共查询到20条相似文献,搜索用时 31 毫秒
1.
María Prado Belén Martín-Castilla Alejandro Espejo-Reina José Miguel Serrano-Fernández Ana Pérez-Blanca Francisco Ezquerro 《Knee surgery, sports traumatology, arthroscopy》2013,21(2):476-484
Purpose
In anterior cruciate ligament reconstruction with looped soft-tissue grafts, an interference screw is frequently used for tibial fixation. This study compared three alternatives thought to improve the initial mechanical properties of direct bioabsorbable interference screw fixation: suturing the graft to close the loop, adding a supplementary staple, or increasing the oversize of the screw diameter relative to the bone tunnel from 1 to 2 mm.Methods
Twenty-eight porcine tibiae and porcine flexor digitorum profundus tendons were randomized into four testing groups: a base fixation using 10-mm-diameter screw with open-looped graft, base fixation supplemented by an extracortical staple, base fixation but closing the looped graft by suturing its ends, and base fixation but using an 11-mm screw. Graft and bone tunnel diameters were 9 mm in all specimens. Constructs were subjected to cyclic tensile load and finally pulled to failure to determine their structural properties.Results
The main mode of failure in all groups was pull-out of tendon strands after slippage past the screw. The sutured graft group displayed significantly lower residual displacement (mean value reduction: 47–67 %) and higher yield load (mean value increase: 38–54 %) than any alternative tested. No other statistical differences were found.Conclusions
Suturing a soft-tissue graft to form a closed loop enhanced the initial mechanical properties of tibial fixation with a bioabsorbable interference screw in anterior cruciate ligament reconstructions using a porcine model, and thus, this may be an efficient means to help in reducing post-operative laxity and early clinical failure. No mechanical improvement was observed for an open-looped tendon graft by adding an extracortical staple to supplement the screw fixation or by increasing the oversize of the screw to tunnel diameter from 1 to 2 mm. 相似文献2.
Schneppendahl J Thelen S Gehrmann S Twehues S Eichler C Koebke J Windolf J Hakimi M Wild M 《Knee surgery, sports traumatology, arthroscopy》2012,20(10):2088-2093
Purpose
Displaced tibial eminence fractures require surgical fixation in order to obtain a stable knee joint. Suture fixation with FiberWire® seems to be the most favorable therapeutic option. Biomechanical studies show failure of this technique most commonly due to a suture cutout with subsequent fracture of the tibial eminence fragment. The goal of this study is to compare the biomechanical properties of three different techniques of suture fixation using FiberWire®.Methods
Bone mineral density was evaluated in 18 human knee specimens by pqCT, and three similar groups were formed. A standardized anterior tibial eminence fracture was created, and suture fixation was performed using one of three different techniques in 6 specimens each. Cyclic and destructive testing was conducted.Results
Significant differences between the three techniques could be shown neither in the cycles needed to achieve a steady state nor in a failure load or initial stiffness. Almost all specimens failed by suture cutout.Conclusion
The presented modification of the existing technique for suture fixation of tibial eminence fractures did not lead to an increased initial stability nor did it lower the rate of suture cutout. All tested suture techniques showed comparable initial stiffness and failure load. 相似文献3.
Philipp Forkel Peter Foehr Johannes C. Meyer Elmar Herbst Wolf Petersen Peter U. Brucker Rainer Burgkart Andreas B. Imhoff 《Knee surgery, sports traumatology, arthroscopy》2017,25(2):403-410
Purpose
The purpose of the present study was to biomechanically compare three different posterior meniscal root repair techniques. Transtibial fixation of a posterior meniscus root tear (PMRT) combined with an anterior cruciate ligament (ACL) reconstruction via one tunnel only shows similar properties in terms of cyclic loading and load to failure compared with direct anchor fixation.Methods
Twenty-eight porcine knees were randomly assigned to 4 groups (n = 7 each): (1) native posterior meniscal root, (2) suture anchor repair, (3) refixation via a tibial ACL tunnel in combination with an interference screw fixation of the ACL graft, and (4) refixation via a tibial ACL tunnel in combination with an interference screw fixation of the ACL graft with an additional extracortical button fixation. The four groups underwent cyclic loading followed by a load-to-failure testing. Construct elongation during 1000 cycles, dynamic stiffness, attenuation, maximum force during load-to-failure testing, and failure mode were recorded.Results
All reconstructions showed a significant lower maximum load (p < 0.0001) compared with the native meniscal root. The elongation for the transtibial fixation via the ACL tunnel without an additional extracortical backup fixation was significantly higher compared with the suture anchor technique (p < 0.0001). The additional use of a backup fixation led to similar results compared with the anchor repair technique.Conclusion
The transtibial refixation of the meniscal root can be combined with an ACL reconstruction using the same tibial bone tunnel. However, an additional extracortical backup fixation is necessary. This might avoid a slippage of suture material and a failure of meniscus root fixation.4.
