中枢神经细胞瘤7例报告

目的　报道 7例中枢神经细胞瘤 ,探讨中枢神经细胞瘤的临床特点及治疗方法。方法　结合文献回顾性分析 7例颅内中枢神经细胞瘤临床特征。结果　 7例肿瘤均获全切除 ,无特殊并发症 ,无手术死亡。术后均行放疗。结论　中枢神经细胞瘤手术结合放疗为最佳治疗方法 ,预后良好     

复合型食管癌一例报告

1、病例报告。患者男，68岁，因进行性吞咽困难半个月来我院就诊，院外食管钡餐检查提示，食管中段癌，我院食管钡餐检查提示，食管平T1-T2平面可见菜花状充盈缺损，管腔扩张，钡剂通过明显受阻，该处管壁僵硬，黏膜破坏，病变长约11cm，贲门未见异常。     

肾恶性纤维组织细胞瘤误诊1例报告

1资料 患者男性,49岁,主诉腰疼1个月,在当地B超怀疑"双肾肿物"于2003年1月10日收入院.患者自发病以来无发热,血尿等.入院查体:双肾区无异常隆起,右肾区轻度压痛.影像学检查:B超所见右肾外侧中部一低回声实性占位,大小约3.9cm×3.9cm×3.8cm,边界不整齐,内部回声不均;左肾下极一囊实性肿物,回声不均,大小4.1cm×2.9cm×2.8cm.拟诊双肾癌.     

肺透明细胞瘤一例报告

1病例报告 患者女,35岁。2006年8月1日体检发现有肺肿块,于2006年9月14日住入上海交通大学附属瑞金医院。患者入院前无发热、咳嗽或胸痛等症状,入院后查体无阳性体征。CT检查表现为右肺中叶圆形肿块,直径2.0cm,边缘光整,无毛刺。术前诊断右肺中叶占位,良性肿瘤可能。     

成人肝母细胞瘤二例报告

1病例报告 例1,患者男,72岁.因进食后上腹疼痛不适6个月余入院.手术所见:肿瘤位于肝左外叶,8 cm×6 cm大小,包膜完整,遂行肝左外叶切除.病理检查:大体标本为部分肝组织体积14 cm×11 cm × 6 cm,切面见肿物,直径9 cm,灰黄色,分叶状,与周围界限清.镜下:瘤细胞由不成熟的肝细胞组成,圆形,胞浆丰富,嗜酸,瘤细胞呈条带状、巢状、菊形团状,细胞之间可见髓外造血.病理诊断:肝母细胞瘤(上皮型).     

肺癌肉瘤二例报告

1病例报告例1，患者女，38岁，咳嗽半年，痰中带血3个月，胸部CT显示左肺中心型占位，直径5cm，表面短毛刺状，并左上肺不张。1998年6月8日入院，诊断为肺癌。在全麻下行左全肺切除、肺门淋巴结清除。术后病理为肺腺癌混合纤维肉瘤，肺门、隆突下、纵隔淋巴结腺癌转移4／4、3／3、1／4。术后给顺铂 依托泊苷方案化疗4个疗程。术后8个月死于脑转移。     

胃“一点癌”：附四例报告

胃“一点癌”（附四例报告）上海长宁区红十字一心医院张国维，蒋志泽，陈昌谷胃“一点癌”非常罕见，我们收集４例，胃低张双对比造影诊断均为胃炎，内窥镜活检找到典型癌细胞，经手术标本病理检查证实无癌细胞残留，现报告分析如下。病例报告例１．女，５７岁。二周来感...     

胃不典型类癌一例报告

1病例报告 患者男,65岁。因上腹部不适1个月伴恶心呕吐入院。体检：上腹部压痛。胃镜示：胃窦部小弯侧见溃疡型肿物,边缘隆起,如火山口状,溃疡底见坏死物。B超发现肝转移瘤。手术所见：瘤体位于胃窦小弯侧,溃疡型,面积8.0 cm×7.0 cm,胃周淋巴结肿大。行胃大部切除术。病理检查：小弯侧见溃疡型肿物,面积6.0     

中枢神经细胞瘤1 7例临床分析

目的：报道17例中枢神经细胞瘤，结合文献讨论并总结神经细胞瘤的临床特点和治疗方法。方法：回顾性分析1997年1月至2000年10月17例神经细胞瘤，并复习文献。结果：17例肿瘤14例全切除，3例近全切除，死亡1例。术后均行放射治疗。结论：中枢神经细胞瘤手术结合放疗为最佳治疗方法，预后良好。     

