暴发性阴囊坏疽治疗9例体会

目的：探讨暴发性阴囊坏疽的治疗方法。方法：对9例患者均行外科清创、冲洗引流、抗感染等治疗，其中3例外暴露的睾丸暂置于浅表腔隙中，二期重建阴囊回纳睾丸，1例患者行高压氧治疗。结果：留置U形管引流者，重复清创手术的次数明显减少，体温及血常规恢复正常的时间较普通引流显著缩短，术后恢复迅速。结论：暴发性阴囊坏疽的治疗仍以清创及应用抗生素为主，术中多无须切除睾丸；条件许可，可配合高压氧治疗；U形多孔双向引流管在清创术后引流效果确切，对促进康复有明显优势。     

多孔负压引流在阴囊Fournier坏疽治疗中的应用

目的:探讨多孔负压引流在Fournier坏疽治疗中的临床价值并总结该病诊治方法。方法:回顾2005年1月~2015年4月我院收治的3例阴囊Fournier坏疽患者,总结诊疗经验并复习相关文献。结果:2例患者给予阴囊坏疽清创术,术后给予多孔负压引流术。术后患者双侧阴囊恢复正常大小,阴囊可见肉芽组织,渗液及坏死物逐渐消退。1个月后随访,阴囊创面基本愈合,至今未复发。另1例患者因自动出院失去随访。结论:广泛阴囊坏死组织清创+多孔负压引流对治疗Fournier坏疽的效果安全有效,值得推广。     

阴囊坏疽的阴囊重建

目的探讨阴囊坏疽的诊断、治疗及阴囊重建方法.方法 1992年1月～2004年9月,对15例阴囊坏疽进行临床资料分析,年龄23～80岁.创面细菌培养阳性14例,无菌生长1例,其中血培养阳性1例.均行抗感染、外科清创及引流等治疗.2例行高压氧治疗.清创术后根据情况采用皮瓣转移、植皮、直接缝合等方法行阴茎阴囊修复重建,其中2例高龄患者行睾丸去势术.结果住院时间21～34 d,平均26 d.所有患者术后创面均Ⅰ期愈合.获随访1～3年,平均1.5年.13例保留睾丸者阴囊外观满意,性功能正常,无睾丸萎缩发生.下肢、阴囊及腹股沟区无不适.结论阴囊坏疽确诊后应早期广泛清创并联合应用抗生素治疗,加强局部引流,有条件者可行高压氧治疗,根据具体情况重建阴囊.     

阴囊坏疽的诊断和治疗(附9例报告)

目的：探讨阴囊坏疽的诊断及治疗方法。方法：回顾性分析9例阴囊坏疽患者的临床资料，对9例患者均行早期多切口切开引流和广泛清创。结果：7例患者坏疽创面愈合良好，1例行二期睾丸切除术后愈合；1例死亡。患者生存率为88．8％。结论：阴囊坏疽的治疗以早期多切口切开引流、广泛清创、使用足量广谱抗生素、全身支持治疗及局部治疗、原发病治疗为主。注意卫生、保持局部清洁及提高卫生保健意识是其重要预防措施。     

封闭式负压引流技术辅助治疗阴茎、阴囊坏疽4例临床分析

目的:通过分析总结封闭式负压引流技术辅助治疗阴茎、阴囊坏疽的临床疗效,探讨该类疾病的最佳治疗方法。方法:收集整理2015年1月至2016年6月,收治的4例阴茎、阴囊坏疽患者的临床诊治资料,回顾分析其治疗过程中配合使用封闭式负压引流技术的方法及其疗效。4例患者均早期行广泛、彻底的阴囊、阴茎坏疽清创术,并静脉应用二联广谱抗生素,清创后为充分创面引流,应用封闭式负压引流(VSD),待创面清洁后,予以创面缝合。结果:4例患者经配合使用封闭式负压引流技术后,坏疽创面引流更加充分,阴囊、阴茎坏疽范围快速局限化,未出现睾丸坏死情况。4例患者均在坏疽创面清洁后,二期缝合,创面顺利愈合后出院。3个月后随访,局部创面愈合良好,无复发。结论:应用封闭式负压引流冲洗技术配合早期行广泛、彻底清创可有效促进坏疽范围的局限化,显著降低换药频率和缩短患者住院周期,是治疗阴茎阴囊坏疽的极为有效的辅助治疗手段。     

