组织瓣覆盖技术在尿道下裂手术及术后尿瘘修复中的应用

目的探讨组织瓣覆盖技术在尿道下裂手术及尿瘘修复手术的效果。方法1998年3月至2003年5月，73例尿道下裂手术及术后尿瘘修复手术中，采用5种组织瓣覆盖技术覆盖新尿道及尿瘘内口。尿道下裂组45例中采用带蒂背侧皮下组织瓣转移法27例，带蒂鞘膜瓣转移法3例，局部阴囊推进肉膜瓣法15例；尿瘘组28例中采用带蒂背侧皮下组织瓣转移法4例，局部X—V皮瓣法14例，局部U形组织瓣法10例。结果随访3～36个月，尿道下裂组45例术后3例出现尿瘘，尿瘘组28例均未再发尿瘘，成功率95．9％。结论尿道下裂手术及尿瘘修复手术中采用组织瓣多层覆盖技术，可提高手术成功率，降低术后尿瘘发生率。     

Tube-onlay-tube tunica vaginalis flap for proximal primary and reoperative adult hypospadias

PURPOSE: We describe the surgical technique of and report the results in the first 20 patients who underwent combined onlay-tube construction of a tunica vaginalis flap. MATERIALS AND METHODS: We repaired 20 cases of proximal primary (8) and repeat (12), adult hypospadias using a tube-onlay in 4, an onlay-tube in 3, a tube-onlay-tube in 9 and an onlay-tube-onlay in 4. In 15 patients contralateral tunica vaginalis was used as a blanket wrap. Three to 6 months postoperatively after obtaining informed consent retrograde urethrography, cystourethroscopy, uroflowmetry and urethral biopsy were done in 20, 17, 10 and 13 patients, respectively. RESULTS: No fistula or diverticulum developed. Complications occurred in 3 patients (15%), including urethral stricture, meatal stenosis and urethral stricture, and meatal regression and urethral stricture in 1 each. All strictures occurred in the distal urethra in reoperative cases. At long-term followup there was no recurrent stricture or meatal stenosis after internal urethrotomy and dilation. Urethral biopsy in all 13 patients showed a stratified epithelium indistinguishable from native urethra. The reasons for delayed presentation include perceiving hypospadias as a normal variation (paribor or cut by angels), losing hope for a cure after multiple failed repairs, being told by urologists that repair is futile and pressure by wives for cosmetic or fertility reasons. CONCLUSIONS: The place of tunica vaginalis in hypospadias surgery is more than coverage for urethroplasty. It can be successfully used for substitution urethroplasty. As an extension to the principles of the onlay flap and the concept of urethral plate preservation, combined onlay-tube constructions of tunica vaginalis, including a tube-onlay-tube flap, are successfully applicable to proximal hypospadias, especially in reoperative cases. Urothelialization of the tunica vaginalis occurs within months of surgery.     

Use of tunica vaginalis to prevent fistulas in hypospadias surgery

Tunica vaginalis was used to wrap around the neourethra at the time of hypospadias repair. This tunica vaginalis wrap prevented urethrocutaneous fistulas in 20 patients who underwent hypospadias repair. It also was successful when used in conjunction with urethrocutaneous fistula repair in 2 patients.     

Tubularización e incisión de la placa uretral para reparación de hipospadias distal primario en 473 casos: evaluación de los resultados según la cobertura y el tipo de sonda

AimWe have previously employed the tubularized incised plate (TIP) repair technique in distal hypospadias cases with a few modifications because of its excellent cosmetic results. In this study, we aimed to evaluate the effects of spongioplasty and dorsal dartos flaps, in addition to short urethral stents on the outcomes of TIP repair.Materials and methodsOnly distal hypospadias cases were involved in this study. Eligible patients were divided into two groups: group A included patients repaired with both spongioplasty and dorsal dartos flap placement, while group B included patients repaired with dorsal dartos flap placement alone. Group A was further divided into two subgroups according to the type of catheter used (bladder catheter or short urethral stent).ResultsA total of 473 patients were included in this study. There was no statistically significant difference observed in the complication rates between the two groups. In Group A, a bladder catheter was used in 107 patients and a short urethral stent was used in 135 patients. When the results of the two groups were compared, there was no statistically significant difference.ConclusionsSpongioplasty could be combined with dorsal dartos flap placement to reduce the need for dorsal plication rather than to reduce the fistula rate. Short urethral stents can be used safely with no postoperative effects in children who have completed toilet training.     

