No-touch原则取大隐静脉在CABG中疗效分析与技术体会

目的 总结no-touch技术截取的大隐静脉在冠状动脉旁路移植术（CABG）中的近期效果与手术技术总结。方法 选取2017年1月至2018年10月在郑州市第七人民医院行CABG患者,常规技术取大隐静脉（SVG）行CABG共99例,为常规组;no-touch原则取大隐静脉行CABG共97例,为no-touch组。比较两组手术资料以及手术治疗效果和围术期并发生率差异性,比较1年后桥血管（左乳内动脉和大隐静脉）通畅率差异性。结果 ①两组患者手术时间、呼吸机辅助时间、重症监护室时间、引流量、下肢伤口愈合率疼痛评分、心肌损伤指标等比较差异无统计学意义;常规组新发心房颤动发生率（29.29%,29/99）显著高于no-touch组（19.59%,19/97）（P<0.05）。 ②两组乳内动脉通畅率比较差异无统计学意义;no-touch组SVG通畅率（93.57%,160/171）显著高于常规组（79.86%,111/139）（P<0.05）。结论 No-touch技术取的大隐静脉不增加手术风险与创伤,且no-touch技术截取的大隐静脉能够提高CABG术后中期通畅率。     

合并糖尿病的冠状动脉旁路移植术患者应用内镜采集大隐静脉的早期结果分析

目的对比研究内镜采集大隐静脉(EVH)和直视切开采集大隐静脉(OVH)在糖尿病患者接受冠状动脉旁路移植术(CABG中的应用及术后的早期结果。方法选取2013年8月至2015年1月我院外科手术治疗的176例单纯CABG患者,所有患者均合并有2型糖尿病,其中EVH组80例,OVH组96例。对比两组患者的围术期结果和住院期间切口相关并发症。术后1年时随访并行冠状动脉CT检查,评价静脉桥血管的通畅率。结果两组均无死亡病例。在血糖水平、获取静脉长度和静脉损伤方面两组没有显著性差异。与OVH组相比,EVH组在获取静脉时间(P=0.028)、切口长度(P0.001)、腿部切口并发症、术后疼痛及患者满意度方面(P0.001)有明显优势。与OVH组相比,EVH组术后早期下地活动时间缩短(P=0.033)。两组患者术后住院时间、住院死亡率和静脉桥血管通畅率的差异无统计学意义。结论 EVH可以满足糖尿病患者接受CABG对移植静脉血管的手术要求,微创快速,安全有效。EVH与OVH比较术后1年静脉桥血管通畅率无显著性差异。     

复合桥血管在冠状动脉病变合并升主动脉严重钙化小切口冠状动脉旁路移植术中的应用及对中期通畅率的影响

目的探讨Y型复合桥血管(左胸廓内动脉-桡动脉、左胸廓内动脉-大隐静脉)在左前外侧小切口冠状动脉旁路移植术(MIDCAB)中的应用以及术后中期通畅率。方法回顾性分析2013年1月至2015年5月38例冠状动脉病变合并升主动脉严重钙化患者应用Y型复合桥血管的MIDCAB临床资料。男29例、女9例,年龄56~83〔平均(67.8±8.2)〕岁,通过冠状动脉血管造影(CTA)评估术后1年桥血管通畅率。结果全例均顺利完成MIDCAB,无术中转正中开胸,平均手术时间为(3.6±1.1)h,24例采用左胸廓内动脉-桡动脉Y型复合桥血管,14例采用左胸廓内动脉-大隐静脉Y型复合桥血管,平均吻合移植血管(2.7±0.5)支。无围术期二次开胸止血、无术后脑卒中发生以及围术期心梗发生,围术期新发心房颤动3例,经对症治疗恢复窦性心律;肾衰竭1例,经血液透析治愈;ICU入住时间(52.8±19.2)h,全组无住院死亡。术后1年通过冠状动脉CTA随访显示,桥血管的总通畅率为97.1%,其中全部患者左胸廓内动脉-左前降支吻合口通畅率为100%,左胸廓内动脉-桡动脉组出现桡动脉桥血管线征1例,左胸廓内动脉-大隐静脉桥血管阻塞1例,累积桥血管通畅率:左胸廓内动脉-桡动脉桥血管与靶血管吻合通畅率为95.8%,左胸廓内动脉-大隐静脉与靶血管吻合通畅率为92.8%(P>0.05)。结论对于冠心病合并升主动脉严重钙化患者而言,MIDCAB术中采用Y型复合桥血管安全、有效,中期通畅率良好。全动脉桥血管(左胸廓内动脉-桡动脉)是最佳方案,但对于桡动脉无法使用或获取后可能发生手部缺血等并发症的患者,左胸廓内动脉-大隐静脉复合桥血管仍是一种良好的选择。     

