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1.
Lucas Siqueira Pinheiro Júlia Eick Iglesias Daiana Boijink Letícia Boldrin Mestieri Patrícia Maria Poli Kopper José Antônio de Poli Figueiredo Fabiana Soares Grecca 《Journal of endodontics》2018,44(7):1140-1145
Introduction
The aim of this study was to evaluate the cell viability and tissue reaction of NeoMTA Plus (NMP; Avalon Biomed Inc, Houston, TX) compared with mineral trioxide aggregate (MTA; Angelus, Londrina, PR, Brazil) and Biodentine (BD; Septodont, Saint-Maur-de-Fossés, France).Methods
Fibroblasts (3T3) were plated and exposed to 1% extract from the test material before and after setting. Cytotoxicity assessment was performed using the 3-(4,5-dimethyl-thiazoyl)-2,5-diphenyl-tetrazolium bromide and sulforhodamine B assays. In vivo evaluation consisted of polyethylene tube implantation of the materials in rat subcutaneous tissue. Histologic analysis occurred at 7, 30, and 90 days, scoring inflammatory events and collagen fiber formation. Analysis of variance and the Tukey and t tests were used for cytocompatibility assays, and the Kruskal-Wallis test followed by the Dunn test were used for biocompatibility assays (P ≤ .05).Results
The materials in the cytotoxicity assays presented greater viability after setting (P ≤ .05). NMP and MTA presented higher viability than the control (Dulbecco modified Eagle medium) on the 3-(4,5-dimethyl-thiazoyl)-2,5-diphenyl-tetrazolium bromide assay before and after setting (P ≤ .05). The sulforhodamine B assay showed that MTA and BD presented less viability than NMP and the control, and NMP was similar to the control before setting. After setting, MTA and BD presented higher viability when compared with the control group (P ≤ .05), and NMP was similar to control. Inflammatory infiltrate reduction occurred throughout the test periods for all materials. At 7 days, neutrophils were present in BD (P ≤ .05), and granuloma and giant cells were present in BD and MTA. At 30 days, BD showed intense inflammatory infiltrates and a large number of macrophages when compared with NMP, MTA, and the control (P ≤ .05). At 90 days, BD presented a thick fiber layer compared with NMP (P ≤ .05).Conclusions
NMP showed similar biocompatible behavior to MTA and BD. 相似文献2.
Mahya Hasanzade Mohammadjavad Shirani Kelvin I. Afrashtehfar Parisa Naseri Marzieh Alikhasi 《Journal of Evidence》2019,19(3):236-254
PurposeThis study aims to evaluate digital and conventional impressions for full-coverage restorations in terms of marginal and internal discrepancies.Study selectionThe analysis included in vivo and in vitro studies reporting the marginal or internal gap of full-coverage restorations that provide both the conventional and digital impression. The PubMed, Cochrane Trials, and Scopus databases were searched. The quality of clinical trials was rated using Cochrane Collaboration's tool, and the quality of the evidence was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation tool. Heterogeneity among the studies was evaluated, and a meta-analysis with subgroup analysis was conducted whenever it was possible.ResultsThirty-three articles (8 prospective clinical trials and 26 in vitro studies) were selected to extract data after applying the predefined selection criteria. The standard mean difference (SMD) of the meta-analysis for marginal adaptation was ?0.76 (95% confidence interval: ?1.23 to ?0.29) and ?0.59 (95% confidence interval: ?0.93 to ?0.24) for in vitro and in vivo studies, respectively, indicating digital impressions provided significantly less marginal gap than conventional impressions in in vitro studies (P = .002). The impression technique did not significantly influence the internal adaptation.ConclusionsDifferences in marginal adaptation between the digital and conventional groups are not significant for in vivo studies, but for in vitro studies, the digital impression resulted in better marginal adaptation. Based on the Grading of Recommendations, Assessment, Development, and Evaluation approach for marginal adaptation, clinical studies were classified as high confidence and in vitro studies were graded moderate because of the inconsistency. Furthermore, high-quality studies are needed to confirm our results (the International Prospective Register of Systematic Reviews; CRD42017077925). 相似文献
3.
