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1.
Juan WANG Yan LI Xuan ZHANG Mei-na WANG Long CAO Na NU Yuan LI Gui-lan LI 《世界针灸杂志》2018,28(4):287-290
Objective
To observe the clinical effects on simple obesity treated with the combined therapy of penetration needling, flash-fire cupping method and auricular acupuncture.Methods
In 90 patients of simple obesity, the Bo's abdominal acupuncture therapy was adopted. Taking Shénquè (神阙 CV 8), the points 2 cun directly below CV 8 and 2 cun directly above CV 8 as the landmarks, 3 cun bilateral to each of the above three points, and penetrated through to the conception vessel. Then the electroacupuncture apparatus was connected, with the disperse-dense wave for 30?min. After acupuncture, the glass cup of the middle size was used to stimulate the selected points with the flash-fire cupping method. The cupping stimulation stopped when the skin turned to be slightly red. One treatment was given each day and every other day after 5 days. The 10 treatments made one course. In the auricular acupuncture therapy, Jīdi?n (饥点), Shénmén (神门TF4), Nèifēnmì (内分泌CO18) and Sānjiāo (三焦 CO17) were selected. The auricular acupuncture therapy was given once every two days and 10 treatments made one course. After 3 courses of treatment, the waist circumference, hip circumference, body weight and body mass index (BMI) were observed.Results
Compared to before treatment, after 3 courses of treatment, the waist circumference of patients was (92.3?±?2.4?vs 80.4?±?2.3) cm, hip circumference (110.6?±?2.3?vs 99.2?±?2.5) cm, body weight (74.2?±?3.1?vs 68.2?±?2.4) kg and BMI (29.8?±?3.1?vs 25.2?±?2.1), they were all reduced obviously, indicating the significant differences (all P?<?0.05). Seventy-nine patients lost three to five kilograms, accounting for 87.8%.Conclusion
The combined therapy of penetration needling at abdomen, flash-fire cupping method and auricular acupuncture achieves the significant therapeutic effects on simple obesity. 相似文献2.
Objective
To evaluate the effect of distal point selection, local point selection, and distal-local point selection on acupuncture efficacy.Methods
According to the requirements of evidence-based medicine (EBM), the literature on acupuncture with distal and local point selection in recent 20 years included in domestic and overseas medical databases was retrieved, and meta-analysis of the included articles was carried out.Results
Thirty-two articles were included finally, totaling 2829 patients. The results of meta-analysis indicated that the curative effect of distal-local point combination was superior to that of simple distal point selection or local point selection during acupuncture–moxibustion treatment for diseases, and there was no obvious difference in the curative effect between simple distal point selection and local point selection. According to the comprehensive analysis of 18 included articles, the difference in total effective rate between distal point selection and local point selection was not statistically significant, i.e. the curative effect of distal point selection and local point selection was equivalent [OR?=?0.83, 95%CI (0.83,1.18), Z?=?1.04, P?>?0.01]. According to the comprehensive analysis of 20 included articles, the difference in total effective rate between local point selection and distal-local point selection was statistically significant, and the results indicated that the curative effect of distal-local point selection was superior to that of local point selection [OR?=?0.32, 95%CI (0.23,0.44), Z?=?6.90, P?<?0.01]. According to the comprehensive analysis of 8 included articles, the difference in total effective rate between distal point selection and distal-local point selection was statistically significant, and the results indicated that the curative effect of distal-local point selection was superior to that of distal point selection [OR?=?0.20, 95%CI (0.10,0.40), Z?=?4.50, P?<?0.01]. In addition, the analysis of publication bias of this study indicated that publication bias might exist. Since the quality of included articles was generally lower, the above conclusion still needed to be supported by more evidence-based medicine proofs with high quality.Conclusion
The curative effect of distal-local point combination was superior to that of simple distal point selection or local point selection during acupuncture treatment for diseases, and there was no obvious difference in the curative effect between simple distal point selection and local point selection. 相似文献3.
