23G微创玻璃体切割术在孔源性视网膜脱离中的应用

目的：评估23G经结膜无缝线玻璃体切割手术治疗孔源性视网膜脱离的安全性及有效性。 方法：前瞻性选择2010-03/2011-06共26例26眼不伴有严重增生性病变的孔源性视网膜脱离病历,均行23G切割手术。记录术前、术后的最佳矫正视力（BCVA）、眼压,术中及术后并发症。 结果：一次性复位视网膜21例（81%）,最终复位视网膜25例（96%）。术后3mo最佳矫正视力较术前提高21例（80%）,不变3例（12%）,下降2例（8%）。术后1d眼压较术前下降,此差异有统计学意义（P<0.01）。低眼压（≤6mmHg）2例,持续2wk,但未发生脉络膜脱离。 结论：23G手术治疗孔源性视网膜脱离解剖复位率满意,术后视力改善明显。但23G微创手术的优势并没有在孔源性视网膜脱离的手术中得到充分体现,反而要面临更高的手术失败的风险。     

Primary 23-gauge sutureless vitrectomy for rhegmatogenous retinal detachment

Aims:

To report a prospective non-comparative consecutive interventional study on the safety and efficacy of 23-Gauge transconjunctival sutureless pars plana vitrectomy for primary rhegmatogenous retinal detachment (RRD).

Materials and Methods:

Fifty eyes of 50 consecutive patients were recruited between June 2007 and January 2008. All surgeries were performed using the one-step 23-Gauge system with angled incisions. The surgical protocol consisted of a minimum of eight clinical visits: baseline, 1 day, 1 week, 1-, 3- and 6- months after the initial surgery. The endpoints were anatomical, functional results and complications arising from the surgery.

Results:

Anatomical success was achieved in 82% of cases (41 out of 50) with single surgery and rose to 98% (49 out of 50) with additional surgery. Mean visual acuity improved from logMAR 0.48(SD 0.36) to 0.26(SD 0.31), P < 0.001. Two cases with ocular hypotony, defined as an intraocular pressure ≤ 6mmHg, that were associated with a choroidal detachment were seen.

Conclusions:

Acceptable anatomical and functional success rates can be achieved with primary 23-Gauge transconjunctival sutureless vitrectomy for RRD. We found that the approach technique is different from conventional vitrectomy and the complications arising from post surgical hypotony and leakage from sclerotomies are potentially higher compared to 20-Gauge vitrectomy.     

23G玻璃体视网膜手术治疗孔源性视网膜脱离

目的：报告23G玻璃体视网膜手术治疗孔源性视网膜脱离（rhegmatogenous retinal detachment,RRD）的有效性和安全性。 方法：本回顾性研究中,49例49眼RRD患者于2007-01/2009-07在我院行23G经巩膜无缝线玻璃体切除术纳入研究。 结果：平均随访时间8.9±7.7mo(1~28mo)。47眼(95.9%)视网膜再次脱离经一次手术治愈,2眼因新出现裂孔的视网膜再次脱离通过23G经巩膜无缝线玻璃体切除术治愈。术前平均logMAR视力2.01±0.47,术后1.3±0.5(P<0.001, Paired t-test)。术前平均眼压（intraocular pressure,IOP）14.1±2.8mmHg,术后1d平均眼压12.3±3.6mmHg,术后1wk平均眼压13.1±2.1mmHg,术后1mo平均眼压14.3±2.2mmHg。术中医源性周边视网膜裂孔1眼(2.0%)。巩膜或结膜切口不要求缝合,无1眼需要转换为20G玻璃体切除术。 结论：23G经巩膜无缝线玻璃体切除术可以有效,安全的治疗RRD。     