Yoon-Hyuk Huh Eul-Chang Yang Chan-Jin Park Lee-Ra Cho 《The Journal of prosthetic dentistry》2018,119(6):994-999
Statement of problem
The relationship between surface roughness and the optical characteristics of zirconia prostheses may be affected by the type of shaded block.Purpose
The purpose of this in vitro study was to investigate changes in surface roughness and brightness of monolithic zirconia blocks of different shades after polishing.Material and methods
The surface roughness averages of 3 different kinds of shaded zirconia blocks (Zenostarof T0 [T0], Zenostar sun [Ts], and Zenostar sun chroma [Tsc]) were compared after surface polishing. Fifteen specimens of differing thicknesses were produced per block. (1 mm and 3 mm). Surface morphology and compositions were analyzed by using filed emission scanning electron microscopy (FE-SEM) and energy dispersive spectrometry. A 1-way ANOVA and the post hoc Scheffé test were performed (α=.05). The correlations between surface roughness and brightness were determined using the Pearson correlation analysis (α=.01).Results
After phased polishing, Ts had the highest average roughness, followed by T0 and then Tsc. A statistically significant difference in roughness was observed between Ts and Tsc (P<.05). Ts exhibited multiple distinct layers in the FE-SEM image. Carbon was detected in the Ts specimens only. Brightness was highest in T0, followed by Ts and then Tsc. A positive correlation was observed between brightness and surface roughness for all specimens (P<.01). This correlation was stronger in the thicker specimens.Conclusions
The results of this study suggest that polishing affects monolithic zirconia differently depending on shade. The polishing of monolithic zirconia reduces both surface roughness and brightness. The optical properties of monolithic zirconia vary by thickness and can be opaque or translucent. 相似文献4.
Massimo Del Fabbro Kelvin Ian Afrashtehfar Stefano Corbella Ahmed El-Kabbaney Isabella Perondi Silvio Taschieri 《Journal of Evidence》2018,18(1):59-69
Introduction
This systematic review evaluated the effectiveness of nickel-titanium (NiTi) rotary files compared to stainless-steel (SST) hand files.Methods
An electronic search was performed on Medline, EMBASE, CENTRAL and Scopus databases up to February 2016. An additional hand searching was performed in 13 journals. The studies were classified according to study type and the outcome variables. Two reviewers independently applied eligibility criteria, extracted data, and three reviewers independently assessed the quality of the evidence of each included study according to The Cochrane Collaboration's procedures. A meta-analysis was performed whenever it was possible.Results
The electronic and hand search strategies yielded 1155 references of studies after removal of duplicates. Four clinical studies (two prospective and two retrospective studies) and 18 in vitro studies (on extracted teeth) were included for the qualitative synthesis after full-text evaluation of the eligible studies. The overall level of methodological quality of the studies included can be considered inadequate. Only one clinical study was judged at low risk of bias, whereas most non-clinical studies had a low risk of bias. Three meta-analyses, based on a very limited number of studies, could be performed. Each meta-analysis contained two studies. Of these, one meta-analysis was based on clinical studies.Conclusions
The results of this systematic review suggested that NiTi rotary instruments were associated with lower canal transportation and apical extrusion when compared to SST hand files, whereas both groups had similar outcomes in terms of success of therapy, amount of residual bacteria, and cleansing ability after treatment. However, due to the limited evidence available, these results should be interpreted with caution. Consequently, more randomized control trials using standardized protocols are needed in order to provide more solid recommendations. 相似文献5.