Xuan-ping ZHANG Xiao-fei LI Liang QIN Bo-hao HU Chun-sheng JIA Hai-jiao XING 《世界针灸杂志》2018,28(3):209-212
Objective
To explore the rules of the second metacarpal bone lateral needling in clinical application and its characteristics so as to provide the guidance to clinical practice.Methods
Taking “the second metacarpal holographic acupuncture therapy” “the second metacarpal bone lateral needling” and “the second metacarpal bone” as the search terms, the papers on the second metacarpal bone lateral needling were retrieved from China National Knowledge Infrastructure (CNKI) and Wanfang database from January 1, 1974 to December 31, 2016 and were screened. Using the Excel 2003, the database of the diseases treated by the second metacarpal bone lateral needling was set up. The indications, the acupoints selection rules and needling manipulation of this therapy were analyzed.Results
A total of 1103 papers were retrieved, of which, 446 papers were from CNKI and 657 from Wanfang database. According to the inclusion and exclusion criteria, 54 papers were included for analysis finally. It was found that the indications of the second metacarpal bone lateral needling were predominated by the soft tissue injuries, especially acute lumbar sprain, ankle sprain and knee joint injury. Regarding the acupoints selection rules of the second metacarpal bone lateral needling, the corresponding points and tender points were commonly selected. Regarding the needling manipulation, the strong stimulation was required after needle insertion and the patient was required to move the affected areas while keeping the strong needling sensation. The needles were inserted 20?mm in depth along the skin mainly. The even-needling technique was exerted and the needles were retained for 30?min mainly.Conclusion
The second metacarpal bone lateral needling is applied to the treatment of soft tissue injuries. It is applicable for some internal diseases. The strong needling sensation and the motion of the local affected area are required especially in treatment with this therapy. 相似文献4.
Objective
To observe the clinical efficacy of warm needling moxibustion plus flash cupping for remission-stage peripheral facial paralysis (FP) due to wind-cold.Methods
Fifty eligible patients were randomized into a warm needling moxibustion group and an acupuncture-cupping group, 25 cases in each group. The warm needling moxibustion group was intervened by acupuncture at Fengchi (GB 20), Yangbai (GB 14) towards Yuyao (EX-HN 4), Xiaguan (ST 7), Dicang (ST 4) towards Jiache (ST 6), Quanliao (SI 18), and Hegu (LI 4), plus warm needling moxibustion at Quanliao (SI 18); the acupuncture-cupping group received flash cupping on the affected side in addition to the intervention given to the warm needling moxibustion group. The two groups were both treated once a day, 10 times as a treatment course, for 3 courses in total. The House-Brackmann (H-B) facial nerve grading system was observed before and after the intervention to evaluate the facial nerve function in the two groups, and the therapeutic efficacies were also compared between the two groups.Results
The two treatment protocols both can promote the recovery of facial nerve function. The total effective rate was 92.0% in the acupuncture-cupping group versus 72.0% in the warm needling moxibustion group, and the between-group difference was statistically significant (P<0.05).Conclusion
Warm needling moxibustion plus flash cupping can produce a more significant efficacy than dry warm needling moxibustion in treating remission-stage peripheral FP due to wind-cold.5.
Objective
To observe the clinical therapeutic effects on acne treated with the combined therapy of acupuncture, cupping and circling moxibustion.Methods
At the ratio of 4:3, a total of 70 patients were randomized into an acupuncture-cupping group (40 cases) and a western medication group (30 cases). In the acupuncture-cupping group, acupuncture was used in combination with cupping and circling moxibustion. The therapy was given once every other day for totally 30 days. In the western medication group, the routine medication of minocyline capsules was prescribed, 2 times per day and 30 days were in total.Results
After the treatment, the total effective rates were 95.00% and 76.67% in the acupuncture-cupping group and the western medicine group respectively, indicating the significant difference in statistic (P?<?0.05). In the acupuncture-cupping group, the therapeutic effect was the best for the cases differentiated as heat accumulation in the lung and stomach and the total effective rate was 100%. It was 71.43% for the type of damp-heat of the intestine and stomach and was 70.00% for phlegm-damp stagnation.Conclusion
Acupuncture combined with cupping and circling moxibustion achieves the superior clinical therapeutic effects as compared with minocyline. This therapy deserves to be promoted in clinical practice. 相似文献6.