Primary 23-gauge vitreoretinal surgery for rhegmatogenous retinal detachment

AIM: To report the effectiveness and safety of primary 23-Gauge (G) vitreoretinal surgery for rhegmatogenous retinal detachment (RRD). METHODS: In this retrospective study, 49 eyes of 49 consecutive patients who underwent primary 23-G transconjunctival sutureless vitrectomy (TSV) for RRD between January 2007 and July 2009 at our institution were evaluated. RESULTS: Mean follow-up time was 8.9±7.7 months (1-28 months). Retinal reattachment was achieved with a single operation in 47(95.9%) of 49 eyes. In two eyes (4.1%), retinal redetachment due to new breaks was successfully treated with reoperation using the 23-G TSV system. Mean logMAR visual acuity was 2.01±0.47 preoperatively and 1.3±0.5 postoperatively (P<0.001, Paired t-test). Mean preoperative intraocular pressure (IOP) was 14.1±2.8mmHg. Mean postoperative IOP was 12.3±3.6mmHg at 1 day, 13.1±2.1mmHg at 1 week, 14.3±2.2mmHg at 1 month. Iatrogenic peripheral retinal break was observed in 1 eye (2.0%) intraoperatively. No sutures were required to close the scleral or conjunctival openings, and no eyes required convertion of surgery to 20-G vitrectomy. CONCLUSION: Primary 23-G TSV system was observed to be effective and safe in the treatment of RRD.     

23G高速玻璃体切除手术治疗孔源性视网膜脱离的初步临床观察

目的:探讨23G高速玻璃体切除手术治疗孔源性视网膜脱离的临床效果。方法:前瞻性选择2009-03/2009-10一组合并较明显玻璃体混浊、玻璃体视网膜粘连牵拉或合并玻璃体积血的孔源性视网膜脱离病例共20例20眼,应用23G玻璃体切除手术联合膨胀气体全氟丙烷(C3F8)填充。统计分析视网膜解剖复位率、术后3mo时最佳矫正视力、术中、术后并发症、手术时间及术后眼部刺激征的严重程度,术后平均随访6mo。结果:所有20眼均一次手术后视网膜完全复位。未发生器械损伤晶状体或医源性视网膜裂孔等术中并发症。15眼黄斑已脱离眼的术前最佳矫正视力为0.02～0.5(log-MAR视力为0.3～2.0,平均1.187±0.616),术后3mo时最佳矫正视力为0.3～0.8(logMAR视力为0.1～0.52,平均0.276±0.114),差异具有统计学意义(t=5.756,P<0.01);5眼黄斑未脱离眼的术前最佳矫正视力为0.8～1.0(logMAR视力为0～0.52,平均0.218±0.276),术后3mo时最佳矫正视力为0.6～1.0(logMAR视力为0～0.52,平均0.312±0.285),差异没有统计学意义(t=-1.0,P=0.374)。手术后未发生低眼压、脉络膜脱离或眼内炎等切口相关并发症,无增生性玻璃体视网膜病变(PVR)发生。3眼术后第1d出现轻度晶状体后囊下羽毛状混浊,1wk内消退。至随访结束时,4眼(20%)晶状体核密度增加,其余病例无新生白内障或原白内障明显加重。5眼(25%)术后一过性眼压升高,眼压均<30mmHg,经局部使用1～2种降眼压滴眼液,3d内恢复正常,平均术后第7d眼压为14.6±3.4mmHg。结论:23G玻璃体切除手术治疗孔源性视网膜脱离安全有效,缝合手术切口可避免并发症,是值得推广的技术。     

