非球面人工晶状体植入术后视功能的临床研究

目的:评价Canon Staar KS—3Ai非球面人工晶状体(IOL)对提高年龄相关性白内障患者术后视功能的作用。方法:年龄相关性白内障患者98例(126眼)随机分成两组。在白内障超声乳化吸除术后,观察组52例(65眼)植入非球面IOL(Canon Staar KS—3Ai),对照组46例(61眼)植入球面IOL(Allergan Sensor AR40e)。观察患者术后的裸眼视力(uncorrected visual activity,UCVA)、最佳矫正视力(best corrected visual activity,BCVA)、屈光状态、对比敏感度(contrast sensitivity,CS)、波前像差的均方根(root mean square,RMS)值。随访时间为术后6mo。结果:术后6mo两组UCVA、BCVA、屈光状态差异无统计学意义。无眩光环境下12,18c/d空间频率和眩光环境下6,12,18c/d空间频率上观察组CS明显优于对照组。在瞳孔直径6mm时,观察组4阶像差、4阶球差、总高阶像差RMS值低于对照组。在瞳孔直径6mm时3阶像差、5阶像差RMS值及瞳孔直径3mm时两组高阶像差RMS值差异无统计学意义。结论:非球面IOL眼视觉质量明显优于球面IOL眼。     

AcrySof IQ人工晶状体植入术的临床效果观察

目的:探讨白内障超声乳化联合蓝光滤过型非球面人工晶状体植入术的临床效果。方法:年龄相关性白内障患者80例(80眼),术中植入AcrySof IQ人工晶状体为观察组,植入AcrySof Natural人工晶状体为对照组。观察术后1wk不同视标对比度的视力;使用主观像差仪检查实验组术后1mo的像差,依35项Zernike系数计算总像差及4阶像差的均方值(root means quare,RMS),比较实验组与对照组间的差异。结果:术后1wk,视标对比度为100%时,两组间差异无统计学意义(P<0.05)。对比度为25%时,两组间差异有统计学意义(P>0.05)。术后1mo,实验组与对照组总体像差的RMS均值分别为0.84±0.21μm及1.44±0.42μm,两者之间的差异有统计学意义。实验组、对照组4阶像差(球差)的RMS均值为0.58±0.18μm、1.14±0.37μm,两者之间的差异有统计学意义。结论:非球面人工晶状体可以减少术眼光学像差(尤其是球差),获得更好的低对比度视力,从而提高术后的视觉质量。     

Acri.Smart 36A非球面人工晶状体临床应用研究

目的探讨Acri.Smart36A非球面人工晶状体对人工晶状体眼视觉质量和波前像差的影响。方法选择老年性白内障患者24例30眼,随机分为2组,植入非球面设计的Acri.Smart36A人工晶状体(Acri.Smart36A组)15眼和植入球面设计的Acri.Smart46S人工晶状体15眼(Acri.Smart46S组),比较两组术后3个月最佳矫正视力、对比敏感度(眩光和无眩光条件下,6.3°、4.0°、2.5°、1.6°、1.0°空间频率下)、像差(尤其眼内球差)的差异。结果术后3个月,Acri.Smart36A组最佳矫正视力为0.87±0.16,Acri.Smart46S组为0.85±0.18,差异无统计学意义(P>0.05)。术后Acri.Smart36A组患者对比敏感度除眩光条件下1.0°及无眩光条件下1.6°空间频率之外其余各空间频率均较Acri.Smart46S组好(均为P<0.05)。术后Acri.Smart36A组总球差为(-0.060±0.355)μm,眼内球差为(-0.283±0.177)μm;Acri.Smart46S组总球差为(0.145±0.137)μm,眼内球差为(0.072±0.159)μm,差异均有统计学意义(均为P<0.05)。结论相较球面人工晶状体,Acri.Smart36A非球面人工晶状体能减少眼内球差,提高对比敏感度、眩光敏感度,提高视觉质量。     

