基于寻常性银屑病患者报告结局评价量表的研制及其信度和效度评价

目的研制基于寻常性银屑病患者报告以主症为疗效评价指标的临床结局评价量表(寻常性银屑病主症量表),并评价其信度和效度。方法通过文献研究、专家共识、小组反复讨论制定寻常性银屑病主症量表初版,通过进行现场问卷调查进行信度和效度分析。信度分析主要采用克朗巴赫α系数测量内部一致性信度,并采用探索性因子分析方法考评量表的效度,采用PASI分级为效标评价量表的效标关联度。结果发放213份量表,回收率为99.5%,完成率为98.6%。重测信度Spearman平均相关系数0.88(P0.01),内在一致性分析克朗巴赫α系数为0.86(13个条目)、0.87(14个条目);结构效度分析,13个条目的因子分析共提取了2个公因子,累计因子贡献率为51.28%(KMO=0.87,x±s=914.26,P0.001);14个条目的因子分析共提取了4个公因子,累计因子贡献率为70.42%,(KMO=0.75,x±s=334.06,P0.001);效标关联度分析,13个条目的量表与PASI分为轻中重度分级(PAIS7","7≤PASI≤12","PASI12")评分之间的Spearman相关系数为r=0.26,P0.05。结论构建的寻常性银屑病主症量表有14个条目,且具有良好的信度和效度,这可能成为中医药治疗寻常性银屑病诊疗评价的补充工具。     

中文版女性性功能量表在乳腺癌幸存者中应用的信效度评价

目的:评价中文版女性性功能量表在乳腺癌幸存者人群中的信效度。方法:采用中文版女性性功能量表调查2015年3月至2016年3月在上海市某2所三级甲等医院乳腺外科或门诊就诊的乳腺癌幸存者322例,最终纳入分析279例。采用相关分析和极端组检验法进行项目分析;采用Cronbach’sα评价量表内部一致性信度;采用因子分析评价结构效度。结果:中文版女性性功能量表各个条目与其对应维度总分的相关系数为0.728~0.997,维度之间的相关系数为0.514~0.925,各维度与总分的相关系数为0.767~0.873,P均小于0.01;极端组检验法结果显示两组之间的差异具有统计学意义;量表总体内部一致性信度Cronbach’sα系数为0.976,各维度的内部一致性信度Cronbach’sα系数为0.540~0.987;因子分析共提取3个因子,累计方差贡献率为67.669%。结论:中文版FSFI在乳腺癌人群中经检验信效度良好,可作为相关研究的测量工具评价乳腺癌幸存者的性生活状态。     

护士性健康照护素养量表的编制与信效度检验

目的:编制评价我国护士性健康照护素养量表,并检验其信度与效度。方法:以简单随机抽样对258名护士进行问卷调查,并采用探索性因子分析与验证性因素以简单随机抽样分析对量表进行检验。结果:性健康照护素养量表共17个条目,经探索性因子分析产生3个公因子(因子1为性健康照护知识;因子2为性健康照护态度;因子3为性健康照护效能),累计贡献率为55.334%。各条目内容效度指数(ICVI)为0.896~0.922,量表内容效度指数(S-CVI)为0.920;而验证性因子分析表明(χ~2=163.218,df=115,P0.001,GFI=0.948,AGFI=0.988,NFI=0.916,NNFI=0.925,CFI=0.941,RFI=0.903)。总量表的Cronbach’sα系数为0.862,重测信度为0.888。结论:护士性健康照护素养量表具有较好的信、效度,可做为评价护士性健康照护素养的现状。     

青少年女性性自我效能问卷的编制与信效度检验

目的:编制适用于我国青少年女性性自我效能的调查问卷,以供评价青少年女性性健康行为水平的工具。方法:通过访谈法、专家咨询法与文献法的基础上编制了青少年女性性自我效能的原始问卷,并运用调查法对511名青少年女性进行测试,并用SPSS分析软件进行信度、效度检验。结果:平均内容效度比(CVI)为0.902,探索分析性因子分析问卷得到15个条目,形成2个因子,即预防措施、拒绝自我效能,KMO值为0.824,χ~2=1383.05,P=0.000,各因子载荷范围为0.567~0.743;问卷总的内部一致性系数Cronbach’sα为0.884,2个维度的内部一致性系数Cronbach’sα系数范围为0.865~0.902;重测信度Cronbach’sα为0.842。结论:青少年女性性自我效能问卷具有较好的信、效度,可用于评价青少年女性性健康行为的现状。     

