自发性低颅压综合征9例分析

自发性低颅压综合征(Spontaneous intracranial hypotension syndrome,SIHS)是指一组原因不明的颅内压低于70mmH2O的临床症候群,易造成误诊.对我院l996-01～2003-12收治9例分析如下.     

自发性低颅压综合征14例分析

自发性低颅压综合征（SIH）是指原因不明、颅压低于70mmH2O、预后良好的综合征，在临床上并不少见，但因重视不够，极易被误诊。现将我院2000—01／2007—12收治的14例分析如下。     

原发性低颅压综合征12例临床分析

目的:探讨原发性低颅压综合征的临床表现、诊断及治疗方法.方法:对12例原发性低颅压综合征临床资料进行回顾性分析.结果:12例均有体位性头痛表现,于坐位、站位及活动时头痛加剧,平卧位时头痛减轻或缓解,疼痛位于前额部和颞枕部,有时波及整个头颅及后颈部,多为钝痛,可伴有恶心、头晕、颈强直等,脑脊液压力均低于60 mmH2O.本组根据临床表现及医技检查结果确诊为原发性低颅压综合征.结论:对以头痛为主诉就诊的患者,要仔细询问病史,认真查体,及时完善脑脊液等检查,避免误诊.     

自发性低颅压综合征误诊2例分析

由于自发性低颅压综合征（SIH）在临床上较为少见,故容易造成误诊,现将我科近年来误诊的2例分析如下。     

原发性低颅压综合征16例临床分析

目的：探讨原发性低颅压综合征（primary intracranial hypotension syndrome）的临床特点、诊断及治疗。方法：回顾性分析16例原发性低颅压综合征患者的临床资料。结果：本组患者均有体位性头痛、恶心、呕吐,伴有眩晕4例、耳鸣2例、颈项强直15例。16例行腰穿检查,脑脊液（CSF）压力均〈70mmH2O。13例患者CSF中红细胞数有不同程度升高,1例患者为血性CSF。治疗以大剂量补充生理盐水为主,2例腰穿时行CSF置换,均痊愈。结论：体位性头痛是低颅压综合征的临床特征,腰穿CSF测压检查可确诊。本病一般预后较好。     

低颅压综合征12例分析

目的:探讨低颅压综合征(SIH)的临床特点和影像学改变。方法:回顾性分析12例SIH患者的临床及影像资料。结果:所有患者均有体位性头痛;头颅CT报告2例硬膜下积液;3例行头颅MRI检查示硬脑膜增厚;全部患者采用内科综合疗法,均痊愈。结论:SIH的临床表现多样,体位性头痛是特征性症状,腰穿脑脊液(CSF)及头颅MRI检查具有诊断价值;本病预后良好,但少数并发硬膜下血肿。     

老年人自发性低颅压综合征临床分析

目的：研究老年人自发性低颅压综合征（SIH）的临床特点。方法：分析SIH（25例）及继发性低颅压综合征（7例）的临床表现,并对腰穿、影像学检查结果进行比较。结果：SIH以体位性头痛为主要表现;继发性组以局灶体征明显。腰穿示SIH组脑脊液（CSF）主白细胞增多,继发性组主蛋白增多。SIH影像学检查可见广泛脑膜硬化;继发性组见脑实质灶。结论：了解SIH的临床特点有助于提高SIH临床确诊率。     

自发性低颅压综合征10例临床分析

自发性低颅压综合征(spontaneous intracranial hyptension，SIH)是指原因不明、预后良好、颅压低于70mmH2O(1mmH2O=0．0098kPa)的一组征候群。临床以坐位或直立时头痛、恶心呕吐及颈项强直为主要表现，平卧时头痛很快消失或减轻为特征。此综合征既往国内报道较少，随着对本病的不断认识和研究，近年来临床上发现本患者的病例不断增多，现将我院2000～2003年收治的10例并文献分析报道如下。     

原发性低颅压综合征12例分析

现将我院2000-2006年间收治的原发性低颅压综合征12例的临床资料分析如下。[第一段]     

原发性低颅压综合征20例分析

1996-01／2006-01我院收治原发性低颅压综合征（PIH）患者20例，分析如下。 1 临床资料 1．1 一般资料 本组男8例，女12例，年龄26～65岁。急性起病18例，亚急性起病2例。     

自发性低颅压综合征2例报告并文献复习

目的：探讨自发性低颅压综合征（Spontaneous Intracranial Hypotension,SIH）的临床和影像学特征,提高诊治水平。方法：对自发性低颅压2例报告并文献复习。结果：2例自发性低颅压均有典型的直立性头痛以及头颅核磁共振（MRI）增强扫描所示的硬脑膜广泛异常强化。其中1例虽然腰椎穿刺并无颅内压降低,但颈部MRI抑脂相提示脑脊液外漏。结论：脑脊液漏可能是导致自发性低颅压的主要原因,腰椎穿刺测压不是诊断的唯一依据,典型的临床表现和影像学征象有助于诊断,内科保守治疗无效时应考虑硬膜外血液补片法治疗。     

Atypical Spontaneous Intracranial Hypotension With a Head‐Shaking Headache

Spontaneous intracranial hypotension (SIH) is typically characterized by orthostatic headache; however, various atypical manifestations of SIH have been reported recently. We report here the case of a 46‐year‐old man with headache secondary to SIH, which was nonorthostatic, triggered only when the patient shook his head. We suggest that SIH should be suspected in patients with headache induced by head‐shaking, even without orthostatic features, especially when the headache is accompanied by other symptoms commonly associated with SIH.     