微切口超声乳化加非球面人工晶状体植入治疗白内障的临床评价

目的:探讨超声乳化联合非球面人工晶状体植入对白内障患者术后视觉质量的影响.方法:年龄相关性白内障患者(50例63眼)随机分为试验组25例33眼和对照组25例30眼,两组患者手术方法相同,试验组植入非球面人工晶状体,对照组植入球面人工晶状体;比较术后裸眼视力、最佳矫正视力,并检查两组患者对比敏感度和像差.结果:术后1wk;1,3mo两组患者裸眼视力相比差异无统计学意义(P＞0.05),术后3mo两组最佳矫正视力相比差异亦无统计学意义(P＞0.05).在非眩光和眩光条件下,两组患者在3.0,6.0,12.0,18.Ocd频段下对比敏感度比较差异无统计学意义(P＞0.05);在1.5cd频段下,试验组对比敏感度值显著高于对照组,组间比较差异具有统计学意义(P＜0.05);术后3 mo试验组球差、彗差均显著低于对照组,两组间比较差异具有统计学意义(P＜0.05).结论:非球面人工晶状体在低频段对比敏感度显著优于球面人工晶状体,并能够降低白内障患者术后的总像差,从而提高白内障患者术后的视觉功能.     

三种非球面单焦点丙烯酸酯IOL植入术后暗视下视觉质量的观察

目的: 研究三种非球面丙烯酸酯人工晶状体(intraocularlens,IOL)植入术后患者在最佳矫正视力及暗视下(3cd/m2)对比敏感度(contrast sensitivity,CS)的变化,评价白内障超声乳化联合单焦点非球面丙烯酸酯IOL植入术后患者的视觉质量。方法: 选取符合条件的年龄相关性白内障患者77例90眼,2011-12/2012-11于我院行白内障超声乳化吸除联合IOL植入术,术前将患者随机分成三组,1组(25例30眼)植入疏水性染黄色丙烯酸酯IOL(HOYA),2组(28例30眼)植入亲水性丙烯酸酯IOL(Rayner)及3组(24例30眼)植入亲水性丙烯酸酯表面肝素处理IOL(XO)。所有患者于术后1,3mo均行最佳矫正视力(标准对数视力表)检查及暗视无眩光状态下的CS检查,所得结果进行统计学分析。结果: 患者术后1,3mo时,各组之间最佳矫正视力无明显统计学差异(P>0.05);患者1,3mo暗视无眩光状态下CS结果(标准化后的CS值:lgCS),三组患者之间CS值并无统计学差异(各组之间P>0.05),但HOYA组患者CS结果略下降。结论: 三组患者之间,术后1,3mo时最佳矫正视力及对暗视无眩光状态下CS结果无明显差异(P>0.05)。由于蓝光滤过型IOL对视网膜的潜在保护作用,因此植入染黄色滤过蓝光的IOL是可取的,特别是对儿童及青年白内障患者是必要的。     

非球面与球面人工晶状体植入术后对比敏感度的比较

目的观察非球面人工晶状体（IOL）和球面IOL植入术后在视力相同的情况下其对比敏感度的差异。方法收集行超声乳化联合IOL植入术的年龄相关性白内障患者49例（60眼）,其中植入非球面IOL Tecnis ZA9003者24例30眼,植入球面IOL Sensar AR40e者25例30眼,所有病例术后裸眼LogMAR视力均〉0．1。术后3个月时采用CSV-1000对比敏感度测试仪分别测量明视、暗视和眩光状态下的对比敏感度,用F．A．C．T对比敏感度表测量近距离对比敏感度。结果在明视和暗视状态下的对比敏感度,非球面IOL组均高于球面IOL组,两组在空间频率6、12、18周／度时的差异均有统计学意义（P〈0．05）;暗视眩光状态下的对比敏感度,非球面IOL组高于球面10L组,两组在各空间频率的差异均有统计学意义（P〈0．05）。F．A．C．T对比敏感度测试卡测得的对比敏感度,非球面IOL组高于球面IOL组,两组在各空间频率的差异均有统计学意义（P〈0．05）。结论在传统的视力表检查视力正常和相同的情况下,非球面IOL植入术后较球面IOL植入术后患眼具有较好的对比敏感度,提示非球面IOL可以提高功能视力。     

