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1.
Do Short and Sustained Periods of American College of Rheumatology/European League Against Rheumatism Remission Predict Functional and Radiographic Outcome in Early Rheumatoid Arthritis Patients With Low Overall Damage Progression?
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Nicole P. C. Konijn Lilian H. D. van Tuyl Maarten Boers Debby den Uyl Marieke M. ter Wee Pit Kerstens Alexandre E. Voskuyl Dirkjan van Schaardenburg Michael T. Nurmohamed Willem F. Lems 《Arthritis care & research》2017,69(7):989-996
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Daniel Aletaha Tuhina Neogi Alan J. Silman Julia Funovits David T. Felson Clifton O. Bingham Neal S. Birnbaum Gerd R. Burmester Vivian P. Bykerk Marc D. Cohen Bernard Combe Karen H. Costenbader Maxime Dougados Paul Emery Gianfranco Ferraccioli Johanna M. W. Hazes Kathryn Hobbs Tom W. J. Huizinga Arthur Kavanaugh Jonathan Kay Tore K. Kvien Timothy Laing Philip Mease Henri A. Mnard Larry W. Moreland Raymond L. Naden Theodore Pincus Josef S. Smolen Ewa Stanislawska‐Biernat Deborah Symmons Paul P. Tak Katherine S. Upchurch Jií Vencovský Frederick Wolfe Gillian Hawker 《Arthritis \u0026amp; Rheumatology》2010,62(9):2569-2581
Objective
The 1987 American College of Rheumatology (ACR; formerly, the American Rheumatism Association) classification criteria for rheumatoid arthritis (RA) have been criticized for their lack of sensitivity in early disease. This work was undertaken to develop new classification criteria for RA.Methods
A joint working group from the ACR and the European League Against Rheumatism developed, in 3 phases, a new approach to classifying RA. The work focused on identifying, among patients newly presenting with undifferentiated inflammatory synovitis, factors that best discriminated between those who were and those who were not at high risk for persistent and/or erosive disease—this being the appropriate current paradigm underlying the disease construct “rheumatoid arthritis.”Results
In the new criteria set, classification as “definite RA” is based on the confirmed presence of synovitis in at least 1 joint, absence of an alternative diagnosis that better explains the synovitis, and achievement of a total score of 6 or greater (of a possible 10) from the individual scores in 4 domains: number and site of involved joints (score range 0–5), serologic abnormality (score range 0–3), elevated acute‐phase response (score range 0–1), and symptom duration (2 levels; range 0–1).Conclusion
This new classification system redefines the current paradigm of RA by focusing on features at earlier stages of disease that are associated with persistent and/or erosive disease, rather than defining the disease by its late‐stage features. This will refocus attention on the important need for earlier diagnosis and institution of effective disease‐suppressing therapy to prevent or minimize the occurrence of the undesirable sequelae that currently comprise the paradigm underlying the disease construct “rheumatoid arthritis.”3.
Shahouri SH Michaud K Mikuls TR Caplan L Shaver TS Anderson JD Weidensaul DN Busch RE Wang S Wolfe F 《Arthritis and rheumatism》2011,63(11):3204-3215
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Tim L. Th. A. Jansen Nicola Dalbeth Jaap Fransen H. Ralph Schumacher Dianne Berendsen Melanie Brown Hyon Choi N. Lawrence Edwards Hein J. E. M. Janssens Frédéric Lioté Raymond P. Naden George Nuki Alexis Ogdie Fernando Perez‐Ruiz Kenneth Saag Jasvinder A. Singh John S. Sundy Anne‐Kathrin Tausche Janitzia Vaquez‐Mellado Steven A. Yarows William J. Taylor 《Arthritis \u0026amp; Rheumatology》2015,67(10):2557-2568
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Daiki Nakagomi Kei Ikeda Ayako Okubo Taro Iwamoto Yoshie Sanayama Kentaro Takahashi Mieko Yamagata Hiroaki Takatori Kotaro Suzuki Katsuhiko Takabayashi Hiroshi Nakajima 《Arthritis \u0026amp; Rheumatology》2013,65(4):890-898
Objective
The 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for rheumatoid arthritis (RA) refer to a possible use of ultrasound “for confirmation of the clinical findings.” We undertook this study to determine the optimized definition of ultrasound‐detected synovitis for the 2010 ACR/EULAR criteria and to assess the impact of its use on the accuracy of RA classification.Methods
One hundred nine patients with musculoskeletal symptoms for ≤3 years were enrolled in the study. Patients underwent clinical, laboratory, radiographic, and comprehensive ultrasonographic assessments at baseline and received routine management from expert rheumatologists who were blinded to the ultrasound findings.Results
Sensitivity and specificity of the 2010 ACR/EULAR criteria using different definitions of synovitis to identify patients who developed a disease requiring methotrexate (MTX) treatment within 1 year were 58.5% and 79.4%, respectively, for clinical synovitis (tenderness or swelling), 78.0% and 79.4%, respectively, for ultrasound‐detected synovitis with a gray‐scale (GS) imaging score ≥1 (GS ≥1 ultrasound synovitis), and 56.1% and 93.7%, respectively, for GS ≥2 ultrasound synovitis or a synovial power Doppler (PD) signal score ≥1 (GS ≥2/PD ≥1 ultrasound synovitis). Receiver operating characteristic curve analysis for the criteria scores revealed the largest area under the curve with GS ≥2/PD ≥1 ultrasound synovitis.Conclusion
Ultrasound assessment improves the accuracy of the 2010 ACR/EULAR criteria for identifying patients with a disease requiring MTX treatment. Our data provide preliminary but vital information for the methodology to confirm the presence of synovitis using ultrasound in the 2010 ACR/EULAR criteria.6.
