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1.
Revision of Failed Laparoscopic Adjustable Gastric Banding to Roux-en-Y Gastric Bypass 总被引:3,自引:3,他引:0
Background: The most common bariatric surgical operation in Europe, laparoscopic adjustable gastric banding (LAGB), is reported
to have a high incidence of long-term complications. Also, insufficient weight loss is reported. We investigated whether revision
to Roux-en-Y gastric bypass (RYGBP) is a safe and effective therapy for failed LAGB and for further weight loss. Methods:
From Jan 1999 to May 2004, 613 patients underwent LAGB. Of these, 47 underwent later revisional Roux-en-Y gastric bypass (RYGBP).
Using a prospectively collected database, we analyzed these revisions. All procedures were done by two surgeons with extensive
experience in bariatric surgery. Results: All patients were treated with laparoscopic (n=26) or open (n=21) RYGBP after failed
LAGB. Total follow-up after LAGB was 5.5±2.0 years. For the RYGBP, mean operating time was 161±53 minutes, estimated blood
loss was 219±329 ml, and hospital stay was 6.7±4.5 days. There has been no mortality. Early complications occurred in 17%.
There was only one late complication (2%) – a ventral hernia. The mean BMI prior to any form of bariatric surgery was 49.2±9.3
kg/m2, and decreased to 45.8±8.9 kg/m2 after LAGB and was again reduced to 37.7±8.7 kg/m2 after RYGBP within our follow-up period. Conclusion: Conversion of LAGB to RYGBP is effective to treat complications of LAGB
and to further reduce the weight to healthier levels in morbidly obese patients. 相似文献
2.
Biliopancreatic Diversion with Duodenal Switch Combined with Laparoscopic Adjustable Gastric Banding
Gabriel SG Karaindros CA Papaioannou MA Tassioulis AA Gabriel SG Sigalas VI Giannakakis PP 《Obesity surgery》2005,15(4):517-522
Background: The authors investigated the usefulness of an approach combining biliopancreatic diversion (BPD) with duodenal
switch (DS) and laparoscopic adjustable gastric banding (LAGB) in morbidly obese patients. Methods: 258 morbidly obese patients
underwent bariatric surgery. 80 underwent gastric bypass (GBP), with an 80-ml pouch, a 120-150-cm common channel and a 350-cm
alimentary limb (Group 1). 178 underwent BPD combined with DS-LAGB (Group 2): an 80cm common channel and a 200-cm alimentary limb were created in 68 patients (Subgroup 2a); a 120-cm common channel and a 300-cm alimentary limb were created in 110 patients (Subgroup 2b). Quality of life was assessed using the Moorehead-Ardelt Quality of Life Questionnaire (MA-QLQ). Results: At 2 years, mean
BMI and %EWL were 27.8 kg/m2 and 77.4 (Group 1), 25.2 kg/m2 and 99.6 (Subgroup 2a), and 27.6 kg/m2 and 79.3 (Subgroup 2b), respectively. 4 GBP patients regained their weight 2 years after surgery. There was 1 death, not
related to surgery in Subgroup 2b. Preoperative MA-QLQ scores were similar between groups; at 2 years, MA-QLQ scores were
higher in Subgroups 2a and 2b compared to Group 1 (+2.49 and +2.59 vs +0.98, respectively). Conclusion: Combination bariatric
surgery is a safe, effective and durable weight loss option for the treatment of morbid obesity. 相似文献
3.
Background: No study has surveyed the factors that influence morbidly obese patients' preference for a particular bariatric
operation. Method: 469 consecutive patients in 2 major bariatric surgery centers in the United States (US, 124) and Australia
(AU, 345) were prospectively studied to determine referral pattern and reason for their choice of operation. Results: The
predominant operation was laparoscopic adjustable gastric banding (LAGB) in both US (75%) and AU (83%) centers. Gender (70%
female), BMI (45 kg/m2 ) and age (42.5 years) were similar in both cohorts. In Australia, 53% had referral initiated by primary doctors and 25%
by another patient, while in the US, 43% by another patient and 27% by the Internet. Safety of the operation (43%) was the
highest-rated factor in choosing LAGB. LAGB being "least invasive" was most significant in the US (46%), and "surgical safety"
in Australia (45%). In the US, Rouxen-Y gastric bypass was preferred due to "lack of a foreign body" (31%) and "inability
to cheat" (28%), while in Australia, "dumping" was the most significant reason (50%). Duodenal switch (BPD/DS) was selected
in 11% of patients, primarily because of "durability of the weight loss" (51%). Surprisingly, only 1 patient in the US group
selected BPD/DS because the pylorus remains intact. Conclusion: Safety and invasiveness had the greatest impact on patient
choice for bariatric operation in two different countries. This information may help clinicians better understand their patients'
concerns, and their treatment choices. 相似文献
4.
