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Background
Most work testing links between emotional competencies and health has focused on self-reported and/or trait assessments. However, more objective assessments of skills and knowledge may also predict health relevant outcomes.Purpose
The current study investigated whether performance-based tests of emotional knowledge and expressive skill predicted symptoms of depression and anxiety, self-reported physical symptoms, perceived health, and a range of immunoregulatory molecules.Methods
Eighty females aged 18–35 completed self-report assessments before attending a testing session in which they provided blood samples and completed performance-based assessments of expressive skill and emotional knowledge.Results
Greater expressive skill predicted better self-reported outcomes, but links to immunoregulatory molecules were mixed. Expressive skill for contempt and anger predicted higher, whereas skill for happiness predicted lower, concentrations of immunoregulatory molecules.Conclusions
These data highlight the need to extend research beyond self-reported emotional competencies and suggest that performance-based skill and knowledge metrics may be associated with health relevant outcomes.3.
Elham Baharzadeh Fereydoun Siassi Mostafa Qorbani Fariba Koohdani Neda Pak Gity Sotoudeh 《Annals of general psychiatry》2018,17(1):46
Background
The association of fruits and vegetables (FV) specific subgroups consumption and depression has not been investigated in healthy adult populations. Therefore, the aim of our study was to determine the relationship between intake of FV as well as their subgroups and depression.Methods
This cross-sectional study was conducted on 400 women attending healthcare centers. The scores of depression, anxiety, and stress were measured using the 21-item depression, anxiety and stress scales questionnaire. The participants’ anthropometric and physical activity data were collected and the 147-item semi-quantitative FFQ was used for estimating the FV intake.Results
After adjustment for confounding variables, the participants in the lower quartiles of total FV, total vegetables, total fruits, citrus, other fruits and green leafy vegetables intake were more likely to experience depression compared to those in the higher quartiles (p trend?<?0.03).Conclusion
Our findings suggest that higher intake of total FV and some of its specific subgroups might be associated with depression.4.
Purpose
Prevention of mental disorders is a rapidly growing area of research with substantial potential benefits for population health. This paper reviews the evidence base for prevention of depression, anxiety, and schizophrenia.Methods
We synthesized evidence from recent systematic reviews and meta-analyses published between 2013 and 2018 on prevention of depression, anxiety, and first-episode psychosis. We included reviews of randomized controlled trials testing psychological, psychosocial, and pharmacological preventive interventions.Results
There is good evidence that depression and anxiety can be prevented, although effect sizes are generally small. Indicated prevention of first-episode psychosis appears promising. Economic evaluations provide support for prevention of depression, anxiety, and first-episode psychosis, but more studies evaluating costs and benefits are needed to strengthen the knowledge base, particularly regarding long-term outcomes, which include chronicity of the prevented disorder, as well as later occurence of important comorbid mental and physical health problems. Promising areas for further development include internet- or computer-based prevention strategies, mindfulness-based interventions, and integration of prevention programs within occupational settings.Conclusions
A number of interventions to prevent mental disorders are efficacious. While intervention effect sizes are generally small for prevention of depression and anxiety, they may nonetheless be of significant population benefit. Using the growing evidence base to inform policy and dissemination of evidence-based prevention programs is critical for moving prevention science into real-world settings.5.
Lara Hilton Susanne Hempel Brett A. Ewing Eric Apaydin Lea Xenakis Sydne Newberry Ben Colaiaco Alicia Ruelaz Maher Roberta M. Shanman Melony E. Sorbero Margaret A. Maglione 《Annals of behavioral medicine》2017,51(2):199-213
Background
Chronic pain patients increasingly seek treatment through mindfulness meditation.Purpose
This study aims to synthesize evidence on efficacy and safety of mindfulness meditation interventions for the treatment of chronic pain in adults.Method
We conducted a systematic review on randomized controlled trials (RCTs) with meta-analyses using the Hartung-Knapp-Sidik-Jonkman method for random-effects models. Quality of evidence was assessed using the GRADE approach. Outcomes included pain, depression, quality of life, and analgesic use.Results
Thirty-eight RCTs met inclusion criteria; seven reported on safety. We found low-quality evidence that mindfulness meditation is associated with a small decrease in pain compared with all types of controls in 30 RCTs. Statistically significant effects were also found for depression symptoms and quality of life.Conclusions
While mindfulness meditation improves pain and depression symptoms and quality of life, additional well-designed, rigorous, and large-scale RCTs are needed to decisively provide estimates of the efficacy of mindfulness meditation for chronic pain.6.
