25G经结膜无缝合巩膜切口与常规20G巩膜切口愈合的实验研究

目的：观察比较25G经结膜无缝合巩膜切口与常规20G巩膜切口的愈合情况。 方法：版纳实验用小型猪4只，采用随机对照的方法，选择一只眼行25G巩膜切开术（25G组），另一眼行常规20G玻璃体手术（20G组）。术后0d、10d、20d、60d分别观察大体和石腊切片苏木素-伊红（HE）染色，比较两组巩膜切口的愈合情况。 结果：25G组的巩膜切口明显小于20G组。术后第1天，20G组结膜充血较25G组明显。25G组的巩膜切口术后10d已基本愈合，仅有少量炎症细胞。20G组的巩膜切口在术后20d仍未完全愈合，有大量的炎症细胞浸润。术后60d两组切口均无炎症细胞浸润。术后，25G组中1个切口，20G组中2个切口可见玻璃体嵌顿；25G组中2个切口．20G组中4个切口可见纤维组织内生。 结论：与20G手术相比，25G手术巩膜切口具有创伤小、愈合快、炎症反应轻的优点。     

25-gauge scleral tunnel transconjunctival vitrectomy

PURPOSE: To compare the intraocular fluid leakage rate between 25-gauge (25G) transconjunctival vitrectomy with scleral tunnels and standard 25G transconjunctival vitrectomy. DESIGN: Single-center, retrospective, interventional case series. METHODS: Transconjunctival vitrectomies were conducted by the use of only 25G instruments with peripheral vitrectomy. Standard 25G vitrectomy was conducted in 542 eyes and 25G vitrectomy with scleral tunnels in 337 eyes. The scleral tunnel was created by inserting trocars at an oblique angle. RESULTS: The intraocular fluid leakage rate was significantly lower (Fisher exact probability test: P < .0001) when scleral tunnels were used in 25G vitrectomy (1%, five of 337 eyes) compared with standard 25G vitrectomy (9%, 50 of 542 eyes). The wound leakage rate was significantly lower when using (rather than not) scleral tunnels in 25G vitrectomy, both without air-gas (P = .0258) and with air exchange (P = .0007). CONCLUSION: The use of scleral tunnels in 25G transconjunctival vitrectomy reduces the frequency of wound leakage even when the peripheral vitreous is removed.     

27G微创玻璃体切除手术的发展及应用

自二十世纪初25 G、23 G无缝线玻璃体切除术的相继推出,已将我们带入玻璃体视网膜手术的微创时代约有10余年历史。与传统20 G三通道玻璃体切除术相比,25 G、23 G无缝线微创玻璃体切除术不仅缩小巩膜切口,而且还大大简化了手术程序,缩短了手术时间及降低了手术并发症。因此,在过去十余年时间里,越来越多的医生由传统的20 G玻璃体切除术转向25 G、23 G玻璃体切除术。但随着微创玻璃体切除术的普及,无缝线巩膜切口的相关并发症也随之增多。本着“越小越好”的理念,眼科学者开始研究下一代玻切手术,并且得益于不断更新换代的高速玻切机、高通量的照明光源、更精细的制造技术和清晰广角镜的发展,日本学者Oshima于2010年正式推出了27G玻璃体切除术。27 G玻璃体切除术较之前的微创玻璃体切除术切口更小,切割速率更高,带给眼底外科医生全新的体验。目前27 G甚至更细的玻璃体切除术尚处在继续革新之中,围绕其优缺点、适应证及未来发展也逐渐成为大家关注讨论的焦点。本文在此结合笔者27 G玻璃体切除术经验,对27 G微创玻璃体切除术玻璃体切除术进行了一个简要的综述。     

