鼻内镜下鼻腔多形性腺瘤切除一例

患者女,26岁.以"发现右侧鼻腔肿块4年、鼻塞4周"为主诉就诊.4年前挖鼻时感觉右侧鼻腔有肿块,无任何不适,未予诊治.4周前感冒后出现右侧鼻塞,在当地医院检查发现右侧鼻腔新牛物,即来我院,门诊以"右侧鼻腔新生物"收住院.体检:外鼻无畸形,右侧鼻腔可见一暗红色新生物,表面光滑,质中,基底较广,位于鼻中隔右侧面中后部,与周边黏膜边界清楚,堵塞右侧鼻腔.左侧鼻腔无异常.鼻窦CT显示右侧鼻腔新生物,各鼻窦结构正常.病检检查结果:右侧鼻腔多形性腺瘤.     

鼻-鼻窦多形性腺瘤

多形性腺瘤发生于鼻-鼻窦的很少见,主要表现为单侧鼻塞进行性加重,或无痛性鼻-鼻窦肿块,可伴有涕中带血。局部检查可见肿瘤呈圆形或椭圆形,表面光滑或不平,中等硬度,有完整的包膜。瘤体切面呈灰白色或红色,由于结构成分复杂,较易误诊,而免疫组化有助于诊断。多形性腺瘤治疗方式以手术为主,对X线不敏感,故不主张放射治疗或化学治疗,完整切除是降低复发率的主要措施。术后复发的病例可以再次手术。多形性腺瘤的另一特征是具有恶变倾向。     

耳廓多形性腺瘤一例

耳廓多形性腺瘤一例胡晓川，何广文患者，男，３８岁。自述左外耳肿物４月余，时有隐痛。体检：一般状态尚好，左耳对耳轮见有一０．８ｃｍ×０．６ｃｍ大小肿物，质偏硬，活动度较差。局麻下将肿物切除，术中见肿物与周围组织界线较清楚，但无明显包膜。病检：肿物近似扁...     

会厌多形性腺瘤一例

多形性腺瘤，又称混合瘤，主要发生在腮腺等大涎腺以及口腔、上呼吸道等处的小涎腺，也可见于皮肤。但发生于会厌喉面的较少见，现报道一例。[第一段]     

鼻背部脊索瘤一例

患者女 ,30岁 ,于 1998年 7月住院。于 1997年 6月发现鼻背部右侧一渐隆起包块 ,无特殊不适 ,半年后包块渐增至 2 .0ｃｍ× 1.0ｃｍ大小 ,于我院门诊取活体组织检查 ,报告为脊索瘤 ,他院行手术切除。术后半年因局部包块复发 ,渐增大 ,并局部疼痛入我院。入院查体见右侧鼻背部约 3.0ｃｍ× 2 .0ｃｍ×0 .4ｃｍ表面不平、被覆完整皮肤的包块 ,质稍硬 ,不活动 ,稍有压痛。右侧鼻腔内可见包块位于中鼻道前部 ,表面粘膜光滑。全身检查正常 ,其他部位未见有肿物。ＣＴ检查 :右侧鼻背及鼻腔软组织肿块 ,右侧鼻骨有虫蚀样破坏。颅底及脊椎Ｘ线摄片未…     

鼻及鼻窦多形性腺瘤15例报告

目的：探讨鼻及鼻窦多形性腺瘤的临床特点和治疗方法。方法：15例鼻及鼻窦多形性腺瘤患者，行上颌窦根治术2例，用圈套器作鼻息肉切除术2例，鼻侧切开术10例，上颌骨切除术1例。结果：首次术后无复发7例，复发6例，种植性复发1例，恶变(癌肉瘤)1例。6例复发者再次手术后无复发2例，复发2例，恶变2例；1例种植性复发者行放疗60Gy无效死亡。结论：鼻及鼻窦多形性腺瘤误诊率高，复发率高，多次手术易恶变；治疗的关键在于首次手术采用大术野彻底清除病灶，如怀疑是该肿瘤则术中应作快速切片，术前尽量不做活检以防瘤体破裂；预后与肿瘤复发和恶变有关。     

鼻腔多形性腺瘤恶性变一例

患者男，69岁。以右侧鼻塞5年，鼻旁隆起及鼻外肿块7个月于2006年2月23日入院。患者5年前因右侧鼻塞就诊于当地医院，表面麻醉下经前鼻孔行鼻腔肿物摘除，病理报告为鼻腔混合瘤。术后鼻腔通气较好，未曾复诊。半年前开始出现渐进性鼻塞及少量涕中带血，右侧鼻前孔有肿物突出伴右侧鼻背隆起畸形。4个月前在当地医院CT检查示右鼻腔前部有光滑肿物，骨质完整，未行治疗。近1个月来，     

鼻咽部多形性腺瘤一例报告

多型性腺瘤属交界性肿瘤。唾液腺以外的多形性腺癌很少见,位于鼻咽部者更属罕见。我科曾遇1例,报告如下。 女,64岁,农民。患者自两月前开始出现右鼻腔有血凝块,以后反复出现右鼻腔少量出血,有时血液从后鼻孔流出,伴轻度鼻塞。于1986年5月22     