非球面人工晶体的临床研究

目的客观评价非球面人工晶体、多焦点人工晶体和单焦点人工晶体的临床疗效。方法选择行白内障超声乳化联合人工晶体（IOL）植入术的患者90例,分成三组,植入Tecnis IOL 30例、Array IOL 30例及Sensar IOL 30例。观察患者手术后1w、3m的远、近视力,术后3m三组的对比敏感度、视觉症状和生存质量等变化。结果手术后1w、3m三组间近视力两两进行比较,P值均〈0.05,三组间差异均有统计学意义,其中Array组近视力最好,Tecnis组其次,Sensar组相对较差。术后1w、3m三组间远视力两两进行比较,P值均〉0.05,三组间无统计学意义。术后3m三组间在无眩光背景下对比度值比较,P值均〈0.05,故三组间差异性均有显著性,其中Tecnis组对比度值最小,即对比敏感度最好,Sensar组其次,Array组对比度值最大,即对比敏感度相对较差。术后3m三组间在有眩光背景下对比度值比较,Tecnis组与Array组比较P〈0.05,Tecnis组与Sensar组比较P〈0.05,差异具有显著性;Array组与Sensar组比较P〉0.05,无显著性差异性;故在有眩光背景下Tecnis组对比度值最小,即对比敏感度最好,而Array组与Sensar组两组无明显差异性。术后3m三组间暗适应时间比较,P值均〈0.05,故三组间差异性均有显著性,其中Tecnis组暗适应时间最短,Sensar组其次,Array组暗适应时间最长。术后3m三组间视功能量表分值比较P〉0.05,故三组间视功能质量无显著性差异。结论对于患有老年性白内障施行超声乳化联合IOL植入术的患者来说,无论植入何种IOL,手术后均可大大提高和改善患者的视功能和生存质量。但在IOL的选择上,植入多焦点人工晶体可以使患者获得较好的近视力,但伴有对比敏感度的下降,植入非球面人工晶体可以获得相对较好的对比敏感度,避免了术后眩光、光晕和夜间视力下降等不良现象的发生,提高视觉质量。     

非球面人工晶状体与球面人工晶状体的比较

随着波前像差技术的发展,人们对影响白内障术后视功能的因素有了更深刻的认识,设计出旨在降低人工晶状体眼球面像差从而提高视功能的非球面人工晶状体。现就非球面人工晶状体眼与球面人工晶状体眼相比,在视功能、波前像差等方面有何差异,非球面晶状体的优越性,以及影响优越性表现的因素综述如下。     

新型衍射型非球面多焦点人工晶状体的临床应用

目的比较白内障超声乳化联合植入新型衍射型非球面多焦点人工晶状体Tecnis AMO00及非球面单焦点人工晶状体Tecnis的临床效果。方法选择老年性白内障患者,根据植入的晶状体不同分为2组:多焦点组46例62眼,植入Tecnis AMO00新型衍射型非球面多焦点人工晶状体,单焦点组42例68眼,植入Tecnis非球面单焦点人工晶状体。术后1个月和3个月随访,观察术后裸眼远视力、裸眼近视力、最佳矫正远视力、最佳矫正近视力及中间距离视力,术后3个月进行角膜内皮计数及角膜地形图检查,问卷调查了解视觉症状和视觉满意度。结果术后1个月及3个月两组间患者裸眼远视力、最佳矫正远视力和最佳矫正近视力均无显著差异。术后1个月及3个月多焦点组裸眼近视力分别为0.65±0.27和0.68±0.28,中间距离视力分别为0.64±0.22和0.67±0.25,相比单焦点组术后1个月及3个月的裸眼近视力(分别为0.28±0.26和0.30±0.25)和中间距离视力(分别为0.27±0.25和0.29±0.27),具有明显优越性,差异均有统计学意义(均为P<0.05)。两组患者术前、术后的散光状态差异均有统计学意义(均为P<0.01),术前、术后的角膜内皮细胞计数差异亦均有统计学意义(均为P<0.01),两组之间术后角膜内皮细胞丢失率差异无统计学意义(P>0.05)。多焦点组脱镜率(96.77%)明显高于单焦点组(25.00%),差异有统计学意义(P<0.01)。多焦点组4例患者诉轻度光晕、眩光,但在可以忍受范围内。结论新型衍射型非球面多焦点人工晶状体Tecnis AMO00能提供良好的全程视力,有效降低患者对老视镜的依赖,提高白内障患者术后的视觉质量。     