Joon-Soo Kim Ji-Hyeon Bae Mi-Jung Yun Jung-Bo Huh 《The Journal of prosthetic dentistry》2017,117(6):775-783
Statement of problem
Recently, zirconia removal diamond rotary instruments have become commercially available for efficient cutting of zirconia. However, research of cutting efficiency and the cutting characteristics of zirconia removal diamond rotary instruments is limited.Purpose
The purpose of this in vitro study was to assess and compare the cutting efficiency, durability, and diamond rotary instrument wear pattern of zirconia diamond removal rotary instruments with those of conventional diamond rotary instruments. In addition, the surface characteristics of the cut zirconia were assessed.Material and methods
Block specimens of 3 mol% yttrium cation-doped tetragonal zirconia polycrystal were machined 10 times for 1 minute each using a high-speed handpiece with 6 types of diamond rotary instrument from 2 manufacturers at a constant force of 2 N (n=5). An electronic scale was used to measure the lost weight after each cut in order to evaluate the cutting efficiency. Field emission scanning electron microscopy was used to evaluate diamond rotary instrument wear patterns and machined zirconia block surface characteristics. Data were statistically analyzed using the Kruskal-Wallis test, followed by the Mann-Whitney U test (α=.05).Results
Zirconia removal fine grit diamond rotary instruments showed cutting efficiency that was reduced compared with conventional fine grit diamond rotary instruments. Diamond grit fracture was the most dominant diamond rotary instrument wear pattern in all groups. All machined zirconia surfaces were primarily subjected to plastic deformation, which is evidence of ductile cutting. Zirconia blocks machined with zirconia removal fine grit diamond rotary instruments showed the least incidence of surface flaws.Conclusions
Although zirconia removal diamond rotary instruments did not show improved cutting efficiency compared with conventional diamond rotary instruments, the machined zirconia surface showed smoother furrows of plastic deformation and fewer surface flaws. 相似文献6.
Dan Wang Ya Shen Jingzhi Ma Robert E.W. Hancock Markus Haapasalo 《Journal of endodontics》2017,43(11):1862-1867
Introduction
The aim of this study was to evaluate the effect of DJK-5, a newly developed cationic antimicrobial peptide, on oral multispecies and Enterococcus faecalis biofilms alone or combined with the endodontic chelating agent EDTA in vitro.Methods
Oral multispecies biofilms from 2 donors and E. faecalis VP3-181 biofilm were grown on collagen-coated hydroxyapatite disks. After incubation for 3 days or 3 weeks, the biofilms were exposed to sterile saline (negative control), 8.5% EDTA, 2% chlorhexidine digluconate (CHX), 5 μg/mL DJK-5, 10 μg/mL DJK-5, a mixture of 5 μg/mL DJK-5 and 8.5% EDTA (final concentration), or a mixture of 10 μg/mL DJK-5 and 8.5% EDTA, all for 1 and 3 minutes. The proportions of dead bacteria in the biofilms were assessed by the LIVE/DEAD staining (Thermo Fisher Scientific, Waltham, MA) and confocal microscopy.Results
The peptide DJK-5 rapidly killed most bacteria in all biofilms, with significant differences to the control, 8.5% EDTA and 2% CHX (P < .01). Basically, a higher DJK-5 concentration and longer exposure (3 minutes) were more effective than a low concentration and short time exposure (P < .05). There were no significant differences in antibiofilm activities between DJK-5 used alone or in the mixture with 8.5% EDTA at either concentration. EDTA (8.5%) had no significant antimicrobial effect compared with the negative control (P > .05), but, unlike DJK-5 alone, the mixture retained the ability to remove smear layers. In peptide groups, there were no significant differences in dead bacteria proportions between 3-day and 3-week biofilms, except for 10 μg/mL DJK-5 used alone for 3 minutes on the multispecies biofilms.Conclusions
DJK-5 exerted antibiofilm ability on E. faecalis and oral multispecies biofilms grown on hydroxyapatite disks, both alone and when combined with 8.5% EDTA. 相似文献7.