Outcome of hypospadias fistula repair

Objectives To examine the long-term results of hypospadias fistula repair, the factors involved in recurrence and the outcome in cases where this has occurred. Patients and methods The study comprised 113 children undergoing urethrocutaneous fistula repair between 1984 and 1996. Most of the fistulae were closed in two to three layers, with or without a transpositional skin flap. Tunica vaginalis or a scrotal dartos flap was used in patients with inadequate vascularized tissue adjacent to the fistula. Success rates were calculated for each attempt at fistula repair until the patient was cured. Results The median (range) age at primary fistula repair was 40 (18-169) months and the median follow-up after the most recent repair 7.5 (2.3-17) years. The overall success rate of primary fistula repair was 71%. Fistulae which were >2 mm (11 of 21, 52%) were more likely to recur than were those < or = 2 mm (22 of 92, 24%). Recurrence did not relate to the initial form of hypospadias repair, to the means of skin closure nor, with the exception of multiple lesions, to the location of the fistula. The success rates of subsequent repairs were 70% at the second and 50% at the third, fourth and fifth repairs. One child was cured at the sixth attempt. The use of tunica vaginalis or scrotal dartos as a 'waterproofing' layer was limited to the third or subsequent repairs and was successful in five of six cases. Conclusion A simple layered closure with or with no transpositional skin flap is effective in 71% of repairs. For recurrent fistulae, tissues from an unscarred area (tunica vaginalis or scrotal dartos layer) should be used to cover the fistula.     

The Dartos Flap as an Adjunct in Preventing Urethrocutaneous Fistulas in Repeat Hypospadias Surgery

Purpose

Vascularized flaps for repeat hypospadias repair are often limited. We report our experience with the dartos flap in children undergoing secondary hypospadias and complex urethral repair.

Materials and Methods

The dartos flap is fibroadipose tissue between the scrotal skin and tunica vaginalis layers with its vascular pedicle based at the penoscrotal angle. The flap reaches the distal penile shaft without tension. Eight patients 1 to 17 years old (mean age 6) underwent urethral surgery and an interposed dartos flap procedure in 1994 to 1995.

Results

Of 6 patients cosmesis was excellent in 84 percent, erections were straight in 100 percent, and urinary streams were of good quality and without fistula in 100 percent after repeat hypospadias surgery. Following staged repair for anterior urethral valves a urethrocutaneous fistula developed in 1 patient and following urethral duplication repair results were excellent in 1. Mean followup was 1 year.

Conclusions

The dartos flap is easy to mobilize and it provides excellent coverage for repeat proximal hypospadias surgery, since the dartos remains undisturbed. We endorse its use for complex urethral surgery and believe that the extra layer of closure helps to prevent urethrocutaneous fistulas.     

Tunica vaginalis flap following ‘Tubularised Incised Plate’ urethroplasty to prevent urethrocutaneous fistulaa

Introduction:

Surgery for hypospadias has been continuously evolving, implying thereby that no single technique is perfect and suitable for all types of hypospadias. Snodgrass technique is presently the most common surgical procedure performed for hypospadias.

Materials and Methods:

We analysed the results of tunica vaginalis flap (TVF) as an additional cover to the tubularised incised plate (TIP) repair.

Results:

A total of 35 patients of hypospadias were repaired using TIP urethroplasty and TVF as a second layer. Mean age at the time of presentation was 6.63 ± 3.4 years. Post-operative complications namely wound infection, flap necrosis, scrotal haematoma, scrotal abscess, urethral fistula, meatal stenosis were recorded and analysed during follow-up period. Need for re-do surgery was considered as failure of the operative procedure. Out of 35 patients, 8 (22.85%) patients had proximal penile hypospadias and 27 (77.14%) patients had distal penile hypospadias. Mean post-operative follow-up was 24.53 months. During the follow-up complications noticed included wound infection (n = 2), urethrocutaneous fistula (n = 1) and meatal stenosis (n = 1). Wound infection was managed with appropriate antibiotics as per hospital policy/culture and sensitivity reports. Meatal stenosis responded to bougie dilatation/calibration during follow-up.