青少年女性性健康促进量表的构建与信效度研究

目的:依计划行为理论为基础,构建性健康促进量表(SHPS),并检验量表的信度与效度。方法:通过性健康促进量表、青少年性与生殖健康文献分析、深度访谈、以及专家咨询,形成SHPS预实验量表,对183名青少女进行问卷调查,对预实验量表进行条目分析、探索性因子分析归纳维度,形成正式量表。正式问卷调查,采分层集束比例抽样,以388名青少女[平均年龄为(18.15±0.39)岁]为对象,分析及建构量表的信效度。结果:SHPS通过探索性因子分析,由22个条目组成,包括性健康知识、性生理需求、避孕态度、艾滋病认知等4个公因子,累积方差贡献率为67.982%;总体内容效度指数为0.926;总量表的Cronbach’sα系数为0.904,重测信度为0.882;而验证性因子分析(χ2/df=2.562,P<0.001,GFI=0.962,RMSEA=0.048,AGFI=0.950,NFI=0.958,CFI=0.934),具有较好的适配度。结论:青少女性健康促进量表具有较好的信度与效度,为评价国内青少女性与生殖健康现状提供科学依据。     

Scalpdex中文版在头皮银屑病患者应用中的信度和效度评价

目的测评Scalpdex中文版应用在头皮银屑病患者中的信度和效度。方法调查了272例头皮银屑病的门诊患者和住院患者。使用克朗巴赫系数、分半信度和重测信度检验Scalpdex中文版的信度,使用内容效度、聚合效度、判别效度、区分效度和结构效度考察其效度。结果 Scalpdex中文版的克朗巴赫系数范围是0.82～0.91,分半信度为0.81～0.88,重测信度为0.76～0.90。除有2个条目与所属维度相关系数小于0.4外,其余条目与所属维度的相关系数均大于0.4。Scalpdex中文版能区分患者自评不同病情程度和不同病程的生命质量。探索性因子分析共提取3个公因子,所得的因子累计贡献率均高于61.55%,因子结构与源量表预设时的结构能部分吻合。结论 Scalpdex中文版在头皮银屑病患者中具有良好的信度和效度,可用于中国文化背景下的头皮银屑病的生命质量评估及临床决策的研究。但本次研究也发现个别条目还需要进一步调适、修订和验证,使得相关概念呈现得更加清晰和完整。     

敏感性皮肤问卷的编制及其与鲍曼敏感性皮肤问卷的信度和效度比较

目的编制一套适用于国人敏感性皮肤的问卷,为敏感性皮肤的诊断提供简便有效的方法。方法基于鲍曼敏感性皮肤问卷,采用专家法、统计学方法编制本院敏感性皮肤问卷(华西问卷),采用随机偶遇法对志愿者进行华西问卷、鲍曼问卷调查,比较两套问卷的信度和效度。结果共纳入699名志愿者,筛选修订问卷最终形成12个条目的华西问卷。华西问卷与鲍曼问卷的内部一致性Cronbach'sα值分别为0.802和0.823,重测信度分别为0.906和0.796。进行最大变异方差正交旋转,提取特征值大于1的因子,华西问卷的4个共同因子累计解释变异量为60.78%,鲍曼问卷的5个共同因子累计解释变异量为52.25%。结论华西问卷的信度和效度均优于鲍曼问卷,更适用于国人敏感性皮肤筛查。     

病耻感量表在男性不育症患者中的信效度检验

目的 检验病耻感量表在我国男性不育症患者中的信效度。方法 采用方便取样法,选取2021年12月15日至2022年2月15日在北京市某三甲医院生殖医学中心诊治的338例男性不育症患者作为研究对象。采用基本情况调查表、修订后的病耻感量表及生育生活质量量表进行研究调查。结果 本研究最终形成了包含4个公因子和22个条目的病耻感量表。修订后量表总的Cronbach′s α系数为0.974,折半信度为0.924。方差累计贡献率为78.9%,量表结构效度、聚敛效度、组合信度与区分效度经检验结果均较好,且与生育生活质量有较好的效标关联效度。结论 修订后的病耻感量表信效度良好,可用于我国男性不育症患者病耻感的评估。     