23G玻切头代替眼内膜剪用于20G玻璃体切割术治疗晚期PDR

目的：探讨在晚期增生性糖尿病视网膜病变（advanced proliferative diabetic retinopathy,PDR）20G玻璃体切割术中是否可应用23G玻璃体切割头代替眼内膜剪。方法：前瞻性非对照病例研究。对27例27眼经眼底检查和B超确诊为糖尿病视网膜病变Ⅵ期患者施行20G玻璃体切割术,术中以23G玻璃体切割头代替眼内膜剪清除新生血管膜,术毕完成全视网膜光凝,17眼灌注液填充,6眼填充12% C3F8,4眼填充硅油。随访3mo。分析患者玻璃体手术起止时间、术中发生的医源性裂孔数、手术中视网膜出血需电凝的次数,最佳矫正视力（BCVA）、视网膜复位情况。结果：手术时间为35～120（平均79.19±29.82）min; 术中发生医源性裂孔共2例（7%）。术后随访3mo,BCVA〉0.1者9眼,0.05～0.1者10眼,〈0.05者8眼。视网膜在位25眼（93%）,2眼术后硅油下视网膜仍未完全复位。结论：在20G玻璃体切割术治疗晚期PDR时,完全可以用23G玻璃体切割头代替眼内膜剪清除新生血管膜。     

23G与25G＋微创玻璃体切除术治疗玻璃体积血的临床对比观察

目的：对比观察23G、25G＋经结膜免缝合玻璃体切除术（TVS）治疗玻璃体积血的安全性和有效性。方法对比分析2013年3月至2014年3月因玻璃体积血在我院行两种不同微创玻璃体切除术（23G和25G＋）患者的临床资料,采用t检验或秩和检验以及χ2检验对比观察手术时间、切口闭合情况、术后眼压、术后视力及并发症等。结果共计45例（47只眼）,其中21例（22只眼）行23G微创玻璃体切除患者术（23G组）,24例（25只眼）行25G＋微创玻璃体切除术（25G＋组）;23G组手术时间为35～94 min,平均55．4 min;25G＋组手术时间为30～85 min,平均47．6 min;差异无统计学意义（ P ＝0．105）。23G组、25G＋组手术切口自然闭合比率分别为45．5％、80．0％,缝合率分别54．5％、20．0％,差异有统计学意义（ P ＝0．018）。术后第1天23G组眼压为（9．1±3．8） mm-Hg,25G＋组眼压为（10．2±2．6）mmHg,差异无统计学意义（ P ＝0．712）,术后第3天23G组眼压为（10．3±4．1） mmHg,25G＋组眼压为（10．9±3．7）mmHg,差异无统计学意义（ P ＝1．000）,术后1周23G组眼压为（14．3±6．9） mmHg,25G＋组眼压为（15．7±6．3）mmHg,差异无统计学意义（ P ＝0．371）;23G组术后视力改善情况与25G＋组无统计学差异（ P ＝0．807）;23G组术后发生视网膜脱离1例,切口渗漏1例,复发玻璃体积血3例;25G＋组术后发生视网膜脱离2例,切口渗漏2例,复发玻璃体积血1例;两组发生率差异均无统计学意义（ P ＝1．000、1．000、0．328）。结论25G＋TVS与23G TVS均是有效的玻璃体积血治疗方法,25G＋TVS切口自然闭合率更好,其他并发症发生率无差异。     

Untoward outcomes in 25-gauge versus 20-gauge vitreoretinal surgery

PURPOSE: This study compares the incidence of complications in eyes undergoing 25-gauge versus 20-gauge vitreoretinal procedures. METHODS: Retrospective case series. A chart review of consecutive patients who underwent primary 25-gauge (129 eyes) and 20-gauge (129 eyes) vitreoretinal surgery by four surgeons at a single center between September 2002 and November 2005 was conducted. RESULTS: Mean follow-up was 9.1 +/- 4.9 months in 25-gauge eyes and 14.3 +/- 8.4 months in 20-gauge eyes (P < 0.01). Intraoperative complications were mainly rhegmatogenous in nature and occurred at statistically similar incidence (4.7% in 25-gauge eyes, 6.9% in 20-gauge eyes). Postoperative complications that were significantly associated with surgical method included hypotony and serous choroidal effusions (7.9% in 25-gauge eyes, 1.6% in 20-gauge eyes, P = 0.02). Other postoperative complications noted included retinal tears and detachments (5.4% in 25-gauge eyes, 4.7% in 20-gauge eyes), persistent vitreous hemorrhage (5.4% in each group), and new vitreous hemorrhage (3.9% in 25-gauge eyes, 0.8% in 20-gauge eyes). Endophthalmitis was noted only in 25-gauge eyes in 2 cases (1.6%). Cataract progression occurred at similar rates in both groups (46%). CONCLUSION: 25-gauge surgery is associated with a significantly greater incidence of postoperative serous choroidal effusions and hypotony. Of particular concern in 25-gauge surgery is the increased risk of associated endophthalmitis. Operative indications and case selection may be important in minimizing the tendency toward certain postoperative events.     