23G玻璃体切除术治疗孔源性视网膜脱离

目的观察23G玻璃体切除手术治疗孔源性视网膜脱离的临床效果。方法对23例（23眼）孔源性视网膜脱离应用23G玻璃体切除手术联合全氟丙烷（C3F8）或硅油填充,下方视网膜裂孔者联合巩膜外加压,合并白内障者同时对白内障行超声乳化吸出术。随访3～10个月,观察术后视网膜复位、视力等情况。结果23眼手术顺利完成。术后3个月时视网膜复位21眼（91．30％）,2眼（8．70％）视网膜脱离复发,再次玻璃体手术填充硅油视网膜复位。未发生其他并发症。术后3个月时视力：（1）黄斑区未脱离眼：术前最佳矫正视力0．1～0．5,LogMAR视力：1．0～0．3,平均0．42±0．29。术后最佳矫正视力0．2—0．5,LogMAR视力：0．7～0．3,平均0．38±0．19,t=1．83,P〉0．05,与术前比较差异无统计学意义。（2）黄斑区脱离眼：术前最佳矫正视力0．08～0．2,LogMAR视力：1．1～0．7,平均0．81±0．13。术后最佳矫正视力0．15—0．5,LogMAR视力：0．8～0．3,平均0．47-e0．26,t=5．78,P〈0．05,与术前比较差异有统计学意义。结论23G玻璃体切除手术治疗孔源性视网膜脱离效果良好,并发症少。     

玻璃体切割术治疗孔源性视网膜脱离伴玻璃体积血的临床研究

目的:探讨孔源性视网膜脱离伴玻璃体积血的发病原因、临床特征和玻璃体切割术的治疗效果。方法:回顾分析24例24眼因孔源性视网膜脱离伴玻璃体积血接受玻璃体切割手术治疗患者的临床资料。结果:年龄<45岁的青年组共11例;年龄45～59岁的中年组共9例;年龄>60的老年组4例。21例为马蹄形裂孔,其中马蹄形裂孔<1PD者2例,1PD～<2PD者14例,2PD～<1象限者5例;圆形裂孔者3例,均<1PD。裂孔位于视网膜颞上方者13例,颞下方者8例,鼻上方者3例;视网膜脱离范围:颞上方者10例,鼻上者2例,全脱者1例,下方者11例。病程和术后视力:1mo组16例,视力0.2～0.4者13例,≥0.5者3例;2mo组5例,视力0.01～0.1者3例,0.2～0.4者2例;3mo组1例,视力0.01～0.1;>3mo组2例,视力手动1例,数指1例。结论:孔源性视网膜脱离伴玻璃体积血尽早明确诊断并及时行玻璃体切割手术能够取得较好疗效。     

Epiretinal membrane following pars plana vitrectomy for rhegmatogenous retinal detachment repair

AIM: To determine the rate and possible contributors for post-pars plana vitrectomy (PPV) epiretinal membrane (ERM) in patients treated for rhegmatogenous retinal detachment (RRD). METHODS: This prospective, nonrandomized study comprised 47 consecutive patients (47 eyes) with acute RRD treated with 23 G post-PPV. All participants were followed prospectively for 6mo for the development of ERM using spectral domain optical coherence tomography. Preoperative and intraoperative data were collected by questionnaires to surgeons. Main outcome measure was the percentage of the ERM formation following post-PPV for RRD. RESULTS: ERM developed postoperatively in 23 eyes (48.9%), none necessitated surgical removal. There was a statistically significant difference between patients with and without ERM postoperatively in preoperative best corrected visual acuity (median logMAR 1.9 vs 0.3, respectively; P=0.003) rate of macula-off (69.6% vs 37.5%, respectively, P=0.028), and rate of ≥5 cryo-applications (55.6% and 18.8%, respectively, P=0.039). ERM developed mainly between the 1st and 3rd months of follow-up. Macula-off status increased the risk of ERM, with the odds ratio of 3.81 (P=0.031). CONCLUSION: ERM is a frequent post RRD finding, and its development is associated with macula-off RRD.     