痤疮患者相关知识问卷的信效度研究

目的研究能够客观评价痤疮患者相关知识的问卷,并进行信效度检验。方法通过回顾相关文献回顾、半结构化访谈、专家访谈和专家评议法,形成初始问卷。选取403例痤疮患者进行调查。对问卷信效度进行评价,形成问卷终稿。结果最终形成的痤疮相关知识问卷包括5个维度、24个条目。通过探索性因子分析提取5个公因子。累计方差贡献率为53.907%,问卷内容效度为0.961,Cronbach’sα系数为0.829,重测信度0.897。结论该问卷具有良好的信效度,可作为评价痤疮患者痤疮相关知识了解程度的工具。     

中国银屑病患者生活质量量表的编制与考评

目的:编制银屑病患者生活质量量表(psoriasis quality of life scale,PQOLS),并验证该量表信度和效度。方法:根据WHO对生活质量的定义提出理论框架,通过文献回顾和专家咨询的方式编制PQOLS测试版。然后采用初始量表测定银屑病患者的生活质量,根据结果对条目筛选,形成PQOLS的正式版。结果:通过文献回顾和专家咨询建立包含40个条目的备选条目池。通过条目筛选,最终形成了含22个条目的PQOLS,包括疾病、心理、生理、社会4个维度。对136例患者进行测试结果表明:量表各维度及整个量表的Cronbachα均0.8,Sperman-Brown系数均0.7;因子分析发现单因素能够代表量表的大多数因子;PQOLS与皮肤病生活质量指数(DLQI)的Pearson相关系数为0.821;PQOLS总分与银屑病皮损面积和严重程度指数(PASI)值的相关系数为0.506,生活质量与病情严重度呈显著负相关。结论:编制的PQOLS具有较好的信度、效度,适用于银屑病患者生活质量的测评。     

Development and validation of a questionnaire measuring quality of life in primary caregivers of children with atopic dermatitis (QPCAD)

Background  Disease-specific health-related quality of life (HRQoL) instruments for primary caregivers of children with atopic dermatitis are useful in evaluating the efficacy of treatment in clinical practice and study. However, no such scale has been available in Japan.
Objectives  To develop and validate a self-administered instrument specifically designed to measure quality of life in primary caregivers of children with atopic dermatitis (QPCAD).
Methods  This study consisted of three successive phases: the item generation phase, pilot test phase and validation phase. In the item generation phase, questionnaire items were derived from 33 qualitative interviews with primary caregivers. In the pilot test phase, the face and content validity of the preliminary scale were assessed ( n  = 33). In the validation phase, the questionnaire was finalized and assessed in terms of statistical performance ( n  = 416).
Results  The QPCAD included 19 items in the following categories: 'exhaustion', 'worry about atopic dermatitis', 'family cooperation' and 'achievement'. The reliability of internal consistency was fair (Cronbach's alpha coefficients 0·66–0·87). The QPCAD subscales and total score were significantly correlated with psychological health, physical health, anxiety, depression and severity score, with mild to moderate correlation coefficients. Test–retest reliability and responsiveness to change in severity were also satisfactory.
Conclusions  The QPCAD is an appropriate tool for assessing HRQoL of primary caregivers of children with atopic dermatitis in clinical practice and clinical trials.     

Measuring health-related quality of life in patients with mild to moderate eczema and psoriasis: clinical validity, reliability and sensitivity to change of the DLQI. The Cavide Research Group