Petri J. Sillanpää Essi Salonen Harri Pihlajamäki Heikki M. Mäenpää 《Knee surgery, sports traumatology, arthroscopy》2014,22(10):2414-2418
Purpose
To define medial patellofemoral ligament (MPFL) injury characteristics at the patellar attachment and clinical outcome in patients with primary traumatic patellar dislocation and MPFL avulsion injury at the patella.Methods
Magnetic resonance imaging (MRI) was used to assess patients with primary (first-time) patellar dislocation and MPFL injury at the medial margin of the patella. Fifty-six patients with patellar attachment MPFL injury were enrolled in the study. Thirteen patients underwent surgical fixation of the avulsed MPFL and patellar medial margin osteochondral fracture, and the remaining patellar MPFL injures were treated nonoperatively. Forty-four patients were evaluated clinically at median four (range 1–10) years after patellar dislocation. The follow-up included evaluation of recurrent patellar instability, subjective symptoms, and functional limitations.Results
Three types of patellar MPFL injuries were found; type P0 with ligamentous disruption at the patellar attachment, type P1 with bony avulsion fracture from the medial margin of the patella, and type P2 with bony avulsion involving articular cartilage from the medial facet of the patella. Of the patellar MPFL avulsion injuries that underwent initial surgical fixation, two patients (2/13) reported an unstable patella at follow-up. Fifty-five per cent (17/31) of patellar MPFL avulsion injuries that were treated nonoperatively had recurrent patellar instability (n.s.). The median Kujala score was 90 for patellar avulsion with surgical fixation and 86 for patellar avulsion without surgical fixation (n.s.).Conclusion
Patellar attachment MPFL injury showed three different patterns, classified as types P0, P1, and P2. MRI can be used to assess the injury pattern. Patellar MPFL avulsion injuries do not benefit from acute surgical repair compared with nonsurgical treatment. Type P2 patellar MPFL avulsion includes an osteochondral fracture that may require surgical fixation.Level of evidence
Prognostic study, Level III. 相似文献5.
Michael Stalder Mazda Farshad Jess G. Snedeker Dominik C. Meyer 《Knee surgery, sports traumatology, arthroscopy》2013,21(3):584-588
Purpose
Interference screw fixation of hamstring tendon grafts in bone has to overcome the challenges that tendons have a slippery surface and viscoelastically adapt under pressure. As the typical failure mode of the graft is to slip past the interference screw, it was hypothesized that the position and configuration of the graft end may be of influence on the fixation strength.Methods
Different configurations of the graft ending and its effect to primary fixation with interference screws after viscoelastic adaptation were tested in six groups: I: graft and the screw inserted at the same depth, II/III: the graft overlaps the tip of the screw (interference screw of 28 and 19 mm in length, respectively), IV: strengthening of the graft ending with additional suture knots, V: Endopearl, respectively, and VI: effect of partial retraction of the screw after excessive insertion. In vitro tests were performed with fresh calf tendon grafts and interference screws in bone tunnels (fresh porcine distal femur) all of 8 mm in diameter.Results
The relative position of the graft ending to the tip of the interference screw thereby was recognized as a significant factor on pullout forces. Further strengthening at the graft endings with additional suture knots or an Endopearl device could improve primary hold as well.Conclusions
Better fixation strength is achieved if the tip of interference screw does not extend past the end of a tendon graft. Enforcement of the tendon end with sutures or an implant can further improve fixation. 相似文献6.