冠状动脉旁路移植术后近中期桥血管闭塞的相关高危因素分析

目的 分析冠状动脉旁路移植术（coronary artery bypass graft,CABG）后近中期桥血管的通畅率及其相关的危险因素,为术后患者预防桥血管病变提供依据。方法 选取2009年9月至2014年9月在衡水市人民医院心外科接受首次CABG术患者38例,入选的患者在复查期间未再行任何血管再通术（PTCA、PCI及CABG等）,术后4～59（28.1±17.6）个月复查时均行CTA检查,部分患者行CAG检查对照,分别计算动脉桥血管和静脉桥血管的通畅情况,分析影响CABG术后患者桥血管通畅情况的高危因素。结果 CABG术后桥血管的总体通畅率为75.3%;LIMA的总体通畅率为92.9%,SV的总体通畅率为64.4%。结论 乳内动脉桥血管通畅率明显高于大隐静脉桥血管;患者的手术年龄、性别以及综合相关危险因素等都会影响桥血管通畅率。     

双源CT评价冠状动脉搭桥术后桥血管通畅率的临床研究

目的比较非体外循环下冠状动脉旁路移植术（OPCABG）与常规冠状动脉旁路移植术（常规CABG）术后5年血管桥的通畅率。方法2006年1月至2008年1月间40例单独行冠状动脉旁路移植术（CABG）的患者资料回顾性地被分为OPCABG组和常规CABG组。OPCABG组通过胸骨正中切口,在非体外循环心脏不停跳下完成CABG;常规CABG组建立常规体外循环心脏停搏下完成CABG。两组术前的一般情况无明显差异。利用双源CT造影检查及CT图像后处理,研究两种术式各条血管桥的通畅情况。结果常规CABG组及OPCABG组左乳内动脉（uMA）到前降支（LAD）的通畅率都达到100％,静脉桥的通畅率分别为93．87％和94．23％,组间比较差异均无统计学意义。结论OPCABG旁路血管桥的3~5年通畅率可以和常规CABG相媲美。OPCAB治疗冠心病的初期结果显示可以减少术后并发症,减少患者术后呼吸机辅助时间、ICU留观时间和住院时间,降低住院费用。     

内窥镜下取小腿大隐静脉用于冠状动脉搭桥的临床效果

目的:评价内窥镜下采集小腿大隐静脉,用于非体外循环冠状动脉搭桥术(off pump coronary artery bypass grafting,OPCABG)的临床效果。方法:选取OPCABG患者269例,根据小腿大隐静脉取材方式将患者分为,内窥镜血管采集(endoscopic vein harvesting,EVH)组和全程切开(open vein harvesting,OVH)组,比较两组取材时间、取材质量、切口并发症、围术期和术后近期随访时的临床效果及患者评价。结果:EVH组取材长度、血管质量和取材时间可满足冠状动脉搭桥手术需要。与OVH组相比,EVH组术后切口并发症发生率和下肢水肿发生率显著降低,且差异有统计学意义,但皮下组织瘀斑发生率较OVH组高。取材时间EVH组平均35 min,OVH组平均45 min,差异有统计学意义。远端吻合口数目EVH组3.2个/例,OVH组3.1个/例,差异无统计学意义。两组围术期心肌梗死发生率差异无统计学意义。本研究中,所有患者均痊愈出院,术后平均随访4～5个月,均无心绞痛再发。结论:CABG术中采取EVH取小腿大隐静脉的方法有效可行。其作为一种微创取血管的方法,取材质量良好、切口小、并发症更少,得到了医生和患者的认可。     