23 G微创玻璃体手术联合吊顶灯照明系统治疗复杂性外伤性视网膜脱离

目的 观察23 G玻璃体切割手术联合吊顶灯治疗复杂性外伤性视网膜脱离的临床疗效及并发症情况.方法 回顾性分析2012年6月至2013年12月在我院眼科中心住院的50例(50眼)复杂性外伤性视网膜脱离患者,行吊顶灯辅助下23 G玻璃体切割手术,随访2～6个月,平均3.6个月,观察所有患者术前和术后不同时间点最佳矫正视力、眼压变化情况,分析术中、术后并发症,分析视网膜解剖复位率等情况.结果 术中无医源性裂孔、出血等并发症发生,术后无脉络膜脱离、眼内炎等并发症发生.10眼(20.0％)出现术后高眼压,经治疗后均恢复正常.术毕拔除套管后巩膜切口渗漏需缝合者15眼(30.0％).最终视网膜全部复位.术后1周及1个月、3个月测得的平均眼压与术前相比差异均无统计学意义(均为P＞0.05).术后1个月、3个月最佳矫正视力均较术前提高,差异均有统计学意义(均为P＜0.05).结论 23 G玻璃体切割术具有微创、手术时间短等优点,联合吊顶灯治疗复杂性外伤性视网膜脱离是一种安全有效的手术方法.     

The incidence and distribution of iatrogenic retinal tears in 20-gauge and 23-gauge vitrectomy

Purpose

The development of 23-gauge vitrectomy surgery has many benefits including a reduction in surgical time and faster postoperative rehabilitation; however, some have suggested that the complication rate is higher. To assess this we compared the incidence and distribution of iatrogenic retinal tears in 20- and 23-gauge surgery.

Methods

Fifty consecutive 23-gauge and 50 consecutive 20-gauge vitrectomy cases were selected; eyes with a history of previous vitreoretinal surgery were excluded. All surgery was performed by two surgeons (JL and RN). Entry-site breaks (ESB) were defined as any new vitreoretinal abnormality occurring within 1 clock hour of an entry site for which treatment with cryotherapy was deemed necessary. Data were collected by retrospective case note review. Statistical analysis was carried out using Fisher''s exact and χ²-tests.

Results

ESB occurred in 24% (12/50) of cases in the 20-gauge group compared with 8% (4/50) in the 23-gauge group (P=0.03); 88% (14/16) occurred superiorly on the same side as the surgeons'' dominant hand. Iatrogenic breaks recorded elsewhere indicated an increased incidence in the 20-gauge group (9/50 compared with 6/50 in 23-gauge) but this did not achieve significance; the most common position was at 6 o''clock.

Conclusions

23-Gauge vitrectomy is associated with significantly fewer ESB when compared with conventional 20-gauge vitrectomy. The incidence of other iatrogenic breaks did not appear to be significantly different between the two groups.     

孔源性视网膜脱离235例临床分析

目的:探讨孔源性视网膜脱离(rhegmatogenous retinal de-tachment,RRD)的疾病特征、手术疗效及治愈关键。方法:对近两年间我院收治的235例(240眼)RRD病例做回顾性分析。结果:30岁以上患者168例占71.5%、其中合并高血压31例占18.5%,高度近视89眼占37.1%。临床脱离时间平均49d,裂孔中圆孔占43.0%,分布于颞上象限占46.6%。一次手术成功率91.3%,总治愈率达93.8%。结论:本地区RRD主要特征:好发于中老年患者、与高度近视密切相关、临床脱离时间长、合并高血压比例高。裂孔以圆孔为主,颞上象限分布居多。目前手术治疗仍是治疗RRD最有效的方法。对于复杂及复发的病例应首选玻璃体切割治疗。     

Changes in axial length after vitrectomy for rhegmatogenous retinal detachment combined with choroidal detachment