Angrisani L Lorenzo M Borrelli V Giuffré M Fonderico C Capece G 《Obesity surgery》2006,16(9):1135-1137
Background: The use of the Bio-Enterics intra-gastric balloon (BIB) has been shown to be a safe and effective procedure for
the temporary treatment of morbid obesity. We conducted a retrospective comparative analysis of the weight loss in patients
that after BIB removal underwent bariatric surgery and those who did not wish surgery. Methods: From January 2000 to March
2004, 182 BIBs were positioned in 175 patients (104 F / 71 M; mean age 37.1±11.6 years, range 16-67; mean BMI 54.4 ± 8.1 kg/m2, range 39.8-79.5; mean %EW 160.8±32.9% range 89-264). Patients were excluded from this study who had emergency BIB removal
for balloon rupture (n=2, 1.1%) and for psychological intolerance (n=7, 7.8%). All patients were scheduled for a bariatric
operation, before BIB positioning. After BIB removal, a number of patients now declined surgery. Consequently, patients were
allocated into 2 groups: Group A in whom BIB removal was followed by bariatric surgery (Lap-Band?, laparoscopic gastric bypass, duodenal switch) (n=86); Group B patients who after BIB removal refused any surgical procedure
(n=82). Both groups were followed for a minimum of 12 months. Results were reported as mean BMI and %EWL ± SD. Statistical
analysis was done by Student t-test or Fisher's exact test, with P<0.05 considered significant. Results: Mean BMI and mean %EWL in the 166 patients at time of removal were 47.3 ± 8.1 kg/m2 and 32.1±16.6%, respectively. At the same time, mean BMI was 47.6±6.9 and 48.1±6.5 kg/m2 in group A and B (P=NS). At 12 months follow-up (100%), mean BMI was 35.1 kg/m2 in Group A (BIB + surgery) and 51.7 kg/m2 in Group B (BIB alone) (P<0.001). Conclusions: After BIB removal, half (49.4%) of the patients scheduled for surgery refused a bariatric operation.
These patients returned to their mean initial weight at 12 months follow-up. Therefore, bariatric surgery after BIB removal
is highly recommended. 相似文献
5.
Background: Bulimia nervosa (BN) is an eating disorder, characterized by consumption of huge amounts of food during discrete
periods. Unlike patients with binge-eating disorder (BED), patients with BN demonstrate elements of compensatory "purging"
behavior to prevent weight gain and obesity: i.e. self-induced vomiting, use of laxatives and enemas. These habits may prevent
patients from attaining morbid obesity (MO), but may seriously affect life-style and become an excruciating, sometimes life-threatening
condition. Methods: 6 of 108 patients (5.6%) who underwent BPD in our clinic (laparoscopic Scopinaro BPD - 1, open BPD/DS
- 4, Lap. BPD/DS - 1) suffered from BN preoperatively. Their preoperative weight was 68-117 kg and BMI 27.6-41.9 kg/m2. 4 of 6 patients had BMI <40 kg/m2 before BPD but were MO in the past. The patient with the lowest weight had repeated gastroesophageal bleeding during self-induced
vomiting. 3 of the 6 patients had previously failed intragastric balloon or Lap-Band?. Results: All 6 patients were cured or significantly improved of bulimic symptoms soon after BPD. Weight loss was very good
and never reached an undesirably low level. Patient satisfaction was high. Conclusion: Severe BN may be considered as a latent
and potentially malignant MO. BPD (or BPD/DS) may be an effective solution for some patients with severe BN, as a final decision
after unsuccessful organized conservative attempts. All candidates for bariatric surgery should be screened for BN, because
it may influence choice of procedure in favor to BPD or BPD/DS. 相似文献
6.
A Comparison of Laparoscopic Adjustable Gastric Banding and Biliopancreatic Diversion in Superobesity 总被引:5,自引:0,他引:5
Background: Controversy exists regarding the best surgical treatment for superobesity (BMI >50 kg/m2), and a comparison of the 2 most commonly performed procedures in Europe, namely biliopancreatic diversion (BPD) and laparoscopic
adjustable gastric banding (LAGB), has not yet been reported. Methods: BPD has been performed in 134 morbidly obese patients
since 1996, and as the primary bariatric procedure in 23 superobese patients. 23 sex-matched patients who most closely resembled
the age and BMI of the 23 BPD patients were chosen from 1,319 patients who had undergone LAGB since 1996. These groups were
compared using appropriate statistical tests. Results: BPD was performed laparoscopically in 12 patients. Median excess weight
loss at 24 months was 64.4% following BPD and 48.4% following LAGB. Hospital stay and complication rate were significantly
greater with BPD, although the majority of complications were related to the laparotomy wound in patients undergoing open
BPD. Rate of resolution of obstructive sleep apnea, hypertension and diabetes mellitus following LAGB was similar to BPD.