桡动脉-大隐静脉组合V形桥在冠状动脉旁路移植术中的应用

目的:对桡动脉-大隐静脉组合V形桥新术式的安全性和近期移植血管通畅率进行初步探讨。方法:选自2015年4月至2016年3月,我院共完成29例桡动脉-大隐静脉组合V形桥冠状动脉旁路移植(CABG)术。平均年龄(65. 3±8. 2)岁,女性4例(16%)。将大隐静脉与升主动脉做近端吻合,桡动脉与该大隐静脉端侧吻合,吻合口距升主动脉的距离≤0. 5 cm。对术后30 d死亡率,桡动脉-大隐静脉组合V形桥吻合口以及远端吻合口的近期通畅性(术后6个月)进行影像学评价。结果:术后30 d死亡率为零;术后6个月对桡动脉-大隐静脉组合V形桥吻合口及远端吻合口的通畅性应用冠状动脉CTA进行评价,通畅率均为100%。结论:桡动脉-大隐静脉组合V形桥CABG术是一种安全有效的新术式,临床效果满意,近期通畅率高。     

内窥镜获取大隐静脉在冠状动脉旁路移植术中的临床研究

目的分析比较内窥镜与传统开放式获取大隐静脉应用于冠状动脉旁路移植术(CABG)的早期临床效果。方法纳入2010年3月至2013年1月298例采用内窥镜静脉采集法(EVH)行CABG的患者(EVH组),并与同期309例采用传统切开静脉采集法(CVH)行CABG的患者(CVH组)进行比较,对比两组患者术前资料、手术情况和术后并发症。结果两组患者在获取静脉时间、获取静脉长度、静脉桥数、总手术时间、术后住院时间以及切口感染或延迟愈合、切口血肿、局部皮肤坏死、皮炎发生率等方面比较,差异均无统计学意义(均P0.05);而EVH组患者住院期间腿部疼痛(17.4%比51.1%,P=0.000)、住院期间腿部水肿(0.7%比32.7%,P=0.000)及淋巴漏(0比7.4%,P=0.000)发生率均显著低于CVH组,差异有统计学意义。结论 CABG术中应用EVH能够显著减轻创伤,降低术后并发症的发生率。     

加压试验在采集大隐静脉桥血管中的应用

目的观察加压试验在采集大隐静脉桥血管中的应用及安全性。方法选择我院2012年10月—2015年9月行冠状动脉旁路移植术(CABG)中应用加压试验采集大隐静脉桥血管病例126例,男81例,女45例;年龄33岁~81岁。术中使用桥血管采集左乳内动脉及大隐静脉,采集大隐静脉时应用加压试验间断小切口。术中观察桥血管大体质量及术后效果进行相关性分析。结果全组126例病人良好,术中应用加压试验顺利,桥血管无破损,术后无因静脉桥血管质量而发生大出血病例,其中1例皮下瘀血,经引流后好转,无切口感染病例,术后随访无近期心血管事件发生。结论 CABG已成熟,且大隐静脉桥血管采集方法较多,但大隐静脉桥血管的质量及远期效果有待进一步研究。     

非体外循环冠状动脉旁路移植术中不同方式获取大隐静脉的近中期临床效果

目的分析非体外循环冠状动脉旁路移植术(OPCABG)不同方式获取大隐静脉的近期和中期临床效果。方法选择在我科接受择期OPCABG的患者435例,根据获取大隐静脉的方式,分为内窥镜获取大隐静脉(edoscopic vein harvesting,EVH)组217例及开放式获取大隐静脉(open vein harvesting,OVH)组218例,比较2组围术期病死率、急性心肌梗死、低心排综合征和腿部切口并发症等不良事件发生率,随访6个月和1年,比较2组静脉桥血管狭窄或闭塞比例和腿部切口并发症。结果 EVH组围术期腿部切口并发症发生率明显低于OVH组(2.30%vs 12.84%,P=0.000)。EVH组与OVH组围术期病死率(1.38%vs 2.29%,P=0.724)、急性心肌梗死(1.38%vs1.83%,P=1.000)和低心排综合征发生率(1.84%vs 2.75%,P=0.751)比较,差异均无统计学意义。术后6个月随访,EVH组与OVH组发生桥血管狭窄或闭塞比例比较,差异无统计学意义(8.76%vs 9.17%,P=1.000),EVH组腿部切口相关并发症发生率明显低于OVH组(3.69%vs 17.89%,P=0.000)。术后1年随访,EVH组与OVH组发生桥血管狭窄或闭塞比例比较,差异无统计学意义(11.52%vs 14.22%,P=0.475),EVH组腿部切口相关并发症发生率明显低于OVH组(5.53%vs 25.69%,P=0.000)。结论 EVH与OVH围术期不良事件发生率相似,但EVH术后腿部切口相关并发症发生率低于OVH,较OVH有明显优势。     