Introduction
The aim of this study was to evaluate the changes in the surface profile of rotary nickel-titanium (NiTi) files designed to prepare a glide path and conventional stainless steel (SS) hand files when used in extremely narrow canals both in clinical and experimental conditions.Methods
This ex vivo/in vivo study used either SS #10 K hand files or the PathFile system (Dentsply Maillefer, Ballaigues, Switzerland) to establish a glide path in maxillary molars with narrow root canals (defined as canals that bound a #8 K-file at the working length). After treatment, all files were cleaned and scanned using a noncontact laser profilometer. Changes to the surface profile (Ra cutting edge waviness = RaCEW) and roughness (Ra cutting edge roughness = RaCER) of the cutting edges and the surface roughness of the flute area (Sa flute roughness = SaFR) were analyzed.Results
#10 K-files had significant increases in all types of measurements (RaCEW, RaCEW, and SaFR) after the preparation of second mesiobuccal canals compared with the control group (P < .05) in both studies. In the ex vivo study, the PathFile (P1) had no significant changes in the surface profile from baseline but had a significant increase in the surface roughness of the flute (SaFR) (P < .05). PathFiles that were used 3 times in vivo had a significant increase in roughness (flute and cutting edge) values across all PathFile sizes compared with control values.Conclusions
This study showed that PathFiles had significantly less surface defects compared with SS files after the preparation of narrow canals, indicating their possible benefits when establishing a glide path in extremely narrow canals. 相似文献8.
9.
Filip Koneski Danica Popovic-Monevska Icko Gjorgoski Jovanka Krajoska Mirjana Popovska Ilijana Muratovska Boris Velickovski Gordana Petrushevska Vladimir Popovski 《Journal of cranio-maxillo-facial surgery》2018,46(2):230-236
Background
Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a complication of the bisphosphonate (BP) treatment and its pathopysiology is still not fully understood. The existing preventive and treatment options require updates and more attention. Geranylgeraniol (GGOH) so far demonstrated an increased activity and viability of the cells previously treated with zoledronic acid (ZA). The aim of this study was to evaluate the in vivo effects of GGOH on the development of BRONJ.Materials and methods
A total of 30 male Wistar rats were included in the study, divided into three groups: two experimental groups (EG1 and EG2) and a control group (CG). Rats from EG1 and EG2 were treated with 0,06 mg/kg ZA ip weekly in a duration of five weeks, while CG received saline ip. On the third week all animals underwent extraction of the lower right first molars. The rats from EG2 received a local solution of GGOH in concentration of 5 mM in the socket every day after the tooth extraction. The analyses included clinical evaluation on the wound healing and pathohistological evaluation for presence and level of osteonecrosis.Results
EG2 showed significantly improved wound healing and tissue proliferation, when compared to EG1. EG2 significantly differed from EG1 and CG (p<0,05) for the presence of microscopical osteonecrosis (80% vs 22,2% vs 0%). Regarding to the number of empty lacunes without osteocytes and the level of necrosis, all groups demonstrated significant differences.Conclusion
Geranylgeraniol in a form of local solution may be a promising option for prevention and treatment of BRONJ. 相似文献10.
Wolfgang Bömicke Moritz Waldecker Johannes Krisam Peter Rammelsberg Stefan Rues 《The Journal of prosthetic dentistry》2018,119(1):89-96
Statement of problem
The clinical use of ceramic resin-bonded fixed dental prostheses (RBFDPs) in the posterior region is desirable for esthetic and biological reasons but has been associated with many technical problems, including fractures or chipping of the veneer. Although these problems may be overcome by using monolithic zirconia, information is lacking about the load-bearing capacity of resin-bonded monolithic zirconia restorations for replacing a molar.Purpose
The purpose of this in vitro study was to compare the load-bearing capacity (Fu), the load at initial damage (F1d), and the failure pattern of posterior RBFDPs fabricated from monolithic zirconia (MZr), veneered zirconia (VZr), and veneered cobalt-chromium (VCo).Material and methods
For the replacement of a maxillary first molar, 4 groups (n=8) of RBFDPs differing in prosthesis material and retainer design (MZr-IR-RBFDPs, VZr-IR-RBFDPs, MZr-WR-RBFDPs, and VCo-WR-RBFDPs; IR, inlay-retained; WR, adhesive wing-retained) were fabricated with anatomic congruence of the FDP-abutment complex. The RBFDPs were subjected to thermocycling (10 000×6.5°C/60°C) and mastication simulation (30-degree oblique loading on the pontic; 1 200 000×108 N) and then loaded until failure in a universal testing machine (0.5 mm/minute). Test forces correlating with Fu and F1d were recorded. Statistical analysis was performed by using 2-way analysis of variance (ANOVA), 2-way repeated measures ANOVA, and the Tukey honest significant differences post hoc test (2-sided α=.05).Results
Fu was significantly affected by retainer design (P<.001) and F1d by both retainer design (P<.001) and prosthesis material (P<.001). Fu was more than 2000 N for WR-RBFDPs and more than 1000 N for IR-RBFDPs (Tukey test ranking: MZr-WR-RBFDPs = VCo-WR-RBFDPs > MZr-IR-RBFDPs = VZr-IR-RBFDPs). Ceramic RBFDPs failed by complete fracture in the connector region, whereas failure of VCo-WR-RBFDPs was limited to the ceramic veneer. F1d was significantly lower (P≤.004) than Fu for veneered specimens only; F1d started at test forces below 500 N and coincided with veneer cracking.Conclusions
Load-bearing capacity suitable for the definitive restoration of a molar was observed for all groups. Veneered resin-bonded fixed dental prostheses, however, were susceptible to cracking of the veneer. 相似文献11.