阴囊坏疽的治疗体会(附14例报告)

目的总结阴囊坏疽的治疗方法。方法2003年8月至2005年6月诊治阴囊坏疽14例，患者年龄27～74岁，平均48岁。阴囊坏疽并发肛周、阴茎坏疽者2例，并发肛周、阴茎、腹股沟区坏疽者10例，并发肛周、阴茎、腹股沟区、腹部皮下坏疽者2例。其中并发阴茎坏死3例，并发睾丸炎5例。14例细菌培养均为阳性。14例均采用Ⅰ期清创、阴囊成形、置管引流术，同时给予抗炎对症治疗。3例阴茎坏死者行阴茎全切、尿道造瘘术，2例腹部坏疽者行腹部皮下切开清创引流，5例睾丸炎者行单侧睾丸切除。结果12例阴囊成形术Ⅰ期愈合，2例尿道造瘘术患者痊愈出院。10例阴茎皮肤坏疽者1个月后阴茎植皮，痊愈出院。死亡2例。结论早期及时清创和抗炎对症治疗是治疗本病的关键，Ⅰ期清创、阴囊成形及置管引流是治疗阴囊坏疽的有效方法。     

阴囊坏疽行阴囊修复重建

目的总结阴囊坏疽的临床特征和诊治方法。方法复习2015年7月至2016年10月诊治的3例阴囊坏疽致阴囊缺损患者临床资料。结合文献资料分析和讨论阴囊坏疽的特征及治疗。结果所有患者均早期、反复清创、封闭负压引流、股前外侧穿支皮瓣转移修复重建,取得良好的效果。结论早期清创、引流后应用封闭负压引流技术,联合股前外侧穿支皮瓣转移是治疗阴囊坏疽致阴囊缺损修复重建的良好方法。     

Fournier坏疽的诊治(附16例报告)

目的　探讨Fournier坏疽的诊断及治疗。　方法　对 16例男性Fournier坏疽患者的临床资料进行分析。患者年龄 2 4～ 84岁 ,平均 5 1岁。其中阴囊坏疽 13例 ,阴茎皮肤坏疽 3例。细菌培养 14例 ,阳性 9例。 16例均行外科清创、引流、抗感染等治疗 ,4例行高压氧治疗。　结果　 13例经二期缝合痊愈出院 ,其中 2例 1个月后取皮瓣行阴茎、阴囊成形术。死亡 3例 ,其中 2例并发败血症 ,1例高龄患者早期出现肾功能受损而致多器官功能衰竭。　结论　治疗以早期广泛清创及应用广谱抗生素为主 ,加强局部引流 ,有条件者可行高压氧治疗。     

Fournier坏疽23例报告

目的:探讨Fournier坏疽的诊断治疗措施。方法:回顾性分析23例Fournier坏疽的诊断和治疗方法。23例患者外阴均红肿、疼痛,并迅速阴囊坏疽,并发不同程度的阴茎、肛周、会阴、腹股沟、下肢坏疽。23例患者分别采取早期清创术,切开引流,抗炎及高压氧治疗。Ⅱ期有11例行阴囊成形术,7例行阴茎阴囊植皮术,2例阴茎坏死者行阴茎切除术后尿道外口成形术。1例行膀胱造瘘术,1例行结肠造瘘术。结果:20例痊愈,3例死亡。结论:Fourn ier坏疽病情凶险,早期诊断、外科综合治疗是治愈的关键。     

封闭负压引流技术应用于阴囊坏疽患者中的临床疗效观察

目的:阴囊坏疽患者中应用封闭负压引流技术(vacuum-sealingdrainage, VSD)的临床疗效观察。方法:回顾性分析2010年1月—2020年1月青海红十字医院和华中科技大学同济医学院附属同济医院泌尿外科10年内不同时期收治的阴囊坏疽患者各20例共计40例为研究对象,分成VSD治疗组和常规换药对照组,VSD治疗组采用急诊Ⅰ期下腹部及会阴部坏死性筋膜炎清创术+VSD辅助治疗,同时给予全身联合抗感染及营养支持治疗,待引流液清亮后拆除敷料,创面干净后行二期直接缝合,总结VSD软组织缺损修复与重建的临床疗效。结果:阴囊坏疽患者经早期手术清创+VSD疗法较对照组相比,换药次数减少,住院时间缩短,住院总费用下降,技术操作简便,易于掌握,疗效远优于常规治疗,能够取得用传统方法治疗复杂创面无法达到的良好效果,治疗有显著性差异(P0.05)。结论:早期创面清创+VSD治疗联合抗生素应用及营养支持治疗阴囊坏疽,能够快速促进伤口的愈合,缩短治疗时间,减少换药次数,降低医疗费用,降低医务人员工作量,值得临床推广应用。     

