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1.

Objective

To assess the diagnostic accuracy of diffusion weighted imaging (DWI-MRI) being a non-contrast based MR sequence versus dynamic contrast enhanced MRI (DCE-MRI) in the preoperative loco-regional staging of the cervical carcinoma.

Methodology

Fifty cases of proved cancer cervix prior staging subjected to dynamic post contrast technique: one pre-and six post contrast phases (40?s each). DWI was scanned using different b values and ADC values were measured.

Results

DWI was the most accurate in staging operable cases (93.3%).Parametrial infiltration was overestimated in 3 cases versus 4 cases in DCE-MR. DWI showed 100% sensitivity, positive predictive value and accuracy in the assessment of locally advanced carcinomas. In metastatic lymph nodes, DCE-MR showed the least accuracy of 86%.

Conclusion

DWI is helpful in discriminating local from locally advanced cervical carcinomas. DCE-MR can delineate cervical carcinomas confined to the uterus and exclude bladder/rectal invasion.  相似文献   

2.

Background

Urinary tract injuries occur in 3–10% of abdominal trauma. Early recognition and diagnosis of ruptured bladder is essential to lower this mortality rate. CT is the method of choice for the evaluation of patients with blunt or penetrating abdominal and/or pelvic trauma. Imaging in patients with suspected bladder injury with CT cystography may be performed using either an intravenous or retrograde technique.

Aim of work

The aim was to evaluate the role of CT in diagnosing traumatic urinary bladder injuries.

Materials and methods

The study was carried out on 32 patients with suspected traumatic urinary bladder injury. All patients were subjected to contrast-enhanced CT study and classified according to Sandler et al. classification of urinary bladder injuries.

Results

All patients were classified according to the type of the encountered urinary bladder trauma. Type I injury was diagnosed in 3.1% of patients, type II in 18.8%, type III in 3.1%, type IVa in 12.5%, type IVb in 43.7% and type V in 18.8%. 21.8% of patients were managed conservatively, while 78.2% of patients underwent surgical repair.

Conclusion

CECT well demonstrated traumatic urinary bladder injuries.  相似文献   

3.

Aim of the work

To evaluate the role of diffusion weighted imaging (DWI) in the planning for CT guided biopsy of lung and mediastinal lesions.

Subjects and methods

This cross sectional study included 23 patients with mean age was 42.7?years came with clinical and imaging suspicion of chest malignancy, referred for CT guided transthoracic biopsy. DWI and apparent diffusion coefficient (ADC) were evaluated for all patients to choose the area of maximum restriction.

Results

The study showed that with DWI guidance; all the biopsy specimens were diagnostic and provide adequate material for analysis.

Conclusion

DWI and measurement of ADC value has a very helpful role in the pre-procedural planning of transthoracic biopsies.  相似文献   

4.

Purpose

To highlight the relationship between coraco-humeral distance and subscapularis tendon tear.

Material and methods

Sixty-two shoulder MRI studies were examined. Twenty-two patients had partial or complete tear of subscapularis tendon and forty shoulder as a control group. Axial and oblique sagittal MR images were examined to measure the coraco-humeral distance followed by statistical analysis to correlate the distance with tendon tear.

Results

A cut-off value of 8.25?mm for the coraco-humeral distance gave a sensitivity of 77.5% and specificity of 72.7% for subscapularis tendon tear.

Conclusion

There is a well-known relationship between the coraco-humeral distance and the subscapularis tendon tear and its meticulous assessment in subjects with pain in the anterior shoulder region increases the diagnosis of subcoracoid impingement.  相似文献   

5.

Objectives

To assess diagnostic benefits of filling of the rectum with ultrasound gel during MR assessment of rectal cancer and the pitfalls that occurs due to rectal distention.

Materials/methods

40 patients presented with rectal cancer for either initial MR staging or for assessment after neoadjuvent chemoradiotherapy using ultrasound transmission gel as a contrast for rectal filling.

Results

MR with gel rectal filling showed better depiction in all patients with small tumors than in non filling of the rectum. The filling of rectum with gel increased the distance of the lower tumor border from the anal verge however it showed better assessment of the site of the fixed tumor lower edge in all cases of pedunculated tumor masses. Also rectal filling decreases the distance from the perirectal fascia which may affect the CRM.