Conclusion: BPD results in significantly greater weight loss than LAGB in superobese patients, but is associated with a longer
hospital stay and a higher complication rate in patients undergoing open BPD. 相似文献
7.
Guy Slater F.R.C.S. Jennifer Duncombe M.B. B.S. George A. Fielding F.R.C.S. F.R.A.C.S. 《Surgery for obesity and related diseases》2005,1(6):96-579
BACKGROUND: Laparoscopic adjustable gastric banding (LAGB) fails in 5% of patients due to band-related complications or patient intolerance. A subset of patients subsequently managed with biliopancreatic diversion (BPD) have failed to achieve a percentage of excess weight loss (%EWL) > 50% or a body mass index (BMI) < 35 kg/m(2) even after a further procedure shortening the common channel to 30 cm. METHOD: A computerized obesity database was used to identify the study group and collect preoperative and outcome data. Patient outcomes were analyzed in 2 groups: LAGB removed either because of a failure to lose weight (FTLW) or because of a band-related complication (eg, recurrent gastric prolapse, gastric erosion, intractable dysphagia). RESULTS: A total of 2300 patients underwent LAGB between 1996 and 2003. LAGB failed in 95 (4%) of these patients, 79 of whom had subsequent BPD. Of these 79 patients, 8 (10%) failed to lose further weight and had their common channel shortened to 30 cm. Six patients were identified who, despite this revision surgery, still had a BMI > 35 kg/m(2) or %EWL < 50 and are considered failures. Two further patients failed to lose any weight after revision for what they saw as an unsatisfactory outcome. There was minimal evidence of malabsorption in these 8 patients, and 4 had slow intestinal transit down the alimentary limb of the BPD. CONCLUSION: The reasons for the failure of malabsorption and restrictive surgery in these patients appear to be physiological, not psychological. Uncontrolled hunger, particularly in the patients with FTLW, and an abnormally slow metabolism are likely to be important. 相似文献
8.
Weiner R Blanco-Engert R Weiner S Matkowitz R Schaefer L Pomhoff I 《Obesity surgery》2003,13(3):427-434
Background: Laparoscopic adjustable gastric banding (LAGB) has been our choice operation for morbid obesity since 1994. Despite
a long list of publications about the LAGB during recent years, the evidence with regard to long-term weight loss after LAGB
has been rather sparse. The outcome of the first 100 patients and the total number of 984 LAGB procedures were evaluated.
Methods: 984 consecutive patients (82.5% female) underwent LAGB. Initial body weight was 132.2 ± 23.9 SD kg and body mass
index (BMI) was 46.8 ± 7.2 kg/m2. Mean age was 37.9 (18-65). Retrogastric placement was performed in 577 patients up to June 1998. Thereafter, the pars flaccida
to perigastric (two-step technique) was used in the following 407 patients. Results: Mortality and conversion rates were 0.
Follow-up of the first 100 patients has been 97% and ranges in the following years between 95% and 100% (mean 97.2%). Median
follow-up of the first 100 patients who were available for follow-up was 98.9 months (8.24 years). Median follow-up of all
patients was 55.5 months (range 99-1). Early complications were 1 gastric perforation after previous hiatal surgery and 1
gastric slippage (band was removed). All complications were seen during the first 100 procedures. Late complications of the
first 100 cases included 17 slippages requiring reinterventions during the following years; total rate of slippage decreased
later to 3.7%. Mean excess weight loss was 59.3% after 8 years, if patients with band loss are excluded. BMI dropped from
46.8 to 32.3 kg/m2. 5 patients of the first 100 LAGB had the band removed, followed by weight gain; 3 of the 5 patients underwent laparoscopic
Roux-en-Y gastric bypass (LRYGBP) with successful weight loss after the redo-surgery. 14 patients were switched to a "banded"
LRYGBP and 2 patients to a LRYGBP during 2001-2002. The quality of life indices were still improved in 82% of the first 100
patients. The percentages of good and excellent results were at the highest level at 2 years after LAGB (92%). Conclusions:
LAGB is safe, with a lower complication rate than other bariatric operations. Reoperations can be performed laparoscopically
with low morbidity and short hospitalizations. The LAGB seems to be the basic bariatric procedure, which can be switched laparoscopically
to combined bariatric procedures if treatment fails. After the learning curve of the surgeon, results are markedly improved.