AIM: To report the postoperative axial length (AL) changes in rhegmatogenous retinal detachment combined with choroidal detachment (RRD-CD) patients. METHODS: The medical records of 97 consecutive patients from January 2015 to December 2018 were reviewed. Patients included were divided into RRD-CD and RRD only groups. All patients had received AL measurements before pars plana vitrectomy (PPV) and before silicone oil removal (SOR). The changes in AL of the two groups were compared. In addition, the potential factors related to AL changes were analyzed. RESULTS: AL elongation after PPV was 1.01 mm [interquartile range (IQR): 0.37, 1.79; P=0.02] in the RRD-CD group, which was greater than in RRD only group (0.15 mm, IQR: 0.04, 0.41; P<0.001). AL increased 0.06 mm per 1 mm Hg intraocular pressure changes in the RRD-CD group (R2=0.11, P=0.03). RRD-CD patient was 11.42 times (3.54-46.80) more likely to experience post-PPV AL elongation of more than 1 mm [P<0.001, Akaike information criterion (AIC)=92.33, area under the curve (AUC)=0.839]. CONCLUSION: RRD-CD patients are very likely to have a postoperative elongation of AL. The primary intraoclular lens implantation using presurgery AL data may cause a significant refractive error in RRD-CD patients who underwent PPV.     

Air tamponade and without heavy liquid usage in pars plana vitrectomy for rhegmatogenous retinal detachment repair

AIM: To report the results of rhegmatogenous retinal detachment (RRD) repair after pars plana vitrectomy (PPV) without operative use of heavy liquid, and utilizing air tamponade in selected cases. METHODS: RRD patients without severity of proliferative vitreoretinopathy C2 or more underwent PPV without operative use of heavy liquid, and utilizing air tamponade were consecutively enrolled. Alternative postoperative facedown position or lateral position was required for 3-5d. RESULTS: Totally 36 eyes of 36 patients (24 males, 66.7%) aged 53.8±10.9y underwent this modified surgery. The mean number of retinal break was 2.1±1.3. Most of the eyes (29, 80.6%) had retinal detachment involving more than one quadrant. Twenty-two (61.1%) eyes with cataract had combined phacoemulsification and intraocular lens implantation. The mean follow up time was 4.6±1.8mo. Two eyes with retinal redetachment underwent a second retinal repair surgery with silicone oil tamponade, yielding the primary reattachment rate to 94.4% (34/36). Six (16.7%) eyes had intraocular pressure higher than 25 mm Hg. The visual acuity (logMAR) improved from 0.98±0.74 preoperatively to 0.52±0.31 postoperatively (P<0.001). CONCLUSION: The success rate of this modified retinal repair surgery is comparable with traditional surgery. This technique can be considered for certain retinal detachment patients, since its apparent advantages included lower surgical complications, reduced surgery expenditure, shorter time for postoperative facedown position, and avoiding silicone oil removal surgery.     

Acute endophthalmitis following 23-gauge sutureless transconjunctival vitrectomy

We report a case that developed acute postoperative endophthalmitis after transconjunctival sutureless vitrectomy using the 23-gauge system. A 66-year-old man underwent non-sutured 23-gauge pars plana vitrectomy for epimacular membrane. Since the patient developed signs of acute endophthalmitis and decreased visual acuity to counting fingers on the second postoperative day, re-vitrectomy with silicone oil was performed. The patient responded well to re-vitrectomy, injection of silicone oil and intravitreal antibiotic injections. Methicillin resistant Staphylococcus epidermidis was cultured from vitreous samples. Silicone oil was extracted at 11 months. The patient remains stable at 14 months with a final visual acuity of 20/50.     

改良穿刺放液在23G玻璃体切除治疗脉络膜脱离型视网膜脱离中的疗效

目的：观察巩膜全层切开、原位穿刺放液术在微创玻璃体切除术治疗脉络膜脱离型视网膜脱离中的安全性和临床疗效。

方法：临床病例回顾性分析。纳入2015-04/2017-04江苏省人民医院眼科住院治疗的脉络膜脱离型视网膜脱离患者20例20眼,所有患者均接受改良巩膜穿刺放液联合23G微创玻璃体切割术治疗。观察术中穿刺放液的成功率,手术前后视力、眼压变化情况,以及手术后视网膜复位率等情况。

结果：所有手术均一次顺利放出脉络膜上腔液体。患者术后视力较术前视力提高,差异有统计学意义(P<0.01)。术前眼压7.00±2.05mmHg,术后3mo时平均眼压为15.38±2.66mmHg,两者比较差异有统计学意义(P<0.01)。初次手术视网膜复位率为90%(18/20),最终视网膜复位率为95%(19/20)。

