Médicaments et performance de la fonction d'équilibration

Introduction – Balance control in some sports discipline can be the aim of the action, and its breaking off can expose to severe trauma.Synthesis of facts – Some drugs' adverse effects can induce lower equilibrium performance, in relation for example with vigilance drop or vestibular ototoxicity. The drug effect site can concern one or more links in the chain (peripheral or central impact). Individual sensitivity is variable, as well as speed of reversibility.Conclusion – Symptoms induced by pathology for which therapy is prescribed are sometimes difficult to distinguish from those induced by therapy itself.     

Une nouvelle méthode de lecture de la réaction précipitante en Médecine Légale

Sans résuméVortrag, gelegentlich der Tagung der Deutschen Gesellschaft für gerichtliche und soziale Medizin in München 1952.     

Corrélations entre scores au questionnaire de la Société française de médecine du sport et concentrations de cortisol et testostérone salivaires lors du suivi d’une équipe de rugby de haut niveau

Objective. – To carry out the follow-up of 21 high level rugby players by means of the psycho-comportmental questionnaire of the “French Society of Sports Medicine” (SFMS), of the salivary testosterone (T) and cortisol (C) levels and of their ratio T/C during the sporting season.Materials and methods. – The players provided three samples of saliva, at awakening (8 am), just before the lunch (11 am), and at 17 pm in order to assay cortisol and testosterone. The first measurements were done at the beginning of season (T1), 12 weeks (T2) and 24 weeks (T3) after T1. At the same periods, they completed the 54 items of the SFMS questionnaire which allows to give a score (from 1 to 54) proportional to the state of tiredness of the subject. The performance of the team was estimated from the ratio of victories to the number of matches played over the season.Results and discussion. – The increase in the score obtained with the SFMS questionnaire and the variations of the hormonal levels during the season seem to reflect a normal adaptation phenomenon to the training load, a fact which is confirmed by the maintenance of the same level of performance of the team throughout the season. This study permitted to highlight the parallel evolutions between the psycho-comportemental index (score) and the hormonal markers of the state of tiredness. Thus, it appears that the SFMS questionnaire is an interesting and easy to employ tool to evaluate the state of tiredness (or reciprocally of form) of a sportsman during the course of the sporting season.     

Les bases génétiques et moléculaires de la performance et de l'adaptation à l'exercice physique

Objectives – This paper reviews the state of our knowledge on the genetic and molecular bases of performance and the response to exercise training, the theme of the inaugural conference of the XIXth annual meeting of the Société Française de Médecine du Sport held in Rennes in October 1999.Topics – The studies on the genetic bases of performance performed over the past 20 years suggest that 25 to 50% of interindividual differences observed in maximal and sub-maximal oxygen consumption as well as in other indicators of aerobic performance could be explained by genetic factors. For metabolic and histochemical properties of skeletal muscle, heritabilities ranging from 40 to 70% have been reported. Considerable interindividual differences are also observed in the cardiorespiratory, metabolic and morphologic adaptations to exercise training and results from twin and family studies suggest that these differences are also determined by genetic factors. Unlike many other complex traits such as hypertension or obesity, the search for candidate genes of performance is in its infancy. Only a few studies with candidate genes such as the angiotensin converting enzyme (ACE), the muscle specific creatine kinase (CKMM) or genes of mitochondrial DNA have reported positive results with indicators of aerobic performance.Conclusion – More studies are needed before any conclusion could be made about the role of these genes in performance and adaptation to exercise training. Although the molecular dissection of performance and adaptation to regular exercise is a complex task, considerable progress will probably be achieved in the next decade in our understanding of the molecular basis of these complex phenotypes.     

Cinétique du cortisol et de l'hormone de croissance plasmatiques lors de deux épreuves sous-maximales avec et sans récupération

Introduction – The purpose of this study is to evaluate cortisol and growth hormone kinetics in plasma during a sub-maximal exercise with and without recovery.Results – There is a significant difference of cortisol and growth hormone kinetics between the two tests. The cortisol concentration increased significantly during exercise without recovery period, the changes of plasmatic cortisol were not significant during exercise with recovery. Plasmatic growth hormone increases after exercise without recovery.Conclusion – The absence of recovery period contributes to increase considerably the level of cortisol and growth hormone in plasma and decreases probably anabolic process in post exercise period.