Conclusion:

To conclude, TVF as an additional cover is associated with an acceptable complication rate and good cosmetic results if performed with meticulous tissue handlingKEY WORDS: Hypospadias, tunica vaginalis flap, urethrocutaneous fistula     

肉膜蒂阴茎阴囊联合皮瓣治疗重度或复杂性尿道下裂

目的：探讨重度或复杂性尿道下裂新尿道取材途径。方法：在单一皮瓣不够的情况下彩肉膜蒂阴茎阴囊联合皮瓣作新尿道。结果：47例中术后尿瘘2例。尿道狭窄1例。并发症发生率6.4%，结论：重度或复杂性尿道下裂可采用肉膜蒂阴茎阴囊联合皮瓣作新尿道。     

尿道口周蒂阴囊纵隔皮瓣一期修复尿道下裂

目的 探讨应用异位尿道口周肉膜蒂阴囊纵隔皮瓣一期修复尿道下裂的可行性。方法 1998年以来应用上述方法一期修复尿道下裂31例。结果 28例痊愈，2例无尿瘘，1例尿道狭窄，阴茎阴囊角正常，阴茎伸展自如。结论 该皮瓣血运良好，用于一期治疗尿道下裂疗效确切，阴茎、阴囊间无相互牵扯，操作比较简单，值得推广应用。     

睾丸鞘膜瓣在尿道修复中的应用

目的探讨睾丸鞘膜瓣覆盖技术在尿道畸形和尿道瘘修复中的效果。方法2002年起对38例尿道下裂手术和术后尿道瘘,采用睾丸鞘膜下组织蒂鞘膜瓣覆盖修复。结果术后随访半年至1年,除1例尿道上裂术后瘘修复后再次发生尿道瘘外,其余均获成功,未再出现尿道瘘或尿道狭窄,阴茎外观满意,勃起正常。结论采用该方法可有效防止尿瘘再发生,提高手术成功率且易于获取,对睾丸无不良影响。     

Nueva técnica de fijación de dartos en la reparación de hipospadias

ObjectiveThis study investigates the impact of the use of dartos covering to augment the neourethra on functional and cosmetic results. To evaluate a novel technique demonstrating how to fix dartos flap to cover the neourethra as a barrier in hypospadias repair.Patients and methodsThis study comprised 204 male patients with different degree of hypospadias (DPH: 132, coronal hypospadias: 46, MPH: 26). Their ages ranged from 1-23 ys (mean age: 2ys). Penile chordee was in (DPH: 45, coronal hypospadias: 33, MPH: 26). All patients had abnormal downward directed urinary stream. Hypospadias repair was performed by the classic TIP technique in addition to our novel modification of dartos covering. Patients were submitted to 5 years of follow-up including clinical examination of the functional and cosmetic parameters.ResultsSuccess rates were reported in 200 patients, 3 patients had complications with subcoronal urethrocutaneous fistula and one patient with complete repair disruption.ConclusionTriple dartos fixation is a simple technique for all hypospadiologists to minimize urethrocutaneous fistula as common complication of hypospadias repair with good functional and cosmetic results.     

保留尿道板、带蒂鞘膜补片纠治儿童阴茎下弯

目的：探讨中重度尿道下裂合并的阴茎下弯的纠治方法。方法：回顾2008年5月-2009年11月本院对20例合伴中重度阴茎下弯的尿道下裂患儿施行了分期手术,第一期阴茎伸直术采用了保留原位尿道板、转移带蒂睾丸鞘膜补片法。结果：20例均成功实施手术,术后无皮瓣坏死、感染及渗血情况。有14例半年后施行第二期尿道成形术,术中经人工勃起试验评估阴茎弯曲纠正好。结论：保留尿道板、带蒂睾丸鞘膜补片法是一种纠治阴茎下弯的可靠方法,疗效满意。     

