Precisa活检针在螺旋CT引导下经皮肺穿刺活检诊断肺部病变准确性的分析

目的 分析影响螺旋CT引导下应用Precisa活检针经皮肺穿刺活检诊断肺部病变准确率的因素.方法 回顾性分析87例螺旋CT定位引导下应用Precisa活检针经皮肺穿刺活检资料,对切取病变组织肉眼观与手术病理结果的关系,穿刺的成功率以及并发症进行分析.结果 病灶穿刺成功率100%.确定病理诊断78例(89.65%),未明确诊断9例;术后并发症发生率19.5%,其中气胸8例,局部出血5例,咯血2例,经相应处理后缓解.结论 螺旋CT引导下用Precisa活检针经皮肺穿刺活检成功率与病理诊断率高,可为临床治疗方法的选择提供可靠依据.     

弹簧芯状活检针在CT引导经皮肺穿刺活检中的应用

目的：探讨CT引导下使用弹簧芯状活检针行比皮肺穿刺活检的诊断准确性和并发症发生率。方法：38例使用弹簧芯状活检针的经皮肺穿刺活检。CT扫描确定并引导穿刺途径,达预定位置取材。结果：35例有明显的病理诊断,诊断准确性92％,恶性肿瘤和良性病变的诊断准确性分别为97％和100％。活后并发气胸4例,咯血1例,结论：CT引导下使用弹簧芯状活检针行经皮肺穿刺活检的气胸发生率与细针抽吸相近,使弹簧芯状活检针行CT引导下肺穿刺活检可以提高诊断的准确性。     

经皮肺穿刺活检的临床应用

目的：对肺内肿物行穿刺活检病理学确诊。方法：20例肺内肿物患者在X线或CT定位监视下经皮肺穿刺细针吸活检，组织细胞学病理检查。结果：一次穿刺活检病理确诊率达95％，并发症少。结论：是一种微创、快速的诊断技术，对肺内肿物可提供准确的病理学诊断。     

两种活检针在经皮胸肺穿刺活检中的应用

目的：观察两种不同活检针在CT导向下经皮胸肺穿刺活检的准确率和并发症的发生率。方法：对17例肺内直径≤2cm的病灶用22G抽吸活检针行经皮胸肺穿刺活检；对22例直径〉2cm的病灶用18Gmedi—tech同轴切割针行经皮胸肺穿刺活检。结果：22G抽吸活检针活检确诊率为76．5％，并发症发生率为11．7％；18G同轴切割针活检确诊率为91%，并发症发生率为13．6%。结论：1、根据病灶的大小、位置，选择不同的穿刺针获取不同大小的组织．提高了穿刺活检确诊率和减少了并发症的发生率；2、除不能合作者外，CT导向经皮胸肺穿刺技术可用于几乎所有胸部病灶的活检。     

肺隐球菌病CT导向下经皮穿刺活检的诊断价值

目的：探讨CT导向下经皮穿刺肺活检对肺隐球菌的诊断价值。方法：回顾性分析11例经皮肺穿刺活检病理证实的肺隐球菌病的病例资料,所有病例均行CT检查,其中9例平扫,2例直接增强,11例行细针抽吸及切割活检送病理组织学检查。结果：CT显示单发肺结节4例,多发肺结节5例,2例呈实变样表现,11例经细针抽吸活检2例可疑隐球菌病,切割活检11例均确诊为隐球菌病,发生少量气胸1例。结论：对于肺部难以确诊的肺隐球菌病例,CT导向下经皮穿刺切割活检是一种安全有效的方法。     

改良的CT引导下同轴法经皮肺穿刺活检术应用

目的：探讨CT引导下同轴法经皮肺穿刺活检术的临床应用价值。方法：选择因肺内病变需活检的116例患者,所有患者均采用CT引导下自动活检枪同轴法经皮肺穿刺活检术。结果：116例患者均成功获取病理标本,穿刺成功率100％,病变阳性率94．8％,并发症6例（5．2％）,经对症处理后2～7天后患者身体逐渐恢复。结论：改良CT引导下经皮肺穿刺活检术器材简单易得,费用低廉操作简便,穿刺成功率高、并发症发生率低。     