Introduction
This study compared the effects of different mixing and placement techniques on sealing of ProRoot MTA (Dentsply Maillefer, Ballaigues, Switzerland) and MTA Angelus (Soluçoes Odontologicas, Londrina, Brazil) apical plugs using micro–computed tomographic (micro-CT) imaging.Methods
Standardized divergent open apex models were created using 120 extracted maxillary incisors and divided into 8 groups (n = 15). ProRoot MTA and MTA Angelus were mixed manually or mechanically and introduced to form apical plugs by hand condensation or indirect ultrasonic activation for 10 seconds. The samples were scanned using micro-CT imaging, and volumetric analysis of the voids between the dentin walls and the apical plugs and the porosity inside MTA was performed.Results
Irrespective of the mixing and placement techniques used, the voids between the dentin walls and the apical plugs in the MTA Angelus groups were greater than those in the ProRoot MTA groups (P < .05). The mechanically mixed groups were significantly less porous than the manually mixed groups (P < .05). Combined mechanical mixing and indirect ultrasonic activation yielded a less porous structure for both types of MTA than combined manual mixing and hand condensation (P < .05). Marginal adaptation for ProRoot MTA, both mixed and placed manually, was greater than for MTA Angelus (P < .05), but no difference was found when indirect ultrasonic activation was performed (P > .05).Conclusions
ProRoot MTA showed better marginal adaptation than MTA Angelus. Mechanically mixed products had better handling characteristics than the manually mixed product. Indirect ultrasonic activation did improve the adaptation of manually mixed MTA Angelus to the dentin walls. 相似文献12.
Statement of problem
Because of their relatively small scanning area, intraoral scanners may result in less accurate fixed dental prostheses (FDPs) than do laboratory scanners.Purpose
The purpose of this in vitro study was to evaluate the accuracy of monolithic zirconia FDPs with different numbers of pontics fabricated with different impression techniques.Material and methods
The mandibular right premolars and molars of an acrylic resin model were prepared to receive 4-unit FDPs. Three master models were fabricated with epoxy resin: model NP, no pontic; model 1P, 1 pontic; and model 2P, 2 pontics. Each master model was scanned by using direct (DD) and indirect digitalization (ID). Four-unit monolithic zirconia FDPs were fabricated and divided into 3 groups (groups NP, 1P, and 2P) and then subdivided according to the digitalization technique (group DD and ID; n=10). The FDPs were also evaluated based on the presence (Po) or absence (NPo) of an adjacent pontic. The marginal, axial, and occlusal gap widths of each FDP were measured, and statistical analyses were performed to evaluate and compare the amount of gap present (α=.05).Results
For direct digitalization, group 2P had significantly greater marginal (69.4 μm versus 60.9 μm or 62.3 μm; P<.001) and axial gap widths (127.1 μm versus 108.9 μm or 110.4 μm; P<.001) than group NP or 1P. Group DD resulted in significantly smaller gaps compared with group ID at marginal (64.8 μm versus 73.6 μm), axial (114.8 μm versus 124.3 μm), and occlusal (172.6 μm versus 184.1 μm) measurement locations (P<.001). Greater marginal and axial gaps were noted in group Po than NPo (P<.001).Conclusions
The length of the edentulous area significantly influenced the extent of the marginal and internal gap with the use of direct digitalization. Direct digitalization resulted in significantly smaller gap widths in all measurement areas than indirect digitalization; however, the mean differences were less than 12 μm, which is considered clinically insignificant. The presence of an adjacent pontic had a significant effect on the adjacent marginal and axial gap widths. 相似文献13.