Comparison of visual function following implantation of Acrysof Natural intraocular lenses with conventional intraocular lenses

BACKGROUND: Recently an intraocular lens (IOL) has been introduced which blocks blue light. As blocking blue light may be to the patient's detriment, this study was designed to evaluate visual function following implantation of a blue-blocking (Acrysof Natural) IOL. METHODS: Patients were recruited for this non-randomized controlled interventional study, from those attending a private rural ophthalmology clinic for cataract surgery (n = 93). Only those who had previously had a conventional IOL implanted into one eye were offered an Acrysof Natural IOL for the second eye. Postoperatively patients underwent refracted Snellen visual acuity, contrast sensitivity using a CSV-1000E instrument and colour vision testing using a Farnsworth D-15 test, with a subset (n = 20) undergoing a Farnsworth-Munsell 100-Hue test. Results were then compared between eyes. Finally, a subset (n = 63) completed a survey designed to assess the subjective impact of the Acrysof Natural IOL. RESULTS: There were no statistically significant differences between eyes implanted with conventional IOLs compared with Acrysof Natural IOLs for visual acuity (t = 0.57; P = 0.57), contrast sensitivity (t = 0.43; P = 0.67 for 3 cycles per degree [cpd], t = 0.56; P = 0.58 for 6 cpd, t = 0.09; P = 0.93 for 12 cpd and t = 0.16; P = 0.87 for 18 cpd) or colour vision with the Farnsworth D-15 (Chi(2) = 0.38; P = 0.55) or the Farnsworth-Munsell 100-Hue test t = 0.34; P = 0.74). Most subjects reported that they could not tell a difference between the two IOLs subjectively or that any difference experienced was not significant. CONCLUSION: Our sample did not show any significant differences between eyes implanted with conventional IOLs and the Acrysof Natural IOL. We would suggest that the Acrysof Natural IOL may be used without any significant difference in visual function.     

亲水性非球面与球面人工晶状体植入术后高阶像差的研究

目的：比较亲水性球面和非球面人工晶状体（intraocular lenses,IOL）对术后高阶像差（higher order aberrations,HOA）的影响。方法：66例78眼行白内障超声乳化术并顺利植入球面Softec或者非球面Ocuva人工晶状体。术前和术后第3mo使用VISX Wavescan像差计进行像差测量与比较。结果：两组间统计学无显著性差异。术后的高阶像差均方根值（root-mean-square,RMS）：Softec组0.27±0.11,Ocuva组0.28±0.13,球面像差（spherical aberration,SA）：Softec组0.11±0.07,Ocuva组0.11±0.08。结论：与球面Softec人工晶状体比较,Ocuva非球面人工晶状体似乎没有减少术后高阶像差的优势。     

Comparison of pseudophakic visual quality in spherical and aspherical intraocular lenses

Objective: This study compares the visual performance of spherical and aspherical intraocular lenses (lOLs) by measuring higher-order aberration and contrast sensitivity (CS) values.Design: Prospective controlled study.Participants: Fifty-seven patients with age-related cataract (61 eyes).Methods: Patients were randomly allocated to 1 of 3 groups and implanted with either aspherical IOLs, Acrysof IQ (SN60WF) or Tecnis Z9001, or a spherical IOL, Acrysof Natural. Patients underwent routine examinations, including visual acuity, slit-lamp checks, and best-corrected visual acuity (BCVA), as well as measurement of higher-order aberrations and CS values, preoperatively and at 1 week, 1 month, and 2 months postoperatively.Results: All the patients had a BCVA better than 20/30 postoperatively. The spherical aberrations of the IQ group and Tecnis group were both lower than in the Natural (control) group (IQ: p <Tecnis: p < 0.05); there was no significant difference in coma and higher-order aberration. No statistically significant difference was found in spherical aberration, coma, or higher-order aberration between the IQ and Tecnis groups. Under glare conditions, the CS values of the 2 aspherical IOLs were obviously better (IQ: p < 0.05; Tecnis: p < 0.05) than the CS value of the spherical IOL group at low frequency (IQ: 6.3°, Tecnis: 4.0°); under non-glare conditions there was a significant difference in CS values between the aspherical IOL groups and the control group (IQ: p <Tecnis: p < 0.01) at low frequency (both 6.3°). There was no statistical difference between the IQ and the Tecnis groups with or without glare.Conclusions: An aspherical IOL can effectively reduce spherical aberration after cataract surgery, enhance CS values, and improve visual quality compared with traditional spherical IOLs for age-related cataract. However, there was no statistically significant difference in postoperative aberration and CS values between the Acrysof IQ and Tecnis Z9001 aspherical IOLs.     

