Antibodies against common antigen of epithelial tissue of human thymus and skin epidermis in myasthenia gravis

Experiments by the indirect immunofluorescence method showed that the sera of patients with myasthenia gravis in a high percentage of cases react with cells of epithelial type of the human thymus. By absorption of the sera with suspensions of epidermal cells and tissue homogenates of several human organs it was shown that the antigen of the epithelial cells with which the sera of patients with myasthenia react belongs to the epidermal heteroorganic antigens of the thymus, i.e., it is common to the epithelium of the thymus and the epidermis of the human skin. The presence of antibodies against epithelial tissue cells of the thymus in the blood serum of patients with myasthenia gravis suggests that in this disease an immunopathological process takes place, aimed against thymus tissue antigens, including against the heteroorganic structures of its epithelium.Laboratory of Streptococcal Infections, N. F. Gamaleya Institute of Epidemiology and Microbiology, Academy of Medical Sciences of the USSR. Laboratory of Clinical Pathophysiology, Institute of General Pathology and Pathological Physiology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR O. V. Baroyan.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 83, No. 1, pp. 60–62, January, 1977.     

Ultrastructural analysis of preparations impregnated with silver salts

Tissue sections from the juxtacardial segments of the pulmonary veins and venae cavae of dogs impregnated with silver salts by the Kampos method were studied. An electron-microscopic investigation showed that the reduced silver adsorbed by the tissue of the impregnated preparations had a granular structure, with single granules ranging from 30 to 400 Å in diameter. The largest granules were found in the axoplasm of myelinated and unmyelinated nerve fibers, and the small granules were in various cellular and fibrous components of the tissue substrate. As a rule no silver granules were found in the substance of the myelin sheath. The patterns of adsorption and distribution of the silver granules in the impregnated preparations explain the morphological manifestations of the phenomenon of argentophilia.B. I. Lavrent'ev Laboratory of Neurohistology, P. K. Anokhin Institute of Normal Physiology, Academy of Medical Sciences of the USSR. Laboratory of General Pathology and Experimental Therapy, Institute of General Pathology and Pathophysiology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR A. M. Chernukh.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 81, No. 1, pp. 81–84, January, 1976.     

Chemotactic function of skin fibroblasts in patients with amyloidosis

Department of Internal Medicine and Occupational Diseases, and Problem Laboratory for Nephrology, Central Research Department, I. M. Sechenov First Moscow Medical Institute. Institute of Medical Genetics, Academy of Medical Sciences of the USSR. Institute of Crystallography, Academy of Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR N. P. Bochkov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 109, No. 6, pp. 578–580, June, 1990.     

Recombinant env protein in diagnosis of AIDS

Laboratory of Associated Infections, N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Academy of Medical Sciences of the USSR. Laboratory of Physiology of Viruses, D. I. Ivanovskii Institute of Virology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR V. M. Zhdanov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 105, No. 5, pp. 577–578, May, 1988.     

Trypsin activity in chyme and juxtamural layer of mucus in experimental blocking of the Brunner's glands region of the rat duodenum

Department of Histology and Department of Operative Surgery, I. M. Sechenov Moscow Medical Academy Laboratory of Electron Microscopy, Institute of Nutrition, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR I. V. Sudakov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 112, No. 11, pp. 542–545, November, 1991.     

Trajectories of red blood cell flow in microvessels studied by automatic image analysis

Laboratory of Physiology and Pathology of the Cerebral Circulation, I. S. Beritashvili Institute of Physiology, Academy of Sciences of the Georgian SSR, Tbilisi. Laboratory of General Physiology of the Microcirculation, Research Institute of General Pathology and Pathological Physiology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR M. M. Khananashvili.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 109, No. 4, pp. 343–344, April, 1990.     

Action of cisplatin and cycloplatam on the rat kidney

Laboratory of Evolution of the Kidney and Water and Salt Metabolism, I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Academy of Sciences of the USSR, Leningrad. All-Union Oncologic Scientific Center, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR, I. P. Ashmarin.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 108, No. 7, pp. 52–54, July, 1989.     

Antistressor effect of dalargin in rats with immobilization stress

Laboratory of Experimental Surgery, A. V. Vishnevskii Institute of Surgery, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR M. I. Kuzin.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 111, No. 6, pp. 617–619, June, 1991.     

Blood flow velocity distribution in terminal microvascular bed of rat mesentery

Department of Physiology of Man and Animals, M. V. Lomonosov Moscow State University. Laboratory of General Pathology of the Microcirculation, Research Institute of General Pathology and Pathological Physiology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR I. P. Ashmarin.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 107, No. 5, pp. 515–517, May, 1989.     

Platelet guanylate cyclase in human diabetics

Laboratory of Mechanisms of Regulation of Enzyme Activity, Research Institute of Medical Enzymology, Academy of Medical Sciences of the USSR. Laboratory of Biochemistry and Pathology of Metabolism, Institute of Experimental Endocrinology and Hormone Chemistry, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR I. P. Ashmarin.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 107, No. 3, pp. 300–302, March, 1989.     