Purpose of Review
The review focused on associations between temperament dimensions and clinical features in different anxiety disorders, likewise in obsessive-compulsive disorder in clinical samples of adults. A literature search was conducted in the Medline and PsycINFO databases covering the years 2010–2016. A systematic review and grading of the level of evidence for an association between temperament dimension scores and clinical features in each disorder were performed.Recent Findings
Twenty papers reporting 18 different studies were included. Five of the papers focused on panic disorder (PD), five on social anxiety disorder (SAD), three on post-traumatic stress disorder (PTSD), one on generalized anxiety disorder (GAD), three on obsessive-compulsive disorder (OCD), and an additional three papers on several anxiety disorders.Summary
The review consolidates the finding that trait anxiety, especially as assessed by Cloninger’s model or the five-factor model, is a phenomenon common to all anxiety disorders and OCD. More follow-up studies including large samples are needed to differentiate the dimensional profiles of trait anxiety in specific disorders.7.
Carla Masala Luca Saba Maria Paola Cecchini Paolo Solla Francesco Loy 《Chemosensory perception》2018,11(1):19-26
Introduction
Several studies evaluated the influence of cultural components on the Sniffin’ Sticks Identification Test in different countries. The aim of this study was to analyze the olfactory function in a large sample of healthy subjects living in Sardinia, an island known for its historic genetic isolation, in relation to different age ranges to provide new data in healthy Sardinian subjects.Methods
Olfactory perception of 161 participants (108 females and 53 males; age range 19–78 years) was assessed through three different parameters: odor detection threshold, discrimination, and identification by means of the Sniffin’Sticks Extended test (SST).Results
Our results show that young adults were generally normosmic, while in subjects over 55, a statistically significant age-related decrease of all the parameters was observed. Regarding odor identification task, a few, such as leather, apples, lemons, cloves, and pineapples, were frequently incorrectly identified by participants probably due to the similarities between the odors and distractors.Conclusion and Implications
Our data provide a comprehensive evaluation of the three olfactory components in the Sardinian population and confirm a decrease in the odor detection threshold, discrimination and identification as well as in the global TDI score in subjects over 55 years of age. These results may be useful in providing normative values for routine clinical use of the SSET in Sardinian subjects.8.
Susan W. White Grace Lee Simmons Katherine O. Gotham Caitlin M. Conner Isaac C. Smith Kelly B. Beck Carla A. Mazefsky 《Current psychiatry reports》2018,20(10):82
Purpose of Review
This synthesis of treatment research related to anxiety and depression in adolescents and adults with autism spectrum disorder (ASD) focuses on the scientific support for various forms of psychosocial interventions, useful adaptations to standard interventions, and engagement of candidate therapeutic mechanisms.Recent Findings
There is considerable evidence for the efficacy of cognitive-behavioral therapy (CBT) to treat co-occurring problems with anxiety, but there has been relatively little research on treatment of co-occurring depression. Multiple mechanisms of treatment effect have been proposed, but there has been little demonstration of target engagement via experimental therapeutics.Summary
Comorbidity between ASD and anxiety and/or mood problems is common. Although there is evidence for the use of CBT for anxiety, little work has addressed how to effectively treat depression. There is emerging support for alternative treatment approaches, such as mindfulness-based interventions. We encourage rigorous, collaborative approaches to identify and manipulate putative mechanisms of change.9.