27G与25G微创玻璃体切割术治疗孔源性视网膜脱离的对比分析

目的　对比分析27G与25G微创玻璃体切割术（pars plana vitrectomy,PPV）治疗原发性孔源性视网膜脱离（rhegmatogenous retinal detachment,RRD）效果,并探讨27G PPV治疗RRD的安全性及有效性。方法　回顾分析2015 年5 月至2017 年6 月我院开展的微创PPV治疗RRD患者共92例,其中25G组58例,27G组34例。对比分析两组手术时间、视网膜复位率、视力改善及并发症等。结果　25G组手术时间为（56.7±35.9）min,27G组为（55.7±36.1）min（F=0.049,P=0.852）。单次手术视网膜复位率,25G组为94.8%,27G为91.2%,差异无统计学意义（P=0.666）。25G组与27G组末次随访最佳矫正视力（best corrected visual acuity,BCVA）均较术前改善,两组间视力改善率（改善＞0.2 LogMAR）差异无统计学意义（χ²=1.860,P=0.173）。两组均无严重并发症发生。25G组有2眼（3.4%）发生医源性视网膜裂孔,27G组有1眼（2.9%）发生医源性视网膜裂孔。术后一周内,高眼压（>25 mmHg）（1 kPa=7.5 mmHg）发生率25G组为25.9%,27G组为11.8%（χ²=3.009,P=0.083）。两组均未观察到感染性眼内炎、脉络膜脱离等严重并发症。结论　27G微创PPV在手术时间、视网膜复位率、视力改善及并发症方面与25G微创PPV无显著差异。27G微创PPV是治疗RRD的安全有效的手术方式。     

23G和20G玻璃体切割手术治疗IEM的对比研究

目的：比较 23G经结膜无缝线玻璃体手术与传统20G玻璃体手术治疗特发性黄斑前膜（IEM）的疗效。 方法：将2008-03/2011-06在我院诊断为黄斑前膜并需行玻璃体切割的连续病例56例56眼随机分为23G组与20G组,分别行23G及20G玻璃体切割手术。统计分析术后1d,1wk,3mo时最佳矫正视力、眼压、术中术后并发症、手术时间及术后前房炎症反应及眼部刺激征的严重程度,术后随访5～22（平均16）mo。 结果：23 G组术后3mo内平均对数视力log MAR逐步提高,三个时间点分别为1.78±0.94,1.51±0.88,1.48±091,术后第1d,1wk,3mo视力与术前相比有统计学意义(t=3.3917,P=0.003;t=11.1779,P=0.0000;t=4.3424,P=0.0000);20G组术后平均对数视力也逐步提高,三个时间点分别为2.11±1.00,1.93±1.02,1.64±1.00,术后第1wk,3mo视力与术前相比有统计学意义(t=2.3578,P=0.033;t= 3.5552,P=0.003)。两组术后3mo内三个时间点视力差异均无统计学意义(t=0.9582,P=0.34;t=12761,P=0.211;t=0.4897,P=0.628)。23G组术后3个时间点眼压分别为11.62±9.7,15.86±6.6,16.84±56mmHg,20G组术后3个时间点眼压分别为18.56±7.71,15.33±5.21,14.72±3.56mmHg,两组术后第1d眼压差异有统计学意义（P<0.001）。 23G组平均手术时间41.20±7.47分,少于20G组平均手术时间52.28±7.11分,两者比较差异有统计学意义（P<0.001）。两组术后无视网膜脱离、黄斑前膜复发及眼内炎的发生。23G组术后的炎症反应及刺激症状明显轻于20G组。 结论：23G TSV治疗IEM简化了手术步骤,增加了患者舒适度,提高了手术效率和质量,实现了玻璃体切割手术的微创化,值得应用。     

