疣状皮肤结核1例

患者男,26岁。因左大腿环状斑块半年,于2005年1月就诊。患者7个月前发现左大腿屈侧无明显诱因出现一红色丘疹,伴疼痛。在当地医院予手术切除。2周后伤口愈合。1个月后在伤口周围出现红色斑块,逐渐向周围扩展,呈环状,无自觉症状。半年来皮损扩展至手掌大,中心部分皮损消退。既往     

臀部疣状皮肤结核1例

疣状皮肤结核是临床上较常见的一类皮肤结核。由于病程慢性,无明显的临床症状,易被忽视或误诊。本文报道1例病史长达10年余、经过抗结核治疗后病情得到明显改善的患者。临床资料患者男,20岁,工人。因右臀部暗红色斑片,伴结节、结痂、脱屑10年余,脓疱半月就诊。     

足部疣状皮肤结核1例

疣状皮肤结核（tuberculosis verrucosa cutis）是一种典型的外源性皮肤结核。笔者近期诊治1例非典型的足部疣状皮肤结核患者,现报告如下。     

足部疣状皮肤结核1例

临床资料患者,男,47岁。因左足部皮疹35年于2009年7月22日就诊于我科。患者于35年前无明显诱因于左足底出现一直径约2.0cm×2.0cm大小隆起性的皮疹,无不适及破溃,后皮疹渐扩大,表面有     

疣状皮肤结核1例

报告1例疣状皮肤结核。患者男,39岁。右下肢膝关节内下方出现结节、红斑疣状增生、萎缩8年余。无明显自觉症状。皮肤组织病理:表皮角化不全,上皮细胞增生,部分区基底细胞松解,中性粒细胞浸润,真皮层内见由上皮样细胞、郎格罕氏细胞、淋巴细胞、浆细胞组成的肉芽肿性结节,其周围见组织细胞浸润,含铁血黄素沉积。     

非典型疣状皮肤结核1例

皮肤结核是由结核杆菌直接侵犯皮肤,或其他脏器结核病灶内的结核杆菌经血行或淋巴系统传播到皮肤组织引起的皮肤损害。笔者诊治1例被误诊为着色芽生菌病的疣状皮肤结核患者,现报告如下。     

手部疣状皮肤结核1例

患者男,54岁。左手掌及腕部出现疣状结节及斑块10年余。皮损组织病理示表皮角化过度伴角化不全,假上皮瘤样增生,真皮浅层见结核样浸润,无明显干酪样坏死。结核菌素试验弱阳性,抗酸染色(-),皮损组织真菌培养(-)。诊断:疣状皮肤结核。     

臀部皮肤结核一例

患者,男,54岁。右侧臀部暗红色斑块6年,曾多次按“股癣、湿疹”等治疗效果不佳。真菌涂片呈阴性,PPD试验强阳性（+++）,皮损取活检组织病理为感染性肉芽肿性改变。结合临床及病理诊断为臀部皮肤结核,给予异烟肼、利福平、乙胺丁醇抗结核治疗后,皮损好转。     

误诊为疣状皮肤结核的着色真菌病1例

患者男 ,49岁 ,农民 ,患病前从事拖拉机手的工作。 10年前无明显诱因发现右前臂伸侧出现数个红色结节样损害 ,触之较硬 ,无痒痛等不适。此后皮损逐渐发展至腕部 ,渐增多 ,并相互融合 ,形成斑块 ,表面凹凸不平。 3年前开始皮损明显扩大 ,病情加重 ,皮损时常破溃 ,并有少量脓性分泌物。患者曾数次就诊于当地医院 ,未做明确诊断 ,曾间断外用肤轻松、红霉素、克霉唑等无效。 1年前在当地医院做皮肤活检 ,诊断为“疣状皮肤结核” ,口服异烟肼治疗 1年 ,仍无效 ,遂来诊。家庭中其他成员无此类似病史。体检 :就诊时一般情况好 ,体温正常 ,全身浅表…     

疣状皮肤结核误诊分析

疣状皮队结核发生率小，医师往往对此警惕性不够，极易误诊，现把遇到的1例分析如下。     

A Case of Extensive Multifocal Tuberculosis Verrucosa Cutis

Tuberculosis is probably as old as the human race itself. Cutaneous tuberculosis constitutes a very small proportion of extra pulmonary tuberculosis. Extensive, multifocal involvement of cutaneous tuberculosis is a very rare manifestation. We report one such case of extensive, multifocal tuberculosis verrucosa cutis in a 30-year-old immunocompetent male patient in the absence of any primary tubercular focus.     