CT导向经皮肺部病变穿刺活检的临床效果

目的探讨CT导向经皮肺穿刺活检的临床应用和体会。方法 66例经CT导向做肺穿刺活检的患者,肺内肿块为62例,胸膜病变2例,肋骨及胸腺病变各1例,采用切割针和抽吸针。结果经一次穿刺成功诊断59例。穿刺后病理怀疑肺鳞状细胞癌,结果为肺脓肿1例;第一次穿刺假阴性6例,其中有2例再次穿刺成功诊断为肺腺癌和鳞状细胞癌。本组穿刺活检总的成功率为92.4%。结论 CT导向经皮肺穿刺活检是一项安全有效的诊断方法,CT的准确定位和良好的穿刺技术及病理科的配合和熟练的技术操作是提高活检成功率的重要因素。     

CT引导下经皮穿刺活检在骨骼病变中的应用价值

目的：评价CT引导下经皮穿刺活检在骨骼病变中的诊断价值。方法：对108例骨骼病变行CT引导下活检,每例常规取材2～3次,其中62例病灶区域灶周硬化明显者采用Ackermann骨钻针,35例破坏灶或有明显骨皮质薄弱区者采用切割式活检针,11例有明显灶区液化者采用抽吸式活橙针。结果：108例中102例获得病理诊断,穿刺活检取材阳性率为94．3％,其中97例穿刺结果与手术病理结果相符、5例不相符,其组织学定性诊断符合率为95．0％。6例假阴性者包括4例增生硬化性病灶、2例为液化灶。结论：CT引导下经皮穿刺活检在骨骼病变中的应用安全可靠,并发症少,可得到准确的病理诊断。     

孤立性肺结节的CT引导下经皮肺穿刺活检

目的　探讨CT引导下经皮肺穿刺活检术对孤立性肺结节的诊断价值。方法　回顾性分析于 1993 -0 3～ 2 0 0 1-0 3期间行CT引导下经皮肺穿刺活检并经手术病理、临床治疗或随访观察证实的资料完整的 61例孤立性肺结节病灶。采用美国Cook公司的抽吸式活检针和套管式自动活检枪 ,选择最佳穿刺层面及穿刺点获取标本。结果　 61例孤立性肺结节病灶中经手术病理、临床治疗或随访观察证实为恶性肿瘤者 47例 (原发性支气管肺癌 43例 ,转移癌 4例 ) ,良性病变者 14例。而CT引导下经皮肺穿刺活检诊断为恶性肿瘤者 43例 ,良性病变者 9例。并发症 :气胸 12例 (19.8% ) ,出血 5例 (8.2 % ) ,咯血 4例 (6.6% )。结论　孤立性肺结节的CT引导下经皮肺穿刺活检是一种创伤小而实用的定性诊断方法 ,具有较高的临床应用价值     

CT引导下肺穿刺活检的临床应用

目的评价CT引导下肺穿刺活检的临床应用价值。方法回顾性分析经手术或病理证实的CT引导下肺穿刺活检30例。活检的穿刺针为Ch i ba 18G抽吸针及切割针，要点包括选择最佳层面、精确定位选择穿刺点及多方位不同针道快速抽吸和切割。结果30例中明确诊断26例，其中腺癌7例，鳞癌6例，小细胞癌1例，转移瘤1例。低分化腺癌1例，胸膜间皮瘤1例，肺泡细胞癌1例，肺结核5例，炎性假瘤3例。未明确诊断4例，发生气胸2例，少量咯血2例，皮下气肿1例。穿刺活检确诊率86．7％。结论CT引导下肺穿刺活检对肺部病变确诊率高、并发症少，是一种安全有效、简便实用的检查方法，应广泛推广使用。     

Hilar masses: evaluation with CT-guided biopsy after negative bronchoscopic examination

Computed tomography (CT)-guided biopsies of 20 patients with hilar masses were performed after non-diagnostic bronchoscopic examination. Bronchoscopy included washings, brushings, routine biopsy, and, in many cases, transbronchial biopsy. In all but one case (95%), biopsy with a 22-gauge needle permitted a cytologic diagnosis of malignancy. In 14 of the 19 cases (74%), a diagnosis of primary lung carcinoma involving the hili was made, and in the remaining five of the 19 (26%), metastatic hilar adenopathy from an extrathoracic primary tumor was identified. A pneumothorax rate consistent with our average rate for CT-guided biopsies (25%) was obtained, and only one patient required chest tube placement. In this series, CT-guided biopsies of hilar masses were more consistently successful in obtaining tissue for diagnosis than were bronchoscopic biopsies. Transthoracic needle aspiration biopsy may be the preferred initial diagnostic procedure in many patients with hilar masses.     