25G经结膜无缝合玻璃体切割术系统在先天性白内障中的应用

目的 评价25G经结膜无缝合玻璃体切割手术系统(TSV25G)治疗先天性白内障手术中应用的临床疗效.方法 回顾分析20例29只眼(2～12岁)行超声乳化白内障吸除、TSV25G晶状体后囊膜环形切开前部玻璃体切割和一期人工晶状体植入手术治疗的先天性白内障患者的临床资料.手术后随访2个月至1年,观察术后视力以及后囊膜混浊、虹膜粘连、人工晶状体偏位等术后并发症情况.结果 20例(29只眼)术后视力明显改善,表现为明显视物追踪,视力提高.无虹膜夹持、后囊膜混浊、虹膜后粘连、继发青光眼、人工晶体偏位、黄斑囊样水肿和视网膜脱离等并发症发生.结论 行TSV25G晶体后囊膜环形切开前部玻璃体切割手术应用于先天性白内障的手术治疗,具有手术时间短、创伤小、术后恢复快等优点,能有效抑制后发障发生,有助于视功能的恢复.     

23G微创与20G传统玻璃体手术的短期临床对比研究

目的比较23 G经结膜无缝线玻璃体手术与传统20 G玻璃体手术后短期内(1周)眼压、视力、手术时间及术后并发症。设计回顾性比较性病例系列。研究对象随机选择北京同仁医院2010年1月至2011年3月间行23 G玻璃体手术的15例(15眼)玻璃体积血患者及同期行20 G玻璃体手术18例(18眼)玻璃体积血患者。方法回顾上述患者住院病历资料,将其分为23 G微创和20 G传统玻璃体手术两组,分析两组患者术前及术后第1、3、7天眼压、视力以及手术时间、术后是否发生低眼压、眼内炎等并发症。主要指标眼压及视力,手术时间。结果术后33眼(100%)视网膜均复位。23 G组术后1周内眼压均低于20 G组,前者术后三个时间点眼压由低逐渐增加,分别为(10.87±3.48)、(11.53±4.84)、(11.80±5.68)mm Hg,后者术后三个时间点眼压由高逐渐降低,分别为(19.56±7.71)、(15.33±5.21)、(14.72±3.56)mm Hg,两组术后第1天眼压差异有统计学意义(t=4.0281,P=0.000);23 G组术后1周内平均对数视力logMAR逐步提高,三个时间点分别为2.11±1.00、1.93±1.02、1.64±1.00,术后第3、7天视力与术前相比有统计学意义(t=2.3578,P=0.033t;=3.5552,P=0.003),20 G组术后1周内平均对数视力也逐步提高,三个时间点分别为1.78±0.94、1.51±0.881、.48±0.91,术后三个时间点视力与术前相比差异均有统计学意义(t=3.3917,P=0.003t;=11.1779,P=0.000t;=4.3424,P=0.000),两组术后1周内三个时间点视力差异无统计学意义(t=0.9582,P=0.345t;=1.2761,P=0.211;t=0.4897,P=0.628);23 G组平均手术时间(37.20±7.47)分,少于20 G组平均手术时间(49.28±8.11)分,两者比较差异有统计学意义(t=4.4152,P=0.000);23 G组术后低眼压2例(13.33%),20 G组术后低眼压1例(5.56%),两组低眼压差异有统计学意义(χ2=8.6429,P=0.003)。两组均未发生眼内炎和视网膜脱离。结论 23 G微创玻璃体切除术比传统20G玻璃体切除术明显减少了手术时间且降低了术后眼压上升的风险,术后视力恢复无差异,是一种较安全有效的玻璃体手术方式,但术后早期低眼压发生率较高是该术式的主要并发症。     

Comparison of visual function after epiretinal membrane removal by 20-gauge and 25-gauge vitrectomy

PURPOSE: To compare the efficacy and safety of 25-gauge vitrectomy with 20-gauge vitrectomy for macular pucker. DESIGN: Randomized clinical study. METHODS: Sixty-seven eyes (67 patients) with macular pucker were prospectively and randomly assigned to undergo 20-gauge vitrectomy or 25-gauge vitrectomy as a control group. Main outcome measurements consisted of best-corrected visual acuity (BCVA), mean induced astigmatism, total operation time, and postoperative complications. RESULTS: The mean BCVA at baseline and at one month and six months after surgery was 20/78, 20/62, and 20/42, respectively, in the 20-gauge group, and 20/85, 20/45, and 20/40 in the 25-gauge group. A significant difference in change in the logarithm of the minimal angle of resolution of BCVA between 20-gauge and 25-gauge was found at one month (-0.10 vs -0.269, P < .001), but not at six months (-0.327 vs -0.276, P > .01). CONCLUSIONS: If faster visual improvement is desired, 25-gauge vitrectomy may be preferable to 20-gauge vitrectomy for macular pucker.     

