 86%, specificity was 100%, PPV and NPV were 100% and 78.1% respectively, and the total accuracy was 90%. The mean elastographic strain ratio for malignant LNs (3.4 ± 1.2) was significantly greater than that for benign LNs (mean, 1.2 ± 0.3).

Conclusion

Elastography is a promising improvement for differentiation between benign and malignant cervical lymphadenopathy. Sensitivity and specificity of elastography increased especially if combined with gray scale US and Doppler US.  相似文献   

14.

Background

Characterization of tendo-ligamentous pathologies of wrist remains problematic, despite advances in imaging. By using clinical history and imaging appearance, one can determine the diagnosis. USG is used as first imaging modality whereas MRI aids in making a specific diagnosis of few of the lesions.

Aims

To investigate the etiological spectrum of tendo-ligamentous pathologies of wrist on USG & MRI with statistical correlation.

Patients and methods

80 patients (male/female = 46/34) with complaint of swelling or pain in wrist were included and underwent USG and MRI of both the wrists.

Results

The spectrum included ganglion cysts, vascular malformations, tenosynovitis, tendinopathy, ligament tears and fibrosis. The analysis was done using kappa coefficient and spearman's rho correlation coefficient. The strength of agreement between USG and MRI for the diagnosis of ganglion cysts, vascular malformations, tenosynovitis and tendinopathy was found to be very good.

Conclusion

USG provides detailed depiction of superficial structures, is less expensive, and allows dynamic examinations of the wrist. It should be the first choice of investigation for majority of the cystic, tendinous, vascular, and fibrotic pathologies of the wrist. However, less promising results were observed for ligamentous pathologies on USG in our study.  相似文献   

15.

Introduction

Elastography is considered a non-invasive imaging modality which determines the tumors according to their stiffness. Strain images representing the stiffness of the lesions compared to that of the surrounding normal tissue.

Purpose

To prospectively evaluate the sensitivity and specificity of the real-time sonoelastography together with B-mode US for distinguishing benign from malignant breast lesions.

Methods

The study was conducted on 80 patients, each patient was subjected to complete history taking, thorough clinical examination. All patients had conventional US and elastography using Hitachi 7.5?MHz linear probe (Hitachi hi vision avirus ultrasound), while only in 68 patients mammography was done.

Results

Among the 80 patients, sensitivity and specificity of the elastography test of breast lesions according to the elastography score were 80% and 80.95% respectively, while sensitivity and specificity of conventional B mode US were 80% and 76% respectively and the combined B mode US and US elastography showed higher sensitivity and specificity of 86.6% and 90.4% respectively.

Conclusion

Elastography is a non-invasive imaging technique which is done in the same session of ultrasound in an attempt to increase and improve the accuracy of diagnostic efficiency of ultrasound.  相似文献   

16.

Background

Ninety percent of hepatic cancers are hepatocellular carcinomas (HCC) which have an unfavorable prognosis. HCC is a hypervascular tumor supplied mainly by the hepatic artery. It has a higher blood supply than the surrounding hepatic tissue due to neovascularization. Computed tomography with perfusion imaging (CTP) is a non invasive tool which quantifies the blood flow parameters of HCC and compares it to the surrounding tissue.

Purpose

To prove that CTP is a valuable diagnostic tool in diagnosis of HCC and posttherapeutic assessment.

Patients and methods

One hundred and twenty-six HCC patients with 150 focal lesions are enrolled this study. Perfusion parameters are quantified and results are compared to those of triphasic CT.

Results

CTP detected 141 lesions with 94% sensitivity and 40% specificity with elevated arterial perfusion (AP) and perfusion index (PI) with low portal flow (PF). It missed 5 lesions because of their hypovascularity and 4 lesions following radiofrequency ablation (RFA) and trans arterial chemo embolization (TACE).

Conclusion

CTP is a safe and specific imaging tool for diagnosis and assessment of therapeutic interventional procedures in HCC.  相似文献   

17.

Aim

To evaluate accuracy of DWI in evaluating HCC response to DEB TACE and compare the results with DCE MRI.

Material and methods

42 patients with 59 lesions underwent precontrast abdominal MRI, DWI, ADC map with ADC value measurement and DCE MRI. The qualitative DWI and ADC values were correlated to the DCE MR findings.