Juanping GOU 《世界针灸杂志》2018,28(1):66-67
Objective
To observe the clinical efficacy of acupuncture combined with cupping therapy for intractable hiccup.Methods
Thirty patients with intractable hiccup were treated by adopting acupuncture combined with cupping therapy. Acupuncture was performed at Cuánzhú (攒竹BL 2), Nèiguān (内关PC 6), Zhōngw?n (中脘CV 12) and Zúsānl? (足三里ST 36), with the time of needle retention for 30?min. Flash cupping was carried out on Fèishū (肺俞BL 13), Géshū (膈俞BL 17) and Wèishū (胃俞BL 21), with the time of cup retention for 8–10?min. The treatment was conducted once a day, and 10 treatments were considered as one course of treatment. Clinical efficacy was observed after one course treatment.Results
Among the 30 patients, 22 cases were cured, accounting for 73.33% (22/30), effective relief was found in 5 cases, accounting for 16.67% (5/30), and 3 cases had no improvement, accounting for 10.00% (3/30). The total effective rate was 90.00% (27/30).Conclusion
The clinical efficacy of acupuncture combined with cupping therapy for intractable hiccup is satisfactory, which is worthy of clinical promotion and application. 相似文献7.
Objective
To observe the effect of acupuncture at K?ngzuì (孔最LU 6) for hemorrhoids.Methods
Seventy six cases of hemorrhoids patients, 19 cases were diagnosed with internal hemorrhoids, 25 cases were diagnosed with external hemorrhoids, 32 cases were diagnosed with mixed hemorrhoids, they were treated with acupuncture, Kongzui (孔最LU 6) was perpendicular inserted bilaterally with a depth of 0.5-1cun, and reducing manipulation was performed. Treatment of 24 days were given and the improvement of hemorrhage and pain, the reducement of size of hemorrhoids and the recurrence were compared before and after treatment to evaluate the clinical efficacy.Results
Sixty eight cases were cured, which accounted for 86.5%, six cases were effective, which accounted for 7.9%, two cases were ineffective, which accounted for 2.6%.Conclusion
Acupuncture at K?ngzuì (孔最LU 6) bilaterally has sound effect for treatment of internal hemorrhoids, external hemorrhoids and mixed hemorrhoid. 相似文献8.
Objective
To summarize the timing-efficacy relationship and the dosage–efficacy relationship of acupuncture in stroke treatment.Method
Literature research was conducted for quantitative clinical studies of acupuncture in stroke treatment, with the entry point on the timing factor and dosage factor. A hierarchical analysis was performed on observing the time–efficacy relationship and the dosage–efficacy relationship before, during and after acupuncture.Results
Though the retrieved studies differ especially in such timing factors as needle retaining time, acupuncture interval and course, they share an agreement in the acupuncture intervention time point, acupuncture timing, specificity of acupoints and acupuncture manipulation.Conclusion
The optimal stimulation is the core of the research on the timing-efficacy relationship and the dosage–efficacy relationship of acupuncture and also the key to the clinical efficacy. 相似文献9.
Objective
To observe the clinical therapeutic effects on entrapment syndrome of superficial radial nerve treated with the short thrust needling at Shànglián (上廉LI 9).Methods
A total of 52 patients of entrapment syndrome of superficial radial nerve were treated with the short thrust needling at LI 9. Firstly, the needle was inserted gradually and deeply until the needle tip touched the radial periosterum. Secondly, the needle body was tilted to form an angle about 30° with the skin surface. Thirdly, the needle handle was lifted and trusted shortly and swiftly to induce the gentle rubbing of the needle tip on the periosterum. The stimulation intensity of this needling technique was determined by the obvious soreness and distention in the local area or the needling sensation radiated to the radial sides of the thumb, the index figure and the middle figure of the affected limb. Afterward, the needle was retained for 20?min. The treatment was given once a day, five treatments made one course and a total of 2 courses of treatment were required.Results
Of 52 cases, 50 cases were cured, accounting for 96.2% and 2 cases remarkably effective, accounting for 3.8%. The mean conduction velocity of the superficial radial nerve was (49.38?±?2.97) m/s after treatment, faster than (29.31?±?5.94) m/s before treatment, indicating the significant difference (P?<?0.05).Conclusion
The short thrust needling at LI 9 achieves the satisfactory clinical therapeutic effects on entrapment syndrome of superficial radial nerve. This therapeutic method is feasible to be promoted in clinical practice because of its less point selection and short treatment course. 相似文献10.