个性化植入非球面人工晶状体术后视觉质量的临床观察

目的 观察根据患者角膜球差植入不同球差的非球面人工晶状体术后患者的视觉质量.方法 选择年龄相关性白内障患者62例(62眼)行白内障超声乳化吸出联合人工晶状体植入术,随机分为试验组及对照组,其中试验组32例(32眼)术前根据角膜球差植入非球面人工晶状体,对照组30例(30眼)随机植入非球面人工晶状体.术后3个月进行两组患者的视力、角膜球差、对比敏感度检查和生活问卷调查.结果 术后3个月,患者裸眼视力为4.89±0.57,与术前的4.00±0.31相比,差异有统计学意义(P=0.00),其中试验组裸眼视力为4.91±0.02,对照组为4.89±0.37,差异无统计学意义(P=0.48);最佳矫正视力试验组和对照组分别为4.97±0.21和4.97±0.18,差异亦无统计学意义(P=0.91);两组总角膜球差术后为(0.271±0.222) μm,与术前的(0.262±0.213) μm相比差异无统计学意义(P=0.47);对比敏感度检查在暗光及暗眩光状态下1.5c·d-1、3.0c·d-1、6.0c·d-1、12.0 c·d-、18.0c·d-1 15个不同空间频率下试验组均显著高于对照组(均为P＜0.05),在明光及明眩光状态5个空间频率下对比敏感度两组间差异均无统计学意义(均为P＞0.05);术后不良视觉症状发生率试验组少于对照组,患者满意度好于对照组(均为P＜0.05).结论 根据角膜球差植入非球面人工晶状体,术后均能够获得较满意的视觉质量,为个性化植入非球面人工晶状体这一方法的可行性提供了临床依据.     

Comparison of clinical outcomes between iris-fixated anterior chamber intraocular lenses and scleral-fixated posterior chamber intraocular lenses in Marfan syndrome with lens subluxation

Background: To compare the clinical outcomes in Marfan's with subluxated lens having phaco‐emulsification with simultaneous scleral‐fixated posterior chamber intraocular lens or iris‐fixated anterior chamber intraocular lens implantation. Design: Randomized case series in the State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat‐sen University, Guangzhou, China. Participants: Seventy‐one eyes of 49 patients with Marfan syndrome with subluxated lens. Methods: This is a randomized case series of patients with Marfan syndrome and subluxated lenses who underwent phaco‐emulsification combined with scleral‐fixated posterior chamber intraocular lens or iris‐fixated anterior chamber intraocular lens implantation. Main Outcome Measures: The evaluation indexes included the surgery time, best corrected visual acuity, intraocular pressure, aqueous flare and cells counts, corneal endothelium counts and complications. Results: Increase in best corrected visual acuity in both groups was not significant. The aqueous flare and cells rose in both groups postoperatively. Significant difference between the two groups at 1 week postoperatively was found, whereas no statistically significant difference was found later. The loss rate of corneal endothelium cells in the scleral‐fixated posterior chamber intraocular lens group was 13.2% and 19.5% at 3 months and 1 year postoperatively, which in the iris‐fixated anterior chamber intraocular lens group was 13.3% and 19.3% (P > 0.05). Prolapse of vitreous was found in 21 cases intraoperatively. The posterior capsule opacification rate was 32% and 15%, respectively. The decentration of the intraocular lens was found in 19 eyes (48.7%) in the scleral‐fixated posterior chamber intraocular lens group 1 year postoperatively, whereas none was found in the iris‐fixated anterior chamber intraocular lens group. Conclusions: Iris‐fixated anterior chamber intraocular lens after phaco‐emulsification presented a safe, simple and efficient approach for managing subluxated lens in Marfan syndrome.     