会厌多形性腺瘤1例

患者,男,43岁,因声嘶伴咽部梗阻感1年于2013年1月28日入院。患者无吞咽及呼吸困难。电子喉镜检查提示：会厌喉面左侧游离缘处可见巨大白色球形新生物。表面光滑,界清（图1）。于1月31日在全身麻醉下行支撑喉镜下会厌新生物切除术,术中见会厌喉面左侧游离缘处直径约1．5cm黄白色球形新生物,表面光滑,界清,质中偏韧。     

A case of pleomorphic adenoma of the nasal septum

We report a rare case of pleomorphic adenoma arising from the nasal septum. A 32-year-old woman presented with a 3-week-history of left-sided nasal obstruction. Computed tomographic scans revealed an oval mass, measuring about 30 mm in its greatest dimension, in the left anterior nasal cavity. The tumor arose from the anterior part of the nasal septum, and was removed endoscopically with endonasal approach. The microscopic finding showed a lobular and duct-like structures consisting of a loose chondromyxoid stroma. This lesion had histological characteristics of a pleomorphic adenoma, and this was confirmed by immunohistochemical expression of cytokeratin and S-100 protein. Her post-operative course was uneventful, and she is currently free from the disease 8 months after surgery. Diagnosis, clinical behavior and treatment of pleomorphic adenoma of the nasal septum are reviewed from perusal of the literature.     

Metastasizing pleomorphic adenoma of the nasal septum

Pleomorphic adenoma is the most common benign tumor of glandular tissue occurring in the head and neck region. There have been several reports of metastasis of this benign-appearing tumor from the salivary glands to distant sites, suggesting hematogenous spread and implantation. Although occurrence of pleomorphic adenoma on the nasal septum has been described, to our knowledge this is the first reported case of recurrent septal pleomorphic adenoma with histologically benign tissue in an enlarged metastatic ipsilateral submandibular lymph node, suggesting lymphatic spread. The literature concerning the subject is reviewed. Wide septal excision and modified neck dissection is the recommended treatment.     

Huge pleomorphic adenoma of nasal cavity

Pleomorphic adenoma is a common benign tumour of the salivary gland that has elements of both epithelial and mesenchymal tissue. It is commonly seen in major salivary glands, parotid being the most common site followed by submandibular gland. However it can sometimes arise from minor salivary glands that are distributed throughout the upper aerodigestive tract and paranasal sinuses. We report a case of a 45 yrs. Old male patient, who presented with progressive nasal blockage and intermittent minor episodes of epistaxis from left nostril for 1 ? years. Lateral Rhinotomy revealed a well encapsulated lesion attached to the nasal septum, which was excised completely. Histopathology revealed it to be Pleomorphic Adenoma without any features of malignancy. Lesion is a rare one hence reported.     

A rare case of pleomorphic adenoma of lateral wall of nasal cavity--with special reference of statistical observation of pleomorphic adenoma of nasal cavity in Japan

Pleomorphic adenoma, which is also called mixed tumor is considered to occur favorably in major salivary glands such as parotid and submandibular glands, and rarely in the nasal cavity, pharynx, larynx, trachea, and lacrimal gland. We reported here a rare case of pleomorphic adenoma (2.9 X 2.2 X 1.7 cm3) developed from the lateral wall of right nasal cavity in a 43-year-old woman. Statistical observation of pleomorphic adenoma of the nasal cavity in Japan was made and comparative study was also made between such adenoma and that in the parotid gland. In Japan, 41 cases of pleomorphic adenoma originated in the nasal cavity have been reported so far including ours. These cases had age of onset of 16-74 years, averaging 44.6 years. Sex ratio showed female predominance. No significant difference was noted in affected sides sites. Chief complaints were represented mostly by nasal obstruction (29 cases; 71%) and nasal bleeding (23 cases; 56%). Tumors were surgically extirpated in all cases. One recurrent case (2.4%) was reported and another malignant case (2.4%) was also reported. 4 cases (9.8%) were originated in the lateral wall of nasal cavity and all of the other cases were in the nasal septum. In comparison with pleomorphic adenoma developed in parotid gland in Japan, sex ratio was 1:1.8 compared with 1:2.1 for parotid gland with almost similar tendency. Age of onset averaged 44.6 compare with 32.8 years for parotid gland, with a little advance in age.(ABSTRACT TRUNCATED AT 250 WORDS)     

鼻腔混合瘤的临床分析

目的探讨鼻腔混合瘤的临床表现、病理特点及治疗方法,以提高对此病的诊疗水平。方法回顾性分析6例鼻腔混合瘤患者的临床资料,根据术前鼻内镜和鼻窦CT等术前评估选择手术径路;其中2例行鼻侧切开术,4例行鼻内镜下肿瘤切除术。结果鼻腔混合瘤原发于鼻中隔者5例、鼻咽顶后壁1例;术后随访3年,5例痊愈,1例复发。结论鼻腔混合瘤虽属良性肿瘤,但术后易复发,首次彻底切除是预防复发的关键,术后需定期随访。     

Immunohistochemical study of pleomorphic adenoma of the nasal septum.

A rare case of pleomorphic adenoma of the nasal septum is reported. A 48-year-old man complaining of nasal obstruction and nasal bleeding was referred to our hospital for treatment of a left nasal tumor. The tumor, including the nasal septum, was resected by the modified Denker operation and lateral rhinotomy. The tumor was firm, parenchymatous, pedunculated, and 24 x 22 x 14 mm in size. Pathological examination revealed pleomorphic adenoma with slight cellular atypism. Immunohistochemical observations suggested that characterization of this tumor might be similar to pleomorphic adenoma of the parotid gland.