尖端赛多孢子菌引起骨髓移植患者局部感染1例

由于尖端赛多孢子菌（Scedosporium apiospermum）培养和鉴定难度大,发现该菌引起的感染病例较少,本文报道了国内首例急性髓性白血病患者行自体骨髓移植后由尖端赛多孢子菌所致左侧腹股沟感染。     

羊毛状小孢子菌病199例

０年代以来,随着城市饲养动物者的逐渐增加,动物源性真菌病的感染率也明显增高,其中羊毛状小孢子菌病较为显著。现将我科１９９０～１９９７年门诊病人经过真菌镜检、培养,鉴定为羊毛状小孢子菌病１９９例报告如下。１临床资料本组中男１１２例,女８７例;年龄８个月...     

播散性球孢子菌病1例

球孢子菌病,又称峡谷热或"沙漠风湿",是一种地方流行病,主要流行于美国西南各洲及中美洲、南美洲部分地区.该病由人吸入球孢子菌引起肺部感染所致,严重者可播散,累及全身其他器官,即为播散性球孢子菌病,有一定致死性.普遍认为,球孢子菌系域外病原菌,流行区外病例主要考虑为输入性,我国球孢子菌病报道很少.     

播散型孢子丝菌病1例

<正>病人,男,19岁,战士。随部队野外驻训4个月回驻地后1个月,偶尔发现右手前臂出现一个黄豆大皮疹结节,随后右上臂也出现一个类似皮疹,同时右侧颜面部出现4个类似皮疹,有轻微瘙痒和疼痛感。皮疹逐渐增大,丘疹脓疱破溃后有黄色黏稠的脓性分泌物流出结痂,无明显压痛,在部队卫生所给予抗生素口服、消炎药膏外用等对症     

糠秕孢子菌性毛囊炎32例临床分析

目的总结糠秕孢子菌性毛囊炎诊断治疗经验。方法对32例糠秕孢子菌性毛囊炎发病的相关因素、临床表现、实验室检查、治疗方法进行分析评价。结果经6周治疗观察痊愈20例,显效8例,好转3例,无效1例,基本无不良反应。结论糠秕孢子菌性毛囊炎易被误诊、漏诊应提高警惕,治疗时应积极治疗原发病及祛除诱发因素,抗真菌药外用效果不明显时,宜同时口服。     

伏立康唑致睡眠后精神异常1例

1基本资料患者,女,70岁,抗．HCV阳性10余年,反复肝功异常1年,于2014年1月初出现发热,最高体温38．6℃,伴咳嗽、咯白色黏痰,经解放军309医院会诊除外肺结核,但仍予异烟肼、利福平等抗痨药物试验性治疗。     

糠秕孢子菌毛囊炎37例误诊分析

糠秕孢子菌毛囊炎是由圆形或卵圆形糠秕孢子菌引起的毛囊性皮肤真菌病，好发于中青年，其外观酷似寻常型痤疮、细菌性毛囊炎、毛囊虫样毛囊炎、脂溢性皮炎等皮肤病，临床上极易造成误诊。我科门诊自2002—04～2005—09共发现糠秕孢子菌毛囊炎误诊37例，其中24例为外院初诊，现就其误诊原因分析如下。     

犬小孢子菌致新生儿头癣3例

犬小孢子菌（microsporum canis）亦称羊毛状小孢子菌（microsporum lanosum sabouraud）是引起儿童头癣的主要病原菌,一般2～10岁儿童发病较多,婴儿感染较少见。笔者从3例新生儿患者头皮损中分离出犬小孢子菌,现报告如下。 例1,男,27d。出生2周左侧头顶部出现一黄豆大结节,逐渐扩展为黄色油腻脱屑性斑块。于2009—11—05到本院第一次就诊,皮肤科检查：患儿头顶部有1片4cm×5cm斑块,基底微红,表面覆大量黄色油脂性污痂,边缘隆起,界限清楚。皮损处头发稀少,松动易折断。     

AIDS伴发肺孢子菌肺炎的CT征象(附12例报告)

目的分析获得性免疫缺陷综合征(AIDS)合并肺孢子菌肺炎(PCP)的CT征象,并评价多层螺旋CT的诊断价值。方法 12例(8例男性,4例女性;年龄30～63岁,平均43岁)由临床证实的AIDS合并PCP患者均经16层螺旋CT胸部平扫。对所有患者的主要CT表现及其伴发征象进行了回顾性分析。结果 CT扫描证实,所有患者均表现两肺内呈地图样分布的磨玻璃样影或云雾状高密度影。同时,伴发的其他CT征象包括网格状影和小叶间隔增厚(6例),小肺气囊肿(5例),斑片状影(4例),胸膜下陷(3例)以及局限性胸膜增厚(2例),但未见胸腔积液、心包积液及淋巴结肿大。结论出现于两肺内呈地图样分布的磨玻璃样影及云雾状高密度影,同时伴有斑片状及网格状影、肺气囊肿以及小叶间隔增厚,符合PCP以肺间质浸润为主的CT表现,因此,多层螺旋CT是诊断AIDS合并PCP的一种有效方法,并对指导临床治疗和筛查AIDS患者具有实用意义。     