Objective
To report the clinical effects of acupuncture on alacrimia after child traumatic brain injury.Methods
One child with the alacrimia on the right eye after traumatic injury, aged 2 years and 3 months, was treated with acupuncture. The acupoint selection: Yángbái (阳白 GB 14), Cuánzhú(攒竹 BL 2), Tóngz?liáo (瞳子髎 GB 1), Sìbái (四白 ST 2), Yíngxiāng (迎香 LI 20), Yìfēng (翳风 TE 17) and Fēngchí(风池 GB 20) on the right side, as well as bilateral Hég? (合谷 LI 4) and Tàichōng (太冲 LR 3). The quick needling technique was applied to GB 20, LI 4 and LR 3 and the needles were retained for 20?min in the rest acupoints. In the embedding needle therapy, one group of acupoints was selected in each treatment, [Group No.1: BL 2, Sīzhúkōng (丝竹空 TE 23), ST 2 and Shàngyíngxiāng (上迎香 EX-HN 8); Group No. 2: Tàiyáng (太阳 EX-HN 5), TE 17, LI 20 and GB 14]. The embedding needle therapy was provided after the routine acupuncture treatment and the thumb-tack needles were embedded subcutaneously for 48 hours. The treatment with acupuncture was given once every other day, three times a week.Results
After 5 treatments, a full of tears was visible on the right eye when crying. After 10 treatments, there was a large amount of tears on the eyes and nasal discharge when crying. After 15 treatments, the lacrimal secretion and nasal secretion were normal when crying, without differences from the condition before traumatic brain injury.Conclusion
Acupuncture achieves the significant therapeutic effects on alacrimia after the child traumatic brain injury. 相似文献11.
Shanbin SUN Yanju LI Chong CHEN Panfu HAO Xiaoli SUN Yujie YANG Haowen TIAN Ermei CAO Sifang CHEN Wen ZHANG 《世界针灸杂志》2018,28(2):71-74
Objective
To observe the difference in clinical efficacy between governor vessel-unblocking and mind-regulating acupuncture therapy combined with conventional rehabilitation therapy and simply conventional rehabilitation therapy for sensory and motor dysfunction of patients with spinal cord injury.Methods
Forty patients with spinal cord injury (SCI) were randomly assigned into rehabilitation combined with acupuncture group (group A) and rehabilitation group (group B), with 20 patients in each group. In group A, governor vessel-unblocking and mind-regulating acupuncture therapy combined with conventional rehabilitation therapy was adopted, and B?ihuì (百会 GV 20), Fēngf? (风府 GV 16), Dàzhuī (大椎 GV 14), Zhìyáng (至阳 GV 9), Mìngmén (命门 GV 4) and Yāoyángguān (腰阳关 GV 3) were adopted as the main acupoints. Conventional rehabilitation therapy was also applied, including the rehabilitation training of joint, motion, respiration, urinary bladder and intestinal tract. In group B, conventional rehabilitation therapy was adopted as same as the group A. Treatment in the two groups was conducted for once a day, 6 times a week, and 12 weeks in total. ASIA motor score (MS), ASIA sensory score (SS) and activity of daily living (ADL) score of patients in the two groups were observed before and after the treatment.Results
Before treatment, the differences in MS, SS and ADL score of patients in the two groups were not statistically significant (all P > 0.05), and the results were comparable. After treatment, MS, SS and ADL score of patients in the two groups were all higher than that before the treatment (all P < 0.05), and MS, SS and ADL score of the patients in group A were all higher than that in group B (all P < 0.05).Conclusion
The curative effect of governor vessel-unblocking and mind-regulating acupuncture therapy combined with conventional rehabilitation therapy was superior to that of simply conventional rehabilitation therapy in the treatment of sensory and motor dysfunction of the patients with SCI. 相似文献12.