结论：改良巩膜穿刺放液在微创玻璃体切割术治疗脉络膜脱离型孔源性视网膜脱离中可简化手术操作,降低手术难度,减少术中并发症的发生。     

曲安奈德玻璃体内注射联合23G微创玻璃体切割术治疗脉络膜脱离型视网膜脱离的疗效分析

目的　探讨曲安奈德玻璃体内注射联合２３Ｇ微创玻璃体切割术治疗脉络膜脱离型视网膜脱离的疗效。方法　２０１２年１月至２０１３年１月在我院就诊的２８例脉络膜脱离型视网膜脱离患者,经过术前短期糖皮质激素治疗后,行２３Ｇ微创玻璃体切割术治疗,术中联合玻璃体内注射曲安奈德４ｍｇ,术后随访６～１２个月,观察术后视力恢复、视网膜复位和并发症发生情况。结果　一次手术视网膜解剖复位率为８９．３％,再次术后视网膜解剖复位率１００．０％。术前ＬｏｇＭＡＲ视力为１．９８±０．５０,术后ＬｏｇＭＡＲ视力为１．１７±０．４０,差异有统计学意义（ｔ＝８．３７１,Ｐ＜０. ０５）。末次随访眼压（１６．２±３．７）ｍｍＨｇ（１ｋＰａ＝７．５ｍｍＨｇ）,与术前眼压（６．４±２．３）ｍｍＨｇ相比,差异有统计学意义（ｔ＝１７. ６１３,Ｐ＜０．０５）。术后有１５例出现一过性高眼压,３例白内障加重,１例发生后发性白内障,５例术后少量结膜下出血。结论　２３Ｇ微创玻璃体切割术联合术中曲安奈德玻璃体内注射治疗脉络膜脱离型视网膜脱离是安全有效的。     

25G玻璃体切除联合空气填充术治疗孔源性视网膜脱离

目的:观察玻璃体切除联合空气填充术治疗孔源性视网膜脱离的临床疗效,评价空气填充的有效性及安全性。方法:对2017-08/2018-12就诊于遵义市第一人民医院的孔源性视网膜脱离并接受玻璃体切除联合空气填充术的患者30例30眼进行回顾性分析,观察术眼术前、术后1 wk,1 mo最佳矫正视力(BCVA,LogMAR)、眼压、术后视网膜复位情况及术后并发症情况等。结果:术前,术后1wk,1mo BCVA分别为0.87±0.71、0.64±0.36、0.37±0.22,手术前后术眼BCVA有差异(F=3.74,P=0.047)。术前,术后1wk,末次随访眼压分别为13.61±3.57、15.74±4.84、14.05±2.88mmHg,手术前后眼压无差异(F=4.13,P=0.051)。术后1wk视网膜复位率97%(29/30)。术后OCT监测1眼出现持续视网膜下积液,术后3mo积液吸收。结论:玻璃体切除联合空气填充术治疗孔源性视网膜脱离疗效确切,术后恢复快,提高视觉质量,同时减少患者经济负担。     