Linear Accelerator Radiosurgery for Central Neurocytoma: A Case Report

This study presents a case of central neurocytoma successfully treated with linear accelerator (LINAC) stereotactic radiosurgery. Originally, the tumor in the left lateral ventricle was removed by craniotomy, but a small residual mass was detected in follow-up magnetic resonance imagery 6 months after the operation. A further 6 months later, additional radiographic studies revealed that the residual mass had grown. LINAC radiosurgery was then performed, in which 1750cGy doses were delivered at the 70% level with 3 isocenters (collimator size, 2cm). The mass was completely absent over the duration of follow-up, including the final MR imagery examination 51 months after radiosurgery. LINAC radiosurgery is suggested to be a good treatment modality for residual or recurrent central neurocytoma.     

Central Neurocytoma: A Review

Central neurocytomas are rare intraventricular neoplasms of the central nervous system, compromising 0.25-0.5% of brain tumors. The diagnosis and management of these tumors remains controversial since most clinical series are small. Typically, patients with central neurocytomas have a favorable prognosis, but in some cases the clinical course is more aggressive. Although histological features of anaplasia do not predict biologic behavior, proliferation markers including MIB-1 might be more useful in predicting relapse. The most important therapeutic modality is surgery, and a safe maximal resection confers the best long-term outcome. In cases of a subtotal resection,'standard external beam radiation can be added or radiation can be delayed until tumor progression occurs. Smaller residual tumor volumes or recurrences can be treated with more conformal radiation or focused radiosurgery. Re-operation for recurrence should be considered if the procedure can be safely performed. Chemotherapy may be useful for recurrent central neurocytomas that cannot be resected and have been radiated, although long-term responses have not been reported for chemotherapy. Overall, this paper reviews the findings of the larger studies and highlights some of the important case reports that contribute to the current management of central neurocytomas.     

Endobronchial Lipoma: A Report of Three Cases

Although lipomas are common benign neoplasms of soft tissue,endobronchial lipoma is rare. We have treated three patientswith endobronchial lipoma over the five years. In two of themlesions were located in segmental or subsegmental bronchi andproduced no symptoms. There are very few such cases reportedin the English medical literature. In the first case, pneumonectomywas performed because of destruction of the lung due to recurrentpneumonia. The second case had no symptoms and the tumor waslocated at the bifurcation of right B⁴a and B⁴b. A right middlelobectomy was performed, because the distal end of the tumorcould not be visualized by fiberoptic brorichoscopy. In thethird case, which was a case of lung cancer, an endobronchiallipoma was found during fiberoptic bronchoscopy, and was completelyremoved endoscopically. Due to their benign nature, endobronchiallipomas should be initially treated with endoscopic surgeryor endoscopic laser vaporization. Nevertheless, if the tumoris large and dumbbell-shaped on tomography or CT, endoscopicprocedures are not appropriate. Furthermore, if destructivepulmonary change due to the tumor is severe, the remaining peripherallung will not recover after endoscopic procedures, even if theyare removed successfully. When the biopsy specimen is too smallto allow evaluation of the whole tumor, surgical resection shouldalso be considered for definitive diagnosis.     

Central Neurocytoma with Craniospinal Dissemination

Central neurocytoma was first described by Hassoun et al. in 1982. The tumor is a rare benign tumor of the central nervous system, usually located in the lateral ventricles. Most reported cases are histologically and clinically benign. Several cases with recurrence have been described. Including the case presented here, only seven cases with craniospinal dissemination have been reported. None of the previous cases with dissemination had histological atypia but most did have a high MIB-1 labeling index (MIB-1 LI). Our patient had a high MIB-1 LI (4.6%) and dissemination was found to have advanced through the anterior horns of the lateral ventricles and to the spinal cord at the T4 level. The patient underwent partial resection of the tumor with follow-up radiation treatments for the residual tumor and dissemination. After the radiation, the size of the tumor decreased. The report of this case will be helpful in the treatment of disseminated central neurocytoma.     