Objective
To compare the clinical efficacy difference between comprehensive ying needling therapy and intramuscular injection with ribavirin for mumps.Methods
One hundred patients with mumps were randomly divided into comprehensive ying needling therapy group (group A, 52 cases) and western medicine group (group B, 48 cases), then 8 cases were eliminated and drop out from group A and 4 cases were eliminated and drop out from group B respectively, actual inclusion 44 cases in group A 44 cases in group B. Point bloodletting was performed at parotid gland (腮腺Sāixiàn) and Threeshang acupoints of the patients in group A for once every other day, treatment for 7 days was considered as 1 course of treatment, and 2 courses were needed. Intramuscular injection with ribavirin was given to the patients in group B for twice a day, treatment for 7 days was considered as 1 course, and 2 courses were needed. The parotid gland swelling score, fever score, orifice parotid duct swelling score, score of difficulty in opening mouth and the clinical efficacy of the patients in the two groups were compared before and after treatment.Results
The cured and markedly effective rate in group A was 90.9% (40/44), which was superior to 68.2% in group B (30/44) (P?<?0.05). The symptom scores were all improved significantly in the two groups after treatment (all P?<?0.05), and the improvement in group A was superior to that in group B (all P?<?0.05).Conclusion
The curative effect of comprehensive ying needling therapy for treatment of mumps was superior to that of conventional western medicine therapy. 相似文献13.
Objective
To observe the clinical efficacy of knee joint pain treated with scraping combined with collateral bloodletting therapy in comparison with the routine acupuncture techniques.Methods
From March 2017 through to September 2017, 60 outpatients of knee joint pain were collected from the Acupuncture-Moxibustion Department. They were randomly divided into the group A (treated with scraping combined with collateral bloodletting therapy) and the group B (treated with the simple needling therapy of acupuncture), 30 cases in each one. Once treatment was given every day and 10 times consist of one course, two courses of treatment were required. At the end of treatment, the visual analogue scale (VAS) was adopted to evaluate the pain index, tenderness index and the overall effect of the patients in the two groups. Based on the Lysholm knee scale, the scores were compared in the patients of the two groups before and after treatment.Results
The total effective rate was 96.7% in the group A and was 86.7% in the group B, indicating the significant difference (P < 0.05). VAS value was 3.03 ± 0.62 in the group A and was 3.67 ± 0.74 in the group B after treatment, indicating that difference is statistically significant (P < 0.05). The Lysholm knee score was 89.2 ± 4.8in the group A and was 82.4 ± 2.6 in the group B after treatment, indicating that difference is statistically significant (P < 0.05).Conclusion
The scraping combined with collateral bloodletting therapy is significant in the efficacy on knee joint pain and feasible in the clinical guidance. 相似文献14.
Objective
To observe the clinical efficacy of surrounding electroacupuncture needling for breast mass after acute mastitis.Methods
Thirty patients with breast mass after acute mastitis who conformed to the inclusion criteria were given surrounding electroacupuncture needling. Acupoint selection: 4–8 needles were needled around the mass and at Zúsānl? (足三里ST 36), Sānyīnjiāo (三阴交SP 6), Fēnglóng (丰隆 ST 40) and R?gēn (乳根 ST 18). Electroacupuncture was performed at ST 36, SP 6 and ST 40. The above treatment was once a day. Treatment for 7 times was considered as 1 course of treatment, and 3 weeks were free from treatment between courses. Color ultrasound in breast was used to examine the breast mass before the next course of treatment, treatment can be terminated if the mass disappeared, otherwise, treatment should be continued. Three courses at most were needed.Results
After 1–3 courses of treatment, 16 patients were cured, accounting for 53.3% (16/30); markedly effective: 8 cases, accounting for 26.7% (8/30); effective: 4 cases, accounting for 13.3% (4/30); ineffective: 2 cases, accounting for 6.7% (2/30).Conclusion
Surrounding electroacupuncture needling for breast mass after acute mastitis was effective clinically. 相似文献15.
Objective
To explore the brain function mechanism of "liver-soothing and mind-regulating" acupuncture manipulation in intervening post-traumatic stress disorder (PTSD).Methods
According to random number table method, 60 SD rats were randomly divided into blank group, model group, grabbing group, paroxetine group and acupuncture group. Except for the blank group, all the rats were established into PTSD models through electric shock and incarceration, with model replication for 7 days in total. The rats were given gavage, acupuncture intervention and grabbing fixation 1?h before modeling, with 6 days as 1 course of treatment. Grabbing treatment was performed for 2 courses, with 12 days in total. After modeling, functional near-infrared spectroscopy (fNIRS) system was adopted to collect and record the changes of concentration of Oxy-Hb, Deoxy-Hb and Total-Hb during 3?min in related brain regions of rats in each group after treatment for 5 consecutive days, and the brain function was evaluated.Results
According to the comparison of the time series of blood-oxygen concentration, there were significant differences between model group and blank group as well as grabbing group and blank group (P < 0.01, P < 0.01), no significant difference was found between model group and grabbing group (P > 0.05); there were significant differences between paroxetine group and grabbing group as well as acupuncture group and grabbing group (P < 0.05, P < 0.05), no significant difference was found between paroxetine group and acupuncture group (P > 0.05).Conclusion
"Liver-soothing and mind-regulating" acupuncture manipulation has a benign regulatory effect on the blood-oxygen concentration in cerebral cortex of PTSD rats, which may be the important brain function mechanism of "liver-soothing and mind-regulating" acupuncture manipulation in intervening PTSD. 相似文献16.
