中医药对放化疗减毒增效的研究

恶性肿瘤放化疗常出现程度不一的毒副作用,以致影响了它们的治疗效果.中西医结合治疗减轻了癌症患者在放化疗中的近期毒副作用,提高了疗效及生活质量,远期提高癌症患者的生存率、延长了生存时间.实验研究证明中医药防治放化疗毒副作用的科学性越来越强.中医药对放化疗减毒增效作用已形成完整有效的证治体系,中西医结合治疗癌瘤是今后防治肿瘤的重要途径和方法.     

博士答疑

中医真的能延长肿瘤患者的生存时间吗?中医药延长肿瘤患者的生存时间,现在已有多项循证医学证据作为支撑。如中国中医科学院广安门医院的一项多中心、大样本临床研究表明,癌症患者化疗后配合中药治疗,病情进展明显缓慢,对化疗     

中西合璧 才有希望

中医药能否治疗癌症?中医药治疗癌症的优势是什么?如何充分发挥中医药在中西医结合综合治疗癌症中的重要作用?这些问题都是我们数十年来探索的主要内容。从我40多年的临床经验和研究来看,中医药治疗癌症的重点应该是中西医结合,采取中西医取长补短,相辅相成的策略。中医药在整个癌症综合治疗中有重要作用。上世纪七十年代初,我们看到大量疼痛病人在化疗中,由于化学药物抑制骨髓的造血功能,引起的白细胞、血小板下降和贫血,常使化疗中途停止,因而我们根据患者所表现的脾虚肾亏、气血双亏的证候,制定了健脾补肾、补气养血的方剂,称之为"生血汤"(生芪、太子参、黄精、鸡血藤、枸杞子、菟丝子、     

中医药综合治疗模式在晚期癌症治疗中的临床应用

晚期癌症综合治疗的模式可以分为以化疗为主的西医综合治疗模式和以中医药为主的中医药综合治疗模式。本文根据药物经济学原理、疗效和毒副反应等，探讨晚期癌症的中医药综合治疗模式及其依据。     

癌症放化疗不良反应的中医药治疗

手术、放化疗作为癌症的主要治疗手段虽有一定疗效，但其不良反应较多。中医药疗法作为一种辅助治疗的方法，对放化疗不良反应的预防及治疗有较好的疗效。本文总结中医药疗法在癌症放化疗不良反应中的应用进展。     

糖尿病与癌症相关联的机制研究

糖尿病与癌症是对公众健康产生严重影响的常见疾病。流行病学证据表明糖尿病患者某些癌症的发生及死亡风险增加, 主要包括胰腺癌、肝癌、结直肠癌、肾癌、膀胱癌、女性乳腺癌及子宫内膜癌等。糖尿病与癌症之间可能存在直接和间接的关联, 两者间直接的生物学机制可能是高胰岛素血症、高血糖和慢性炎症, 两者存在的共同危险因素包括年龄、性别、种族、肥胖、饮食、体育锻炼、吸烟和酒精。本文综述了糖尿病与癌症相关联机制的研究证据。      

中西医结合治疗对肿瘤患者生存质量的影响

随着生物一心理一社会医学模式的建立，改善和提高癌症患者生存质量已成为肿瘤治疗方案设汁中日益受到重视的问题。临床医生在关注肿瘤局部的同时，更要顾全整个机体，包括患者的心理、精神及其社会适应能力，使患者和社会真正受益。中医药在恶性肿瘤综合治疗中有其独特的作用，我国应用中西医结合治疗肿瘤已有40多年历史。大量的临     

老年癌症患者应用抗癌药的问题(综述)

癌症发病率随年龄的增长而上升,癌症已成为老年人的主要死因之一。老年癌症治疗中的一个重要方面是采取包括化疗在内的综合治疗。过去虽已明确化疗对常见的老年癌症如胃肠道癌、肺癌等均有缓解症状,延长生存期的治疗作用,但治疗方案大多是从姑息治疗的角度来考虑的。这一方面是由于老年生理功能的衰退,会使药物的吸收、代谢、分布和排泄有所改变,对药物的顺应性有所     

中医药抗癌的免疫机理

近年来,中医、中西医结合治疗癌症取得了令人瞩目的成就,中医治疗癌症的机理颇为复杂,中医药对荷瘤机体的免疫调节作用是其较为重要也颇受肿瘤工作者重视的治癌机理之一。作为治疗癌症的重要中医治则,扶正培本、活血化淤、清热解毒治疗方法的     