On the basis of 8 years long-term follow-up, it is an effective procedure. 相似文献
9.
Laparoscopic Bariatric Surgery in Super-obese Patients (BMI>50) is Safe and Effective: A Review of 332 Patients 总被引:2,自引:2,他引:0
Background: Bariatric surgery in super-obese patients (BMI >50 kg/m2) can be challenging because of difficulties in exposure of visceral fat, retracting the fatty liver, and strong torque applied
to instruments, as well as existing co-morbidities. Methods: A retrospective review of super-obese patients who underwent
laparoscopic adjustable gastric banding (LAGB n=192), Roux-en-Y gastric bypass (RYGBP n=97), and biliopancreatic diversion
with/without duodenal switch (BPD n= 43), was performed. 30day peri-operative morbidity and mortality were evaluated to determine
relative safety of the 3 operations. Results: From October 2000 through June 2004, 331 super-obese patients underwent laparoscopic
bariatric surgery, with mean BMI 55.3 kg/m2. Patients were aged 42 years (13-72), and 75% were female. When categorized by opertaion (LAGB, RYGBP, BPD), the mean age,
BMI and gender were comparable. 6 patients were converted to open (1.8%). LAGB had a 0.5%, RYGBP 2.1% and BPD 7.0% conversion
rate (P=0.02, all groups). Median operative time was 60 min for LAGB, 130 min for RYGBP and 255 min for BPD (P<0.001, all groups). Median length of stay was 24 hours for LAGB, 72 hours for RYGBP, and 96 hours for BPD (P <0.001). Mean %EWL for the LAGB was 35.3±12.6, 45.8±19.4, and 49.5±18.6 with follow-up of 87%, 76% and 72% at 1, 2 and 3
years, respectively. Mean %EWL for the RYGBP was 57.7±15.4, 54.7±21.2, and 56.8±21.1 with follow-up of 76%, 33% and 54% at
1, 2 and 3 years, respectively. Mean %EWL for the BPD was 60.6±15.9, 69.4±13.0 and 77.4±11.9 with follow-up of 79%, 43% and
47% at 1, 2 and 3 years, respectively. The difference in %EWL was significant at all time intervals between the LAGB and BPD
(P<0.004). However, there was no significant difference in %EWL between LAGB and RYGBP at 2 and 3 years. Overall perioperative
morbidity occurred in 27 patients (8.1%). LAGB had 4.7% morbidity rate, RYGBP 11.3%, and BPD 16.3% (P=0.02, all groups). There were no deaths. Conclusion: Laparoscopic bariatric surgery is safe in super-obese patients. LAGB,
the least invasive procedure, resulted in the lowest operative times, the lowest conversion rate, the shortest hospital stay
and the lowest morbidity in this high-risk cohort of patients. Rates of all parameters studied increased with increasing procedural
complexity. However, the difference in %EWL between RYGBP and LAGB at 2 and 3 years was not statistically significant. 相似文献
10.
Stroh C Hohmann U Remmler K Urban H Meyer F Lippert H Manger T 《Obesity surgery》2005,15(9):1347-1351
Rhabdomyolysis is an uncommon event in bariatric surgery. It can be caused by ischemia, crush injury, alcohol ingestion and
drug intake, and as a consequence renal failure can develop. A few reports indicate that patients undergoing bariatric surgical
intervention are at risk for rhabdomyolysis. A super-obese male (BMI 52 kg/m2) is reported, who underwent laparoscopic biliopancreatic diversion with duodenal switch (BPD/DS). Operative time was 265
minutes, and the BPD/DS operation was uneventful. Post-operatively, the patient complained of pain in both hips and the left
shoulder, and suffered oliguria. He was treated with fluids (isotonic saline), bicarbonate, and mannitol. Despite this, he
developed renal failure, which subsequently required hemodialysis. The patient died from arrhythmia and cardiac arrest on
the 8th postoperative day. Obese patients undergoing bariatric surgery are at risk of rhabdomyolysis. Prolonged compression
of the muscles during the surgical intervention, in long laparoscopic procedures, predisposes to this complication. 相似文献
11.
Laparoscopic Reoperative Sleeve Gastrectomy for Poor Weight Loss after Biliopancreatic Diversion with Duodenal Switch 总被引:13,自引:7,他引:6
Background: The revisional surgery for patients with inadequate weight loss after biliopancreatic diversion with duodenal
switch (BPD/DS) is controversial. It has not yet been determined whether a common channel should be shortened or gastric pouch
volume reduced. Since the revision of the distal anastomosis remains technically difficult and associated with possible complications,
we turned our attention to the reduction of gastric sleeve volume. This operation is more feasible and potential complications
are less probable. Patient and Method: We present the case of a 47-year-old women with a life-long history of morbid obesity.