The aim of this study was to assess the feasibility, validity, reliability and sensitivity to change of a Spanish version of the Dermatology Life Quality Index (DLQI) in patients with mild to moderate eczema and psoriasis who were treated with topical corticosteroids. The final study sample comprised 237 patients (48% eczema). Discriminant validity was tested by comparing patients' scores with those of a random sample of the general population (n = 100), and convergent validity by analysing correlations between DLQI scores, measures of clinical severity, and domain scores on the Nottingham Health Profile (NHP). Internal consistency and test-retest reliability were tested in clinically stable patients (n = 94), and responsiveness in a clinically unstable group (n = 143) initiating treatment with topical corticosteroids. Patient scores were significantly higher than general population scores (4.3 vs. 0. 27, P < 0.001). Correlations with NHP domains ranged from 0.12 to 0. 32, and there was significant correlation with clinical measures (r = 0.26, P < 0.001). Reliability was good (Cronbach's alpha = 0.83; intraclass correlation coefficient = 0.88), and the instrument proved responsive to change (effect size for the total group of de novo patients = 0.70), though the great majority of changes occurred in items 1 and 2. The NHP Emotional Reactions and Mobility domains were more responsive than some DLQI domains. In clinical trials of treatments for mild to moderate eczema and psoriasis, it is likely that only items 1 and 2 of the DLQI will be needed, and it is probably advisable to include generic instruments alongside the DLQI.     

Validity and reliability of the Turkish version of The Pressure Injury Prevention Knowledge Questionnaire(PIPK)

AimThis study aimed to evaluate the validity and reliability of the Turkish version of the Pressure Injury Prevention Knowledge Questionnaire (PIPK).MethodA methodological study design was used. The instrument was translated into Turkish and back-translated into English. After evaluating the language equivalence and content validity of the scale, test-retest reliability, internal consistency and construct validity were examined. The research was conducted with a total of 324 nurses working in a state hospital and two private hospitals who volunteered to participate in the research. Number, percentage distributions, intraclass correlation coefficient (ICC), Kappa coefficient test, Man Whitney U test and Rasch analysis were used to evaluate the data.ResultsContent validity was evaluated by 11 experts in wound care and the CVI(content validity index was found 0.90. The correlation coefficient between the groups was found to be ICC 0.979 in the Kappa coefficient test performed for the reliability analysis. When the in- and out-of-fit difficulty index values of the scale were examined, it was found that the averages of these values varied between “0.72” and “1.38” values.ConclusionsThe Pressure Injury Prevention Knowledge Questionnaire (PIPK) was found to be a valid and reliable tool for intercultural studies revealing the nursing knowledge of prevention on PIs. It is recommended to conduct studies that test the validity and reliability of the scale in different samples.     

Validity and reliability of the Turkish version of the pressure injury knowledge assessment tool 2.0

AimThe aim of this study was to develop a Turkish version of the Pressure Ulcer Knowledge Assessment Tool 2.0 (PUKAT 2.0) and determine its validity and reliability.Materials and MethodsThis was a cross-cultural adaptation and validation study. The study sample included a total of 451 participants (232 nurses and 219 nursing students). The validity of the Turkish version of the PUKAT 2.0 was evaluated with linguistic validity, content validity, item validity (item difficulty, discriminating index), and construct validity (known-groups technique) analyses. The reliability of the tool was evaluated by conducting a test–retest analysis.ResultsContent validity index (CVI) for the items (Item-CVI) ranged from 0.83 to 1.00 and the CVI for the scale (Scale-CVI) was 0.95. The difficulty index for 21 items ranged from 0.10 to 0.63. Four items were found to be too difficult. Item discriminating index values ranged from 0.00 to 0.61. The overall intraclass correlation coefficient (ICC) was found to be 0.80.ConclusionThe Turkish version of the Pressure Injury Knowledge Assessment Tool 2.0 (PIKAT 2.0-Tr) is supported by acceptable psychometric properties and can be used to evaluate the knowledge of nurses and nursing students in Turkey about the prevention of PI.     