癌症相关性疲乏的研究现状和进展

癌症是严重危害我国人民健康的重大慢性疾病。癌症相关性疲乏是癌症患者最常见的且持续最长的症状之一,严重影响癌症患者的生活质量,甚至会导致抗肿瘤治疗中断,缩短患者生存时间。目前,国内外都发布了一系列关于癌症相关性疲乏的指南和专家共识。本文将结合目前国内外的指南、专家共识及现有的研究证据,对癌症相关性疲乏的定义、诊断、治疗及进展作一总结。     

中国癌症相关性疲乏临床实践诊疗指南（2021年版）

癌症已成为严重威胁中国人群健康的主要公共卫生问题之一。研究发现，癌症与疲乏关系密切，癌症相关性疲乏是癌症患者最为常见的伴随症状。癌症相关性疲乏严重影响癌症患者的工作、社会关系、情绪、日常活动和生活质量，可导致部分患者治疗中断，甚至影响癌症患者的生存时间。但目前中国尚无相关的指南可用于指导癌症相关性疲乏的临床诊治，中华医学会肿瘤学分会肿瘤支持康复治疗学组专家对癌症相关性疲乏的研究进展进行归纳总结，旨在及时传递重要信息，指导临床实践。本指南主要涵盖癌症相关性疲乏的定义、流行病学、临床表现、发病机制、影响因素、中医证候类型、筛查、临床评估及中西医结合治疗等方面，为癌症相关性疲乏临床诊疗提供参考依据，将有助于临床医师对癌症相关性疲乏患者进行规范化治疗，改善中国癌症相关性疲乏患者的临床结局。     

中医药参与肿瘤综合治疗模式现状与分析

中医药在肿瘤综合治疗中有独特的地位和优势,中医、西医诊疗理念与评价内容的日趋一致性为中医药参与肿瘤综合治疗奠定了有利的理论基础。中医药参与肿瘤不同阶段的治疗形成了维持治疗、巩固治疗、强化治疗以及序贯治疗等不同模式。全文针对中医药参与综合治疗肿瘤的模式进行探讨,以期为今后临床研究提供一定的理论基础。     

Traditional Chinese medicine, acupuncture, and other alternative medicines for prostate cancer: an introduction and the need for more research.

There are several other alternative medicines apart from vitamins and minerals that the clinician should be aware of because they have grown in popularity in other fields of medicine. In time, these therapies should impact the arena of urologic oncology. Traditional Chinese Medicine, which includes acupuncture, is an area that has received some attention. The theory behind it can be quite daunting because it is so different from the theory behind Western Medical Science. In addition, exactly how acupuncture can be applied to a patient and its potential use in prostate cancer need to be addressed. Other herbal therapies for the patient experiencing symptoms related to a localized cancer diagnosis also need to be evaluated. St John's Wort for depression and Kava for anxiety are two examples of herbal alternatives that some prostate patients are inquiring about. Finally, Ginkgo biloba has received a great deal of attention in the media for erectile dysfunction, but there is a dearth of evidence in this area and the information that already exists can be misleading until further studies are conducted. Also, it is imperative that additional studies be performed in all of the above subjects as they relate to prostate cancer, but a general survey on alternative medicine use in urologic diseases is needed first before an adequate review of the most popular therapies can be published.     

浙江省肿瘤医院2008~2012年中医门诊就诊患者分析

[目的]分析浙江省肿瘤医院中医门诊就诊患者情况,为有效地配置医疗资源提供依据。[方法]回顾性分析中医门诊数据,对2008~2012年中医门诊就诊患者数据进行分析。[结果]2008~2012年中医门诊人次排在前5位的依次为肺恶性肿瘤（19.26%）、乳腺恶性肿瘤（17.03%）、肠恶性肿瘤（10.39%）、胃恶性肿瘤（8.99%）和鼻咽恶性肿瘤（6.96%）;40~69岁年龄段中医门诊人次占76.31%;就诊患者医保占60.25%、自费占39.75%。[结论]我院中医门诊人次整体呈逐年上升趋势。就诊患者中肺癌、乳腺癌和肠癌居多。40~69岁中年人、女性及医保患者居多。     