内窥镜采集大隐静脉在冠状动脉旁路移植术后近、中期的疗效分析

目的比较冠状动脉旁路移植术（CABG）中应用内窥镜采集与直视切开采集大隐静脉的近、中期临床效果。方法纳入2005年4月~2010年1月行CABG治疗且随访资料完整的冠心病患者268例。根据大隐静脉的采集术式分为两组,使用内窥镜采集大隐静脉的患者进入内镜组（EVH组,n=129）,采用直视切开采集大隐静脉的患者进入切开组（OVH组,n=139）,应用64排螺旋CT（64-MSCT）对比分析手术后3个月、1年、3年大隐静脉桥通畅率。结果 EVH组与OVH组术后3个月、1年、3年大隐静脉桥通畅率均无统计学差异[分别为（88.0%vs.85.6%）,（78.9% vs.79.9%）,（72.2% vs.71.8%）, P＜0.05],但EVH组采集时间更长[（50.23±5.87）min vs.（38.65±7.96）min],破损情况更多[（1.51±0.19） vs.（0.84±0.04）],差异有统计学意义（P＜0.05）。结论内窥镜和直视切开两种采集方式的大隐静脉桥近、中期通畅率接近,但内窥镜法采集时间较长,静脉破损较多。     

Does No-Touch Technique Better than Conventional or Intermediate Saphenous Vein Harvest Techniques for Coronary Artery Bypass Graft Surgery: a Systematic Review and Meta-analysis

Saphenous vein (SV) is a common graft being used in coronary artery bypass grafting (CABG). Conventional (CON), intermediate (I), and no-touch (NT) are the most common harvesting techniques of SV for CABG. The aim of this study is to systematically review the NT versus CON and I techniques in harvesting SV for CABG. Twelve databases were searched for randomized controlled trials comparing the CON, I, and NT techniques in harvesting SV for CABG. Twelve reports of six RCTs were included. Our meta-analysis showed that with NT technique, patency rate was significantly higher when compared to I technique up to 18-month follow-up duration. In contrast, this significant difference was not maintained in terms of minor complications of leg wounds with both techniques. The NT has significantly higher patency rate compared to I vein harvesting technique. However, more RCTs are warranted to confirm these results.     

Initial results and long-term outcome of percutaneous coronary intervention in patients with previous coronary artery bypass grafting

OBJECTIVES: The incidence of percutaneous coronary intervention following bypass surgery(coronary artery bypass grafting: CABG) is not low, but the outcomes of patients requiring percutaneous coronary intervention after CABG are not well known. METHODS: From June 1970 to June 2000, 2,981 patients underwent CABG at our institute using 6,747 grafts including 2,875 saphenous vein graft(SVG), 3,042 internal thoracic artery(ITA), 706 gastro-epiploic artery(GEA), 122 radial artery(RA), and 2 others. Three hundred twenty-seven patients underwent subsequent percutaneous coronary intervention in 520 lesions(104 SVG, 97 ITA, 12 GEA, 8 RA, 299 native artery). The initial results and long-term outcome following percutaneous coronary intervention in these 520 consecutive procedures were evaluated retrospectively. RESULTS: Percutaneous coronary intervention to arterial grafts were performed mainly within the early post-operative period, whereas percutaneous coronary intervention to vein grafts had two periodic peaks in the early post-operative period and at 7 years after CABG. Procedural success rate of percutaneous coronary intervention was 90% for SVG, 81% for ITA, 58% for GEA, 88% for RA, and 87% for native arteries. Restenosis rate was 56% for SVG, 30% for ITA, 83% for GEA, 83% for RA, and 49% for native arteries. Cardiac events after percutaneous coronary intervention with previous CABG were greater in cases of ITA, followed by native arteries, SVG, GEA and RA(p = 0.0046). In the early post-operative period, there was no significant difference between ITA and SVG. In the chronic stage, the prognosis of cardiac events after PCI for SVG was worse than for ITA. CONCLUSIONS: Percutaneous coronary intervention after CABG requires strategic consideration based on target-specific initial results and long-term outcome.     