M. Ettinger M. Petri K. T. Haag S. Brand A. Dratzidis C. Hurschler C. Krettek M. Jagodzinski 《Knee surgery, sports traumatology, arthroscopy》2014,22(9):2040-2047
Purpose
The success of reconstructions of the posterior cruciate ligament (PCL) mainly depends on the fixation strength of the tendon–bone interface. Reliable data about the mechanical characteristics of PCL fixation techniques are sparse. The aim of this study was to investigate the biomechanical properties of different femoral PCL fixation techniques.Methods
Fresh human cadaver quadriceps (Q) and hamstring (H) tendons were harvested and fixed into porcine femora with a press-fit fixation suturing the tendon over a bone bridge (group A), a novel implant post-fixation (group B) or an interference screw fixation (group C). Each group consisted of 10 specimens. The constructs were cyclically stretched and eventually loaded until failure. Elongation during cyclic loading, stiffness, failure mode and maximum failure load was evaluated.Results
Elongation during cyclical loading was significantly larger between the 1st and the 20th cycle than between the 20th and the 500th cycle in all groups (p < 0.05). Maximum failure load was 409 ± 71 (336–517) N in group QA, 456 ± 58 (347–510) N in group QB, 548 ± 116 (400–798) N in group QC, 472 ± 114 N (316–676 N) in group HA, 494 ± 98 N (371–668 N) in group HB and 498 ± 87 N (391–687 N) in group HC (significantly higher for QB compared to QA, p < 0.05).Conclusion
This is the first study investigating the biomechanical properties of femoral PCL fixations. Implant-free fixation techniques like press-fit or post-fixations are able to withstand equal biomechanical forces compared to interference screw fixation. The novel fixations described in this study can be considered as a reliable alternative for the reconstruction of PCL using either hamstring or quadriceps tendons. 相似文献7.
Werner Anderl Philipp R. Heuberer Brenda Laky Bernhard Kriegleder Roland Reihsner Josef Eberhardsteiner 《Knee surgery, sports traumatology, arthroscopy》2012,20(12):2559-2566
Purpose
The purpose of our study was to evaluate the initial fixation strength of bridging techniques compared to other suture techniques for rotator cuff repair using a biomechanical animal model, which incorporated pretesting of intact tendons.Methods
Seventy-six fresh bovine shoulders were used for testing seven suture configurations including simple suture (SS), mattress suture (MS), Mason-Allen (MA), modified double row (mDR), SpeedBridge (SpB), SpeedBridge with medial fixation (mSpB), and double-mattress SutureBridge (dmSuB) techniques. Cyclic loading was performed with all intact bone-tendon complex before (pretest) and after repair of the tendon (main test) at the level of 10 and 180 N at 100 Hz with displacement-controlled ramps of ±33 mm/s. The pretest was stopped after 200 cycles. For the main test, the loading scheme was continued for a maximum of 500 cycles or until failure.Results
The mean elongation of all 76 intact tendons measured at the pretest was 3.8 ± 0.6 mm (2.4–5.4 mm). No differences of gap formations at the 1st cycle were detected between SS, MS, MA, and mDR. SpB showed significant higher gap formations compared to all other suture techniques (p = 0.001). No significant differences were detected between mSpB and dmSuB, whereas both techniques were significant different when compared to the other groups (p < 0.05).Conclusions
In this study, results showed that bridging techniques with medial fixations have superior initial repair strength compared to other suture techniques. Knowledge of initial fixation strength of rotator cuff repair techniques may be of informative value to the surgeon. 相似文献8.
Purpose
We evaluated with magnetic resonance imaging (MRI) the degradation and osteointegration features of a new type of bioabsorbable interference (BioRCI) screw composed of poly-L-lactic acid and hydroxyapatite (PLLA-HA) used for tibial graft fixation in anterior cruciate ligament (ACL) reconstruction.Materials and methods
Thirty-one patients underwent arthroscopic surgery for ACL reconstruction using doubled gracilis and semitendinosus tendons fixed to the tibial tunnel with PLLA-HA (BioRCI-HA) screws. Two groups of patients were evaluated, one group 10–13 months after surgery and the other after 30–40 months. The standard knee ligament evaluation form of the International Knee Documentation Committee (IKDC) was used for clinical assessment and MRI for the radiological assessment.Results
MRI after 10–13 months revealed findings referable to healing and integration of the bone-graft-screw system, findings that disappeared at later follow-up examinations. The BioRCI-HA screw remained constantly visible in all patients, although with changes in signal intensity over time.Conclusions
BioRCI-HA screws allow adequate primary stability and superior osteoconduction and biocompatibility in comparison with plain PLLA screws. The absence of ferromagnetic artefacts allows accurate MRI follow-up and adequate evaluation of ligament synovialisation, screw degradation and graft osteointegration. 相似文献9.