Objective
To observe the clinical effects of the unilateral nervous tinnitus treated by He–Ne laser acupuncture.Methods
A total of 30 patients of unilateral nervous tinnitus were treated with He–Ne laser acupuncture. The disposable filiform needles of 0.40?mm?×?25?mm were used. ?rmén (耳门 TE 21), Tīnggōng (听宫 SI 19), Tīnghuì (听会 GB 2), Yìfēng (翳风 TE 17), Shuàig? (率谷 GB 8) and Zhōngzh? (中渚 TE 3) were adopted on the affected side. The input and output ends of the fiber-optic catheter of the laser instrument were connected at a pair of acupoints (TE 21 connect to SI 19, GB 2 connect to TE 17, GB 8 connect to TE 3). Each pair of acupoints was stimulated with He–Ne laser irradiation for 10?min, 8–10 mW in the output power and 6328?Å in the wavelength. The needles were retained for 30?min totally. The treatment was given once a day, 5 times a week, continuously for 2 weeks.Results
Of 30 cases, 19 cases were cured clinically, accounting for 63.3% (19/30); 7 cases effective remarkably, accounting for 23.3% (7/30) and 4 cases failed, accounting for 13.3% (4/30).Conclusion
He–Ne laser acupuncture achieves the satisfactory effects on treating nervous tinnitus and it is easily accepted by the patients. Hence, this therapy deserves to be promoted in clinical application. 相似文献17.
Wei-jian SONG Dan YANG Tian-gui JIA Zi-ju FENG Liang-ming YUE Xiong ZHANG Gang HE Yan-fang YANG Li CAO Bing LI Ding-wei JIAN Dong-mei GAO 《世界针灸杂志》2017,27(1):17-22
Objective
To observe the clinical efficacy of Taiji needling in treatment of peripheral facial neuritis.Methods
Sixty inpatients with peripheral facial neuritis were randomly divided into two groups: observation group (Taiji needling group, n=30) and control group (conventional acupuncture group, n=30); the treatment was conducted once a day, which was not stopped until the patients were discharged from hospital after recovery. The curative effect was evaluated before and after treatment by applying the therapeutic outcome rating scale of peripheral facial neuritis (portmann scale).Results
The improve ment of efficacy indices in the observation group was superior to that in the control group, and the difference was statistically significant (P<0.05); the course of treatment was shortened in the observation group compared with the control group, and the difference was also statistically significant (P<0.05).Conclusion
The efficacy index of Taiji needling in treatment of peripheral facial neuritis is superior to that of conventional acupuncture, and Taiji needling can obviously shorten the course of treatment. 相似文献18.