She was operated on in January 2000 with a laparoscopic BPD/DS with 100 ml gastric pouch, 150 cm of alimentary limb and 100
cm of common channel. Before this operation, her weight was 170 kg, with BMI 64 kg/m2. She lost most of her excess weight within 17 months after surgery and was regaining weight at 77 kg and BMI 29 kg/m2. Upper GI series showed a markedly dilated gastric pouch. Her second surgery consisted of a laparoscopic sleeve partial gastrectomy
along the greater curvature using endo GIA staplers with bovine pericardium for reinforcement of the stapler line. Results:
No postoperative complications occurred. The patient was discharged on the first postoperative day. Significant further weight
reduction was noted, and at 10 months after surgery, her weight is 61 kg with BMI 22. Conclusion: A repeat laparoscopic gastric
sleeve resection was performed for inadequate weight loss after BPD/DS, and resulted in further weight reduction. 相似文献
12.
Duodenal Switch Without Gastric Resection after Failed Gastric Restrictive Surgery for Morbid Obesity 总被引:1,自引:1,他引:0
Di Betta E Mittempergher F Di Fabio F Casella C Terraroli C Salerni B 《Obesity surgery》2006,16(3):258-261
Background: Several surgical treatments have been proposed for patients in whom gastric restrictive operations have failed.
The aim of this study was to analyze the effectiveness and safety of duodenal switch (DS) with restoration of normal gastric
capacity in such patients. Methods: Between May 2001 and May 2003, 11 DS with restoration of normal gastric capacity were
performed without other gastric procedures in patients who had had previous gastric restrictive operations which had failed
because of inadequate weight loss or weight regain. Data were collected and follow-up was 2 years for all patients. Results:
At the original operation, mean BMI was 47.3 (range 38-53) kg/m2, and mean age was 42 years. 7 of the 11 patients (63.6%) had previous vertical banded gastroplasty, and 4 of the 11 (36.4%)
had previous laparoscopic adjustable gastric banding. Mean percentage weight regain and mean BMI at the time of DS were 92.1%
and 44.6 (range 35-53) kg/m2 respectively. After the second operation, mean BMI at 6 months was 35.4 kg/m2, at 12 months 31.7 kg/m2 and at 24 months 28.6 kg/m2. The % excess weight loss was 41.1 after 6 months, 56.6 after 12 months and 69.6 after 2 years. There was minor morbidity
and no mortality. Conclusion: After this experience, we suggest that patients with failed gastric restrictive operations (weight
regain or inadequate weight loss) may undergo DS with restoration of normal gastric capacity. This second operation proved
to be safe and effective. 相似文献
13.
BackgroundWeight loss failure after laparoscopic gastric banding (LAGB) can occur in ≤25% of patients. Conversion to a malabsorptive procedure might provide more durable weight loss. The present study evaluated biliopancreatic diversion with duodenal switch (BPD/DS) after LAGB failure with a 3-year follow-up period.MethodsA total of 35 patients underwent BPD/DS after LAGB failure and were prospectively analyzed using a multidisciplinary approach. Weight indexes, co-morbidities, complications, morbidity/mortality, and nutritional status were analyzed.ResultsExcess weight decreased from 91% (134 kg, body mass index 48 kg/m2) to 75% (124 kg, body mass index 44 kg/m2) after LAGB failure and decreased further to 40% (100 kg, body mass index 35 kg/m2) after BPD/DS. The mean percentage of excess weight loss was 55% after LAGB and BPD/DS together and 48% after BPD/DS alone. The incidence of co-morbidities, such as diabetes, sleep apnea, hypertension, hyperlipidemia, joint problems, and chronic obstructive pulmonary disease was reduced after BPD/DS. Nutritional deficiencies were already present after LAGB failure (e.g., iron, ferritin, vitamins B12, B6, A, D, and E, albumin, and calcium) and either increased (folic acid, potassium, and vitamin B12), remained stable (iron, ferritin, vitamin A), or decreased after BPD/DS (albumin and vitamins B6 and E).ConclusionBPD/DS provided substantial weight loss after LAGB failure and reduced the incidence of obesity-related co-morbidities during a 3-year period. Long-term nutritional follow-up is advocated for all patients after malabsorptive BPD/DS. 相似文献
14.