20G联合23G玻璃体切除术在外伤性晶状体完全后脱位中的应用

目的探讨20G联合23G玻璃体切除技术在外伤性晶状体完全后脱位中的应用及临床疗效。方法回顾分析2013年1月-2013年12月行20G联合23G玻璃体切除术治疗外伤性晶状体完全后脱位共23例的临床资料,观察手术效果及并发症发生的情况。结果 21例（21眼）完成玻璃体联合晶状体切除。术后至随访期结束：86.96%的病例矫正视力有不同程度的提高;术前存在继发性青光眼者术后眼压均控制在正常范围;术后未出现持续性低眼压、感染性眼内炎等严重并发症。结论 20G联合23G玻璃体切除技术是治疗外伤性晶状体完全后脱位的安全、有效方法。     

25G玻璃体切除手术系统在闭合性眼外伤玻璃体积血手术中的应用

目的评估25G经结膜无缝合玻璃体切除手术系统(TSV 25G)在闭合性眼外伤玻璃体积血手术治疗中的应用价值。方法回顾性分析应用TSV 25G治疗20例20眼闭合性跟外伤玻璃体积血的临床资料。结果20例中除1例外,余均顺利完成手术,手术时间30～44min,平均时间36min。1例术中穿刺口漏水,缝合1针。手术后住院时间3～7d,平均4.5d;12例视力恢复至0.8以上占60.00%,其余8例合并视神经视网膜脉络膜挫伤,视力也有不同程度的提高。结论TSV 25G应用于闭合性眼外伤玻璃体积血手术治疗,操作安全且手术时间短,效果较好。     

27G+/25G+微创玻璃体切割手术治疗玻璃体视网膜疾病的比较

目的:对比分析25G+与27G+微创玻璃体切割手术治疗玻璃体视网膜疾病的疗效及安全性。方法:回顾性分析2019-03/2022-04于我院行玻璃体切割手术的玻璃体视网膜病变患者89例89眼的临床资料,根据手术方式分为A组(45例45眼,行25G+微创玻璃体切割手术)和B组(44例44眼,行27G+微创玻璃体切割手术),分析两组患者术中玻璃体切割时间和手术完成时间、手术前后最佳矫正视力(BCVA)和眼压情况及术后主观舒适度和并发症情况。结果:两组术中玻璃体切割时间无差异(P>0.05),但B组手术完成时间短于A组(35.50±14.27min vs 41.73±14.25min,P=0.042)。两组术后BCVA均优于术前(P<0.05),但两组间无显著差异(P>0.05)。两组术后眼压均低于术前(P<0.05),且术后1、7d A组眼压略低于B组(P<0.05)。术后1d, A组主观舒适度评分高于B组(6.13±1.20分vs 3.45±1.17分,P<0.001);术后7d,两组主观舒适度评分无差异(2.18±1.01分vs 1.93±0.87分,...     

Outcomes of transconjunctival sutureless 27-gauge vitrectomy for vitreoretinal diseases

AIM: To evaluate the safety and efficacy profile of 27-gauge (27G) pars plana vitrectomy (PPV) for the treatment of various vitreoretinal diseases. METHODS: The clinical outcomes of 61 eyes (58 patients) with various vitreoretinal diseases following 27G PPV were retrospectively reviewed. RESULTS: Surgical indications included rhegmatogenous retinal detachment (n=24), full-thickness macular hole (n=12), diabetic retinopathy (n=11), vitreous hemorrhage (n=6), Eales disease (n=4), pathological myopia-related vitreous floater (n=2), and macular epiretinal membrane (n=2). The mean follow-up was 166.4±61.3d (range 98-339d). The mean logMAR best-corrected visual acuity (BCVA) improved from 1.7±1.1 [0.02 decimal visual acuity (VA) equivalent] preoperatively to 1.2±1.0 (0.06 decimal VA equivalent) at the last postoperative visit (P<0.001). The mean operative time was 49.9min. With the exception of complicated cataract in one eye, no intraoperative complications were encountered. No case required conversion to conventional 20-, 23- or 25G instrumentation in all surgical maneuvers except for silicone oil infusion, which required a 25G oil injection syringe. Postoperative complications included transient ocular hypertension, vitreous hemorrhage, persistent intraocular pressure elevation, subconjunctival oil leakage, and recurrent retinal detachment. No cases of hypotony, endophthalmitis, and sclerotomy-related tears were observed. CONCLUSION: The current results suggest that 27G PPV system is a safe and effective treatment for various vitreoretinal diseases. When learning to perform 27G PPV, surgeons may encounter a learning curve and should gradually expand surgical indications from easy to pathologically complicated cases.     

