共查询到20条相似文献,搜索用时 15 毫秒
1.
S. Scott Sutton Joseph Magagnoli James W. Hardin Ling-I Hsu Anne Beaubrun Sunil Majethia 《Current medical research and opinion》2020,36(10):1635-1642
Abstract
Background
Tenofovir disoproxil fumarate (TDF)-based regimens have been associated with impaired kidney function and loss of bone mineral density among patients living with HIV (PLWH). We assess the association between TDF exposure and the odds of chronic kidney disease (CKD) and osteoporotic fracture in HIV patients. 相似文献2.
ABSTRACT
Background
The purpose of our research was to recommend the initial tacrolimus dosage for Chinese pediatric patients undergoing kidney transplantation based on population pharmacokinetics and pharmacogenetics. 相似文献3.
Charalampos Loutradis 《Expert opinion on pharmacotherapy》2020,21(10):1201-1217
ABSTRACT
Introduction
Hypertension is the most common co-morbidity in patients with chronic kidney disease (CKD), with prevalence gradually increasing across CKD Stages to the extent that about 90% of end-stage renal disease (ESRD) patients are hypertensives. Several factors contribute to blood pressure (BP) elevation and guide the therapeutic interventions that should be employed in these patients. 相似文献4.
ABSTRACT
Introduction
Hypertension is highly prevalent in patients with end-stage kidney disease on hemodialysis and is often not well controlled. Blood pressure (BP) levels before and after hemodialysis have a U-shaped relationship with cardiovascular and all-cause mortality. Although antihypertensive drugs are recommended for patients in whom BP cannot be controlled appropriately by non-pharmacological interventions, large-scale randomized controlled clinical trials are lacking. 相似文献5.
ABSTRACT
Introduction
Direct oral anticoagulants (DOACs) are widely prescribed nowadays. Available DOACs are renally eliminated to some extent and need dose adjustment in patients with kidney dysfunction. Cockcroft-Gault (CG) formula has been used to estimate creatinine clearance in DOACs trials. Nowadays, Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) are preferred equations for estimating glomerular filtration rate (GFR). We reviewed studies that simulated DOACs dosing in patients with atrial fibrillation by MDRD, CKD-EPI, and CG. 相似文献6.
Gates B. Colbert Dhwanil Patel Edgar V. Lerma 《Expert review of clinical pharmacology》2020,13(6):563-570
ABSTRACT
Introduction
Hyperkalemia is a chronic and life-threatening electrolyte disorder that affects millions of patients around the world with decreased kidney function, hypertension, and heart failure. Recently newer oral potassium-binding agents have been approved for clinical use, as an alternative to the decades long use of sodium polystyrene sulfonate. This review will focus on the patiromer and its use in reducing hyperkalemia. 相似文献7.
ABSTRACT
Introduction
Hyperkalemia, defined as serum potassium level > 5.0 mEq/l, is associated with serious cardiac dysrhythmias, sudden death and increased mortality risk. It is common in patients with chronic kidney disease (CKD), diabetes (DM) and heart failure (HF), particularly in those treated with the renin-angiotensin-aldosterone system (RAAS) inhibitors or potassium-sparing diuretics. Although these drugs have documented renal and cardiac protective benefits, frequent hyperkalemia associated with their use often dictates administration of suboptimal doses or their discontinuation altogether. Treatment for chronic hyperkalemia in these settings has been challenging; however, the recent introduction of two new potassium-binding resins has revolutionized our approach to treating hyperkalemia. 相似文献8.
ABSTRACT
Introduction
Lefamulin is a novel antibiotic that belongs to the pleuromutilin class with excellent activity against all microorganisms, including atypical pathogens, that cause community-acquired pneumonia (CAP). 相似文献9.
C. Neill Epperson Keziah Cook Deepshekhar Gupta Anita Chawla Paul E. Greenberg 《Current medical research and opinion》2020,36(10):1707-1716
Abstract
Objective
To quantify the economic burden of postpartum depression (PPD) that accrues to commercially insured households in the year following childbirth. 相似文献10.
Abstract
Objective
To investigate the effect of high-dose systemic steroids on retinal tissues and the effectiveness of ozone (O3) therapy. 相似文献11.
Giovanni Grandi Martina Caroli Laura Cortesi Angela Toss Giovanni Tazzioli Fabio Facchinetti 《Expert opinion on drug safety》2020,19(8):1025-1030
ABSTRACT
Introduction
Risk-reducing-salpingo-oophorectomy (RRSO) inevitably leads BRCA mutation carriers to premature menopause. 相似文献12.
Onur Karadag Murat Kocamaz Metin Dastan Serap Ozturk Durur 《Cutaneous and ocular toxicology》2020,39(3):233-236
Abstract
Purpose
To investigate the impact of oral isotretinoin therapy in choroidal thickness, central macular thickness (CMT), and retinal nerve fibre layer (RNFL) thickness using optical coherence tomography (OCT). 相似文献13.
Dominik Lautsch Kristy Iglay Lingfeng Yang Neha Bansal Riddhi Markan Niranjan Kathe 《Current medical research and opinion》2020,36(10):1583-1589
Abstract
Objective
To assess the level of glycemic control among type 2 diabetes patients on sodium-glucose cotransporter 2 inhibitor (SGLT2i) and metformin dual therapy. 相似文献14.
Yingkai Xu Yingkai Li Hua Shen Beibei Zhang Qi Zhao Yujing Cheng 《Current medical research and opinion》2020,36(10):1643-1652
Abstract
Objective
To explore the clinical effect and radial remodeling of transradial slender 7?Fr sheath for left main bifurcation disease (LM bifurcation). 相似文献15.
ABSTRACT
Introduction
Immune checkpoint inhibitors (ICIs) have rapidly changed the treatment landscape, demonstrating dramatic clinical efficacy in various cancers. 相似文献16.
Shilan Mozaffari Shekoufeh Nikfar Marzieh Daniali 《Expert opinion on pharmacotherapy》2020,21(6):701-707
ABSTRACT
Introduction
Constipation is common in patients with Parkinson’s disease (PD). Due to the considerable negative outcomes of constipation, significant efforts have been made to prevent and manage chronic constipation in these patients. 相似文献17.
Abstract
Context
α-Hederin, a potent bioactive compound of Pulsatilla chinensis (Bunge) Regel (Ranunculaceae), has many pharmacological uses, but its effect on cancer cell metabolism is still unclear. 相似文献18.
Darko Mitrovic Richard Folkeringa Nic Veeger Eric van Roon 《Current medical research and opinion》2020,36(10):1571-1576
Abstract
Aims
We sought to investigate the magnitude of minor bleeding and identify risk factors for minor bleeds during non-vitamin-K antagonist oral anticoagulant (NOAC) therapy. 相似文献19.
Abstract
Objective
To examine the relationship between hemoglobin A1c (HbA1c) reduction and healthcare costs among patients with type 2 diabetes (T2D). 相似文献20.
Mohamad Moussa Mohamed Abou Chakra Despoina Sryropoulou Athanasios Dellis 《Expert opinion on pharmacotherapy》2020,21(12):1431-1448
ABSTRACT