Purpose
Our study aimed to examine the prevalence of psychiatric symptoms and their comorbidity and correlation with sleep problems among adolescent survivors 3 years after the 2013 Ya’an earthquake.Methods
A representative sample of 6132 adolescent students was analysed from 11 primary and high schools in the three counties most severely affected by the earthquake. Students were invited to complete the Pittsburgh Sleep Quality Index, Children’s Revised Impact of Event Scale-13, Short Mood and Feelings Questionnaire, the Adolescent Self-Rating Life Events Checklist, and Screen for Child Anxiety-Related Emotional Disorders.Results
Three years after this major earthquake, 1-month prevalence of mental health problems was 13.1% for PTSD, 37.3% for anxiety, and 19.8% for depression. Among the participants who reported PTSD, 71.5% also reported anxiety, and 49.7% also reported depression. At least half of those with any type of mental health problem reported concurrent sleeping problems. Specific sleep risk factors were independently associated with increased risk of PTSD, depression or anxiety. Girls were more likely than boys to exhibit symptoms of PTSD, depression or anxiety. Older adolescents were more likely to have depression and anxiety.Conclusions
Mental health problems are prevalent with high comorbidity and are associated with sleep-related problems among adolescent survivors, even years after the occurrence of a major earthquake. Nightmares and difficulty initiating sleep are independently associated with PTSD. Insufficient sleep is independently associated with anxiety and depression. Sleep-related problems may be effective targets of preventive interventions, which may need to be optimised for gender and age.10.
Purpose of Review
Mood and anxiety disorders are very commonly experienced by older adults and are becoming a growing concern due to the rapidly aging global population. Recent advances in neuroimaging may help in improving outcomes in late-life mood and anxiety disorders. The elucidation of mechanisms contributing to late-life mental health disorders may ultimately lead to the identification of novel therapeutic interventions. Alternatively, clinically validated imaging biomarkers may allow for the prediction of treatment response and identification of better therapeutic approaches in late-life mood and anxiety disorders.Recent Findings
In community samples, late-life depression and late-life generalized anxiety disorder occur up to 38 and 15%, respectively, while late-life bipolar disorder is less common and occur in approximately 0.5% of the population. There are significant challenges in treating and improving outcome in late-life mood and anxiety disorders. Time to treatment response and treatment resistance are increased in older adults. Novel neuroimaging techniques have the potential to improve diagnostic and therapeutic outcome in late-life mood and anxiety disorders either through “personalized pharmacotherapy” or through identifying dysfunction regions/networks to be subsequently used for direct interventions such as transcranial magnetic stimulation.Summary
This review will provide an overview of recent literature that substantiates the potential role of neuroimaging in clinical practice, as well as the barriers that must be overcome prior to clinical translation.11.
Objective
To review existing evidence regarding interactions between the autonomic nervous system and the immune system functions in multiple sclerosis.Methods
We reviewed the literature regarding new insights linking autonomic dysfunction to immune deregulation in multiple sclerosis, with particular focus on the specific influence of sympathetic and parasympathetic dysfunction on inflammatory and neurodegenerative processes.Results
Autonomic dysfunction is common in multiple sclerosis, representing a significant cause of disability. Several connections between pathologic immune pathways and the autonomic nervous system function were found.Conclusions
Autonomic dysfunction may enhance inflammatory and neurodegenerative pathways that are of major importance in multiple sclerosis. Autonomic dysfunction can present with highly variable manifestations. Sympathetic and parasympathetic dysfunction displays different patterns in multiple sclerosis, with specific impact on inflammation and neurodegeneration.12.
Introduction
Temperament affects olfaction in cross-sectional studies. However, it is not clear whether it is linked to olfactory development. Here we examined the links between temperament and olfaction over a nearly 2-year period, expecting that children showing higher levels of negative affectivity would exhibit greater odor awareness across repeated testing. As a subsidiary aim, we investigated whether olfactory scores differ as a function of olfactory performance at a younger age.Methods
The participants were 73 Czech children (mean age?=?5.8 years). Their olfactory abilities were assessed using the Sniffin’ Sticks, and odor awareness was evaluated with the Children’s Olfactory Behaviors in Everyday Life Questionnaire. These were reassessed 21 months later. Mothers provided information on the children’s temperament by completing the Short Form of the Children’s Behavior Questionnaire at the same interval.Results
Children’s temperament was not found to relate to olfactory development over a 21-month period. Odor identification and awareness, but not odor discrimination and threshold, differed as a function of scores achieved at an earlier age.Conclusions
Odor identification and awareness predict themselves over a 21-month period. Links between temperament and olfaction may be only beginning to form at preschool age.Implications
While this study suggests that temperament does not play a role in olfactory development, longitudinal studies over a broader timespan are needed to determine the robustness of this finding.13.