兰州地区犬小孢子菌感染情况及药敏试验研究

犬小孢子菌(M icrosporum can is bod in)为发外型亲动物型皮肤癣菌。胡沙沙[1]综合分析了国外学者的研究结果,发现犬小孢子菌所致的皮肤癣菌病发病率位于世界浅部真菌病的前四位。本研究调查了兰州地区犬小孢子菌的感染情况,并参考M-38A方案测定了犬小孢子菌对5种常用抗真菌药物的敏感性。1对象和方法1.1对象:对2007-07~12在兰州大学第二医院皮肤科被拟诊为真菌感染的患者进行临床标本的取样、镜检、培养、鉴定,留取犬小孢子菌样本共55例。标本来源:患者中男性40例(72.72%),女性15例(27.27%);年龄1~47岁,平均(9.1±2.44)岁;头癣47例(85.45%),其中白癣45例(81.81%),脓癣2例(3.64%);体癣者8例(14.55%);49例(89.09%)有2周到1年半不等的动物接触史。1.2药敏材料和质控菌株:RPM I-1640液体培养基,购自上海生工。灰黄霉素、氟康唑、伊曲康唑及氟康唑购自上海科恒公司,特比萘芬购自西安大唐药业公司。所有药物均以原料粉形式提供。质控菌株为近平滑念珠菌ATCC-22019,由北京大学真菌与真菌病研究中心惠赠。1.3抗真菌药物...     

Petriellidium boydii infection of the knee: A case report

A case of Petriellidium boydii (synonym: Allescheria boydii) infection of the knee joint is described. It followed a penetrating soft tissue injury with a pitchfork. Such infections are rare in this country and bone involvement has not been recorded previously except in maduramycosis contracted in tropical areas.     

Arterial injury during revision total knee replacement A case report

A case of an anatomical variation of the arterial vessels in the popliteal fossa, leading to a vascular transection during a total knee revision is presented. The authors believe this complication should be considered in all cases of knee revision surgery.     

膝关节创伤后骨挫伤1例报告

19岁男性患者,膝关节伤后疼痛2h就诊,X线示骨质无异常,按软组织伤处理。1周后无缓解再次就诊,行MRI检查,于胫骨上端内侧可见T1WI低信号影和短时反转恢复序列(STIR序列)高信号影,按骨挫伤诊治。     

Brucella melitensis infection in total knee arthroplasty: a case report

We report a case of a 63-year-old female patient who underwent a total knee arthroplasty in which the knee later became infected with Brucella melitensis. Diagnosis was made by positive culture of a sinus tract discharge. Radiological views of the knee did not show signs of implant loosening. The patient was successfully treated with rifampicin and doxycycline without surgery.     

Pre and retroperitoneal necrotizing fasciitis after COVID-19 infection: A case report

Necrotizing fasciitis is a serious infection that originates in the subcutaneous tissues. We present a case of 52 years old male patient who developed preperitoneal and retroperitoneal necrotizing fasciitis 2 weeks after the start of Coronavirus-19 infection. Preoperative abdominal computed tomography with intravenous and oral contrast revealed pre and retroperitoneal spread of air loculi with turbid fluid patches within necrotic tissues. After surgical excision of the lesion, histopathological and microbiological examinations of the samples revealed necrotizing fasciitis. This is the first report of preperitoneal and retroperitoneal necrotizing fasciitis after Coronavirus-19 infection in 52 years old male with no history of trauma or immunocompromised condition. Coronavirus-19 infection may increase the liability of patients to develop overwhelming infection and it may also delay the patient presentation causing serious health-related emergencies. The findings of necrotizing fasciitis on clinical grounds or imaging studies can help in diagnosis as well as the surgical intervention and appropriate antibiotics can highly impact the prognosis and survival of the patient.     

A rare cause for knee pain: fracture of the femoral component after TKR. A case report

We report the rare case of sudden knee pain due to fracture of the total knee replacement nine years after implantation. Fracture occured because of subsequent osteolysis due to polyethylene wear.     

左侧腹股沟股疝手术后股神经损伤1例分析

左侧腹股沟股疝患者1例,行手术后出现左下肢感觉、功能异常,术后3个月转上级医院治疗,手术探查,明确为左侧腹股沟区股神经损伤(受压)。     

腹部钝性伤致十二指肠壁内血肿影像学诊断1例

本文报道1例腹部钝性伤致十二指肠壁内血肿的影像学诊断体会.患者因上腹部撞击致伤,伤后以腹痛伴恶心呕吐为主.作者结合文献讨论了本例十二指肠壁内血肿影像学确定诊断并治疗成功的经验及体会.