Lawrence Camarda Giuseppe Pitarresi Salvatore Moscadini Giuseppe Marannano Antonino Sanfilippo Michele D’Arienzo 《Knee surgery, sports traumatology, arthroscopy》2014,22(5):1040-1046
Purpose
A suture passed along the part of the graft that will be inserted into the femoral tunnel is widely used by surgeons, because it could prevent the graft sliding on the femoral fixation device during pulling from the tibial side. The aim of this study was to evaluate the biomechanical effects of suturing the intratunnel femoral part of the graft during an anterior cruciate ligament (ACL) reconstruction.Methods
Bovine digital extensor tendons and tibias were harvested from 20 fresh-frozen mature bovine knees ranging in age from 18 to 24 months. Quadruple-strand bovine tendons were passed through the tibial tunnel and secured distally with a bioabsorbable interference screw. In one half of all grafts (N = 10), the looped-over part of the graft was sutured in a whipstitch technique over a distance of 30 mm (Group 1). In one half of all grafts (N = 10), the looped-over part was left free from any suture (Group 2). The grafts were preconditioned at 50 N for 10 min, followed by cyclic loading at 1 Hz between 50 N and 250 N for 1,000 cycles. Load-to-failure test was then carried out at a rate of 1 mm/s.Results
There was no statistically significant difference between mean stiffness at pullout and yield load between the two groups. In all specimens on Group 1, failure occurred following to partial breaking and then slipping of the tendons between the screw and the tunnel. Concerning Group 2, in six cases failure occurred as described for Group 1 specimens. In the remaining four cases, failure occurred entirely through the ligament mid-substance.Conclusions
Suturing in a whipstitch fashion the femoral portion of the graft doesn’t affect the mechanical proprieties of the ACL graft. When suspension fixation device is used, suturing the looped-over part of the graft could be helpful in order to provide equal tension in all of the strands of the graft at time of tibial fixation. 相似文献10.
Seong Hwan Kim Young Bok Jung Min Ku Song Sang Hak Lee Ho Joong Jung Han Jun Lee Hyoung Seok Jung Hawa-Tahir Siti 《Knee surgery, sports traumatology, arthroscopy》2014,22(9):2085-2093
Purpose
The purpose of this study was to evaluate the stability and functional outcomes of anterior cruciate ligament (ACL) reconstruction by tensioning of the ACL remnant using pull-out sutures compared with ACL double-bundle reconstruction.Methods
Forty-four patients were included in single-bundle reconstruction with remnant tensioning group (Group 1), and 56 patients were included in the double-bundle reconstruction group (Group 2). The remnant tissue was tensioned to the direction of posterolateral bundle, which unrelated to the type of remnant bundle. Objective knee stability was evaluated by anterior stress radiography, KT-1000 and lateral pivot shift tests. The Tegner activity scale, International Knee Documentation Committee and OrthopädischeArbeitsgruppeKnie scoring systems were used for clinical evaluation.Results
No statistically significant intergroup differences were observed in mechanical stability and clinical results (n.s). However, surgical time of remnant tensioning group is shorter than double-bundle reconstruction group (P = 0.005).Conclusion
Remnant tensioning suture with single-bundle reconstruction could be used with positive results as good as double-bundle technique if a good ACL remnant was found bridging the femur and tibia, rather than debride or damage to the remnant tissue during operation.Level of evidence
Retrospective, comparative cohort study, Level IV. 相似文献11.