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Dasgupta B Cimmino MA Maradit-Kremers H Schmidt WA Schirmer M Salvarani C Bachta A Dejaco C Duftner C Jensen HS Duhaut P Poór G Kaposi NP Mandl P Balint PV Schmidt Z Iagnocco A Nannini C Cantini F Macchioni P Pipitone N Amo MD Espígol-Frigolé G Cid MC Martínez-Taboada VM Nordborg E Direskeneli H Aydin SZ Ahmed K Hazleman B Silverman B Pease C Wakefield RJ Luqmani R Abril A Michet CJ Marcus R Gonter NJ Maz M Carter RE Crowson CS Matteson EL 《Annals of the rheumatic diseases》2012,71(4):484-492
The objective of this study was to develop EULAR/ACR classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new onset PMR and 169 non-PMR comparison subjects with conditions mimicking PMR. A scoring algorithm was developed based on morning stiffness >45 minutes (2 points), hip pain/limited range of motion (1 point), absence of RF and/or ACPA (2 points), and absence of peripheral joint pain (1 point). A score ≥4 had 68% sensitivity and 78% specificity for discriminating all comparison subjects from PMR. The specificity was higher (88%) for discriminating shoulder conditions from PMR and lower (65%) for discriminating RA from PMR. Adding ultrasound, a score ≥5 had increased sensitivity to 66% and specificity to 81%. According to these provisional classification criteria, patients ≥50 years old presenting with bilateral shoulder pain, not better explained by an alternative pathology, can be classified as having PMR in the presence of morning stiffness>45 minutes, elevated CRP and/or ESR and new hip pain. These criteria are not meant for diagnostic purposes. 相似文献
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Angelo Ravelli Francesca Minoia Sergio Davì AnnaCarin Horne Francesca Bovis Angela Pistorio Maurizio Aric Tadej Avcin Edward M. Behrens Fabrizio De Benedetti Lisa Filipovic Alexei A. Grom Jan‐Inge Henter Norman T. Ilowite Michael B. Jordan Raju Khubchandani Toshiyuki Kitoh Kai Lehmberg Daniel J. Lovell Paivi Miettunen Kim E. Nichols Seza Ozen Jana Pachlopnik Schmid Athimalaipet V. Ramanan Ricardo Russo Rayfel Schneider Gary Sterba Yosef Uziel Carol Wallace Carine Wouters Nico Wulffraat Erkan Demirkaya Hermine I. Brunner Alberto Martini Nicolino Ruperto Randy Q. Cron 《Arthritis \u0026amp; Rheumatology》2016,68(3):566-576
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Zulian F Woo P Athreya BH Laxer RM Medsger TA Lehman TJ Cerinic MM Martini G Ravelli A Russo R Cuttica R de Oliveira SK Denton CP Cozzi F Foeldvari I Ruperto N 《Arthritis and rheumatism》2007,57(2):203-212
OBJECTIVE: To develop criteria for the classification of systemic sclerosis (SSc) in children (juvenile SSc). METHODS: The study consisted of 3 phases: 1) collection of data on the signs and symptoms of actual patients with juvenile SSc that are useful for defining involvement of a particular organ; 2) selection of the parameters essential for the classification of juvenile SSc and preparation of a set of provisional classification criteria (PCC) using 2 Delphi surveys; 3) consensus conference consisting of 2 steps: discussion and rating of clinical profiles of 160 patients with definite juvenile SSc, possible juvenile SSc, or other fibrosing diseases as "having or not having juvenile SSc," using nominal group technique, and defining those PCC with the best statistical performance and highest face validity by using the clinical profiles of patients with definite juvenile SSc as the gold standard. RESULTS: In phase 1, 55 centers submitted clinical data on 153 patients with juvenile SSc. A total of 48 signs and symptoms were derived from these patient data and were used to define 9 organ system categories (cutaneous, vascular, gastrointestinal, respiratory, renal, cardiac, neurologic, musculoskeletal, and serologic). During phase 2, these were reduced to 21 criteria (3 major criteria [Raynaud's phenomenon, proximal skin sclerosis/induration of the skin, and sclerodactyly] and 18 minor criteria) and combined to generate 86 different PCC. At the consensus conference, these 86 definitions were tested on the case profiles of 127 patients with juvenile SSc. The PCC with the highest ranking were proximal sclerosis/induration and at least 2 minor criteria. CONCLUSION: These provisional classification criteria for juvenile SSc will help standardize the conduct of clinical research, epidemiologic and outcome studies, and therapeutic trials. 相似文献
11.