The use of free grafts for correcting penile chordee

PURPOSE: Patients with extensive penile chordee may require free graft placement to create a straight phallus. We review our experience with those who underwent primary (no previous surgery) and secondary repair using dermal and tunica vaginalis grafts to correct penile chordee. MATERIALS AND METHODS: Between 1992 and 1998, 28 patients required free graft placement to correct penile chordee. In 8 cases (29%) primary repair was done using tunica vaginalis in 2 and a dermal graft in 6, while in 20 (71%) secondary repair was performed due to recurrent chordee with or without hypospadias. Tunica vaginalis was used in 3 patients and dermal grafts in 17. Grafts were used when straightening did not result from penile shaft degloving, dorsal plication and urethral plate division. Mean followup was 2 years. RESULTS: Residual chordee developed in 1 of 8 patients after primary and in 2 of 20 after secondary repair. Tunica vaginalis grafts had been placed at repair in all patients with residual chordee but there was no recurrent chordee after dermal graft placement. Chordee recurred in 60% of the patients who received a tunica vaginalis graft. CONCLUSIONS: Conventional techniques, such as penile degloving and dorsal plication, may be used to correct penile chordee in most cases, while free grafts are more likely to be required for secondary repair. We believe that dermal grafts result in more successful repair than tunica vaginalis grafts, which seem to be associated with a higher incidence of residual chordee.     

Use of bladder mucosal graft for urethral reconstruction

BACKGROUND: The ideal tissue for complex urethral reconstruction has yet to be determined, especially in patients with deficient preputium. The use of bladder mucosa as a free graft could be an alternative in these problem cases. METHODS: Bladder mucosa graft urethroplasty was performed on 14 patients with penoscrotal or scrotal hypospadias. The mean age of the patients was 18.7 (range 14-23) years. Ten cases were subjected to primary urethral reconstruction while four cases had previous hypospadias repair. RESULTS: Complete urethral replacement by the bladder mucosa tube was performed in six patients. Meatal problems occurred in two (33.33%) patients and proximal fistula formed in one (16.67%) patient. A bladder mucosa graft was combined with preputial or tunica vaginalis grafts distally in eight cases, and one patient in the tunica vaginalis group developed fistula at the anastomosis of the bladder mucosa and tunica vaginalis grafts. The overall complication rate was 28.6%. CONCLUSIONS: Our initial results showed that bladder mucosa grafts can be used successfully for urethral reconstruction especially when combined with preputial or tunica vaginalis grafts distally.     

Tubularized incised-plate urethroplasty for hypospadias reoperation

OBJECTIVE: To review our preliminary results of tubularized incised-plate (TIP) urethroplasty for reoperative hypospadias repair. PATIENTS AND METHODS: The study comprised 15 patients, of whom eight had undergone a previous repair by techniques that included incision into the midline of the urethral plate, while in the remaining seven the midline of the plate had been left undisturbed. The meatus at reoperation was subcoronal or on the distal shaft in all but one boy, who had a midshaft hypospadias. All had previously undergone one attempt at hypospadias repair, except for one patient presenting after two failed 'meatal advancement and glanuloplasty incorporated' procedures. The TIP repair was undertaken as described for primary surgery, except that the dorsal dartos flaps for interposition between the neourethra and skin closure were available less often. RESULTS: TIP resulted in a functional neourethra and a cosmetically normal meatus in 13 of the 15 patients. One boy healed with a slightly rounded meatus and the other had wound dehiscence; fistulae developed in another two boys, giving three patients with complications. The fistulae occurred in boys whose original surgery did not include urethral plate incision, while the dehiscence was in a patient with partial excision of the plate during previous tubularized preputial flap repair. CONCLUSIONS: TIP urethroplasty can potentially be used for hypospadias reoperation. Previous incision of the urethral plate was not a contraindication in these selected cases in which the plate appeared supple. However, TIP repair should be avoided in repeat hypospadias surgery if the plate has been resected or is obviously scarred.     

Standard Snodgrass technique in conjunction with double-layer covering of the neourethra with dorsal dartos flap is the therapy of first choice for hypospadias

