共查询到20条相似文献,搜索用时 15 毫秒
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Disseminated superficial actinic porokeratosis in a 40-year-old man is described. The diagnosis was confirmed by histopathology in which the classical cornoid lamella was seen. 相似文献
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A family is analysed in which disseminated superficial actinic porokeratosis (DSAP) occurred in five members. All three children of one generation are affected. Clinical, histopathological and genetic aspects of DSAP are discussed. Disseminated superficial actinic porokeratosis appears to be a clinical variant of porokeratosis of Mibelli. Since DSAP is a genodermatosis inherited as an autosomal dominant it can occur in any geographical location; however excess sunlight can definitely exacerbate the condition. 相似文献
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Disseminated superficial actinic porokeratosis (DSAP) is a chronic disorder of keratinization characterized by numerous papules and plaques distributed over sun-exposed sites. Treatments are poorly standardized and several investigational therapies have demonstrated limited success in treating DSAP. To our knowledge, there have been no systematic reviews of the literature regarding the treatment of this disease. Herein, we review recent studies pertaining to the treatment of DSAP and evaluate the level of evidence for each of these therapeutic modalities. 相似文献
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Helm TN 《Cutis; cutaneous medicine for the practitioner》2001,67(4):286, 296-286, 298
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Disseminated superficial actinic porokeratosis (DSAP) 总被引:1,自引:0,他引:1
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An 81-year-old Finnish female had a 10-month history of a very pruritic eruption. In the clinical examination porokeratosis was suspected and histologically verified with the typical cornoid lamellae. The eruption involved also the unexposed areas of the skin. The patient had always avoided sunshine because it made her feel uncomfortable. The patient's sister, too, had a solitary lesion of porokeratosis. The pathomechanism of DSAP is discussed. 相似文献
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H M Besenhard H C Korting W Stolz O Braun-Falco 《Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete》1988,39(5):286-290
While there have been several reports about the development of malignant neoplasms in porokeratosis of Mibelli and porokeratosis plantaris, palmaris et disseminata, only one case of squamous cell carcinoma in disseminated superficial actinic porokeratosis (DSAP) has been documented. A review is presented of the variants of porokeratosis that have so far been described in the literature as well as the differential diagnosis, genetic aspects and therapy of DSAP. The first case of DSAP with Bowen's disease is presented. 相似文献
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A patient with disseminated superficial actinic porokeratosis (DSAP) presented with unusual exudative hyperkeratotic plaques in addition to lesions more typical of the disease. The plaques were unresponsive to various systemic antibiotics, but responded dramatically to systemic corticosteroid therapy. 相似文献
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Disseminated superficial actinic porokeratosis. Genetic aspects 总被引:3,自引:0,他引:3
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Disseminated superficial actinic porokeratosis is characterized by multiple, brown, annular, keratotic lesions that develop predominantly on the extensor surfaces of the legs and arms during the third and fourth decades of life. No ideal treatment of disseminated superficial actinic porokeratosis has been found. We describe a patient with this condition whose skin lesions responded to topical tacalcitol. 相似文献
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Disseminated superficial actinic porokeratosis (DSAP) is associated with sun exposure and tanning bed usage and has been rarely reported in association with systemic PUVA. We report the first case of DSAP occurring after topical foot PUVA. 相似文献