2013 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Systemic Sclerosis Outperform the 1980 Criteria: Data From the Canadian Scleroderma Research Group
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Hebah Alhajeri Marie Hudson Janet Pope Solène Tatibouet David Robinson Nader Khalidi Peter Docherty Ariel Masetto Jean‐Pierre Mathieu Sophie Ligier Tamara Grodzicky Sharon LeClercq Carter Thorne Geneviève Gyger Murray Baron 《Arthritis care & research》2015,67(4):582-587
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Felson DT Smolen JS Wells G Zhang B van Tuyl LH Funovits J Aletaha D Allaart CF Bathon J Bombardieri S Brooks P Brown A Matucci-Cerinic M Choi H Combe B de Wit M Dougados M Emery P Furst D Gomez-Reino J Hawker G Keystone E Khanna D Kirwan J Kvien TK Landewé R Listing J Michaud K Martin-Mola E Montie P Pincus T Richards P Siegel JN Simon LS Sokka T Strand V Tugwell P Tyndall A van der Heijde D Verstappen S White B Wolfe F Zink A Boers M 《Annals of the rheumatic diseases》2011,70(3):404-413
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Predicting Low Disease State and Remission in Early Rheumatoid Arthritis in the First Six Months,Comparing the Simplified Disease Activity Index and European League Against Rheumatism Response Measures: Results From an Early Arthritis Cohort
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Mohammed A. Omair Edward Keystone Vivian Bykerk Daming Lin Juan Xiong Ye Sun Gilles Boire J. Carter Thorne Diane Tin Janet Pope Carol Hitchon Boulos Haraoui Pooneh S. Akhavan 《Arthritis care & research》2017,69(5):737-741
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Value of the Routine Assessment of Patient Index Data 3 in Patients With Psoriatic Arthritis: Results From a Tight‐Control Clinical Trial and an Observational Cohort
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Laura C. Coates William Tillett Gavin Shaddick Theodore Pincus Arthur Kavanaugh Philip S. Helliwell 《Arthritis care & research》2018,70(8):1198-1205
Objective
To analyze the Routine Assessment of Patient Index Data 3 (RAPID3), a patient‐reported, composite index, designed initially for feasibility in clinical care. RAPID3 was developed in rheumatoid arthritis, but has been found useful in many rheumatic diseases. We analyzed RAPID3 in patients with psoriatic arthritis (PsA).Methods
Post hoc analyses were performed on 2 independent data sets, the Tight Control of Psoriatic Arthritis (TICOPA) clinical trial, and the Long‐Term Outcome in Psoriatic Arthritis Study (LOPAS II), an observational cohort. RAPID3 (range 0–30) is the total of three 0–10 scores for the Health Assessment Questionnaire disability index (recalculated from 0–3), pain visual analog scale (VAS), and global VAS. RAPID3 scores were compared to the Psoriatic Arthritis Disease Activity Score (PASDAS), the Disease Activity in Psoriatic Arthritis (DAPSA), and other available clinical measures, according to Spearman's correlation coefficients, standardized response mean, SEM, smallest detectible difference, minimally important difference (in patients who improved), and receiver operating characteristic curves. RAPID3 remission was compared to criteria for both standard minimal disease activity (MDA) and very low disease activity (VLDA).Results
RAPID3 was correlated significantly with PASDAS in TICOPA (r = 0.79, P < 0.01) and with DAPSA in LOPAS II (ρ = 0.59, P < 0.01), and with most other measures in both data sets. RAPID3 discriminated between tight control and standard care in TICOPA at 48 weeks at levels comparable to DAPSA and the PASDAS (P < 0.01). RAPID3 remission discriminated treatment groups in TICOPA intermediate between MDA and VLDA criteria.Conclusion
RAPID3 appears comparably informative to PASDAS and DAPSA in PsA, with greater feasibility for routine clinical care.18.
19.
The American College of Rheumatology Provisional Composite Response Index for Clinical Trials in Early Diffuse Cutaneous Systemic Sclerosis
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Veronica J. Berrocal Murray Baron Philip J. Clements Shervin Assassi Elena Schiopu Kristine Phillips Sindhu R. Johnson Janet E. Pope Jeffrey Siegel Weng Kee Wong Athol U. Wells Daniel E. Furst 《Arthritis care & research》2016,68(2):167-178
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