Pediatric Positron Emission Tomography–Computed Tomography Protocol Considerations

Pediatric body oncology positron emission tomography-computed tomography studies require special considerations for optimal diagnostic performance while limiting radiation exposure to young patients. Differences from routine adult procedures include the patient preparation phase, radiopharmaceutical dose, computed tomography acquisition parameters, and approach to computed tomography contrast materials and imaging sequence. Attention to these differences define the best practice for positron emission tomography-computed tomography examinations of children with cancer contributing to optimal care of these patients.     

Protocol Considerations for Thoracic Positron Emission Tomography–Computed Tomography

The rapid technological advances of positron emission tomography-computed tomography (PET-CT) have introduced many new possibilities and questions as to how best to utilize and perform 2-deoxy-2-[F-18]fluoro-D-glucose (FDG) PET-CT for maximum clinical benefit. The focus of this discussion is the tailoring of PET-CT protocols, emphasizing the incorporation of optimized (diagnostic) CT techniques, for adult thoracic oncologic indications. Many of the protocol strategies described, particularly those involving breath-hold and contrast-enhanced CT, are based on the author's experience in a busy private practice PET-CT center, prior to a recent transition to an academic practice.     

Initial Results with 11C-Acetate Positron Emission Tomography/Computed Tomography (PET/CT) in the Staging of Urinary Bladder Cancer

Purpose  

To investigate the utility of ¹¹C-acetate positron emission tomography/computed tomography (PET/CT) for staging of bladder cancer and response assessment after neoadjuvant chemotherapy.     

Clinical Utility of Positron Emission Tomography/Computed Tomography in Inflammatory Bowel Disease

Purpose  

The clinical utility of positron emission tomography/computed tomography (PET/CT) in comparison to standard workup in patients with known or suspected inflammatory bowel disease (IBD) is unknown.     

胰高血糖素样肽-1受体PET/CT定位诊断胰岛素瘤的技术规范

胰岛素瘤的诊断和手术治疗依赖于准确的影像学检查定位。以胰腺β细胞为靶点的胰高血糖素样肽-1受体(glucagon-like peptide-1 receptor, GLP-1R)是近年来胰岛素瘤影像研究中的亮点, 推荐临床推广使用⁶⁸Ga-exendin-4进行GLP-1R正电子发射断层显像/计算机体层成像(positron emission tomography/computed tomography, PET/CT)来定位诊断胰岛素瘤。本文介绍GLP-1R显像在胰岛素瘤中的应用概况, 并以⁶⁸Ga-exendin-4 GLP-1R PET/CT显像为例, 介绍该技术的操作规范, 以期为临床提供借鉴。     

18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Following Chimeric Antigen Receptor T-cell Therapy in Large B-cell Lymphoma

Molecular Imaging and Biology - 18F-Fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) is a well-established imaging modality to assess responses in patients with...     

Utility of Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Patients with Fever of Unknown Origin Diagnosed as Lymphoma

Objective

To assess the efficacy of fluorine-18 fluorodeoxyglucose positron emission tomography (¹⁸F-FDG PET)/computed tomography (CT) in the diagnosis of patients with fever of unknown origin (FUO), who were finally diagnosed as lymphoma.

Subjects and Methods

A retrospective study was performed in the First Affiliated Hospital, School of Medicine of Zhejiang University, China, from March 2009 to March 2012. The PET/CT images of consecutive patients with FUO were analyzed. Within 1 week of PET/CT scanning, additional histological tests were also performed if clinically needed.

Results

A total of 73 consecutive patients were included. Of these, 34 (47s%) had a PET/CT finding suggestive of the presence of lymphoma and 29 (85s%) had a diagnosis of confirmed lymphoma; 39 (53s%) had a PET/CT result revealing the absence of lymphoma and 4 (10s%) were diagnosed by biopsy as having lymphoma. The most frequent lymphoma diagnosis was peripheral T cell lymphoma (n = 16; 55s%), followed by diffuse large B cell lymphoma (n = 9; 31s%). The accuracy of PET/CT was 88s%.

Conclusion

In this study, PET/CT had high diagnostic accuracy in patients with FUO resulting from lymphoma, which indicated that PET/CT scanning was a valuable diagnostic tool for these groups of patients with FUO.Key Words: Fever of unknown origin, Positron emission tomography, Computed tomography, Diagnosis, Lymphoma     

PET与伽玛PET在癫痫灶定位中的应用

就正电子发射断层成像 (PET)与伽玛PET在癫痫灶定位中的应用作一介绍     

正电子发射计算机断层显像在脑梗死治疗中的应用进展

脑梗死系由各种原因所致的局部脑组织血液供应障碍,导致脑组织缺血缺氧性病变坏死,进而产生临床上对应的神经功能缺失表现。本文对正电子发射计算机断层显像在脑梗死治疗中的应用进行总结。     

Single-photon Emission Tomography/Computed Tomography Delineation of Freiberg Infraction

The role of nuclear medicine diagnostic bone scanning is well established and the influence of coregistration between single-photon emission computed tomography and computed tomography well documented. This case provides an insight into a less frequently encountered pathology in which the combination of single-photon emission computed tomography and computed tomography permitted the differentiation of potential pathology.