Objective
To observe the clinical efficacy of acupuncture–moxibustion therapy of "banking up original qi and consolidating the foundation" for prevention and treatment of seasonal allergic rhinitis.Methods
Sixty included patients were divided into two groups according to the random number table method with 30 patients in each group. In acupuncture group, warming-needle moxibustion was carried out at Zúsānl? (足三里ST 36), and cone moxibustion on Fùz? (附子Radix Aconiti Lateralis Praeparata) cake was conducted at Guānyuán (关元CV 4), Qìh?i (气海CV 6) and Dàzhuī (大椎GV 14). The treatment was conducted in May or June (2 months before the onset of rhinitis in this area). The treatment was carried out for once every other day and three times per week. Treatment for 24 times was considered as 1 course of treatment. No intervention treatment was conducted in control group. The score of rhinitis symptom, the visual analogue scale (VAS) score changes of total nasal symptom score (TNSS) and total non-nasal symptom score (TNNSS) of patients in 2015 and in 2016 were observed, and the clinical efficacy of the two groups was compared.Results
(1) The score of rhinitis symptom, the VAS score changes of TNSS and TNNSS in acupuncture group in 2016 declined when compared with the results in 2015, which were 4.57?±?0.82?vs 9.40?±?1.89, 13.37?±?4.01?vs 30.80?±?4.77 and 15.93?±?6.30?vs 46.13?±?9.79 (P?<?0.001), the results in acupuncture group after treatment were lower than that in control group at same time, which were 4.57?±?0.82?vs 7.53?±?2.06, 13.37?±?4.01?vs 27.17?±?6.84,15.93?±?6.30?vs 35.53?±?11.69(all P?<?0.001). According to comparison, there was no obvious difference in the results in control group at the two time points, which were 8.60?±?2.39?vs 7.53?±?2.06, 29.63?±?6.30?vs 27.17?±?6.84 and 40.90?±?12.31?vs 35.53?±?11.69 (all P?>?0.05). (2) The total effective rate was 96.7% (29/30) in acupuncture group and 10% (3/30) in control group, and the difference was statistically significant (P?<?0.001).Conclusion
Acupuncture–moxibustion therapy of "banking up original qi and consolidating the foundation" was effective on prevention and treatment of seasonal allergic rhinitis. 相似文献19.
Objective
To observe the effect of acupuncture at Jǐngjiājǐ (颈夹脊) on the repair and regeneration of cochlear hair cells of guinea pigs with sensorineural deafness.Methods
Sixty healthy guinea pigs were selected, 20 guinea pigs were randomly assigned to the normal control group (group A), and other guinea pigs were randomly divided into model control group (group B) and acupuncture treatment group (group C) after injection with gentamicin sulfate in order to induce deafness. No intervention was given to the guinea pigs in group A and group B, and acupuncture at Jǐngjiājǐ was given to the guinea pigs in group C for 30 days. ABR threshold, DPOAE amplitudes and hair cells counting of guinea pigs in each group were recorded after intervention for 30 days.Results
After intervention for 30 days, ABR threshold in group C was significantly lower than that in group B (38.46?±?7.36?vs 82.94?±?6.47, P<0.01), and the DPOAE amplitudes in group C were obviously higher than that in group B (28.06?±?5.64?vs 25.23?±?5.38, P<0.01). The number of cochlear hair cells in group C increased significantly, over 50% of the hair cells survived, accounting for 66.67% of the observation cases. The number of cochlear hair cells in the 3rd and 4th gyri was close to the normal level, and plenty of proliferous sustentacular cells can be seen. Compared with group B, the number of cochlear outer hair cells in each gyrus in group C significantly increased (36.76?±?1.97?vs 28.59?±?2.24, P<0.01), indicating that acupuncture at Jǐngjiājǐ can promote the repair and regeneration of cochlear hair cells.Conclusion
Acupuncture at Jǐngjiājǐ can promote the repair and regeneration of cochlear hair cells, thus improving the hearing of guinea pigs with deafness. 相似文献20.
目的 制备共同时递送紫杉醇-油酸前药(PTX-OA)和鸦胆子油(BJO)的分子配型纳米乳制剂(CMNEs)。方法 对基于分子配型组装技术的紫杉醇-油酸/鸦胆子油纳米乳制剂体外对HepG2细胞的抑制、细胞周期、细胞凋亡和体内抑制裸鼠肿瘤生长的评价。结果 紫杉醇-油酸/鸦胆子油纳米乳（PTX-OA/BJO CMNEs）粒径为108.7 2.3 nm,包封率> 95%。PTX-OA/BJO CMNEs对HepG-2细胞的毒性作用有浓度和时间依赖性,细胞周期试验表明PTX-OA/BJO CMNEs增加了G2/M期阻滞。注射PTX-OA/BJO CMNEs后的裸鼠模型中,对比注射生理盐水组,裸鼠肿瘤体积明显减少 (P<0.05),表明PTX-OA/BJO CMNEs在体内有很好抗肿瘤效果。进一步研究发现,PTX-OA/BJO CMNEs的抗肿瘤作用增强与诱导肿瘤细胞凋亡的能力有关,尤其是PTX-OA/BJO CMNEs可明显抑制肿瘤细胞的增殖和TOPO II的活性。结论 不同机制的两种药物联合给药能同时阻断不同的抗癌途径,从而提高治疗反应,降低毒性。 相似文献