Diker D Vishne T Maayan R Weizman A Vardi P Dreznik Z Seror D Ram E 《Obesity surgery》2006,16(8):1057-1061
Background: Several endocrine abnormalities are reported in obesity. In an earlier study, we found that the changes in BMI following
laparoscopic adjustable gastric banding (LAGB) were associated with changes in hormone profiles such as insulin and proinsulin.
In the current study, we explored the changes in plasma adiponectin levels in morbidly obese subjects who lost abundant weight
following LAGB. Methods: 23 adult morbidly obese patients (15 females), aged 21-56 years, were studied. Blood samples were collected before, and 6
and 14 months after LAGB. The plasma adiponectin levels were determined by commercial kit (B-Bridge International, Inc). Statistical
analysis was based on one-way repeated measures ANOVA, followed by Student-NewmanKeuls post-hoc test. Regression model was
used to look for predictors of adiponectin change after LAGB. Results: Mean BMI before surgery was 46.04±4.44 kg/m2, and decreased significantly by 18% 6 months after surgery to 37.67±4.47 kg/m2. BMI further decreased by 32% 14 months after surgery to a mean of 31.30±4.65 kg/m2 (P =.000). The mean adiponectin level before surgery was 3997±1766 μg/ml, and increased significantly by 16% to 4763±1776 μg/ml
6 months after surgery, and to 6336±3292 μg/ml (37%) 14 months after surgery. Although BMI persistently decreased, while adiponectin
persistently increased, BMI did not correlate with adiponectin. Conclusion: In morbidly obese patients who underwent LAGB, adiponectin levels persistently increased, probably due to the reduction of
visceral fat mass. Adiponectin plasma increase was correlated with proinsulin levels prior to the surgery. The interaction
between adiponectin, proinsulin and BMI change in morbid obesity merits further investigation. 相似文献
15.
Comparison of rates of resolution of diabetes mellitus after gastric banding, gastric bypass, and biliopancreatic diversion 总被引:1,自引:0,他引:1
Parikh M Ayoung-Chee P Romanos E Lewis N Pachter HL Fielding G Ren C 《Journal of the American College of Surgeons》2007,205(5):631-635
BACKGROUND: Bariatric operation is the most effective treatment for diabetes mellitus in the morbidly obese. The purpose of this study is to compare the rate of resolution of diabetes mellitus after three common laparoscopic bariatric procedures: laparoscopic adjustable gastric banding (LAGB), Roux-en-Y gastric bypass (RYGB), and biliopancreatic diversion with or without duodenal switch (BPD/DS). STUDY DESIGN: All data were prospectively collected and entered into an electronic registry. Characteristics evaluated for this study included preoperative age, body mass index, duration of diabetes, race, gender, operative time, length of stay, percent excess weight loss, oral hypoglycemic requirements, and insulin requirements. RESULTS: A total of 282 bariatric patients with diabetes mellitus were analyzed (218 LAGB, 53 RYGB, and 11 BPD/DS). Preoperative age (46 to 50 years), body mass index (46 to 50; calculated as kg/m(2)), race and gender breakdown, and baseline oral hypoglycemic (82% to 87%) and insulin requirements (18% to 28%) were comparable among the three groups (p = NS). Percent excess weight loss at 1, 2, and 3 years was: 43%, 50%, and 45% for LAGB; 66%, 68%, and 66% for RYGB; and 68%, 77%, and 82% for BPD/DS (p < 0.01 LAGB versus RYGB and LAGB versus BPD/DS at all time intervals). At 1 and 2 years, the proportion of patients requiring oral hypoglycemics postoperatively was 39% and 34% for LAGB; 22% and 13% for RYGB; and 11% and 13% for BPD/DS (p = NS). At 1 and 2 years, the proportion of patients requiring insulin postoperatively was 14% and 18% for LAGB; 7% and 13% for RYGB; and 11% and 13% for BPD/DS (p = NS). CONCLUSIONS: Despite the disparity in percent excess weight loss between LAGB, RYGB, and BPD/DS, the rate of resolution of diabetes mellitus is equivalent. 相似文献
16.