A Case of Tuberculosis Cutis Orificialis with Perianal Involvement

Tuberculosis cutis orificialis (TCO) is a rare manifestation of cutaneous tuberculosis that is caused by auto-inoculation of mycobacteria in patients with advanced internal tuberculosis. TCO occurs in oral, perianal, or genital mucosa and adjacent skin. The tongue is the most frequently affected site, but the perianal area can also be affected. A 39-year-old male presented with a 4-month history of painful ulcers on the perianal area. The histopathologic findings revealed granulomatous infiltrates composed of epithelioid cells and Langhans-type giant cells in the dermis, and a few acid-fast bacilli noted on Ziehl-Neelsen staining. The polymerase chain reaction (PCR) was positive for Mycobacterium tuberculosis and the chest X-ray showed findings consistent with active pulmonary tuberculosis in both upper lung zones. The skin lesion showed complete resolution 2 months after the start of treatment with antituberculosis agents. We report a case of TCO with perianal involvement in a patient with underlying active pulmonary tuberculosis.     

误诊为皮肤结核的着色芽生菌病1例

患者男,52岁,病程20余年,主要为外伤后左下肢出现红斑、斑块,继发结节、疣状增生.以"皮肤结核"治疗,无效.后经组织病理及真菌培养确诊为着色芽生菌病,予系统抗真菌和热疗等.     

应用聚合酶链反应诊断疣状皮肤结核1例报告

报告１例４５岁女性疣状皮肤结核患者，病期１３年。于右臀部至右大腿后上方、右耳廓及右胸部呈现肉芽肿性皮损。组织病理疑为结核，抗酸染色（一）。遂将石蜡切块作聚合酶链反应（ＰＣＲ）检查，扩增出结核杆菌特异ＤＮＡ片段。经抗痨治疗皮损治愈。     

溃疡性皮肤结核误诊为Bowen病1例

患者男,53岁。肛周起丘疹、溃疡伴疼痛4年余。在外院诊断为"鲍温病",经放射治疗未愈。检查肛周见一10.5cm×7.0cm的溃疡面,表面高低不平,有暗红色、鲜红色、苍白色肉芽组织,边缘潜行。胸部X线示双上肺结核。结核菌素试验阳性。病理检查诊断为溃疡性皮肤结核。     

Tuberculosis Verrucosa Cutis Presenting as Diffuse Plantar Keratoderma: An Unusual Sight

Tuberculosis verrucosa cutis (TVC) is a common cutaneous form of paucibacillary tuberculosis in an individual with moderate to high degree of immunity to Mycobacterium tuberculosis infection. Clinical appearance of TVC is mostly very typical with well-defined warty plaques presenting mostly on hands, knees, ankle, and buttocks; however several atypical morphology of the lesions have also been described. We hereby report a case of TVC, masquerading as asymptomatic diffuse keratoderma of left foot for nine months, in an otherwise healthy individual, obstructing easy diagnosis of cutaneous tuberculosis. Diagnosis was confirmed by histopathology.     

复方倍他米松穴位注射联合口服阿维A及抗结核药物治疗皮肤结核8例

目的探讨复方倍他米松穴位注射联合口服阿维A及抗结核药物治疗皮肤结核的疗效。方法运用复方倍他米松穴位注射联合口服阿维A及抗结核药物治疗8例皮肤结核。结果4例患者4周皮损基本消退;3例患者6~8周皮损基本消退,仅1例患者11周皮损基本消退。结论复方倍他米松穴位注射联合口服阿维A及抗结核药物是治疗皮肤结核的一种有效的方法。     

疣状皮肤结核患者皮损中结核杆菌DNA的检测

本文采用PCR技术，对10例病史2年以上的疣状皮肤结核患者皮损进行了结核杆菌DNA检测，结果显示10例患者1例阳性，而作为阳性对照的4例淋巴结结核组织3例阳性，2例正常组织均为阴性。从而说明疣状皮肤结核后期组织结核菌极少或无有。     

A Case of Congenital Leukemia Cutis

Congenital leukemia is a rare condition diagnosed at birth to 6 weeks of life with an estimated incidence of 4.7 per million live births. In a review, about 25~30% of cases were well documented as leukemia cutis. We report a case of a 3-month-old infant presented with asymptomatic multiple erythematous to bluish patches and nodules, which had developed about two months ago. Biopsy of the cutaneous lesions revealed immature cells which are overall monotonous with large kidney shaped nucleus, prominent nucleoli and moderate cytoplasm. These atypical cells stained positive for leukocyte common antigen, lysozyme and CD68. With this result, a congenital leukemia cutis was diagnosed. Six months later, she underwent cord blood stem cell transplantation. Seven months after the cord blood stem cell transplantation, the bone marrow examination revealed a normal result. Leukemia can be presented in the skin, the eruption may be nonspecific and it may precede systemic involvement. The recognition is important because early diagnosis can lead to appropriate treatment, followed by better prognosis.