C. Manesse C. Ferdenzi M. Sabri M. Bessy C. Rouby F. Faure D. Bellil S. Jomain B. N. Landis M. Hugentobler M. Cuevas T. Hummel M. Bensafi 《Chemosensory perception》2017,10(4):104-113
Introduction
Olfaction is a highly emotionally charged sense and contributes to our quality of life, which olfactory impairment or dysosmia thus strongly impacts. The aim of the present study was to examine how olfactory deficits alter eating behavior, which is a pillar of health and well-being.Methods
Patients with quantitative smell impairment and control participants were asked to perform a series of chemosensory tasks: odor identification and ratings of odor intensity, pleasantness, familiarity, irritation, and edibility. They also filled out a detailed food questionnaire.Results
Results showed significant decrease in olfactory function in smell-impaired patients. Although no significant consequences of dysosmia were found for most aspects of food preferences and culinary habits, the patients were less attracted than controls by novel foods and tended to experience less pleasure when eating. They also used significantly more condiments such as sugar, mayonnaise, or sour cream to make their dishes tasty.Conclusions
Olfactory impairment has a clear effect on certain aspects of eating behavior.Implications
These findings highlight the compensatory mechanisms that go along with dysosmia. This also reflects the patients’ attempts to restore part of the lost flavor and its hedonic component through non-olfactory cues.14.
Ingvild Oxås Henriksen Ingunn Ranøyen Marit Sæbø Indredavik Frode Stenseng 《Child and adolescent psychiatry and mental health》2017,11(1):68
Background
Self-esteem is fundamentally linked to mental health, but its’ role in trajectories of psychiatric problems is unclear. In particular, few studies have addressed the role of self-esteem in the development of attention problems. Hence, we examined the role of global self-esteem in the development of symptoms of anxiety/depression and attention problems, simultaneously, in a clinical sample of adolescents while accounting for gender, therapy, and medication.Methods
Longitudinal data were obtained from a sample of 201 adolescents—aged 13–18—referred to the Department of Child and Adolescent Psychiatry in Trondheim, Norway. In the baseline study, self-esteem, and symptoms of anxiety/depression and attention problems were measured by means of self-report. Participants were reassessed 3 years later, with a participation rate of 77% in the clinical sample.Results
Analyses showed that high self-esteem at baseline predicted fewer symptoms of both anxiety/depression and attention problems 3 years later after controlling for prior symptom levels, gender, therapy (or not), and medication.Conclusions
Results highlight the relevance of global self-esteem in the clinical practice, not only with regard to emotional problems, but also to attention problems. Implications for clinicians, parents, and others are discussed.15.
Thomas Hummel Han-Seok Seo Roberto Pellegrino Stefan Heilmann 《Chemosensory perception》2017,10(4):114-118
Aim
Ortho- and retronasal olfaction represent two aspects of a shared sensory system yet evoke different sensations. The differences between ortho- and retronasal olfaction have triggered a number of studies during the past years, which pointed towards a decreased sensitivity to odors presented through the retronasal olfactory pathway. Especially intensity was reported to be lower after retronasal olfactory stimulation. The aim of this study was to investigate how this compares to activation at the level of the olfactory epithelium in humans.Methods
Trigeminal (CO2) and olfactory (H2S, phenylethyl alcohol) stimuli were presented ortho- and retronasally. Electro-olfactograms (EOG) in response to chemosensory stimulation were recorded in 10 participants (6 women, 4 men, mean age 23.4 years).Results
Typical EOGs were demonstrable after either orthonasal or retronasal stimulation across the stimulus qualities. Overall, EOG amplitudes to retronasal stimulation were smaller when compared to those to orthonasal stimulation, but a significant difference was obtained only in phenylethyl alcohol (p?=?0.048).Conclusions
The present data indicate that the perceptual differences between ortho- and retronasal olfaction may start at the level of the olfactory epithelium. The data support the idea that the intensity of physically identical stimuli is lower after retronasal stimulation compared to orthonasal stimulus presentation for both olfactory and trigeminal stimuli.Implications
The current electrophysiological results are in line with reported differences in psychophysical properties of retro- and orthonasal stimulations meaning that different sensations are elicit through these two channels although the same molecule is presented.16.