Preparation of Extremely Obese Patients for Laparoscopic Gastric Banding by Gastric Balloon Therapy 总被引:5,自引:3,他引:2
Background: In super, super obese patients (body mass index [BMI] >60), especially those with extreme intra-abdominal fat
deposition, the technical difficulties in laparoscopic procedures increase. The purpose of this study was to evaluate whether
gastric balloon therapy (GBT) can improve the operative conditions for laparoscopic adjustable gastric banding (LAGB) in extremely
obese patients. Materials and Methods: From April 1995 to August 1998, 196 LAGBs were performed. In 15 patients (7 female
and 8 male), median age 38.8 years (range 17-54), who had been selected as suitable candidates for bariatric surgery, preoperative
GBT was studied. Fourteen patients were extremely obese (BMI 60.2 kg/m2 [range 58-72]). One 17-year-old boy with BMI 46.6 kg/m2 was also treated. The Bioenterics Intragastric Balloon (BIB) was used. The placement, the volume modification, and the removal
of the BIB were performed endoscopically. Close follow-up was possible in 14 patients. After balloon removal, 13 patients
underwent LAGB. Results: In 14 of 15 cases, GBT was successful. There was only one ballon dysfunction. The mean weight loss
was 18.1 kg, and the median duration of balloon therapy was 16.8 weeks. After balloon removal, body weight started to increase.
Conclusions: In our experience, the gastric balloon can improve the conditions for laparoscopic surgery in super and in super,
super obese patients. There was no conversion to open surgery. The effect of weight loss is much less than immediately after
LAGB. However, after failure of all conservative treatments to reduce the preoperative body weight, the GBT seems to be the
last possibility. 相似文献
17.
Gastrointestinal Quality of Life Following Laparoscopic Adjustable Gastric Banding in Asia 总被引:5,自引:5,他引:0
Background: Laparoscopic adjustable gastric banding (LAGB) is a safe and effective treatment for morbid obesity. Previous
studies in Western countries disclosed a significant improvement in co-morbidities and health-related quality of life. Data
from Asia and regarding the specific GI quality of life following LAGB are lacking. Methods: From May 2002 to May 2005, 107
consecutive patients – 48 men and 59 women, with mean age 31.4 years (range 17-57 years) with morbid obesity (mean weight
115.8 kg, range 81-174 kg; mean BMI 41.3 kg/m2, range 32.0-59.8 kg/m2) underwent LAGB in a prospective trial. All bands were placed via the pars flaccida technique. Quality of life was measured
by the Gastrointestinal Quality of Life Index (GIQLI), a 36item questionnaire before LAGB, and at 3, 6, 12 and 24 months after
surgery. Results: All procedures were performed laparoscopically with no conversions. There was neither intra-operative complications
nor major postoperative complications. Minor complications occurred in 3 patients (2.8%); all were transient stoma obstruction.
At follow-up, only one band (0.94%) was removed at 3 months postoperatively because of the patient's intolerance. No gastric
slippage occurred. 4 patients (3.7%) had tubing problems and required revision surgery for port adjustment. Mean BMI decreased
from 41.3 to 33.1 after 2 years. Percent excess BMI loss averaged 48.1% at 2 years (range 6.7-139.2). All co-morbidities were
eliminated significantly. 80% of patients were satisfied with the results at 2 years. However, the GIQLI score remained similar
before and after surgery. Preoperative score was 110.8+15 points. The score became 116.2+13, 114.7+13, 108.5+14 and 107.2+17
at 3, 6, 12 and 24 months. The patients had improvement in 3 domains of general health (social, physical and emotional functions),
but decrease in the domain of symptoms. Conclusion: Although LAGB was successful in weight loss and resolution of co-morbidities
in morbidly obese patients, the GIQLI did not improve. This feature will be the major disadvantage of LAGB. 相似文献
18.
Laparoscopic Reoperative Bariatric Surgery: Experience from 27 Consecutive Patients 总被引:12,自引:6,他引:6
Gagner M Gentileschi P de Csepel J Kini S Patterson E Inabnet WB Herron D Pomp A 《Obesity surgery》2002,12(2):254-260
Background: 10 to 25% of patients undergoing bariatric surgery will require a revision, either for unsatisfactory weight loss
or for complications. Reoperation is associated with a higher morbidity and has traditionally been done in open fashion.The
purpose of this study was to determine the safety and efficacy of reoperative surgery using a laparoscopic approach. Methods:
A retrospective review of medical records over a 22-month period was conducted. 27 consecutive obesity surgery patients, who
had undergone a laparoscopic revision, were identified. 26 of the 27 patients were women. The average age was 40.3 years (range
20 to 58 years) and average original preoperative body mass index (BMI) was 51.6 kg/m2 (range 42 to 66.5).The 27 primary bariatric
operations consisted of vertical banded gastroplasty (12), gastric band placement (9) and gastric bypass (6). 17 of them were
open procedures. After the primary surgery, the lowest average BMI was 37.6 kg/m2 (range 21 to 52), which increased to 42.7 kg/m2 (range 29 to 56) before reoperation. 24 of the 27 reoperations were indicated for insufficient weight loss. On average, revision
was undertaken 52 months after the primary procedure (range 12 to 240 months). Results: 24 of the 27 laparoscopic reoperations
were conversions to a gastric bypass. A second reoperation was indicated for insufficient weight loss on four occasions. In
one case, conversion to open surgery was required. The average operative time was 232 ± 18.5 minutes (range 120 to 480) and
length of hospital stay was 3.7 days (range 1 to 9). 22% percent of patients (6) experienced complications, including pneumothorax,
gastric remnant dilation, gastrojejunostomy stenosis, port-site hernia and protein malnutrition. There was no mortality in
the study.The average BMI was 35.9 kg/m2 (range 27 to 45.5) 8 months after surgery (range 1 to 22 months). Compared with a preoperative BMI of 42.7 kg/m2, the weight loss was statistically significant (p<0.001). Conclusion: Our results compare favorably with those reported
for open reoperative bariatric surgery. A laparoscopic approach may be considered a feasible and safe alternative to an open
operation. 相似文献
19.