Extensive Fournier's gangrene: a case report

We report a case of extensive Fournier's gangrene that could not be rescued despite emergent debridement. A 51-year-old man presented at another hospital with cough, diarrhea and abdominal pain. He was diagnosed with acute enteritis and hospitalized. The next morning, he became severely hypotensive and his scrotum was swollen and black. The perineal skin also was black. Septic shock and disseminated intravascular coagulation were suspected. He was transferred to our emergency room, and was immediately diagnosed with Fournier's gangrene and acute peritonitis. Computed tomographic scan revealed soft-tissue gas in the scrotum, the retroperitoneal cavity and the abdominal wall. Emergent debridement and laparotomy was performed. Gangrene was also seen at the intestinal wall and the peritoneum, however, resection of intestine was not done because of his poor performance status. Although potent antibiotics and catecholamine were administered, he died of multiple organ failure 29 hours after the operation. This is the first case of Fournier's gangrene extending into the abdominal cavity reported in the Japanese literature.     

Fournier坏疽五例报告

目的 探讨Ｆｏｕｒｎｉｅｒ坏疽的诊断和处理方法。方法 报告５例Ｆｏｕｒｎｉｅｒ坏疽的临床特点并进行文献复习。结果 ５例经清创引流,抗炎及对症治疗第,３例康复,随访１年无复发;死亡２例;结论Ｆｏｕｒｎｉｅｒ坏疽是一种累及阴囊、阴茎的感染性坏死性筋膜炎。及时正确的诊断,处理可减少其死亡率和并发症;超声显像,ＣＴ等技术有利于此病的早期发现;治疗原则为早期清创,引流,全身应用大剂量广谱抗生素等。     

Fournier's gangrene of the penis: a report of two cases

Fournier's gangrene is a rare disease involving the scrotum and penis with occasional extension up the abdominal wall. Both of our cases were unusual in that only the penis was involved. In addition, the occurrence of squamous cell carcinoma in an area previously affected by Fournier's gangrene has never been reported. The usual organism is an anaerobic streptococcus synergistic with some second organism. Early therapy is key, including debridement of the entire shaft of the penis distal to the devastated area, intravenous broad-spectrum antibiotics, and skin grafting.     

A case of Fournier's gangrene reconstructed using a rectus abdominis muscle flap

We encountered a case of Fournier's gangrene complicated with vesicorectocutaneous fistula that was treated with a pedicled rectus abdominis muscle flap (pedicled RA m-c flap). A 75-year-old man was admitted with consciousness disorder and swelling of the scrotum. The patient had noticed swelling of the scrotum 4 days before admission, but he had ignored this condition. The scrotum and the penis appeared necrotic. On the basis of clinical and radiological findings, we diagnosed this condition as Fournier's gangrene. Surgical debridement was performed in conjunction with the use of broad-spectrum antibiotics. After the patient's general condition was improved, the broad defect in the perineal tissue was covered with a pedicled rectus abdominis muscle flap. The flap was successful. In Japan, this is the first case of Fournier's gangrene complicated with vesicorectocutaneous fistula that was treated with a pedicled RA m-c flap. In order to determine whether plastic surgery after debridement shortens the duration of hospitalization, we reviewed the cases of 120 patients with Fournier's gangrene in Japan. We conclude that plastic surgery after debridement does not shorten the duration of hospitalization, however, this procedures is very useful to deep and broad defects by Fournier's gangrene.     

Management of Fournier's Gangrene: Review of 45 Cases

Purpose Fournier's gangrene is a fatal synergistic infectious disease with necrotizing fasciitis of the perineum and abdominal wall along with the scrotum and penis in men and the vulva in women. Methods The clinical and operative records of 45 patients with Fournier's gangrene during a 14-year period were analyzed. Results The etiology of the infection was identified in 39 patients. The most common causes were colorectal diseases and urogenital diseases. Four patients died with an overall mortality of 8.8%. The mortality rate was higher in patients with diabetes mellitus, but it was not statistically different. The age, duration of the symptoms, and the presence of rectal abscess were not found to be significant factors regarding mortality rate. Conclusions Surgery with extensive debridement of all necrotic tissue is the main stay of treatment.     