Results

Comparing the qualitative DWI findings to DCE MRI, showed sensitivity of 83.9%, specificity of 64.3%, positive predictive value of 72.2%, and negative predictive value of 78.3% and overall accuracy of 74.5%. The measured ADC values showed significant difference (P value <0.05) between the ADC values measured in the active tumoral areas and necrotic areas with no significant difference between areas of active tumoral enhancement in the different groups. ROC analysis for ADC values showed area under curve 0.7 and maximum combined sensitivity and specificity of 79% and 69.6% respectively at cutoff ADC value of 1.395?mm2/sec.

Conclusion

DWI is useful highly sensitive technique in evaluation of HCC response to DEB TACE, yet it has low specificity related to high number of false positive results preventing using it solely. Also, DWIs is a reliable method in differentiation between active tumor residue/recurrence and benign perilesional enhancement.  相似文献   

18.

Objectives

To create a systematic approach using computed tomography (CT) and magnetic resonance imaging (MRI) findings to facilitate identifying the etiology of hearing loss, evaluating the anatomy for surgery, and predicting complications.

Methods

Twenty nine pediatric patients with congenital or acquired sensory-neural hearing loss (SNHL) requiring cochlear implant (CI) were included. They underwent combined CT, 3D DRIVE MRI axial plane and axial T2WIs for the whole brain. The inner ear, cochlear nerve development, temporal bone anatomy, operative window, normal variants and causes of central hearing loss were assessed.

Results

CT showed that 100% of the patients are suitable for CI while MRI showed that 96.5% of studied patients are suitable. The examined ears were categorized into 4 groups according the candidacy for operation; 86.2% were suitable for CI, 5.1% were suitable for CI but with expected poor response, 1.7% of examined ears were suitable for CI with modification of surgical procedure and 6.8% were not suitable for CI.

Conclusion

In Suez Canal area, the combined CT/MRI approach categorized the majority of patients with SNHL (96.6%) as good candidates for CI.  相似文献   

19.

Objective

The aim of this study was to highlight the role of MRI in detecting and diagnosing trigeminal nerve neoplastic lesions.

Patients and methods

56 patients included in our study presented with trigeminal symptoms with or without other neurological symptoms, subjected to conventional MRI sequences and 3D sequences as (CISS) and T1 magnetization-prepared rapid acquisition gradient echo (MP-RAGE). The inclusion criteria included patients with intracranial neoplastic lesions involving the trigeminal nerve and/or its branches.

Results

28 patients met our inclusions criteria and subjected to statistical analysis; 19 patients were females and 9 were males ranging between 15 and 70?years with a mean age of 47.5?years. 14 lesions were benign and 14 were malignant, and were distributed according to final diagnosis as meningiomas (10 cases), lymphoma (6 cases), deposits (4 cases), nasopharyngeal carcinoma (4 cases) schwannoma (3 cases), and neurofibroma (one case). The most frequent involved segments of the trigeminal nerve was simultaneous involvement of both Meckel’s cave and cavernous sinus in nine cases (32%).

Conclusions

MRI is very helpful in demonstrating the whole intra-cranial course of the trigeminal nerve and in diagnosing various neoplastic lesions involving the nerve, and thus providing full roadmap before management.  相似文献   

20.

Objective

Vaginal or uterine outlet obstruction leads to hematocolpos or hematometra. Detection of the etiology of this entity is important to guide adequate surgical management and thereby avoid complications and to preserve fertility. The aim of this study was to evaluate obstructing vaginal malformations in adolescent girls presenting with hematocolpos or hematometra with MR imaging.

Materials and methods

A hospital based prospective study was conducted in a tertiary care centre from September 2015 to October 2016. The study included 17 adolescent females who were evaluated with MRI.

Result

Of 17 adolescent female with vaginal or uterine outflow obstructive anomalies with hematocolpos or hematometra, where 6 patients (35.3%) had HWWS, 6 patients (35.3%) had imperforate hymen, 2 patients (11.8%) had transverse vaginal septum, 1 patient each (5.9%) had cervico-vaginal atresia, unicornuate uterus and communicating rudimentary Uterine horn. MRI revealed hematocolpos in 15 patients (88.2%), hematometra in 13 patients (76.5%), endometriotic ovarian cysts in 6 patients (35.3%) and hematosalpnix in 3 patients (17.6%).

Conclusion

Early radiological diagnosis of the cause of vaginal or uterine outflow obstruction is important to guide adequate surgical management which if undertaken promptly helps to avoid complications due to reflux from vaginal or uterine outflow obstruction.  相似文献   

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