Endoscopic saphenous vein harvesting for CABG -- a randomized,prospective trial

BACKGROUND: The saphenous vein is an established conduit for coronary revascularization. Disadvantages of traditional harvest technique are significant pain and morbidity. We compared the endoscopic harvest technique with the traditional method. METHOD: 140 coronary artery bypass graft (CABG) patients were randomized into 2 groups: endoscopic vein harvesting (EVH; n = 80) and traditional open vein harvesting (OVH; n = 60). Analysis included preoperative risk factors for wound complication, harvesting time, graft injury, and intraoperative and postoperative complications. Patient follow-up lasted 3 months. RESULTS: The preoperative risk profiles of the groups were comparable. In the EVH group, 5 patients (7.1 %) had to be switched to the open technique. EVH time was 45 +/- 6.2 min vs. 31.1 +/- 6.5 min. Two patients (2.5 %) had to be revised because of bleeding complication vs. 6 (10 %) in the OVH group. No local infections or wound complications were observed in the EVH group vs. 11 (18 %) cases in the OVH group. Two OVH cases (3.6 %) were readmitted for wound debridement. All EVH patients reported less pain and were completely satisfied by the cosmetic results. CONCLUSION: EVH is a safe and efficient technique for CABG. Morbidity was significantly lower, with reduced pain and better cosmetic results. EVH time was significantly longer compared to the traditional harvesting technique.     

Outcomes of left internal mammary artery with saphenous vein composite graft to bypass the left anterior descending artery: a propensity-matched study

BackgroundThis study aimed to evaluate the early and mid-term outcomes of a novel strategy of using the in-situ left internal mammary artery (LIMA) with the great saphenous vein graft (SVG) to bypass the left anterior descending artery (LAD) in coronary artery bypass grafting (CABG).MethodsA total of 979 patients took part in this retrospective observational study; 83 patients were propensity-score matched to the LIMA + SVG group and 83 to the LIMA − LAD group. Early mortality, postoperative complications, mid-term major adverse cardiovascular and cerebrovascular events (MACCE) were compared among the two matched groups after the procedure.ResultsNo significant differences in early mortality and postoperative complications rates were detected between the two matched groups. For mid-term outcomes, the incidence of MACCE was slightly higher in the LIMA + SVG group, but there was no significant statistical difference (14.9% vs. 12.8%, hazard ratio =1.20, 95% CI, 0.24 to 7.95; P=0.70) between the matched groups. Computed tomography coronary artery angiography (CTCA) images showed a LIMA + SVG composite graft patency rate of 94% (32/34) 25 months after the procedure.ConclusionsUsing the in situ LIMA with SVG to revascularize LAD was associated with comparable early and mid-term outcomes. These findings may provide an alternative emergency strategy when in situ LIMA cannot bypass LAD. Further study needs to be conducted to test longer-term outcomes.     

Individual Versus Sequential Saphenous Vein Grafts for on-Pump Coronary Artery Bypass Grafting – Does Smaller Coronaries in Indians Affect Graft Choice? – A Mid-Term Patency Comparison Study

PurposeAlthough multiarterial grafting or bilateral mammary artery use is being increasingly emphasized for contemporary coronary artery bypass grafting (CABG) practice, saphenous vein graft (SVG) still accounts for 80% of all CABG conduits (Park et al., 2020) [1]. In India, both the individual and sequential saphenous grafting techniques are used arbitrarily, and there has not been a study that compares the mid-term patency of these two. This is specially relevant in view of smaller coronaries in Indians than the Caucasian counterparts. This study aims to compare the patency for on pump CABG’s.MethodsIn the present study, 323 patients underwent either sequential (group A, N = 151 grafts, each graft having two anastomoses each) or individual (group B, N = 344 grafts) saphenous vein CABG, between February 2014 and June 2017. The SVG anastomoses were created on obtuse marginal (OM1/OM2) and posterior descending artery (PDA). The graft patency of the vein grafts as well as the left internal mammary artery were assessed by serial coronary angiograms.ResultsResults were evaluated at 6 months, 1, 2 and 3 years post operatively. Group A showed a higher graft patency at 3 years at 80.8%, and group B, 67.1% (P = 0.002). Also, anastomoses on sequential conduits had overall better patency rates at three years (77.2% vs 67.2%, P = 0.005). The groups showed similar results at one year post operatively.ConclusionsSequential bypass grafts were associated with superior mid-term patency compared with individual grafts. These findings suggest the more favourable results of sequential bypass grafting to be attributed to the enhanced flow haemodynamics.     