Hadi AL-Meraikhi Burak Yilmaz Edwin McGlumphy William Brantley William M. Johnston 《The Journal of prosthetic dentistry》2018,119(3):409-416
Statement of problem
Computer-aided designed and computer-aided manufactured (CAD-CAM) titanium and zirconia implant-supported fixed implant prostheses on 4 implants have become popular. The precision and accuracy of their interface fit has not been widely researched.Purpose
The purpose of this in vitro study was to compare the marginal fit of zirconia and titanium implant-supported screw-retained CAD-CAM complete fixed dental prostheses (CFDP) fit with a standardized cast simulating the all-on-4 implant distribution.Material and methods
Representation of an edentulous maxilla with 4 multiunit replicas embedded in sites corresponding to the positions of the maxillary first molars and canines was chosen. Multiunit abutments were digitally scanned using scan bodies and a laboratory scanner. CAD software was used to design screw-retained implant-fixed complete prostheses framework, and the file was sent to a milling machine for CAM. Titanium (n=5) and zirconia (n=5) frameworks were milled on 4 implants, and the frameworks were scanned with an industrial computed tomography (CT) scanner while applying the 1-screw test. The direct CT scans were reconstructed to generate a standard tessellation language (STL) file from the voxel data set and transported to volume graphics analysis software from which measurements were extracted. The circular mating surfaces of the corresponding framework interfaces to their representative multiunit abutment replicas on the standard were measured for implant position left maxillary canine (LMC), implant position right maxillary canine (RMC) and implant position right maxillary first molar (RMFM). In addition, color maps were generated to show the marginal discrepancy between the mating surfaces using ±0.500 mm color scale ranges.Results
The material type (zirconia or titanium) was not significant for 3D discrepancy measurements (P=.904). However, 3D discrepancy measurement values were significantly different between RMC and RMFM within each group (P<.001). The mean 3D ±SD discrepancy measurement for LMC for titanium was 48.2 ±2.6 μm. The mean ±3D discrepancy measurement for RMC for titanium was 74 ±15 μm and 84.4 ±12.1 μm for zirconia. The mean 3D discrepancy measurement for RMFM for titanium was 102 ±26.7 μm and 93.8 ±30 μm for zirconia. All 3D discrepancy measurements showed values <135 μm.Conclusions
Within the limitations of the present in vitro study, implant-supported CAD-CAM fabricated titanium and zirconia complete fixed dental prosthesis frameworks showed comparable marginal fit. Three-dimensional microgap measurements of frameworks showed clinically acceptable misfit values. Absolute passive fit was not achieved. 相似文献14.
Thomas Giraud Charlotte Jeanneau Madison Bergmann Patrick Laurent Imad About 《Journal of endodontics》2018,44(11):1686-1691
Introduction
On stimulation by lipoteichoic acid or by a physical injury, fibroblasts have been shown to play a major role in the initiation of the pulp inflammatory reaction and healing through secretion of complement proteins and growth factors. The application of direct pulp-capping materials on these cells may interfere with the inflammatory and the healing processes within the pulp's inextensible environment. This work was designed to study in vitro the effects of silicate-based materials on pulp fibroblast modulation of the initial steps of pulp inflammation and healing.Methods
The effects of Biodentine, TheraCal, and Xeno III eluates were studied on lipoteichoic acid–stimulated and physically injured fibroblasts. Cytokine secretion (interleukin 6, vascular endothelial growth factor, fibroblast growth factor-2, and transforming growth factor-β1) was quantified by enzyme-linked immunosorbent assay. Inflammatory THP-1 adhesion to endothelial cells and their migration and activation were studied in vitro. Human pulp fibroblast proliferation was investigated with the MTT test, and their migration to the injury site was studied with the scratch healing assay.Results
Interleukin 6 and vascular endothelial growth factor secretion increased with all materials but to a lesser extent with Biodentine. Fibroblast growth factor-2 and transforming growth factor-β1 secretion was significantly higher with Biodentine than with all other materials. THP-1 cell adhesion to endothelial cells and their activation were reduced by Biodentine and TheraCal. However, their migration decreased only with Biodentine. Fibroblast proliferation significantly increased with Biodentine but significantly decreased with Xeno III after day 6. Finally, only Biodentine induced fibroblast migration to the injury site in the scratch assay.Conclusions
These results confirm that pulp-capping materials affect the early steps of pulp inflammation and healing. They show that Biodentine had the highest pulp healing and anti-inflammatory potential when compared with the resin-containing materials. This highlights the interest of the material choice for direct pulp-capping. 相似文献15.