Conclusions

MR with rectal gel filling is useful in assessment of cases with rectal cancer and by combining empty rectum & distended rectum in the same study we can get the benefits & avoid the pitfalls by correlating the images in both techniques.Clinical Relevance/Application This study helped in assessment of patients with rectal cancer either referred for initial MR staging or for assessment after neoadjuvent chemoradiotherapy.  相似文献   

6.

Purpose

To compare patient experience of whole-body MRI and FDG-PET/CT performed for lymphoma staging.

Methods

One-hundred-fifteen patients (59 males, 56 females; 53 Hodgkin, 62 non-Hodgkin; mean age: 43.8?years) with lymphoma underwent whole-body MRI and FDG-PET/CT for staging and filled a questionnaire regarding their experience of the examinations using a 4-point Likert scale (1, very good; 4,very bad). Differences were evaluated using Wilcoxon signed-rank test. Patients were asked to express their preference on both techniques. Preferences were compared on the basis of gender, age, and Ann Arbor stage using the chi-square test. A p-value?≤?.05 was considered significant.

Results

Most patients found FDG-PET/CT a more burdensome examination than whole-body MRI. Whole-body MRI received a significantly lower score regarding overall satisfaction (p?<?.05), patient experience before (p?<?.05) and after (p?<?.05) scan. No significant difference was found in scan preparation (p?=?.207) and patient experience during scan (p?=?.38). The average Likert scores were?<2 in all criteria for both types of scan. 54 patients preferred whole-body MRI, 10 preferred FDG-PET/CT, and 51 had no preference. There was no significant difference in technique preference according to gender (p?=?.73), age (p?=?.43), and stage (p?=?1.00).

Conclusions

Whole-body MRI and FDG-PET/CT demonstrate high degree of patients’ acceptance and tolerance.  相似文献   

7.

Objective

The aim of this study was to highlight the role of MRI in detecting and diagnosing trigeminal nerve neoplastic lesions.

Patients and methods

56 patients included in our study presented with trigeminal symptoms with or without other neurological symptoms, subjected to conventional MRI sequences and 3D sequences as (CISS) and T1 magnetization-prepared rapid acquisition gradient echo (MP-RAGE). The inclusion criteria included patients with intracranial neoplastic lesions involving the trigeminal nerve and/or its branches.

Results

28 patients met our inclusions criteria and subjected to statistical analysis; 19 patients were females and 9 were males ranging between 15 and 70?years with a mean age of 47.5?years. 14 lesions were benign and 14 were malignant, and were distributed according to final diagnosis as meningiomas (10 cases), lymphoma (6 cases), deposits (4 cases), nasopharyngeal carcinoma (4 cases) schwannoma (3 cases), and neurofibroma (one case). The most frequent involved segments of the trigeminal nerve was simultaneous involvement of both Meckel’s cave and cavernous sinus in nine cases (32%).

Conclusions

MRI is very helpful in demonstrating the whole intra-cranial course of the trigeminal nerve and in diagnosing various neoplastic lesions involving the nerve, and thus providing full roadmap before management.  相似文献   

8.

Background

Ninety percent of hepatic cancers are hepatocellular carcinomas (HCC) which have an unfavorable prognosis. HCC is a hypervascular tumor supplied mainly by the hepatic artery. It has a higher blood supply than the surrounding hepatic tissue due to neovascularization. Computed tomography with perfusion imaging (CTP) is a non invasive tool which quantifies the blood flow parameters of HCC and compares it to the surrounding tissue.

Purpose

To prove that CTP is a valuable diagnostic tool in diagnosis of HCC and posttherapeutic assessment.

Patients and methods

One hundred and twenty-six HCC patients with 150 focal lesions are enrolled this study. Perfusion parameters are quantified and results are compared to those of triphasic CT.

Results

CTP detected 141 lesions with 94% sensitivity and 40% specificity with elevated arterial perfusion (AP) and perfusion index (PI) with low portal flow (PF). It missed 5 lesions because of their hypovascularity and 4 lesions following radiofrequency ablation (RFA) and trans arterial chemo embolization (TACE).