Purpose of Review
The early medical literature on mental health outcomes following abortion is fraught with methodological flaws that can improperly influence clinical practice. Our goal is to review the current medical literature on depression and other mental health outcomes for women obtaining abortions.Recent Findings
The Turnaway Study prospectively enrolled 956 women seeking abortion in the USA and followed their mental health outcomes for 5 years. The control group was comprised of women denied abortions based on gestational age limits, thereby circumventing the major methodological flaw that had plagued earlier studies on the topic.Summary
Rates of depression are not significantly different between women obtaining abortion and those denied abortion. Rates of anxiety are initially higher in women denied abortion care. Counseling on decision-making for women with unintended pregnancies should reflect these findings.17.
Purpose of Review
To focus on the clinical and behavioral presentation of anhedonia in mood disorders, as well as the differences and commonalities in the underlying neurocircuitry.Recent Findings
Evidence suggests that depression is characterized by hypofunction of the reward system, while bipolar disorder manifests dysregulation of the behavioral activation system that increases goal-directed reward behavior. Importantly, strong evidence does not exist to suggest significant differences in anhedonia severity between depressed unipolar and bipolar patients, suggesting that there are more nuanced fluctuations in reward processing deficits in bipolar patients depending on their state. Both euthymic unipolar and bipolar patients frequently report residual reward dysfunction, which highlights the potential of reward processing deficits that give rise to the clinical symptom of anhedonia to be trait factors of mood disorders; however, the possibility that therapies are not adequately treating anhedonia could also explain the presence of residual symptoms.Summary
Reward processing represents a potential diagnostic and treatment marker for mood disorders. Further research should systematically explore the facets of reward processing in at-risk, affected, and remitted patients.18.
Introduction
Common brain areas play a role in processing both personality and odor, while personality theory predicts that olfactory performance should vary according to personality traits. The Big Five model of personality is considered a gold standard measure but has yet to be directly applied in investigations linking personality and olfactory responses. Moreover, olfactory measures commonly used in personality studies are usually rudimentary sensory performance indices such as thresholds as opposed to higher-order perceptual and psychological metrics.Methods
This cross-sectional study examined the relationship between comprehensive measures of personality and perceptual responses to odors. Personality was measured using a comprehensive test of the Big Five model of personality, while olfactory responses included identification, pleasantness, perceived intensity, and familiarity. Odors were presented using the Sniffin’ Sticks test.Results
Small to moderate correlations were noted between aspects of personality and response to odor, even after controlling for participant (N = 74) characteristics such as age and gender. Regression analyses indicated that, overall, odor familiarity co-varies the most with aspects of personality.Conclusions and Implications
Responses to olfactory stimuli are moderated by specific personality dimensions. This finding is consistent with approach and avoidance motivational models of personality.19.
Sasha MacNeil Sonya S. Deschênes Warren Caldwell Melanie Brouillard Thien-Thanh Dang-Vu Jean-Philippe Gouin 《Annals of behavioral medicine》2017,51(6):912-924
Background
High-frequency heart rate variability (HF-HRV) reactivity was proposed as a vulnerability factor for stress-induced sleep disturbances. Its effect may be amplified among individuals with high trait worry or sleep reactivity.Purpose
This study evaluated whether HF-HRV reactivity to a worry induction, sleep reactivity, and trait worry predict increases in sleep disturbances in response to academic stress, a naturalistic stressor.Method
A longitudinal study following 102 undergraduate students during an academic semester with well-defined periods of lower and higher academic stress was conducted. HF-HRV reactivity to a worry induction, trait worry using the Penn State Worry Questionnaire, and sleep reactivity using the Ford Insomnia Stress Reactivity Test were measured during the low stress period. Sleep disturbances using the Pittsburgh Sleep Quality Index were assessed twice during the lower stress period and three times during the higher stress period.Results
Greater reductions in HF-HRV in response to the worry induction predicted increases in sleep disturbances from the lower to the higher academic stress period. Trait worry moderated this association: individuals with both higher trait worry and greater HF-HRV reactivity to worry had larger increases in stress-related sleep disturbances over time, compared to participants with lower trait worry and HF-HRV reactivity. A similar, but marginally significant effect was found for sleep reactivity.Conclusion
This study supports the role of HF-HRV reactivity as a vulnerability factor for stress-induced sleep disturbances. The combination of high trait worry and high HF-HRV reactivity to worry might identify a subgroup of individuals most vulnerable to stress-related sleep disturbances.20.
Dzenana Kartal Nathan Alkemade Maurice Eisenbruch David Kissane 《Social psychiatry and psychiatric epidemiology》2018,53(9):931-941