PURPOSE: To evaluate the validity of the standard tubularized incised plate (TIP) urethroplasty technique for different kinds of hypospadia. MATERIALS AND METHODS: From June 2002 to December 2003 and from March 2006 to October 2007 38 patients aged 1-22 years (average 7.34) were operated using the concept of TIP urethroplasty. The hypospadiac meatus were subcoronal in 28 patients (73.68%), midshaft in six (15.78%), and penoscrotal in four (10.52%). Standard TIP urethroplasty in conjunction with double-layer covering of the neourethra with dorsal dartos flap were used in the primary cases (28 patients). In the secondary cases (four patients) and in boys who were circumcised before admission (six patients), modified TIP urethroplasty was used. The mean periods of hospitalization and follow-up were 0.92 days and 4.19 months, respectively. RESULTS: No fistulas were observed in boys who underwent primary reconstruction using standard TIP urethroplasty. Fistulas were observed in two patients (5.26%)-one patient with penoscrotal hypospadias who underwent two-stage repair and another who was circumcised before admission. One patient had meatal stenosis at the early postoperative period which was corrected by dilatation of the external meatus at intervals up to 2 months postoperatively. CONCLUSION: Standard TIP urethroplasty with double-layer covering of the neourethra with dorsal subcutaneous tissue is the procedure of choice for treatment of primary cases of distal/midshaft hypospadias. This technique seems suitable for reconstruction of proximal, secondary, and even complicated hypospadias.     

应用阴囊筋膜血管网皮瓣的尿道再修复

目的：探讨阴囊筋膜血管网皮瓣在尿道下裂再修复中的应用。方法：阴囊皮肤存在多源性血供系统，4组血管终末支相互吻合，形成完整的动脉环路在肉膜内走行，通过筋膜层滋养皮肤。基于此项解剖学基础，术中设计不含知名动脉的阴囊筋膜血管网皮瓣，用于修复原已采用阴囊纵隔皮瓣或其他轴型皮瓣进行尿道下裂矫治而失败的病例。结果：本组20例患者，阴茎型5例，阴茎阴囊型8例，阴囊型7例。除1例出现尿瘘，经处理后痊愈，19例尿道重建成功，效果满意。结论：应用阴囊筋膜血管网皮瓣重建尿道是尿道下裂再修复较为理想的方法。     

A modified tubularised incised plate urethroplasty technique and a revised hypospadias algorithm

To simplify and standardize surgical management of hypospadias, a modified tubularised incised plate (TIP) urethroplasty (Snodgrass) technique has been described and a revised hypospadias management algorithm has been formulated. The study aims to evaluate the viability of the described procedure in different types of hypospadias and tests the validity of the algorithm. The modification described is recruitment of penile and glandular skin lateral to the urethral plate to facilitate tubularisation. The algorithm starts with penile degloving with preservation of urethral plate. Snodgrass repair was done in cases with no chordee and where skin chordee resolved by skin take down. Modified Snodgrass repair was done in cases where urethral plate was narrow. Another modification proposed by us is single layer penile skin closure instead of an added dartos flap, which was done in both classical and modified Snodgrass repair. Cases of severe chordee not resolved by skin take down were repaired by transverse preputial island flap (TPIF) and Bracka''s technique. Dorsal plication was not used as an orthoplasty modality. It was possible to repair 68.89% of the cases by Snodgrass repair. These patients either had no chordee or had superficial skin tethering (skin chordee) which resolved on degolving. All these cases were coronal, distal and mid penile hypospadias. Remaining cases were mid, proximal and penoscrotal with true fibrous chordee and were repaired by TPIF or Bracka''s technique. The Snodgrass technique had a fistula rate of 9.67%. Acceptably, low fistula rate and simple execution make the proposed modification of classical Snodgrass repair a viable option. The proposed algorithm proves to be a useful tool for standardised and logical preoperative decision making. It also defines indications of the three techniques vis-à-vis the type of hypospadias.     

带蒂睾丸鞘膜瓣代尿道治疗尿道下裂合并睾丸鞘膜积液(附9例报告)

目的:探讨尿道下裂合并睾丸鞘膜积液的治疗方法。方法:对9例2～12岁尿道下裂合并睾丸鞘膜积液患儿行带蒂睾丸鞘膜瓣代尿道术。结果:①效果满意者7例,均正位开口排尿,切口无感染,术后7～10d出院;②较满意者1例,局部感染,尿道外口狭窄,行尿道扩张后,排尿通畅;③不满意者1例,发生尿瘘,为阴囊型。结论:带蒂睾丸鞘膜瓣代尿道术疗效满意,手术创伤小、取材方便、组织修复迅速,对合并有睾丸鞘膜积液的尿道下裂患者值得推广。     

Tunica vaginalis urethroplasty.

Tunica vaginalis on a vascular pedicle was tubularized and used as a urethra to repair hypospadias in three difficult cases. This is the first report of tunica vaginalis utilized for a urethral reconstruction in humans. This new surgical technique is described.