Conclusion

CTP is a safe and specific imaging tool for diagnosis and assessment of therapeutic interventional procedures in HCC.  相似文献   

9.
Perianal fistula is a common disorder with high tendency to recur in spite of satisfactory surgery. Pelvic MRI is the preferable imaging modality for recognition and assessment of perianal fistulas.

Aim of the work

To evaluate the effectiveness of MRI in grading of primary perianal fistula and verification of its associated findings in correlation with surgical outcome.

Subjects and methods

This prospective study included 30 patients with age range 14–44 years. Preoperative MR grading was correlated with surgical outcome.

Results

The sensitivity, specificity, PPV, NPV and weighted Kappa of MR grading in correlation with surgery was 95.8%, 83.3%, 95.8%, 83.3% and 0.79 respectively with P value = 0.000

Conclusion

MRI is a valuable modality for grading of primary perianal fistula and its complications. Accurate pre-operative grading may reduce the surgical complications and possibility of recurrence.  相似文献   

10.

Background

Lateral epicondylitis is referred to a degenerative disorder that affects the common extensor tendon (CET) where it attaches to the lateral epicondyle of the humerus. Nowadays, one of minimally invasive interventions is platelet-rich plasma (PRP) injection that had been explored in some controlled clinical studies to show its effectiveness in treating lateral epicondylitis through inducing inflammation rather than suppressing it.

Objectives

The aim of our study was to investigate the effectiveness of ultrasound guided platelet-rich plasma (PRP) injection in treating chronic lateral epicondylitis in addition to identifying the potential sonographic morphological changes in the common extensor tendon (CET) after PRP injection.

Results

Statistical analysis showed high significant improvement in all ultrasound findings of common extensor tendon (CET) including echotexture, thickness, cross section, partial tear and calcification in majority of patients.

Conclusion

We concluded that US-guided platelet-rich plasma (PRP) injection for treatment of lateral epicondylitis was a safe, minimally invasive and effective procedure in improving the sonographic and pathological changes of common extensor tendon (CET).  相似文献   

11.

Background

The ankle is frequently injured in trauma, overuse syndrome and inflammatory processes. Different imaging modalities assess the ankle, including plain radiography, computed tomography (CT), magnetic resonance imaging (MRI), and ultrasonography (US).

Purpose

Our objective is to assess the role of high resolution US as a valuable tool in the depiction of causes of ankle joint pain.

Patients and methods

The study included 28 patients presented with ankle pain ranging in age from 17 to 60 years. They were examined by US and findings were correlated with MRI.

Results

US was capable to detect various lesions (synovitis, arthritis, plantar fasciitis, tendon and ligamentous lesions). It had a sensitivity of 95.4%, a specificity of 83.3% and an overall accuracy of 92.8%. US had a limited value in detection of avascular necrosis (AVN), bone marrow oedema and fractures.

Conclusion

US can be used as a first step diagnostic tool in cases of ankle pain. MRI should be spared to cases with negative or equivocal US findings.  相似文献   

12.

Purpose

to assess the efficacy of FDG PET/CT in detecting unexpected additional primary malignant neoplasms in patients being evaluated by PET/CT for known malignancies compared to conventional staging work-up (CSW).

Patients and methods

Of 1889 patients referred for whole-body FDG PET/CT in the period from February 2015 to May 2016, only 273 were included in this prospective study. Patients included are those with histopathologicaly proven primary malignancy and sent for initial tumor staging before treatment within 1 month of CSW that was performed for the patients according to the site and cell type of the primary tumor. Histopathologic examination was performed for lesions indicating additional primary cancer detected by either PET/CT or CSW.

Results

In 13 out of 273 patients included in the study (4.76%) only were proved to have additional primary cancer, the PPV of PET/CT for detecting an additional primary cancer was 56.5%. Also, it showed high sensitivity of 89.2%, which was significantly higher than 23% from the CSW (P < 0.005).

Conclusion

PET/CT is more accurate than CSW for detecting additional primary cancer with a higher sensitivity and positive predictive value, which consequently affect further management.  相似文献   

13.