Sympathetic neurons in the superior cervical ganglion are more numerous in SHR and Wistar-Kyoto rats than in wistar rats

Department of Physiology of Man and Animals, Faculty of Biology, Moscow University. Laboratory of Pathophysiology, Research Institue of Pediatrics, Academy of Medical Sciences of the USSR. Department of General Biology, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR M. Ya. Studenikin.) Translated from Byullet en' Éksperimental'noi Biologii i Meditsiny, Vol. 108, No. 11, pp. 620–622, November, 1989.     

Effect of injection of delta sleep-inducing peptide into the substantia nigra on the Parkinsonian syndrome in rats

Laboratory of General Pathology of the Nervous System, Research Institute of General Pathology and Pathophysiology, Academy of Medical Sciences of the USSR, Moscow. Department of Pathophysiology, N. I. Pirogov Odessa Medical Institute. Institute of Bioorganic Chemistry, Academy of Sciences of the USSR, Moscow. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 109, No. 2, pp. 119–121, February, 1990.     

Activation of lipid peroxidation during painful emotional stress

Accumulation of primary and secondary lipid peroxidation (LPO) products were investigated by ultraviolet spectrophotometry and fluorescence of Schiff bases in various tissues of Wistar rats subjected to painful emotional stress (PES). The quantity of LPO products was shown to increase under the influence of PES mainly in the heart, and also significantly, although to a lesser degree than in the heart, in skeletal muscles and brain. The increase in content of hydroperoxides in all the organs studied was smaller than the increase in the content of fluorescent Schiff bases, the end products of LPO.Laboratory of Pathophysiology of the Heart, Institute of General Pathology and Pathological Physiology Academy of Medical Sciences of the USSR. Laboratory of Physical Chemistry of Biomembranes, M. V. Lomonosov Moscow University. Laboratory of Pathological Physiology, Institute of Psychiatry, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR A. M. Chernukh.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 88, No. 10, pp. 404–406, October, 1979.     

Anticonvulsant effects of neurotropin

Department of Normal Physiology, N. I. Pirogov Odessa Medical Institute. Department of Normal Physiology, I. M. Sechenov First Moscow Medical Institute. Laboratory of General Pathology of the Nervous System, Research Institute of General Pathology and Pathophysiology, Academy of Medical Sciences of the USSR, Moscow. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 111, No. 1, pp. 49–52, January, 1991.     

Prevention of arrhythmias in conscious animals during acute ischemia with the aid of a serotonin analog

Laboratory of Pathophysiology of the Heart, Research Institute of General Pathology and Pathological Physiology, Academy of Medical Sciences of the USSR. Department of Organic Chemistry, D. I. Mendeleev Moscow Chemical Engineering Institute. S. Ordzhonikidze All-Union Pharmaceutical Chemical Research Institute, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR I. K. Shkhvatsabaya.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 106, No. 10, pp. 410–412, October, 1988.     

Mineralization of ground substance of new bone tissue in mouse marrow organ cultures

Laboratory of Immunomorphology, N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Academy of Medical Sciences of the USSR, Moscow. Laboratory of Medical Biophysics, Institute of Chemical Physics, Academy of Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR S. V. Prozorovskii.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 106, No. 11, pp. 614–616, November, 1988.     

Interaction between bradykinin,morphine, and naloxone at the sensomotor cortical unit level

The effects of bradykinin, morphine, and naloxone applied by microiontophoresis on sensomotor cortical neurons were studied in waking rabbits. Bradykinin increased the discharge frequency of most neurons. Morphine inhibited unit activity. Against the background of morphine, bradykinin had no activating action. Naloxone abolished the depriming effect of morphine and restored the response of the neurons to bradykinin. It is concluded that bradykinin interacts with opiate receptors in the brain.Laboratory of Molecular Neurophysiology and Biochemistry, P. K. Anokhin Institute of Normal Physiology, Academy of Medical Sciences of the USSR, Moscow. Laboratory of Pharmacology of the Nervous System, Institute of Pharmacology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR V. V. Zakusov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 88, No. 12, pp. 683–685, December, 1979.     

Effect of phospholipase A2 on development of pulmonary edema and on the pulmonary hemodynamics in intact and vagotomized animals

Laboratory of Pathophysiology of Respiration and Bioengineering Laboratory, Research Institute of General Pathology and Pathological Physiology, Academy of Medical Sciences of the USSR, Moscow. Department of Pathophysiology, Yaroslavl' Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR B. I. Tkachenko.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 110, No. 9, pp. 254–257 September, 1990.     

Comparative study of Ca,Mg-dependent endonuclease in cell nuclei by the use of monoclonal antibodies

Laboratory of Enzymes of Nucleic Acid Metabolism, Research Institute of Medical Enzymology, Academy of Medical Sciences of the USSR. Laboratory of Human Immunogenetics, Research Institute of Medical Genetics, Academy of Medical Sciences of the USSR, Moscow. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 105, No. 4, pp. 419–421, April, 1988.     

Immunogenesis and axoplasmatic transport in Wistar rats

Laboratory of Regulation of Immunopoiesis, Institute of Clinical Immunology, Siberian Branch, Academy of Medical Sciences of the USSR, Novosibirsk. Department of Biology, N. I. Pirogov Second Moscow Medical Institute, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR V. P. Lozova.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 112, No. 12, pp. 621–623, December, 1991.