Fournier's gangrene

Over a 5-year period 43 men with severe classic Fournier's gangrene of the scrotum and perineum and in some cases of the abdominal wall were treated at King Edward VIII Hospital, Durban. There were 8 deaths, an overall mortality rate of 18,6%. The mortality rate was high (33%) when associated with diabetes mellitus and lower (14,7%) among non-diabetic patients. There was also an increased mortality rate when there was a delay in presentation (of over 6 days in the case of all the patients who later died). We have adopted a policy of aggressive surgical debridement and frequent revision, coupled with the use of broad-spectrum antibiotics.     

Minimal debridement in the treatment of Fournier's gangrene.

Scrotal and perineal gangrene of the male genitalia was first described by Fournier in 1883. Treatment of the disease remains surgical despite the availability of modern antibiotics. Many authors advocate a wide debridement of all tissue superficial to the involved fascial layers. We have reviewed our experience of using wide and minimal debridement as the surgical technique of choice. In our retrospective study, nine patients were diagnosed and treated over a 2-year period for Fournier's gangrene. The mean age was 65+/-28 years. Two patients were admitted from chronic care facilities, four were diabetic, and two had taken oral steroids. Five of the nine patients were treated with the technique of minimal tissue debridement. In brief, the scrotum was bivalved along the median raphe, each scrotal sac was drained, and the testicles were exteriorized. Orchiectomy was performed if the testicles were grossly necrotic. Penrose drains were inserted from each scrotal sac to the counterincision at the level of the internal rings. All of the tissue involved was irrigated with betadine and peroxide, after debridement of the necrotic tissue. Broad-spectrum antibiotics along with daily packing were continued for 4 to 6 weeks; at the end of that time the testicles were returned to the scrotum and the skin was loosely reapproximated. Three of the nine patients were treated with wide debridement of all the soft tissue including the fascia. One of the patients displayed gangrene of the entire abdominal wall; he was not a surgical candidate and died 3 days later. The four patients treated with minimal debridement all obtained successful treatment of their fasciitis. However, one died of complications related to a duodenal ulcer. The mean hospital stay was 45+/-10 days. Two of the three patients treated with wide debridement required plastic reconstruction using a skin-muscle flap of the perineum. The remaining patient treated with wide debridement died of complications related to metastatic renal carcinoma. The mean hospital stay of this group was 62+/-12 days. The specific flora included: Bacteroidis fragilis in 87 per cent, Peptostreptococcus and Streptococcus in 75 per cent, Clostridia group, Escherichia coli, Enterobacter and Pseudomonas in 62 per cent, Klebsiella in 50 per cent, Staphylococcus in 37 per cent, and Proteus in 12 per cent of the patients. In the surgical management of Fournier's gangrene, wide drainage with minimal debridement resulted in similar morbidity and shorter hospital stay when compared with extensive debridement.     

Fournier's gangrene: Can aggressive treatment save life?

Fournier's gangrene (FG) is a rapidly progressive, fulminant infection of the scrotum, perineum and the abdominal wall. FG is caused by synergic aerobic and anaerobic organisms. Modern surgical series report mortality of up to 67% [2, 3]. This originally rare disease has become more frequent. Aggressive treatment including antibiotics, antigangrenous serum, and treatment of all accompanied diseases and disorders can be successful. Treatment also includes debridement and plastic corrections. Authors describe management of 8 patients with FG. Treatment of FG and all accompanied diseases was in all cases successful. Treatment costs of this kind of patients were approximately 20 times higher than treatment of patients with other urologic diseases.     

特发性阴囊坏疽的诊治

目的：探讨特发性阴囊坏疽的诊治方法。方法：回顾分析21例特发性阴囊坏疽患者的临床资料,结果：对21例患者均行早期多切口切开引流和广泛的清创,90．0％的患者行膀胱造口术,生存率为90．5％,结论：早期多切口切开引流,广泛清创,快速纠正休克,及时使用广谱抗素,以及全身支持治疗和必要的重复清创是治疗成功的关键。