Objective

The prognosis of different histologic subtypes of RCC varies and affects management. Patients with chromophobe or papillary RCC have better prognosis than those with clear cell RCC. The aim of our work was to study the utility of DCE and DWI in the preoperative prediction of renal cell carcinoma subtypes, using histopathology as a gold standard method of diagnosis.

Patients and methods

Thirty five patients with 38 renal masses were included in the study. All had DCE MRI studies with DWI sequences, CER and ADC values calculation for normal and diseased renal tissues.

Results

The Mean ADC value of normal renal parenchyma was significantly higher than RCC. The CER and ADC values for Clear cell RCC were higher than Papillary and Chromophobe RCC. No statistically significant difference was found between the CER & ADC values for Papillary and Chromophobe RCC. CER & ADC values of clear RCC were higher than non clear RCC.

Conclusions

DCE MRI in addition to DWI & ADC appears as a very helpful imaging tool in the differentiation between clear cell and non-clear cell RCCs.  相似文献   

14.

Aim

The aim of this study is to evaluate the role of high resolution ultrasonography (HRUS) of the hip in premature neonates admitted to the neonatal intensive care unit (NICU) in diagnosis of septic hip arthritis.

Patients and methods

This prospective study was done for twenty premature neonates having clinical and laboratory findings compatible with the diagnosis of acute septic arthritis. They were subjected to HRUS of the hip as well as US-guided aspiration and analysis of synovial fluid.

Results

Hip ultrasonography showed synovial fluid containing echoes in twelve patients and was clear in six patients. Joint capsule was thickened in fourteen patients. Seventeen patients had sonographic features of septic arthritis. The sensitivity of HRUS was 93.8%, specificity 50%, positive predictive value 88.2%, negative predictive value 66.7% and the accuracy was 85%.

Conclusion

HRUS is beneficial in early diagnosis of septic hip arthritis in premature neonates admitted to the NICU. It is an easy, available and rapid procedure.  相似文献   

15.

Purpose

To estimate the accuracy of 18FDG PET/CT in detection of recurrent cancer ovary and to describe the localization of metastases for restaging.

Materials and methods

44 female patients with suspicion of ovarian cancer recurrence underwent a PET/CT scan from September 2013 to August 2015.

Results

CA-125 levels were elevated in 36 patients, 25 patients presented with alterations on imaging and 18 patients had clinical suspicion of recurrence. Imaging examinations were normal in 10/36 patients with elevated CA-125. 18FDG PET/CT scan was positive in 39/44 patients, and it was negative in 5/44 patients, 4/5 patients continued to be disease free all over the follow-up (true negative), while PET-CT missed recurrence in 1/5 patient (false negative). 1/39 patient was false positive. Sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of integrated PET/CT were calculated to be 91%, 76%, 96%, 50% and 87%.

Conclusion

18FDG PET/CT is an accurate modality for detection of recurrence of ovarian cancer. The accuracy of PET–CT in precise localization of suspicious FDG uptake can lead to proper assessment of disease recurrence, thus allow for restaging of the disease and subsequently optimizing treatment plan for these patients.  相似文献   

16.

Objective

The goal of this study was to highlight the role of follow up CT angiography examination in detection and classification of endoleaks and therefore deciding management plans after endovascular abdominal aortic aneurysm repair (EVAR).

Patients and Methods

During one year duration 37 patients who have been operated were examined 1 and 6 months after EVAR as routine follow up. The images obtained were interpreted and reconstructed using dedicated software and work stations.

Results

Out of 37 cases, 14 cases (37.8%) had positive endoleaks and 23 cases (62.2%) were free. Type I endoleak was diagnosed in 4 cases (10.8%) and type II endoleaks was diagnosed in 10 cases (27%) as 7 cases (18.9%) showed leak through lumbar arteries and 3 cases (8.1%) showed leak through the inferior mesenteric arteries.

Conclusion

CT angiography can accurately detect and classify endoleaks and thus determine line of treatment. Endoleaks are often asymptomatic and may become evident intra operatively or many years after the operation, therefore lifelong imaging supervision is necessary.  相似文献   

17.