Pars plana vitrectomy for the repair of primary, inferior rhegmatogenous retinal detachment associated to inferior breaks. A comparison of a 25-gauge versus a 20-gauge system

Background

To compare anatomical, functional outcomes and complications of high-speed 25-gauge (G) pars plana vitrectomy (PPV) versus 20-G PPV for the management of primary inferior rhegmatogenous retinal detachment (RRD) associated to inferior breaks/holes.

Methods

Eighty-five eyes from 85 patients with a minimum follow-up of 3 months were retrospectively evaluated. Forty-one patients underwent 25-G and 44 patients underwent 20-G PPV. All patients underwent PPV with fluid-air exchange, sulfur hexafluoride (SF6) 20 % gas tamponade and laser or cryo retinopexy.

Results

The mean follow-up interval was 6.51(±2.32) and 6.63 (±2.58) months in the 25-G and 20-G groups respectively. Single-operation success rate was 92.7 % for the 25-G group and 81.8 % for the 20-G group (P?=?0.24). Post-operative hypotony was observed in no case. Redetachment occurred in 3 eyes operated on with 25-G and in 8 eyes operated on with 20-G system. All retinas were attached at final follow-up. Logarithm of the minimum angle of resolution visual acuity significantly improved from 0.69?±?0.76 to 0.33?±?0.37 in the 25-G and from 0.47?±?0.59 to 0.21?±?0.28 in the 20-G group (P?=?0.0007 and P?<?0.0001 respectively).

Conclusions

High-speed PPV and SF6 gas tamponade using either 25-G or 20-G PPV system, yields similar single operation anatomical success rates for the repair of uncomplicated, primary inferior RRDs associated to inferior breaks.     

Endophthalmitis after 25-gauge and 20-gauge pars plana vitrectomy: incidence and outcomes

PURPOSE: To compare the rates of endophthalmitis after 20-gauge versus 25-gauge pars plana vitrectomy (PPV) and to investigate clinical features of, and visual acuity outcomes, for patients with endophthalmitis after PPV. METHODS: A computerized database search was performed at each author's institution to identify all patients who underwent PPV by any of the authors between January 1, 2005, and December 31, 2006, and were subsequently treated for endophthalmitis. In addition, all patients who underwent PPV and were subsequently treated for endophthalmitis at Pennsylvania State College of Medicine (Hershey, PA) and Bascom Palmer Eye Institute (Miami, FL) during the study period were included. The medical records of these patients were reviewed to confirm that the endophthalmitis was associated with PPV and to collect clinical data to meet the study objectives. RESULTS: The incidence of endophthalmitis during the study period was 2 cases per 6,375 patients (or 1 case per 3,188 patients; 0.03%) for 20-gauge PPV compared with 11 cases per 1,307 patients (or 1 case per 119 patients; 0.84%) for 25-gauge PPV (P < 0.0001). Of 11 eyes that developed endophthalmitis after 25-gauge PPV, 9 received endophthalmitis prophylaxis with subconjunctival cefazolin after surgery. Median intraocular pressure on postoperative day 1 was 13 mmHg (range, 5-27 mmHg). Median time between PPV and endophthalmitis presentation was 3 days (range, 1-15 days). Presenting vision was hand motions or better in all eyes. Initial treatment included vitreous tap and injection of antibiotics in nine eyes and PPV and injection of antibiotics in two. All patients received intraocular treatment with vancomycin, and 10 received ceftazidime treatment. Eight patients had final visual acuity of >/=20/400, and four had visual acuity of >/=20/63. Cultures were negative in three cases; no culture specimens were obtained in one case. Six of the seven isolates were coagulase-negative staphylococci, and one was enterococcus. Five of six isolates tested for sensitivity to vancomycin were sensitive, and both isolates tested for sensitivity to ceftazidime were sensitive. CONCLUSIONS: The rate of endophthalmitis after 25-gauge PPV was significantly higher than that after 20-gauge PPV. Endophthalmitis after 25-gauge PPV occurred within 15 days of PPV, was usually due to coagulase-negative staphylococci sensitive to vancomycin, and was associated with variable visual outcomes.     

