夹层联合修复技术在楔状缺损中的疗效

目的探讨夹层技术在楔状缺损修复中的应用疗效。方法选择有楔状缺损的病例129例,共344颗牙齿,随机分为两组,实验组167颗牙齿与对照组177颗牙齿,完成治疗后2年复查,对其疗效进行评价。结果实验组的疗效(88.7%)明显高于对照组(79.2%),两组疗效比较,差异有统计学意义(P0.05)。结论楔状缺损用夹层三明治技术修复临床疗效显著,值得应用推广。     

螺旋钉光固化复合树脂修复牙重度楔状缺损的临床观察

目的 观察用螺旋钉固位，光固化树脂修复日记本是度楔状缺损牙的临床疗效。方法 选择临床重度楔状缺损牙患，在缺损两侧牙本质区做针道后，用螺旋钉固位，光固化昨合树脂修复治疗，随访2年。结果 60例128颗楔状缺损牙，失败11颗，占8．6％；成功117颗，成功率91．4％。失败原因有充填物部分脱落，有裂缝。结论 有螺旋钉固位，光固化复合树脂修复重度楔状缺损牙，解决了以往治疗重度楔状缺损牙充填物易脱落，牙冠易折断的问题，固位效果好，美观不易脱落，疗效明显，优于其它疗法。     

光固化复合树脂修复牙齿楔状缺损体会

牙体楔状缺损是一种非龋性牙体硬组织疾病 ,因缺损的部位及形态特殊 ,故充填治疗时不易固位。作者选用光固化复合树脂治疗牙齿楔状缺损 ,现将观察结果报告如下。资料及方法　　 1.材料　选用拜耳 上海齿科有限公司的光固化复合树脂及广州华南医疗器械有限公司的光固化复合树脂。2 .临床资料　本组 180例 4 0 0颗楔状缺损牙 ,均没有牙髓病变。男性 10 2例 ,女性 78例 ,年龄 2 0～ 65岁。牙位以上下颌前牙至上下颌第一磨牙 ,每位患者患牙数均为 2～ 6颗。3.方法　按修复材料要求 ,严格遵循操作步骤 ,首先去除牙石、软垢。用小倒锥钻沿釉牙本…     

倒凹固位在楔状缺损中的应用

目的了解楔状缺损较为合适的充填方法.方法238颗牙齿被随机分组,分别用光固化复合树脂直接充填、制备倒凹固位后充填,追踪1年、3年、4年以上的成功率,并加以比较.结果制备倒凹固位后充填的成功率较光固化复合树脂直接充填明显增高.结论楔状缺损固位不佳者可先制备倒凹固位后再用光固化复合树脂充填,会达到更好的固位效果.     

夹层技术修复牙齿楔状缺损的疗效观察

目的　探讨夹层技术 ,即玻璃离子粘固剂垫底 ,复合树脂修复牙齿楔状缺损的疗效 ;方法　抽取Ⅱ～Ⅲ度楔状缺损患牙 2 11颗 ,随机分为两组。一组以夹层技术修复 (实验组 ) ,另一组以复合树脂直接充填 (对照组 ) ,观察 3年。结果　实验组疗效优于对照组。X2 =5 85 ,0 0 2 5 >P >0 0 1,两组比较有显著性差异。结论夹层技术是一种良好的修复牙齿楔状缺损的方法     

自粘结树脂水门汀3M Unicem修复楔状缺损的临床观察

目的 追踪观察、分析评价自粘结树脂水门汀(3M Unicem)在临床修复楔状缺损的临床效果.方法 78例439颗楔状缺损牙齿使用自粘结树脂水门汀(3M Unicem)修复,一年后评价其疗效.结果 成功率为96.8%.结论 自粘结树脂水门汀(3M Unicem)在临床修复楔状缺损成功率高,临床操作使用方便有待推广应用.     

口腔医院牙齿保存治疗技术获全军医疗成果一等奖

经过 2 0多年研究 ,第四军医大学口腔医院肖明振教授等在牙齿保存治疗领域取得重大进展 ,使严重病损患牙保存率由过去的 30 %提高到 70 %以上 ,该技术获得全军医疗成果一等奖 .自 2 0世纪 80年代起 ,在著名口腔内科学专家史俊南教授的指导下 ,肖明振教授等以建立牙齿保存治疗新技术为主攻方向 ,开发具有生物诱导型牙齿活髓保存修复材料 ,活髓保存率达 80 % ,功能恢复率达 93%以上 .创建了钉固位保存技术 ,并制造出固位钉成套产品 ,开展了树脂等嵌体材料的保存治牙技术 ,发展了系列桩核修复技术 ,完善了残根残冠保存治牙技术并使之系列化 ,运…     

倒凹固位在楔状缺损中的应用

目的：了解楔状缺损较为合适的充填方法。方法：238颗牙齿被随机分组，分别用光固化复合树脂直接充填、制备倒凹固位后充填，追踪1年、3年、4年以上的成功率，并加以比较。结果：制备倒凹固位后充填的成功率较光固化复合树脂直接充填明显增高。结论：楔状缺损固位不佳者可先制备倒凹固位后再用光固化复合树脂充填，会达到更好的固位效果。     

复合树脂加固位钉修复后牙大面积缺损

临床发现 ,人们重视牙齿功能的同时 ,对美观的要求越来越高 ,复合树脂修复后牙有逐渐取代银汞合金的趋势。我们于 1 997— 2 0 0 0年对后牙大面积缺损应用复合树脂同时配合固位钉修复 ,使许多过去认为必须拔除的牙齿得以保留。1　临床资料1 .1一般资料　本组 30例 ,男 1 7例 ,女 1 3例。年龄 2 0～ 6 0岁。共治疗后牙 32颗 ,其中双尖牙 2 0颗 ,(缺失 1个牙尖 ) ,磨牙 1 2颗 (缺失 1～ 2个牙尖 )。1 .2　操作方法　将牙体常规预备后 ,在所缺失部位牙面相交轴角处加自攻自断固位钉 ,一般缺失几个牙尖用几枚固位钉 ,最多不超过四枚。固位钉在修…     

箱状固位形对复合树脂修复牙齿楔状缺损疗效的影响

目的比较箱状固位形、倒凹固位形及无固位形在复合树脂修复牙齿楔状缺损治疗中,对临床疗效的影响。方法选择78例患者,334颗楔状缺损患牙,分为箱状固位形、倒凹固位形和无固位形三组。同一患者在不同象限分别采用不同方法修复患牙,自身对照,观察临床疗效两年。结果在总的修复成功率方面,箱状固位形组修复成功率96.8%,倒凹固位形组修复成功率为82.2%,无固位形组修复成功率为68.9%,三组成功率差异显著(χ2=31.898,P0.01);在修复体固位情况中,箱状固位形组修复成功率99.2%,倒凹固位形组修复成功率为94.4%,无固位形组修复成功率为83.5%,三组成功率差异显著(χ2=21.378,P0.01);在修复体边缘密合情况中,箱状固位形组修复成功率97.6%,倒凹固位形组修复成功率为87.9%,无固位形组修复成功率为85.4%,箱状固位形与倒凹固位形成功率差异显著(χ2=8.435,P=0.04),箱状固位形与无固位形成功率差异显著(χ2=11.365,P=0.01),倒凹固位形与无固位形成功率差异不显著(χ2=0.265,P0.05)。结论在复合树脂修复楔状缺损的治疗中,制备固位形对提高临床疗效是有意义的,并且箱状固位形要优于倒凹固位形。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.