Peter W. Ferlic Patrick Sadoghi Georg Singer Tanja Kraus Robert Eberl 《Knee surgery, sports traumatology, arthroscopy》2014,22(4):893-897
Purpose
Avulsion fractures of the ischial tuberosity are rare sports injuries typically occurring in young athletes. Their misdiagnosis may lead to chronic pain or disability. The aim of this study is to report a retrospective series of patients sustaining a fracture of the ischial tuberosity and to propose decision guidelines.Methods
The mechanism of accident, the diagnostic management, the mode of treatment and outcome after avulsion fractures of the ischial tuberosity in adolescents were analysed.Results
Thirteen patients (1 female and 12 males) with a median age of 15 years (range 13–16 years) with an avulsion fracture of the ischial tuberosity were included. Twelve of these patients suffered from sports injuries leading to the avulsion fracture. Five of our patients with a displacement of >15 mm were treated operatively. The outcome was excellent in cases of acute presentation and osteosynthesis. Eight patients were treated conservatively: four of them showed a displacement of <15 mm and had an excellent outcome; and the other four patients had a displacement of >15 mm. Two of those patients had excellent outcome with regular bone healing, the remaining two patients developed pseudarthrosis associated with a good outcome.Conclusion
The present paper shows that in patients with displacement of <15 mm, conservative treatment yields excellent results and early operative intervention should be considered in physically active patients with displacement of >15 mm.Level of evidence
IV. 相似文献12.
Aníbal Debandi Akira Maeyama Yuichi Hoshino Shigehiro Asai Bunsei Goto Patrick Smolinski Freddie H. Fu 《Knee surgery, sports traumatology, arthroscopy》2013,21(3):589-595
Purpose
Conventional transtibial technique fails to restore the rotational knee stability in spite of successful anterior laxity, while anatomic anterior cruciate ligament reconstruction using the anteromedial portal technique has been developed expecting better rotational kinematics because of closer reproduction of the native anterior cruciate ligament anatomy. However, the rotational instability after those two procedures has not been fully examined especially in terms of dynamic component of the rotational stability. The purpose was to assess the effect of anatomic versus non-anatomic tunnel placement on rotational knee stability after anterior cruciate ligament reconstruction using triaxial accelerometry.Methods
Sixteen porcine knees underwent a manual pivot-shift test at four different conditions: (1) anterior cruciate ligament intact, (2) anterior cruciate ligament deficient, (3) non-anatomic transtibial reconstruction, and (4) anatomic anteromedial portal reconstruction. The three-dimensional acceleration of knee motion during the pivot-shift test was recorded using a triaxial accelerometer.Results
Both anterior cruciate ligament reconstructions decreased significantly the acceleration of the pivot-shift test from the increased level in the anterior cruciate ligament-deficient condition. However, the transtibial technique fails to reach the intact level of acceleration, while the anteromedial portal technique reduced the acceleration to even less than the intact level.Conclusion
The transtibial anterior cruciate ligament reconstruction could not restore the dynamic rotational stability of the intact knee, whereas the anteromedial portal technique restored the dynamic rotational stability closer to the intact level.Level of evidence
III. 相似文献13.
14.
Theelen A Martens J Bosmans G Houben R Jager JJ Rutten I Lambin P Minken AW Baumert BG 《Strahlentherapie und Onkologie》2012,188(1):84-90
Purpose
The goal was to provide a quantitative evaluation of the accuracy of three different fixation systems for stereotactic radiotherapy and to evaluate patients?? acceptance for all fixations.Methods
A total of 16?consecutive patients with brain tumours undergoing fractionated stereotactic radiotherapy (SCRT) were enrolled after informed consent (Clinical trials.gov: NCT00181350). Fixation systems evaluated were the BrainLAB? mask, with and without custom made bite-block (fixations S and A) and a homemade neck support with bite-block (fixation B) based on the BrainLAB? frame. The sequence of measurements was evaluated in a randomized manner with a cross-over design and patients?? acceptance by a questionnaire.Results
The mean three-dimensional (3D) displacement and standard deviations were 1.16?±?0.68?mm for fixation S, 1.92?±?1.28 and 1.70?±?0.83?mm for fixations A and B, respectively. There was a significant improvement of the overall alignment (3D vector) when using the standard fixation instead of fixation A or B in the craniocaudal direction (p?=?0.037). Rotational deviations were significantly less for the standard fixation S in relation to fixations A (p?=?0.005) and B (p?=?0.03). EPI imaging with off-line correction further improved reproducibility. Five out of 8?patients preferred the neck support with the bite-block.Conclusion
The mask fixation system in conjunction with a bite-block is the most accurate fixation for SCRT reducing craniocaudal and rotational movements. Patients favoured the more comfortable but less accurate neck support. To optimize the accuracy of SCRT, additional regular portal imaging is warranted. 相似文献15.