Necrotizing granuloma of the lung: imaging characteristics and imaging-guided diagnosis

OBJECTIVE: The purpose of this study was to assess CT findings and the sensitivities of imaging-guided fine-needle aspiration (FNA) biopsy and core needle biopsy in the diagnosis of necrotizing granuloma of the lung. CONCLUSIONS: The CT characteristics of necrotizing granuloma are indistinguishable from those of malignant tumors; tissue diagnosis therefore is necessary. Core needle biopsy is a sensitive method for diagnosing necrotizing granuloma of the lung, but FNA biopsy is insufficient for diagnosis.     

CT-guided percutaneous lung biopsy using a cutting needle and an automated biopsy gun. Comparison with lung biopsy using a manual aspiration needle]

Twenty-five percutaneous lung biopsies using a 20-gauge cutting needle and automated biopsy gun (ABG) were performed under CT guidance in 25 patients with thoracic lesions. This procedure was compared with that using a 21-gauge manual aspiration needle in 36 patients (40 examinations, 37 lesions) in terms of success rate, rate of correct diagnosis, mean examination time and rate of complications. Specimens obtained from lung biopsy were graded by a histopathologist according to quality and quantity from 0 to 4 (pathological score). There were no statistically significant differences between the two procedures in terms of success rate, rate of correct diagnosis and rate of complications; only the time required was significantly different. However, sufficient biopsy material and a mean pathological score of G-II 2.8 (that of G-I was 1.9, p less than 0.05) could be obtained by the biopsy procedure using the cutting needle. The above results indicated that aspiration needle biopsy was adequate for lung biopsy, but that a cutting needle and ABG should be used when a good biopsy specimen is needed for tissue diagnosis.     

CT导向经皮肺穿刺活检(附42例报道)

目的：作就４２例ＣＴ导向经皮肺穿刺活检,对体表标记定位方法,穿刺过程,并发症,准确率,以及穿刺抽吸关键性手法进行探讨,提出ＣＴ导向经皮肺穿刺活检是对肺部疑难疾病诊断的一种有效方法。穿刺总准确率９５．２％,恶性病变阳性率８５．７％;没有假阳性。除１例气胸外,余６例轻微并发症不需要特殊处理。     

应用生理盐水预防经皮肺穿刺活检中气胸发生的初探

目的：探讨在经皮肺穿刺活检术中应用生理盐水预防气胸发生的效果。方法：经皮肺穿刺活检病例136例,其中年龄〈55岁36例,年龄〉55岁100例（随机分成A、B两组,各50例）,其中B组在经皮肺穿刺活检术中经穿刺针注射生理盐水。结果：136例均穿刺成功,并发气胸的情况：年龄〈55岁组发生气胸2例,气胸量〈10%。年龄大于55岁的气胸发生率较高,A组发生气胸14例,其中12例气胸量〈10%、2例〉30%,有皮下气肿1例;B组发生气胸4例,气胸量均〈10%。B组的气胸发生率明显低于A组,B组无1例因注射生理盐水而出现咳嗽、咳痰等不适。结论：经皮肺穿刺活检术中注射生理盐水可在一定程度上堵塞穿刺针穿刺肺胸膜的针孔道,减少气胸的发生率。     

Combining fine-needle aspiration and core biopsy under CT fluoroscopy guidance: a better way to treat patients with lung nodules?

OBJECTIVE: The goal of our study was to evaluate the efficacy of the combined use of fine-needle aspiration and tissue core biopsy under real-time CT fluoroscopy guidance. SUBJECTS AND METHODS: One hundred thirty-eight percutaneous needle lung biopsy samples were obtained by two methods. The samples obtained by tissue fine-needle aspiration underwent cytologic evaluation, and those obtained by core biopsy using an automated cutting needle underwent histologic evaluation. The final diagnosis was confirmed by independent surgical pathologic findings, independent culture results, or clinical follow-up. RESULTS: Rates of adequate specimens obtained and of precise diagnosis by combined use of fine-needle aspiration and core biopsy were 97.1% (134/138) and 94.2% (130/138) evaluated lung lesions, respectively, whereas those rates were 84.8% (117/138) and 79.7% (110/138) by fine-needle aspiration alone and 91.3% (126/138) and 89.1% (123/138) by core biopsy alone, respectively. Precise diagnosis was achieved by the combined use of the techniques in 30 (93.8%) of 32 lesions ranging from 3 to 10 mm in diameter, 42 (93.3%) of 45 lesions ranging from 11 to 20 mm, 43 (93.5%) of 46 lesions ranging from 21 to 30 mm, and 100% of 15 lesions ranging from 31 to 100 mm. In 89 of 90 lesions shown to be malignant by CT-guided lung biopsy and 30 of 44 shown to be benign, specific cell types could be proven from specimens obtained by the combined use of the two different types of needle biopsy. CONCLUSION: The combined use of fine-needle aspiration and core biopsy improves the diagnostic ability of CT fluoroscopy-guided lung biopsy, even in small lesions.     