Nereu Roque Dartora Michele Bertoluzi de Conto Ferreira Izabela Cristina Maurício Moris Elisabeth Helena Brazão Aloísio Oro Spazin Manoel Damião Sousa-Neto Yara Terezinha Silva-Sousa Erica Alves Gomes 《Journal of endodontics》2018,44(7):1179-1185
Introduction
Endodontically treated teeth have an increased risk of biomechanical failure because of significant loss of tooth structure. The biomechanical behavior of endodontically treated teeth restored was evaluated using different extensions of endocrowns inside the pulp chamber by in vitro and 3-dimensional finite element analysis (FEA).Methods
Thirty mandibular human molars were endodontically treated. Standardized endocrown preparations were performed, and the teeth were randomly divided into 3 groups (n = 10) according to different endocrown extensions inside the pulp chamber: G-5 mm, a 5-mm extension; G-3 mm, a 3-mm extension; and G-1 mm, a 1-mm extension. After adhesive cementation, all specimens were subjected to thermocycling and dynamic loading. The survival specimens were subjected to fracture resistance testing at a crosshead speed of 1 mm/min in a universal testing machine. All fractured specimens were subjected to fractography. Data were analyzed by 1-way analysis of variance and the Tukey post hoc test (P < .05). Stress distribution patterns in each group were analyzed using FEA. Qualitative analyses were performed according to the von Mises criterion.Results
After dynamic loading, a survival rate of 100% was observed in all groups. For static loading, statistically significant differences among the groups were observed (P < .05) (G-5 mm = 2008.61 N, G-3 mm = 1795.41 N, and G-1 mm = 1268.12 N). Fractography showed a higher frequency of compression curls for G-5 mm and G-3 mm than for G-1 mm. FEA explained the results of fracture strength testing and fractography.Conclusions
Greater extension of endocrowns inside the pulp chamber provided better mechanical performance. 相似文献16.
Annie Shrestha Shimon Friedman Calvin D. Torneck Anil Kishen 《Journal of endodontics》2018,44(1):104-110
Introduction
The persistence of dentin-bound lipopolysaccharides (LPS) in disinfected root canals impedes treatment outcomes of endodontic procedures. This study assessed the effects of photoactivated rose bengal–functionalized chitosan nanoparticles (CSRBnps) on LPS-contaminated root dentin in vivo using an intraosseous implantation model and neotissue formation as a marker.Methods
Fifty human, 3-mm-long root segments with a 1.2-mm canal lumen were divided into 5 groups (n?=?10): group 1, canals not contaminated; group 2, canals contaminated with Pseudomonas aeruginosa LPS; group 3, canals contaminated and disinfected with sodium hypochlorite (NaOCl); group 4, canals contaminated and disinfected with NaOCl and calcium hydroxide; and group 5, canals contaminated and disinfected with NaOCl and CSRBnps (300?μg/mL) with photoactivation (λ?=?540?nm, 40?J/cm2). Specimens were implanted into mandibles of guinea pigs, block dissected after 4?weeks, and the canal content evaluated histologically and immunohistochemically. The ingrown neotissue interface (50?μm) with dentin was characterized for fibroblasts, osteoclasts, inflammatory markers, dentin resorption, mineralization, and angiogenesis and dichotomized as type 1 (no inflammation and resorption, indicative of LPS inactivation) or type 2 (inflammation and resorption). The frequency of the observed parameters was analyzed using the Fisher exact test.Results
The outcome was categorized as type 1 in groups 1 and 5, type 2 in group 2, and mixed type 1 and 2 in groups 3 and 4. The outcomes in groups 1 and 5 (P?>?.05) differed significantly (P?<?.05) from those in groups 2, 3, and 4.Conclusions
Disinfection of LPS-contaminated root canals with photoactivated CSRBnps in vivo supported ingrowth of neotissue without signs of inflammation or resorption, suggestive of effective inactivation of dentin-bound LPS. 相似文献17.