27G与25G微创玻璃体切割术治疗孔源性视网膜脱离的对比分析

目的　对比分析27G与25G微创玻璃体切割术（pars plana vitrectomy,PPV）治疗原发性孔源性视网膜脱离（rhegmatogenous retinal detachment,RRD）效果,并探讨27G PPV治疗RRD的安全性及有效性。方法　回顾分析2015 年5 月至2017 年6 月我院开展的微创PPV治疗RRD患者共92例,其中25G组58例,27G组34例。对比分析两组手术时间、视网膜复位率、视力改善及并发症等。结果　25G组手术时间为（56.7±35.9）min,27G组为（55.7±36.1）min（F=0.049,P=0.852）。单次手术视网膜复位率,25G组为94.8%,27G为91.2%,差异无统计学意义（P=0.666）。25G组与27G组末次随访最佳矫正视力（best corrected visual acuity,BCVA）均较术前改善,两组间视力改善率（改善＞0.2 LogMAR）差异无统计学意义（χ²=1.860,P=0.173）。两组均无严重并发症发生。25G组有2眼（3.4%）发生医源性视网膜裂孔,27G组有1眼（2.9%）发生医源性视网膜裂孔。术后一周内,高眼压（>25 mmHg）（1 kPa=7.5 mmHg）发生率25G组为25.9%,27G组为11.8%（χ²=3.009,P=0.083）。两组均未观察到感染性眼内炎、脉络膜脱离等严重并发症。结论　27G微创PPV在手术时间、视网膜复位率、视力改善及并发症方面与25G微创PPV无显著差异。27G微创PPV是治疗RRD的安全有效的手术方式。     

Multimodal imaging of eyes with metamorphopsia after vitrectomy for rhegmatogenous retinal detachment

Purpose:To assess the retinal features in eyes with postoperative metamorphopsia (POM) following rhegmatogenous retinal detachment (RRD) repair using multimodal imaging (MMI).Methods:In this cross-sectional; case-control study, patients after successful RRD repair following 25-gauge vitrectomy, clear vitreous cavity, and corrected distance visual acuity (CDVA)>20/200 were categorized using Amsler chart: cases with POM and controls without POM. MMI was performed on swept-source platform (Triton, Topcon Inc) and the confocal scanning laser ophthalmoscope system (Spectralis HRA, Heidelberg). The measures assessed were CDVA, morphological features on optical coherence tomography, autofluorescence, and multicolor imaging (MCI).Results:Thirty-nine eyes were included in each group. Cases had greater number of eyes with total RRD (P = 0.029) preoperatively; abnormal foveal contour (P = 0.036), ellipsoid zone (EZ) disruption (P < 0.001) and poorer postoperative CDVA (P = 0.046) as compared to controls. Outer retinal folds and retinal shift (unintentional translocation of retina after reattachment surgery for RRD) did not differ significantly between the groups (P = 0.48 and 0.35, respectively). On MCI, the distribution of detected ERM was similar between the groups (P = 0.25). Postoperative CDVA was significantly worse in eyes with POM.Conclusion:POM is affected by extent of RRD, postoperative foveal contour, and EZ status but not by retinal shift.     

孔源性视网膜脱离并发脉络膜脱离患者的角膜内皮形态学参数

目的：探讨孔源性视网膜脱离并发脉络膜脱离(RRD-CHD)患者的角膜内皮细胞形态学参数变化。

方法：连续收集RRD-CHD患者70例70眼,分为无高度近视组(A组)38眼38眼、高度近视组(B组)32例32眼,另收集正常组(C组)36例36眼。使用角膜内皮镜检测各组角膜内皮细胞最小面积(S_min)、最大面积(S_max)、平均面积、平均密度(CD)、细胞面积标准差(SD)、变异系数(CV)及六角形细胞比例(HG)。

结果：RRD-CHD患者和正常组的角膜内皮细胞CD、HG均有差异(P<0.001)。A组的CD与B组、C组均有差异(P<0.05),B组与C组有差异(P<0.001)。在A组中,SD、CV与眼轴(r_s=-0.426、0.494, 均P<0.01),CD与眼压、眼轴(r_s=-0.025、0.368, 均P<0.05),HG与病程(r_s=0.552, P<0.05)均相关。在RRD-CHD患者中,SD、CV与眼轴(r_s=0.236、0.159, 均P<0.05),HG与病程(r_s=0.142, P<0.05),S_max与眼压(r_s=-0.314, P<0.01)均相关。

结论：RRD-CHD患者持续低眼压状态下角膜内皮细胞的HG和CD均明显降低,眼轴、病程和眼压可影响角膜内皮的形态学参数。