Jens Dargel Klaus Burkhart Dietmar Pennig Gregor Stein Peer Eysel Lars Peter Müller 《Knee surgery, sports traumatology, arthroscopy》2013,21(2):450-455
Purpose
Open surgical reconstruction of the lateral ulnar collateral ligament is the standard treatment for symptomatic posterolateral rotatory instability of the elbow. It involves dissection and retraction of the lateral elbow muscles, which have been shown to be secondary stabilizers of the lateral elbow. We introduce a new muscle-protecting technique for single-strand lateral ulnar collateral ligament reconstruction and report on the isometry and primary stability when compared with a conventional muscle-splitting procedure. It was hypothesized that percutaneous lateral ulnar collateral ligament reconstruction provided isometry over the range of motion and that stability was comparable with a conventional open procedure.Methods
In sixteen human cadaver arms, the intact and the lateral collateral ligament complex-deficient situation was tested. Open lateral ulnar collateral ligament reconstruction was performed using a single-strand palmaris graft with humeral and ulnar tenodesis screw fixation. Posterolateral rotational stability was compared with a new reconstruction method, which percutaneously places a single-strand palmaris graft with humeral and ulnar tenodesis screw fixation.Results
Both open and percutaneous lateral ulnar collateral ligament reconstruction provided isometry over the range of motion and restored posterolateral stability to that of the intact situation. No significant differences between open and percutaneous reconstruction were found.Conclusions
Percutaneous lateral ulnar collateral ligament reconstruction aims to preserve the lateral elbow muscles and to minimize soft tissue dissection. It has been shown that in an in vitro setup, this new procedure provides isometry over the range of motion and sufficiently restores posterolateral rotatory stability. 相似文献16.
目的:探讨膝关节后内侧微创入路结合锚钉固定治疗后交叉韧带胫骨止点撕脱性骨折的疗效.方法:总结我院自2008年1月至2010年1月,对16例后交叉韧带胫骨止点撕脱性骨折经膝后内侧微创入路行复位和锚钉固定的手术效果.结果:手术时间20~40 min,平均28 min.随访14~36个月,平均18个月,X线片显示所有骨折均复... 相似文献
17.
Sai-Chuen Fu Wai-Hang Cheng Yau-Chuk Cheuk Tsui-Yu Mok Christer G. Rolf Shu-Hang Yung Kai-Ming Chan 《Knee surgery, sports traumatology, arthroscopy》2013,21(5):1226-1233
Purpose
Initial graft tensioning is important in anterior cruciate ligament reconstruction (ACLR), but its effect on graft healing is still not clear. Since all previous animal studies on graft tensioning used bone–patellar tendon–bone, this study aimed to investigate the effect of initial graft tensioning on ACLR using tendon graft.Methods
Fifty-five Sprague–Dawley rats underwent ACLR using flexor digitorum longus tendon graft. A constant force of 2 or 4 N was applied during graft fixation. At 0, 2, and 6 weeks, knee samples were harvested (n = 6) for static knee laxity test and graft pull-out test. Histological examination was performed at 2 and 6 weeks post-injury (n = 4).Results
At time zero, knee laxity was restored by ACLR with 2 or 4 N tensioning as compared to ACL-deficient group (p < 0.001), and the 4 N group exhibited a better restoration as compared to 2 N group (p = 0.031). At week 2 post-operation, the 4 N group still exhibited a better restoration in knee laxity (p = 0.001) and knee stiffness (p = 0.002) than the 2 N group; the graft pull-out force (p = 0.032) and stiffness (p = 0.010) were also higher. At week 6 post-operation, there was no significant difference between the 2 and 4 N group in knee laxity and graft pull-out strength. Histological examination showed that the beneficial effect of higher initial graft tension may be contributed by maintenance of graft integrity at mid-substance and reduction in adverse peri-graft bone changes in the femoral tunnel region.Conclusions
A higher initial graft tension favours the restoration of knee laxity and promotes graft healing in ACLR using free tendon graft in the rat model. 相似文献18.