Does Gastric Dilatation Limit the Success of Sleeve Gastrectomy as a Sole Operation for Morbid Obesity? 总被引:6,自引:10,他引:6
Langer FB Bohdjalian A Felberbauer FX Fleischmann E Reza Hoda MA Ludvik B Zacherl J Jakesz R Prager G 《Obesity surgery》2006,16(2):166-171
Background: Sleeve gastrectomy as the sole bariatric operation has been reported for high-risk super-obese patients or as
first-step followed by Roux-en-Y gastric bypass (RYGBP) or duodenal switch (DS) in super-super obese patients. The efficacy
of laparoscopic sleeve gastrectomy (LSG) for morbidly obese patients with a BMI of <50 kg/m2 and the incidence of gastric dilatation following LSG have not yet been investigated. Methods: 23 patients (15 morbidly obese,
8 super-obese) were studied prospectively for weight loss following LSG. The incidence of sleeve dilatation was assessed by
upper GI contrast studies in patients with a follow-up of >12 months. Results: Patients who underwent LSG achieved a mean
excess weight loss (EWL) at 6 and 12 months postoperatively of 46% and 56%, respectively. No significant differences were
observed in %EWL comparing obese and super-obese patients. At a mean follow-up of 20 months, dilatation of the gastric sleeve
was found in 1 patient and weight regain after initial successful weight loss in 3 of the 23 patients. Conclusion: LSG has
been highly effective for weight reduction for morbid obesity even as the sole bariatric operation. Gastric dilatation was
found in only 1 patient in this short-term follow-up. Weight regain following LSG may require conversion to RYGBP or DS. Follow-up
will be necessary to evaluate long-term results. 相似文献
20.
Parikh MS Laker S Weiner M Hajiseyedjavadi O Ren CJ 《Journal of the American College of Surgeons》2006,202(2):252-261
BACKGROUND: Several surgical treatment options for morbid obesity exist. Currently, there are no studies that objectively compare complication rates after laparoscopic bariatric operations performed at a single institution. We objectively classify and compare complications resulting from laparoscopic adjustable gastric banding (LABG), Roux-en-Y gastric bypass (RYGB), and biliopancreatic diversion (BPD) with duodenal switch (DS). STUDY DESIGN: A retrospective review of a prospective database of all patients undergoing laparoscopic bariatric operation was performed. Complications were categorized according to severity score using a well-described classification system and compared between procedures. RESULTS: From September 2000 to July 2003, 780 laparoscopic bariatric operations were performed: 480 LAGB, 235 RYGB, and 65 BPD+/-DS. There was one late death. Total complication rates were: 9% for LAGB, 23% for RYGB, and 25% for BPD+/-DS. Complications resulting in organ resection, irreversible deficits, and death (grades III and IV) occurred at rates of 0.2% for LAGB, 2% for RYGB, and 5% for BPD+/-DS. LAGB group had a statistically significant lower overall complication rate, both by incidence and severity, as compared with other groups (p < 0.001). After controlling for differences of admission body mass index, gender, and race, the LAGB group had an almost three and a half times lower likelihood of a complication compared with the RYGB group (odds ratio, 3.4; 95% CI, 2.2-5.3, p < 0.001) and had an over three and a half times lower likelihood of a complication compared with the BPD with DS group (odds ratio, 3.6; 95% CI, 1.8-7.1, p < 0.001). There was no statistically significant difference between complication rates of RYGB and BPD+/-DS. CONCLUSIONS: Bariatric operation complication rates range from 9% to 25%; very few complications are serious. Laparoscopic adjustable gastric banding is the safest operation in terms of complication rate and severity when compared with laparoscopic Roux-en-Y gastric bypass or laparoscopic malabsorptive operations. 相似文献