Postmortem evaluation of four randomly selected automated biopsy devices for transthoracic lung biopsy

Purpose To evaluate four automated devices to achieve transthoracic lung biopsy.Methods Transthoracic lung biopsy specimens were obtained randomly from 21 human cadavers with unsuspicious lungs using Biopty (18- and 20-gauge), BIP (18 and 20-gauge), ASAP (18 gauge), and Autovac (18- and 20-gauge) devices. A total of 63 biopsies were carried out with each device and each needle diameter. The same devices and needles were then used randomly for biopsy of peripheral lung metastases. Specimens obtained during both parts of the study were analyzed for the area of tissue on the histologic section, adequacy of tissue for diagnosis, tissue preservation, and crush artifact. The examining pathologist was kept unaware of which procedure was used to obtain the specimens and the cadavers' clinical history.Results The Biopty 18-gauge device performed statistically better than any other of the evaluated systems for biopsy of normal lung parenchyma (p < 0.05). For biopsy of lung metastases, the differences between the devices and needle diameters were less, although the Biopty 18-gauge device performed better than the Autovac 18-gauge, BIP 18-gauge, and all 20-gauge devices for the area of tissue on the histologic section (p < 0.05). The results of the full-cut Autovac biopsy system were remarkable because of the large number of biopsies during which no tissue was obtained.Conclusion Automated biopsy devices can obtain high quality lung specimens sufficient for definite histopathologic diagnosis. However, additional clinical studies on the use of automated biopsy devices for lung biopsy are mandatory.     

门诊病人 X 线定位坐位肺穿刺活检 1316 例的体验

目的：对１３年来（１９８３～１９９５年）１３１６例门诊病人肺穿刺活检的经验总结。方法：病人以Ｘ线定位、坐位、经皮肺穿刺针吸活检。结果：１３１６例肺穿刺１３５０例次，确诊率９５．３％（１２５４／１３１６例次），并发症率４．０７％（５５／１３５０例次），其中气胸３．３３％（４５／１３５０例次），少量咯血０．７４％（１０／１３５０例次），３１．２％的病人避免了不必要的剖胸探查。结论：本法特点：１．方便门诊病人，节省费用，缩短确诊时间。２．坐位穿刺操作简便、灵活、迅速、安全。３．穿刺过程中一般医生和病人不受Ｘ线辐射，除非对小而深的病灶穿刺才透视确保穿中。４．能获取组织和细胞学检查标本。最后笔者对比了本法与其他肺穿刺法的优缺点。     

CT引导肺穿刺活检诊断肺炎型肺癌的价值研究

目的：探讨CT引导肺穿刺活检术诊断肺炎型肺癌的临床价值。方法：搜集26例首诊为炎性病变,后经临床病理证实为肺癌患者的病例资料,将其中确诊前接受了CT引导肺部病变穿刺活检术的19例作为本组研究病例进行回顾性分析。结果：根据CT引导肺部病变穿刺活检物获得病理诊断为腺癌12例,细支气管肺泡癌6例,肺泡上皮乳头状重度异型不典型增生1例（手术证实为乳头状腺癌）。本组病例CT引导肺穿刺活检物病检阳性率为100%。结论：CT引导肺穿刺活检术对明确肺炎型肺癌的诊断有重要价值。     

Ipsilateral decubitus position for percutaneous CT-guided adrenal biopsy

Positioning the patient on the side to be biopsied elevates and relatively immobilizes the diaphragmatic leaf on the dependent side, allowing percutaneous adrenal needle biopsy by a direct posterior approach without traversing lung tissue. The ipsilateral decubitus position was used successfully for biopsy of four small adrenal lesions in which lung precluded a direct posterior approach in the prone position. In addition, the relative stability of the diaphragmatic leaf further facilitated accurate needle placement.