No-touch大隐静脉技术应用于冠脉旁路移植术中疗效的Meta分析

目的 通过Meta分析的方法评价No-touch大隐静脉技术与传统技术行冠状动脉旁路移植术(CABG)的疗效差异.方法 计算机检索中国生物医学文献数据库(CBM)、中国期刊全文数据库(CNKI)、万方数据库(WanFang Data)、维普(VIP)、PubMed、Cochrane Library临床试验注册数据库、E...     

Comparison of the rheologic parameters in left internal thoracic artery grafts with those in saphenous vein grafts.

BACKGROUND: Left internal thoracic artery (LITA) grafts have superior patency to saphenous vein grafts (SVG). Because shear stress augments the release of nitric oxide throughout the LITA endothelium, shear stress and shear rate in coronary artery bypass grafts (CABG) may play an important role in the higher patency, so the aim of the present study was to evaluate and compare the rheologic parameters in CABG using LITA and SVG. METHODS AND RESULTS: Rheologic examinations were done in 197 patients using a vacuum-suction glass tube viscometer after CABG surgery was completed. Shear stress and shear rate were calculated from the geometry of the graft, blood flow in the graft and blood viscosity. Of 197 patients, 177 underwent LITA grafting to the left anterior descending artery (LAD) and 160 had SVG anastomosis to coronary arteries. Mean wall shear stress in the LITA grafts to the LAD (13.8+/-1.0 dyne/cm2) was nearly 4-6-fold larger than that in the SVG grafts. Mean shear rate (559.1+/-57.0 s(-1)) of LITA-LAD grafts was approximately 2-3-fold higher than that of SVG. CONCLUSION: These results suggest that high wall shear stress and shear rate play an important role in the higher patency rate of LITA grafts.     

Serial angiographic follow-up beyond 10 years after coronary artery bypass grafting.

BACKGROUND: The long-term prognosis and serial angiographic follow-up beyond 10 years in patients who underwent coronary artery bypass grafting (CABG) have not been fully studied in Japan. METHODS AND RESULTS: In the present study data from 71 patients who underwent CABG before 1992 were analyzed. Thirty patients had a saphenous vein graft (SVG) only group, and the remaining 41 had a left internal thoracic artery graft to the left anterior descending coronary artery (LITA) group; 6 patients died from malignancy, which was the most common cause of death after CABG. The major adverse cardiac events (MACE) were defined as cardiac death, Q-wave or nonQ-wave myocardial infarction, and congestive heart failure. The MACE-free rate was significantly higher in the LITA group than in the SVG group (p < 0.05). However, among the patients with an ejection fraction < 0.40, there was no significant difference in MACE-free rate between the 2 groups. The LITA patency rate was significantly higher than that for SVG (p < 0.05) and the SVG patency rate was lower in the patients with hyperlipidemia (p < 0.05); cholesterol-lowering therapy improved the SVG patency rate. CONCLUSION: The long-term outcome of CABG was favorable, particularly if using an arterial graft. Although the patency rate was lower for the SVG than LITA, the patient's lipid profile might be an important factor in the SVG patency rate.     

大隐静脉和上臂头静脉移植对70岁以上病人心肌血管重建作用的比较

目的　冠状动脉旁路移植术是治疗缺血性心脏病一种常规方法 ,但是由于所采用的移植血管不同 ,导致治疗的效果也不尽相同。目前治疗常用的血管为大隐静脉 +乳内动脉为标准手术术式。然而诸多原因限制 ,有时大隐静脉不适合作为移植材料。本研究对大隐静脉与上臂头静脉作为移植材料进行比较。方法　接受乳内动脉和大隐静脉旁路移植术组 35例 ,平均年龄 77岁 ,接受乳内动脉 +上臂头静脉旁路移植术组 15例 ,平均年龄 75岁 ,二组之间 ,体重 ,心肌梗死病史 ,心功能 ,平均每例冠状动脉病变以及平均移植血管数没有明显差别。结果　乳内动脉和大隐静脉旁路移植术组和乳内动脉 +上臂头静脉旁路移植术组之间 ,乳内动脉的五年累计通畅率分别为 96 %和94 % ,二组之间没有显著性差异 (P>0 .0 5 ) ,大隐静脉的通畅率为 70 % ,上臂头静脉为 4 8% ,二组之间差异性不明显 (P>0 .0 5 )。结论　通过两组间的 5年累计通畅率的比较 ,我们认为在高龄病人上臂头静脉作为移植血管效果差 ,术后通畅率低 ,但可以作为移植血管的最后选择。