原发中枢神经系统淋巴瘤17例临床分析

目的:原发性中枢神经系统淋巴瘤(PCNSL)是一种较少见的中枢神经系统恶性肿瘤.近年发病率有逐年增高的趋势,本文探讨其临床特点、诊治方案及临床疗效.方法:总结1999年9月～2007年12月收治的17例患者(男性8例,女性9例,年龄19～80岁),均经病理证实为B细胞来源非霍奇金淋巴瘤.全部患者接受放疗,其中15例放疗后接受化疗等综合治疗.结合文献对原发性中枢神经系统淋巴瘤患者的临床特点、病理学检查、影像学表现、治疗及预后进行回顾性分析.结果:本病以中老年人多见,发病急,病程短,病情进展快.临床表现复杂,颅内高压为主要临床表现之一.头颅CT以及MRI检查显示中枢侵及额叶多见,CT扫描多表现为较高密度肿块,MRI显示T1加权像多呈低信号,T2加权像多呈高信号.CT和MRI增强扫描病灶多呈均匀明显强化,可单发或多发,极少发生出血、钙化或囊变.PCNSL主要起源于B细胞,包括手术、放疗、化疗和免疫治疗的综合治疗效果较好.17例患者随访7～65个月,中位时间17个月,平均生存23.9个月.1、3年生存率分别为76.5%和23.5%,5年生存率仅有5.9%.结论:PCNSL是一组异质性肿瘤,侵袭性强,预后差,伴脊髓侵犯者则预后更差.其临床、影像学表现复杂多变,无特异性,术前诊断困难.确诊主要依靠病理检查,三维立体定向穿刺活检(定向活检)可显著提高诊断效率.其病程短,疗效不理想,最佳治疗方案是手术加放疗、化疗的联合治疗.虽然对放射及化学药物治疗敏感,但缺乏共识方案,较全身及其他部位淋巴瘤预后差.中等剂量放疗加足疗程化疗是有效的治疗方法,增加放射剂量未能改善肿瘤控制.综合治疗是提高本病疗效的关键.     

Melanoma Metastatic to Central Neurocytoma: A Novel Case of Tumor-to-tumor Metastasis

We report a case of a 43-Year-old man with known metastatic melanoma and two intracranial tumors, one of which was resected and confirmed to be melanoma. At autopsy, the second lesion was found to be a central neurocytoma harboring metastatic melanoma. To our knowledge, this represents the first reported case of tumor-to-tumor metastasis to a central neurocytoma. The most common pattern of tumor-to-tumor metastasis for intracranial neoplasms, in which an aggressive high-grade malignancy serves as the source tumor and a more indolent neoplasm serves as the recipient tumor, is affirmed by the present novel example.     

双胞胎肝母细胞瘤3例报告并文献复习

  目的  分析肝母细胞瘤的家族遗传倾向, 为临床遗传咨询及早诊断、早治疗提供依据。  方法  收集中国医科大学附属盛京医院2005年6月至2011年11月间收治的3例双胞胎肝母细胞瘤患儿的资料, 结合患儿生化、影像、治疗方案、生存期、家族史及相关文献报道分析遗传相关因素。  结果  本文中3例双胞胎患儿均为单发, 无家族史, 其中1例为早产儿。3例患儿均采用手术治疗, 经病理证实为肝母细胞瘤, 术后1例患儿因失血性休克死亡, 余2例采用不同的化疗方案, 均获得完全缓解。自1969年至今, 已有8例关于兄弟姐妹同患此病的文献报道。8组文献中5组患儿家族中有肿瘤(多数为结肠癌)及家族性结肠息肉病史, 其中3组还有基因异常改变。  结论  肝母细胞瘤是一种罕见的小儿肝脏恶性肿瘤, 具有家族遗传倾向, 与结肠癌及家族性结肠息肉综合征密不可分, 在诊疗过程中, 有必要加强家属的认知, 做好预防保健, 争取早发现早诊断早治疗。      

妊娠合并卵巢癌3例报告

妊娠合并肿瘤颇为常见 ,尤以合并子宫肌瘤和卵巢成熟畸胎瘤较多 ,但合并卵巢癌者极为罕见。由于恶性肿瘤的死亡率极高 ,当其合并妊娠时多因妊娠而忽略或妨碍对恶性肿瘤的及时诊治从而导致不良后果。本院自１９９４年以来共收治妊娠合并卵巢癌３例 ,现报道如下。例１ ,１８岁 ,因停经６个月多 ,右腰酸痛３天于１９９４年１２月１３日入院。查体 :神清、痛苦貌、心肺（ -） ,宫底脐上二指 ,宫底右上方可及拳头大小肿块伴有压痛 ,双肾区无叩痛 ,Ｂ超示宫内活胎 ,右髂嵴上方平脐处探及６．７ｃｍ×５．３ｃｍ×３．６ｃｍ低回声团块 ,有包膜 ,境…