乳腺癌古代中医文献考略

乳腺癌是女性高发病恶性肿瘤。中医古代的文献对于乳腺癌在病因、病机、治则、方药方面都有很深入的认识,对于现代临床医学有极大的参考价值,且现代临床试验与动物实验表明,中西药结合治疗乳腺癌疗效明显优于单纯应用西药组。现对古代文献中与乳腺癌相关的记载进行梳理,以期为临床医师提供更开阔的辨治思路。     

气虚证与肺癌临床病理特征的关系研究

目的 研究中医气虚证和肺癌患者的性别、病理类型、组织分化程度、TNM分期的关系.方法 根据中医虚证辨证标准,对110例患者进行辨证,将患者划分为有气虚及无气虚两组,然后用χ2检验和logistic回归方法分析患者气虚证与肺癌各项临床病理特征之间的关系.结果 气虚证和肺癌患者的性别、组织分化程度、TNM分期等有关;Logistic回归分析表明肺癌气虚证与组织分化程度、TNM分期独立相关.结论 中医气虚证和肺癌的生物学行为相关,晚期患者和组织分化程度差的患者易发生气虚证.     

加减补阳还五汤治疗肿瘤化疗后神经损伤的临床观察

目的:探讨加减补阳还五汤治疗化疗后神经损伤的临床疗效。方法:选择在我院门诊和住院肿瘤化疗后出现周围神经损伤的患者41例,随机分为A组,维生素B6 和维生素B12 治疗组;B组,加减补阳还五汤治疗组;C组,维生素B6 和维生素B12 再联合加减补阳还五汤治疗组。结果:中药加减补阳还五汤疗效与西药维生素B6 和维生素B12 疗效相当,中西药联合治疗疗效明显高于单纯中药或西药的疗效。结论:加减补阳还五汤对化疗后所致神经损伤具有良好的疗效。     

Integration of Chinese medicine into supportive cancer care: a modern role for an ancient tradition.

Recent evidence suggests that many traditional Chinese medical therapies are effective for the supportive care of cancer patients. This is a review of some of the published literature (indexed in Medline) and our own practical experience. It is not intended to be a systematic review, but does provide various levels of evidence which support further research into a developing model of integrative care. The holistic approach of Traditional Chinese Medicine (TCM) may be integrated into conventional Western Medicine to supplement deficiencies in the current biomedical model. The philosophy of TCM proposes novel hypotheses which will support the development of a science-based holistic medicine.     

The potential of a person-centered approach in caring for patients with cancer: a perspective from the UCLA center for East-West medicine

BACKGROUND: Evolving patient preferences as well as an expanding evidence base for commonly used complementary and alternative medicine therapies for patients with cancer have led to inroads by integrative medicine into clinical oncology. Traditional Chinese medicine (TCM) has been used in conjunction with conventional biomedicine in the prevention and treatment of cancer in China for several decades. METHODS: The authors, through select review of the existing literature and by drawing on clinical experience, describe a person-centered approach to care of patients with cancer that incorporates TCM concepts and techniques. Two cases are used to illustrate how this approach might address unmet needs and enhance quality of life for patients with cancer. RESULTS: TCM's emphasis on a comprehensive understanding of imbalance in various systems and resultant compromise of homeostatic reserve as well as its ability to treat them with distinctive therapeutic modalities can add unique value to the overall management of the patient with cancer. CONCLUSIONS: TCM can be used adjunctively to improve quality of life and functional status during a patient's struggle with cancer. An approach integrating both medicines that is guided by scientific evidence, safety, and patient preferences has the potential to improve modern oncologic care.     

Chinese medicine and biomodulation in cancer patients--Part one

Traditional Chinese Medicine (tcm) may be integrated with conventional Western medicine to enhance the care of patients with cancer. Although tcm is normally implemented as a whole system, recent reductionist research suggests mechanisms for the effects of acupuncture, herbs, and nutrition within the scientific model of biomedicine. The health model of Chinese medicine accommodates physical and pharmacologic interventions within the framework of a body-mind network. A Cartesian split does not occur within this model, but to allow for scientific exploration within the restrictions of positivism, reductionism, and controls for confounding factors, the components must necessarily be separated. Still, whole-systems research is important to evaluate effectiveness when applying the full model in clinical practice. Scientific analysis provides a mechanistic understanding of the processes that will improve the design of clinical studies and enhance safety. Enough preliminary evidence is available to encourage quality clinical trials to evaluate the efficacy of integrating tcm into Western cancer care.