David Figueroa Maximiliano Espinosa Rafael Calvo Maximiliano Scheu Alex Vaisman Marcela Gallegos Paulette Conget 《Knee surgery, sports traumatology, arthroscopy》2014,22(5):1196-1202
Purpose
The objective of this study was to determine whether using mesenchymal stem cells (MSC) seeded in a collagen type I scaffold would be sufficient to regenerate the torn anterior cruciate ligament (ACL).Methods
Anterior cruciate ligament transection was performed on both knees in 10 New Zealand rabbits and then repaired with as follows: suture alone (suture-treated group, n = 6), suture associated with collagen type I scaffold (collagen type I scaffold-treated group, n = 8) or suture associated with autologous MSC seeded on collagen type I scaffold (MSC/collagen type I scaffold-treated group, n = 6). At 12-week post-intervention, the animals were killed and the ACLs were characterised macroscopically and histologically. Data of the 3 groups were against normal ACL (normal group, n = 10).Results
Macroscopic observation found that in MSC/collagen type I scaffold group, 33 % of specimens showed a complete ACL regeneration, with a tissue similar to the normal ACL. Regeneration was not observed in the group treated with suture alone or associated with collagen type I scaffold without cells. In the latter, only a reparative attempt at the ends was observed. Histological analysis of the regenerated ACL showed a tissue with organised collagen and peripheric vessels.Conclusions
These results provide evidence that the use of MSC seeded in a collagen type I scaffold in the treatment of ACL injuries is associated with an enhancement of ligament regeneration. This MSC-based technique is a potentially attractive tool for improving the treatment of ACL ruptures. 相似文献19.
Andrea Ferretti Edoardo Monaco Ludovico Caperna Tommaso Palma Fabio Conteduca 《Knee surgery, sports traumatology, arthroscopy》2013,21(3):690-695
Purpose
Due to the increasing number of primary anterior cruciate ligament (ACL) reconstructions, the need for revision surgery has risen. The aim of this study was to evaluate the use of contralateral doubled semitendinosus and gracilis tendon (DGST) for revision anterior cruciate ligament reconstruction.Methods
Twelve patients undergoing revision ACL reconstruction with hamstring tendon were examined at an average follow-up of 3 years. All patients underwent a thorough subjective and objective evaluation, which included a KT-1000 arthrometric evaluation, and a radiographic examination.Results
Subjective evaluation yielded a median score of 5.5 (range 2–9) on the Tegner activity scale. The mean Lysholm score was 95 (SD 9.5), and the mean subjective IKDC 2000 score was 95.4 (SD 7.8). At physical examination, a negative Lachman test was found in ten patients; one patient had a positive Lachman test with a firm end-point, and one other patient had a clearly positive Lachman test. Two patients had a grade 1+ on pivot shift testing. Only 1 patient showed a side-to-side difference more than 5 mm at the maximum manual KT-1000 arthrometer. Three patients (25 %) showed initial signs of osteoarthritis.Conclusions
The results of the study show that the use of hamstring tendons harvested from the unaffected knee represents a valid option for revision surgery following a failed primary ACL reconstruction using DGST grafts.Level of evidence
IV. 相似文献20.
关节镜下Ethibond缝线联合Endobutton钢板治疗膝前交叉韧带下止点撕脱骨折 总被引:1,自引:0,他引:1
目的探讨关节镜下Ethibond缝线联合Endobutton钢板固定治疗前交叉韧带下止点撕脱性骨折的可行性及近期疗效。方法2010年7月~2012年8月对23例膝前交叉韧带下止点撕脱骨折患者行关节镜下Ethibond韧带缝线联合Endobutton带袢钢板止点重建术,男性16例,女性7例;年龄25~66岁,平均38.5岁。术中使用Ethibond缝线,横穿撕脱骨折腱骨联合区,经韧带两侧胫骨骨隧道拉到胫骨内下方,固定在胫骨前方Endobutton钢板上。结果手术时间45—70min,平均55min。23例均随访11—24个月,平均17.5个月。术后6个月,所有骨折均获愈合,未出现骨折移位及膝关节不稳;Lysholm膝关节功能评分86~97分。结论关节镜下韧带缝线联合Endobutton带袢钢板治疗膝前交叉韧带下止点撕脱骨折,操作简便,效果可靠。 相似文献