胶原蛋白海绵预防干槽症效果观察

目的:观察胶原蛋白海绵预防下颌第三磨牙阻生拔除术后干槽症的效果.方法:选取120例下颌第三磨牙阻生需要拔除的患者,随机分为观察组和对照组,各60例,观察组术后将胶原蛋白海绵放入拔牙窝内,对照组常规处理拔牙创,不放置任何药物,术后随访,观察比较干槽症的发生率.结果:观察组干槽症发生率(1/60,1.7％)低于对照组(8/60,13.3％),有统计学意义(P＜0.05).结论:阻生牙拔除后拔牙创内放置胶原蛋白海绵可有效预防干槽症的发生.     

氯己定复合明胶海绵预防下颌阻生智齿拔除术后干槽症的研究

目的 观察氯己定复合明胶海绵预防下颌阻生智齿拔除术后干槽症的效果.方法 将465例拔除下颌阻生智齿的患者随机分为两组.实验组(241例)拔牙后用0.12％的氯己定溶液冲洗拔牙窝,然后填塞入0.12％的氯己定浸泡过的明胶海绵;对照组(224例)拔牙后仅用0.12％的氯己定溶液冲洗拔牙窝.结果 实验组干槽症发生率为0.82％,对照组为4.02％,两者比较有统计学意义()x2 =5.11,P＜0.05).结论 下颌阻生智齿拔除术后拔牙窝内填塞0.12％的氯己定浸泡过的明胶海绵能有效地预防干槽症的发生.     

复方碘仿海绵联合封闭术在下颌阻生智齿拔除术中的应用

目的探讨拔牙创内放置复方碘仿海绵以及局部封闭对预防下颌阻生第三磨牙拔除术后并发症的有效性。方法实验组280颗下颌阻生智齿拔除术后置入复方碘仿海绵于牙槽窝内,术后第1天、第3天、第7天复诊观察术后出血,肿胀,疼痛及干槽症等并发症发生情况。与对照组280颗并发症发生情况进行比较。结果两组比较,实验组在拔牙术后出血,肿胀,疼痛及干槽症方面均有显著性差异。结论复方碘仿海绵联合局部封闭能有效地预防下颌阻生智齿拔除术后并发症。     

替硝唑—碘仿明胶海绵预防干槽症的临床研究

目的 评价替硝唑-碘仿明胶海绵置入下颌阻生智齿拔牙创预防术后干槽症(DS)的效果.方法 选择210例拔除阻生牙患者,术后随机分为两组,每组105例.实验组向牙槽窝中置入替硝唑-碘仿明胶海绵.对照组为空白对照.观察两组术后干槽症的发生率.结果 实验组和对照组干槽症的发生率分别为0.96%和6.67%.两组间有显著性差异(P＜0.05).结论 替硝唑-碘仿明胶海绵置入拔牙创能有效预防下颌阻生智齿拔除术后干槽症的发生.     

三种拔牙窝处理方式预防下颌中低位阻生智齿拔除术后并发症的比较

目的：对比分析三种不同拔牙窝处理方式在预防下颌中低位阻生第三磨牙拔除术后并发症中的临床效果。方法：回顾性分析2016年2月—2022年2月182例在我院拔除下颌中低位阻生第三磨牙患者的病历资料，按照拔牙窝处理方式的不同分为三组。A组(60例):盐酸米诺环素软膏可吸收明胶海绵填充，B组(62例):可吸收明胶海绵填充，C组(60例):不放置任何填充材料。比较三组患者术后24h、72h面部肿胀程度，以及术后出血、拔牙创感染、干槽症三种并发症的总发生率。结果：术后24h面部肿胀程度A组0.05);A组术后出血、拔牙创感染、干槽症术后并发症总发生率均低于B组和C组，且B组低于C组，差异均具有统计学意义(P<0.05)。结论：拔牙窝盐酸米诺环素软膏可吸收明胶海绵填充方案可有效降低下颌中低位阻生第三磨牙拔除患者术后面部肿胀程度，预防术后出血、拔牙创感染、干槽症等并发症...     

360例下颌阻生智齿拔除方法的临床研究

目的:探讨下颌阻生智齿拔除方法、加强术前术后局部处理预防术后并发症的方法.方法:将360例拔除下颌阻生第三磨牙的患者随机分成两组,实验组拔牙术前进行术区洁治及冲洗上药,术中用裂钻切牙去骨法,术后拔牙创内放入碘仿明胶海绵.对照组术前生理盐水漱口,用传统的凿、劈开法,术后拔牙创内不放入任何药物.术后1周进行随访,记录术后出血、肿胀、疼痛、张口受限及干槽症情况,对其进行χ2检验.结果:实验组和对照组间差异均有统计学意义(P<0.05).实验组的拔牙术后并发症明显少于对照组.结论:用裂钻切牙去骨法,加强术前术后局部处理可有效预防下颌阻生智齿拔除术后并发症.     

甲硝唑强的松粉预防干槽症的临床观察

[目的]观察下颌阻生齿拔除后局部应用甲硝唑强的松粉预防干槽症的效果。[方法]选择下颌第三磨牙因阻生需要拔除的患牙100颗,随机分为放药观察组50颗,不放药对照组50颗。观察组拔牙后于拔牙窝内置入甲硝唑强的松粉,然后咬纱球,对照组只常规咬纱球。[结果]观察组50颗阻生齿拔除后无一例发生干槽症,而对照组50颗阻生齿拔除后有6颗发生干槽症,发生率12%,经统计学分析,两组比较有显著性差异(P<0.05)。[结论]甲硝唑强的松粉局部用于下颌阻生齿拔除术后可有效预防干槽症的发生。     

高速涡轮牙钻法拔除下颌阻生智齿临床效果观察

目的 探讨应用高速涡轮牙钻法拔除下颌阻生智齿的临床疗效.方法 298例下颌阻生智齿患者随机采用高速涡轮牙钻法(实验组)和劈冠凿骨法(对照组)拔除下颌阻生智齿,进行临床观察,对比两组平均拔除时间及术后肿胀、疼痛、张口受限、出血、干槽症等并发症发生情况.结果 实验组与对照组患者下颌阻生智齿分布比较,差异无统计学意义(P＞0.05).实验组患者下颌阻生智齿平均拔除时间较对照组明显缩短,差异有统计学意义(P＜0.05).实验组术后肿胀、疼痛、张口受限、出血、干槽症等并发症发生率较对照组明显降低,差异有统计学意义(P＜0.05).结论 高速涡轮牙钻法能显著缩短手术时间,减少患者术后并发症,值得临床推广.     

漱口液对下颌阻生智齿拔除后预防干槽症的临床观察

目的：观察拔牙前漱口液应用后对下颌阻生智齿术后预防干槽症的临床效果。方法：120例下颌阻生智齿拔除术患者随机分为两组,一组60例手术前含漱复方氯已定2分钟,再常规消毒后拔牙,为应用组;另一组60例术前常规消毒后拔牙,为对照组。结果：应用组发生率为1．6％,对照组组为8．3％,两组间比较差异有统计学意义（P＜0．05）。结论：下颌智齿拔牙前应用漱口液能有效预防干槽症的发生。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.