Clinical presentation of a mixed 23-gauge infusion and 20-gauge pars plana technique for active silicone oil removal

AIM: To present with a clinical case series of a mixed 23-gauge infusion and 20-gauge pars plana technique for 5,700-centipoise silicone oil removal (SOR), and to discuss its efficacy and safety.METHODS: This is a retrospective, non-randomized controlled study. We performed SOR with 23-gauge infusion and 20-gauge active suction technique on 29 patients 29 eyes from April to October, 2011 (mixed group). During the surgeries, a 23-gauge sclerotomy was made for infusion and a 20-gauge sclerotomy was used for active silicone oil suction. Anterior segment optical coherence tomography (OCT) was applied for 23-gauge sclerotomy analysis 1 day post-operation. Traditional 20-gauge SOR was performed on another consecutive 29 patients 29 eyes, the control group (20G group).RESULTS: There were 2 eyes (6.9%) in mixed group and 5 eyes (17.2%) in 20G group which had recurrent retinal detachment after surgery. Hopytony (IOP≤6mmHg) occurred in 8 eyes (27.6%) of mixed group and in 10 eyes (34.5%) of 20G group post-operation, but all of them recovered to the normal level finally. There were no statistical significant differences. Final visual acuity was significantly increased after surgery in both groups. Anterior segment OCT images were acquired from 13 eyes of mixed group, and all of them had a proper wound apposition. But local ciliary detachment was found in 9 eyes (69%). It was hard to define the OCT image of the sclerotomies and ciliary body because of the serious conjunctival hemorrhages and chemosis in 20G group.CONCLUSION: This mixed technique is a convenient and effective way to remove high viscosity silicone oil. Compared with traditional 20-gauge SOR, it does not increase the risk of post-operative complications and has less conjunctival reactions.. Transient postoperative hypotony is common for this procedure and subclinical ciliochoroidal detachment is a probable cause.     

Comparison of 27-gauge versus 25-gauge vitrectomy results in patients with epiretinal membrane: 6-month follow-up

International Ophthalmology - To compare the 27G versus 25G vitrectomy in patients with epiretinal membrane (ERM). Sixty pseudophakic eyes of 60 consecutive patients treated by pars plana...     

Topical anesthesia in transconjunctival sutureless 25-gauge vitrectomy for macular-based disorders

PURPOSE: To evaluate the safety and feasibility of topical anesthesia in vitrectomy using the transconjunctival sutureless 25-gauge system (TSV 25G). METHODS: TSV 25G vitrectomy was performed prospectively in 46 eyes of 46 patients with macular-based disorders, including macular holes (n = 31), idiopathic epiretinal membranes (n = 11), and vitreoretinal traction syndrome (n = 4). Topical anesthesia was administered in each patient by instilling 2% Alcaine at 5 min intervals, three times before surgery. Additional Alcaine drops were given as a supplementation if needed during the operation. The levels of intraoperative analgesia were graded from 1 (adequate) to 3 (inadequate). RESULTS: Thirty-one patients (67.4%) tolerated the procedure well, with no additional anesthetic agent. Thirteen patients (28.3%) required additional topical anesthesia and 2 patients (4.3%) required a systemic sedative. Intraoperative pain occurred when the sclera was pierced by the microcannula and when sclera indentation was performed. No patient required additional retrobulbar or peribulbar anesthesia. There was no intraoperative complication which was specifically related to topical anesthesia. CONCLUSION: Topical anesthesia permits the successful management of some surgically less complex vitreoretinal disorders when the TSV 25G is used.