AcrySof IQ Toric人工晶状体植入矫正角膜散光的疗效

目的：评价白内障手术中植入AcrySof IQ Toric散光型人工晶状体矫正角膜散光的效果及人工晶状体在囊袋内的稳定性。

方法：对21例26眼伴有角膜规则散光的白内障患者,植入AcrySof IQ Toric散光型人工晶状体,观察术前及术后裸眼视力、最佳矫正视力; 术前角膜散光、预计散光、总散光,术后角膜散光及残余散光; 以及术后人工晶状体旋转度。

结果：术后所有患者裸眼视力及最佳矫正视力均明显提高; 术后残留散光0.55±0.33D,与术前总散光2.05±0.57D相比明显下降(t=13.574,P<0.05); 与术前预留散光0.47±0.19D比较无统计学意义(t=1.149,P>0.05)。术后3mo角膜散光-1.89±0.53D,与术前角膜散光2.01±0.58D相比无差异(t=1.908,P>0.05); 所有26眼的人工晶状体旋转度均<20°,平均旋转为(3.65±2.86)度。

结论：白内障超声乳化吸除联合AcrySof IQ Toric IOL植入矫正散光手术,能够有效的减少患者的散光,术后IOL旋转稳定性良好,是治疗白内障合并散光患者的有效的手术方法。     

非球面人工晶状体植入术后视觉质量评价

目的 评价非球面设计的人工晶状体AcrySof(R) IQ对提高老年性白内障患者术后视功能的作用.方法 采用同期临床对照研究,超声乳化白内障吸出联合人工晶状体植入术后的老年性白内障患者132例(160眼),其中植入AcrySof(R) IQ IOL 60例76眼,为IQ组;植入AcrySof(R) Natural 72例84眼,为Natural 组.观察患者的术后视力、对比敏感度和眩光敏感度、球差和并发症,问卷调查患者不良视觉症状和满意度.结果 术后3个月,IQ组裸眼视力(uncorrected visual acuity,UCVA)为4.92±0.10,最佳矫正视力(best corrected visual acuity,BCVA)为5.02±0.10; Natural组UCVA为4.89±0.12, BCVA为5.00±0.09;差异均无统计学意义(P＞0.05).低、中、高各频段对比敏感度和眩光敏感度 IQ组为47.44±10.95、27.72±6.69、7.62±2.04和40.61±10.48、22.73±6.88、6.38±1.22;Natural组为31.55±6.68、24.67±5.49、6.17±1.43、27.27±5.78、17.62±3.90、4.83±0.82,差异有统计学意义(P＜0.01).球差IQ组为(0.09±0.04)μm,Natural组为(0.52±0.17)μm,差异有统计学意义(t=22.15,P=0.000).问卷结果 显示IQ组较Natural组术后眩光、光晕的发生率低,患者满意度高.结论 非球面人工晶状体AcrySof(R)IQ在一定程度上平衡了角膜的正球差,减少了人工晶状体眼的球差,提高了对比敏感度和眩光敏感度,改善了视觉质量,获得了患者满意的效果.     

Contralateral comparison of visual outcome of AcrySof IQ and SA60AT intraocular lenses