Caring for Patients With Spontaneous Intracranial Hypotension

Spontaneous intracranial hypotension (SIH) is a form of intracranial hypotension that often lacks uniformity in its presentation on physical assessment and radiological imaging studies among patients. SIH can be mistaken for a number of other unrelated conditions, and because it is also quite rare, many health care providers and patients are not familiar with this condition. These factors make SIH difficult to recognize and diagnose. This article seeks to bring greater awareness to health care professionals about SIH to direct patients affected by SIH to more appropriate and timely care. This work also offers suggestions for management of patients receiving an epidural blood patch, a common treatment for SIH.     

腰椎穿刺在动脉瘤性蛛网膜下腔出血诊断中的价值

目的 探讨腰椎穿刺在动脉瘤性蛛网膜下腔出血(SAH)诊断中的价值.方法 回顾分析13例经头CT为阴性诊断而腰椎穿刺诊断为SAH,数字减影血管造影(DSA)确诊颅内动脉瘤的患者的临床资料.结果 腰椎穿刺诊断SAH阳性率为100%.结论 腰椎穿刺诊断动脉瘤性SAH具有重要意义.     

Spontaneous intracranial hypotension: case report

Spontaneous intracranial hypotension is a well defined entity, however it is characterised by a relevant clinical heterogeneity. The main feature is orthostatic headache, often accompanied by other symptoms. The diagnosis is easily made in the presence of orthostatic headache, excluding an obvious aetiology of low cerebrospinal fluid (CSF) pressure, and often there is no evidence of direct or indirect CSF leak.     

Cerebral Venous Thrombosis in Spontaneous Intracranial Hypotension

Background and Objective.— The occurrence of cerebral venous thrombosis has been reported among patients with spontaneous intracranial hypotension, but a causal relationship has not been clearly established. We reviewed our experience with spontaneous intracranial hypotension and cerebral venous thrombosis and we reviewed the relevant literature to evaluate the relationship between these 2 entities. Methods.— We reviewed the medical records and imaging studies of a consecutive group of patients with spontaneous intracranial hypotension evaluated at a tertiary care center between 1/1/2001 and 12/31/2007. The main search strategy was a systemic review of journal articles in MEDLINE (1966 to January 2008). Results.— Among 141 patients with spontaneous intracranial hypotension, 3 (2.1%) were also diagnosed with cerebral venous thrombosis. Among these 3 patients and the 17 reported in the literature there were 11 men and 9 women with a mean age of 39.5 years. Radiographic or clinical evidence for spontaneous intracranial hypotension preceding cerebral venous thrombosis was found in most patients, while there was no evidence for cerebral venous thrombosis preceding spontaneous intracranial hypotension in any patient. Eight (40%) of the 20 patients were found to have a change in their headache pattern believed to be due to the development of cerebral venous thrombosis. Complications of cerebral venous thrombosis, eg, cerebral venous infarction, occurred in 8 patients (40%). Conclusions.— Spontaneous intracranial hypotension is a risk factor for cerebral venous thrombosis, but cerebral venous thrombosis is found in only about 2% of patients with spontaneous intracranial hypotension. A change in headache pattern is not a reliable predictor of the development of cerebral venous thrombosis in patients with spontaneous intracranial hypotension.     

Treatment Outcomes in Spontaneous Intracranial Hypotension: Do Epidural Blood Patches Stop the Leaks?

Abstract:   Spontaneous intracranial hypotension (SIH) is a postural headache syndrome unrelated to dural puncture. Because of the increasing failure of epidural blood patch (EBP) to relieve headache in SIH, we retrospectively investigated the epidemiological features and treatment outcomes in 55 cases of SIH. The study population was stratified by age and sex; continuous variables were compared for differences by t -tests; categorical variables were compared by Chi-squared analysis or Fisher exact tests. Significant differences were identified by P values of 0.05 or less. The mean age of the study population was 44 ± 12 years with a female to male ratio of 1.3:1.0. Men presented with subdural hematomas ( P  = 0.001) more often than women. Meningeal enhancement on contrast magnetic resonance imaging (MRI) was the most consistent radiographic finding. Radionuclide cisternography (RC) demonstrated thoracolumbar dural leaks in 16 of 22 patients. EBP failures were more common in patients aged 40 and younger than in older patients ( P  = 0.003). Postural headache from SIH was not uniformly responsive to EBP, and had significant comorbidities, especially in men. The management of postural headache in SIH by other techniques to restore brain position and cerebrospinal fluid dynamics should be investigated.     

Iatrogenic Intracranial Hypotension: A Case Study

Cerebrospinal fluid (CSF) leaks due to spinal procedures are commonly reported and can result in a condition known as intracranial hypotension. In rare cases, this can lead to a life-threatening situation if not properly diagnosed and treated. This case study discusses a rapidly decompensating patient that was found to have a CSF leak after an epidural placement for childbirth and made a full recovery after treatment with an epidural blood patch.