Introduction

Radiographic findings of the shoulder joint have been reported in patients with rotator cuff tear, greater tuberosity changes are among the most reported.The aim of this work is to assess the greater tuberosity sclerosis as a radiographic sign of rotator cuff tear and its relation to the tear size.

Patients and methods

This study was conducted from July 2009 until May 2013 in a retrospective fashion and included 425 patients, 250 females (58.8%) and 175 males (41.2%).

Results

Sclerosis was detected in 398 cases out of 425 patients (93.6%). Of those, 360 (90%) were found to have a tear of the rotator cuff documented on M.R.I. Also greater tuberosity sclerosis being more prominent with large-sized tears. One hundred (23.5%) patients had been operated arthroscopically and a tear documented intraoperatively (Table 2).

Conclusion

Greater tuberosity sclerosis has both high sensitivity and positive predictive value for rotator cuff tear. Also greater tuberosity sclerosis is found more with large-sized rotator cuff tears.  相似文献   

18.

Purpose

To evaluate the role of 3-dimensional (3DUS) and 4-dimensional ultrasound (4DUS) in detection of fetal causes of oligohydraminos.

Patients and methods

250 pregnant females (Age range from 19 to 45?years, mean age 33?years) were referred from the Obstetrics and Gynecology Department with oligohydraminos for fetal anomaly scan and Doppler study.

Results

111 of the 250 patients were primi- gravida and 139 were multigravida. Consanguinity was positive in 106 females. In 100 patients, the examined fetuses were abnormal, TORCH infection was +ve in 25 patients. In 150 cases no fetal cause was detected for oligohydraminos. Autosomal recessive polycystic kidney disease (ARPKD, Potter type I) was the commonest fetal cause in our group detected in 24 of 100 patients followed by bilateral multicystic dysplastic kidney (Potter type II) in 19 patients, unilateral renal aplasia was the least cause in our study.

Conclusion

3-dimensional and 4-imensional ultrasound and anomaly scan are effective in detecting fetal causes of oligohydraminos and early determination of lethal causes.  相似文献   

19.

Objective

To compare the accuracy of 2D and 3D CT measurements of femoral anteversion angle, in pediatric patients with developmental hip dysplasia.

Materials and methods

Twenty patients (20 hips) with unilateral non syndromic DDH were studies. CT scans were performed using a 16 slice CT scanner to measure the femoral anteversion angle (FAVA) using 2D & 3D techniques. Findings were correlated with the intra operative measurements.

Results

There was a significant difference between 2D & 3D methods. Results of clinical assessment were comparable to results of 3D CT assessment which range from 30 to 50° with a mean of 37.5°. Mean percent difference between 3D and intra operative measurement of FAVA was significantly lower than the corresponding value between 2D and intraoperative measurement of FAVA.

Conclusion

3D is more accurate than 2D in measuring the degree of FAVA in DDH patients. It is easily applied and rapid and doesn't require sophisticated software.  相似文献   

20.

Background

The knee menisci are compound anatomical structures with important purposes within the knee. In the long term, meniscal losing results in high risk of developing degenerative osteoarthritis. MRI is an accurate and non-invasive diagnostic method for the knee injuries providing satisfactory guide for conservative treatment and guarding the patients from uncritical arthroscopy.

Objective

This study aimed to detect the MRI accuracy in diagnosis of meniscal lesions compared to arthroscopy.

Patients & methods

This study included 13 females and 17 males presented by pain, swelling, limitation of movement, in the duration from April 2015 to June 2016. All patients were subjected to MRI followed by arthroscopy.

Results

The study revealed that specificity, sensitivity, NPV, PPV and accuracy, in MRI diagnosis of medial meniscal abnormal signals were 50%, 95.8%, 88.4%, 86.6%, and 90% respectively, whereas those for lateral meniscus signals were 84.6% 88.2%, 84.6%, 88.2% and 86.7% respectively.

Conclusion

MRI of the knee will give the orthopedic surgeons ability to select suitable treatment and arthroscopic interference for their patients. MRI has high accuracy in meniscal tears diagnosis allowing accurate grading of them.  相似文献   

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