Objective: To compare the visual performance of aspherical AcrySof IQ (SN60WF) and SA60AT spherical intraocular lenses after cataract surgery. Design: Prospective comparative study.Participants: Seventy eyes of 35 patients who underwent phacoemulsification for cataract surgery.Methods: The IQ lens was implanted in one eye and the SA60AT lens in the other eye of every patient. Refraction, uncorrected visual acuity (UCVA), and best spectacle-corrected visual acuity (BSCVA) were measured 1 and 3 months after surgery. At 3 months’ follow-up, the quality of vision, in terms of contrast sensitivity (CS) with and without glare and higher-order aberrations (HOA), was also determined.Results: At 3 months postoperative, the mean UCVA in the IQ and SA60AT groups was 0.25 (SD 0.26) and 0.30 (SD 0.27), respectively, and BSCVA was 0.10 (SD 0.16) in both groups. Spherical refractive error was -0.56 (SD 1.03) D and -0.47 (SD 0.64) D in the IQ and SA groups, respectively. In photopic conditions without glare, IQ eyes had statistically significant better CS at 12 cycles per degree (cpd) and better function at 3 and 18 cpd, and in mesopic conditions without glare, IQ eyes also had better results at 3, 12, and 18 cpd. In mesopic conditions with glare, IQ eyes also had better CS in 6 and 18 cpd. In terms of aberrations, the IQ group had significantly (p < 0.05) lower spherical aberrations, root mean-square, and coma X and Y values with 6 mm pupil size than the SA group.Conclusions: In terms of refraction, no significant difference was found between these 2 types, but there was a difference in the quality of vision in photopic and mesopic conditions and also HOA. Those with reactive and dilated pupils, such as younger patients and night drivers, may be more satisfied with IQ aspherical lenses.     

Comparison of clinical outcomes with three different aspheric intraocular lenses

Acta Ophthalmol. 2011: 89: 40–46

Abstract.

Purpose: To compare the quality of vision achieved with different aspheric intraocular lens (IOL) implants. Methods: This prospective, comparative and randomized study included 90 eyes that underwent phacoemulsification and implantation with one of three different aspheric IOLs. Patients were assigned randomly to receive one type of aspheric IOL: Tecnis Z9003^® (Advanced Medical Optics, Santa Ana, California, USA) (Group A), Acrysof IQ SN60WF^® (Alcon Laboratories, Fort Worth, Texas, USA) (Group B) or Akreos ADAPT‐AO^® (Bausch & Lomb, Rochester, New York, USA) (Group C). Ophthalmic examinations, including uncorrected visual acuity, best spectacle‐corrected visual acuity (BCVA), refractive error, wavefront analysis, contrast sensitivity under mesopic and photopic conditions, and a subjective questionnaire, were performed postoperatively. Results: The mean BCVA, mean refractive error and high‐order aberrations were not significantly different among the three groups. The spherical aberrations were 0.0021 ± 0.096 for group A, 0.048 ± 0.071 for group B and 0.11 ± 0.089 for group C, indicating a significantly lower magnitude in group A (p = 0.012). In addition, group A showed significantly better results in contrast sensitivity under mesopic (p = 0.042) and photopic (p = 0.047, 0.049) conditions at low spatial frequencies. Nevertheless, postoperative patient satisfaction was not different among the three groups. Conclusion: The Tecnis Z9003^® IOL reduced spherical aberrations and improved contrast sensitivity under mesopic and photopic conditions at low spatial frequencies. Nevertheless, the final visual quality was not different among the three groups.     

如何理解和选择非球面人工晶状体

非球面人工晶状体比传统的球面人工晶状体可提供更好的视觉质量，但它并非适合每位患者。可以选用不同球差的人工晶状体来抵消患者自身角膜的球差，术后获得零球差或者＋0．10lμm球差。必须注意的是，植入负球差的人工晶状体时，一定要使人工晶状体居于视轴的中心，尽量减少偏心。     

非球面晶状体与传统球面晶状体植入术后对比敏感度的研究

目的:比较白内障术后早期非球面晶状体与传统球面晶状体植入术后功能视力.方法:白内障患者共50例,随机分成两组,一组患者植入以Acrysof IQ(Alcon)为代表的非球面晶状体,共23例 23眼;一组植入以AR40e(AMO)为代表的传统球面晶状体,共27例27眼.于术后1mo用CSV-1000E对比敏感度测试仪(由VECTOR VISION 公司提供)进行对比敏感度测定.结果:以Acrysof IQ (Alcon)为代表的非球面晶状体在6.12.18cpd时较以AR40e(AMO)为代表的传统球面晶状体能显著的提高患者对比敏感度.结论:以Acrysof IQ(Alcon)为代表的非球面晶状体可提高患者的功能视力