18.
K. Siva sankar K. Pranitha A.J. Sai Sankar B. Sujatha V. Sai krishna K. Kiran kumar 《Pediatric Dental Journal》2018,28(3):160-164
Background
Remineralizing agents are found to be effective in the remineralization of early enamel caries and the remineralized enamel crystallites are more resistant to decalcification and also have the same orientation as the original enamel crystallites. Although child formula fluoridated dentifrices are used safely by young children their remineralizing capability remains questionable.Aim
To evaluate the remineralizing potential of three commercially available pediatric dentifrices on artificial carious lesions in primary teeth.Materials and methods
A total of fifty sound human primary teeth were coated with nail varnish leaving a window of 2 mm × 4 mm on buccal surface and were subjected to demineralization for a period of 96 h and then sectioned. Out of the hundred sections obtained, ninety sections are equally divided into three groups with thirty in each group: Group I (Colgate Spider man), Group II (Kids bunny), Group III (Kidodent) subjected to remineralization respectively for 10 days using pH cycling model. The sections were then evaluated under the stereomicroscope for the remineralization values using MICAP image analyser software.Results
Statistical analysis was done by using ANOVA test which showed that all the three dentifrices showed remineralization with artificial carious lesions. Among the three test groups, Group I showed higher remineralization potential compared with the other two pediatric dentifrices which was statistically significant (p < 0.05).Conclusion
All the three dentifrices demonstrated remineralization of carious lesions by virtue of decrease in lesion depth. 相似文献19.
Statement of problem
Dental laboratories use different computer-aided design and computer-aided manufacturing (CAD-CAM) systems to fabricate fixed prostheses; however, limited evidence is available concerning which system provides the best marginal discrepancy.Purpose
The purpose of this in vitro study was to evaluate the marginal fit of 5 different monolithic zirconia restorations milled with different CAD-CAM systems.Material and methods
Thirty monolithic zirconia crowns were fabricated on a custom-designed stainless steel die and were divided into 5 groups according to the type of monolithic zirconia crown and the CAD-CAM system used: group TZ, milled with an MCXL milling machine; group CZ, translucent zirconia milled with a motion milling machine; group ZZ, zirconia milled with a dental milling unit; group PZ, translucent zirconia milled with a zirconia milling unit; and group BZ, solid zirconia milled using an S1 VHF milling machine. The marginal fit was measured with a binocular microscope at an original magnification of ×100. The results were tabulated and statistically analyzed with 1-way ANOVA and post hoc surface range test, and pairwise multiple comparisons were made using Bonferroni correction (α=.05).Results
The type of CAD-CAM used affected the marginal fit of the monolithic restoration. The mean (±SD) highest marginal discrepancy was recorded in group TZI at 39.3 ±2.3 μm, while the least mean marginal discrepancy was recorded in group IZ (22.8 ±8.9 μm). The Bonferroni post hoc test showed that group TZI was significantly different from all other groups tested (P<.05).Conclusions
Within the limitation of this in vitro study, all tested CAD-CAM systems produced monolithic zirconia restorations with clinically acceptable marginal discrepancies; however, the CAD-CAM system with the 5-axis milling unit produced the best marginal fit. 相似文献20.
Shinji Yoshii Masataka Fujimoto Masahiro Okuda Chiaki Kitamura 《Journal of endodontics》2018,44(12):1856-1861