中文版慢性荨麻疹生活质量问卷（CU-Q2oL）信效度验证

【摘要】 目的 检验中文版慢性荨麻疹生活质量问卷（CU-Q2oL）的信效度。方法 翻译英文原版CU-Q2oL以及回译和文化调试，确定中文版CU-Q2oL的条目。2019年1 - 12月对北京大学第一医院皮肤性病科就诊的195例慢性自发性荨麻疹伴或不伴慢性诱导性荨麻疹患者每2周进行1次随访，随访时填写CU-Q2oL、皮肤病生活质量指数问卷（DLQI）以及1周疾病活动度问卷评分（UAS7），共随访2次。每次随访后，医生依据患者病情为每例患者调整治疗方案。通过探索性因子分析，提取问卷因子数目，并通过分析CU-Q2oL与DLQI、UAS7的相关性判断聚合效度，通过计算Cronbach α系数检测CU-Q2oL的内在一致性信度；通过分析UAS7的变化量与CU-Q2oL评分变化量的相关系数判断CU-Q2oL的敏感度。结果 自中文版CU-Q2oL问卷中提取出4个因子，分别为“症状”、“日常功能活动”、“睡眠问题”及“限制”因子，共23个条目，累计方差贡献率为74.011%。CU-Q2oL所有条目的Cronbach α系数为0.961，4个因子Cronbach α系数为0.804 ~ 0.933，提示极好的内部一致性。CU-Q2oL问卷总分和DLQI评分、UAS7分别呈中度相关，相关系数分别为0.437、0.560（均P＜0.01）。71例患者参与第2次随访，CU-Q2oL问卷总分变化量与UAS7评分变化量呈中度相关，相关系数为0.392（P＜0.01）。结论 中文版CU-Q2oL具有极好的内部一致性信度和良好的信效度，可用于评估我国慢性自发性荨麻疹患者的生活质量。     

Reliability and validity of the Arabic version of "dermatitis family impact" questionnaire in children with atopic dermatitis

The aim of this study was to develop an Arabic version of the original English version of Dermatitis Family Impact (DFI) questionnaire and to evaluate its reliability and validity among Saudi families having children with atopic dermatitis (AD). Participants were 379 families of affected pediatric patients with AD diagnosed by consultant dermatologists in addition to a control group of 124 parents, who denied the presence of any dermatologic disorders in their children. To develop an Arabic version of the DFI, rigorous international guidelines for translation-back-translation were followed. In addition, reliability and validity were evaluated by calculating Cronbach's alpha and correlation coefficients. Construct validity was assessed by comparing individual items and total scores among various case severity groups and controls. Cronbach's alpha (=0.90) was acceptable. The inter-item, item-total score and item-severity correlations ranged from moderate to high and were statistically significant (～0.60, P-values <0.001). The distribution of item responses evaluated by the ceiling and floor effects showed appropriate proportions and a good discrimination between cases and controls and between severity groups. The DFI scale scores (Mean ± SD) were 3.0 ± 1.50 for control, 9.6 ± 2.88 for mild, 14.67 ± 2.27 for moderate and 18.14 ± 2.0 for severe cases (P < 0.001). The results of this study showed that our translated Arabic version of the DFI is an efficient tool in terms of its reliability and validity for the measurement of the disease impact in families with AD.     

Assessing psychological distress in patients with skin diseases: reliability, validity and factor structure of the GHQ-12

OBJECTIVE: We studied reliability, validity and factor structure of the 12-item General Health Questionnaire (GHQ-12) in dermatological patients. METHOD: Subjects attending a dermatological outpatient clinic were administered the GHQ-12 and the Skindex-29. A random subsample was mailed another copy of the questionnaires to be completed within 1 week. RESULTS: A total of 2,579 subjects completed the GHQ-12. The internal consistency of the GHQ-12 was high (Cronbach's alpha = 0.88). Test-retest reliability on 137 subjects was also fairly satisfactory (intraclass correlation coefficient = 0.72), notwithstanding a re-test artefact probably related to reassurance from the physician. Evidence of construct validity was provided by the pattern of correlation between scores on the GHQ-12 and on the scales of Skindex-29, which were as hypothesized. Also, GHQ-12 scores of patients in different clinical groups varied as hypothesized, with patients affected by inflammatory skin diseases scoring significantly higher than patients with isolated skin lesions. We obtained both a two-factor and a three-factor solution: the latter seemed theoretically more appropriate, although the first may have practical advantages. A 'social dysfunction' factor emerged in both analyses, while the other items loaded on a 'general dysphoria' factor or on two separate factors interpreted as 'anxiety' and 'loss of self-esteem'. CONCLUSIONS: The GHQ-12 is a reliable and valid instrument with a factor structure that is quite stable across different samples as well as across diverse cultures. Its brevity and easiness of completion make it a useful tool to assess psychological distress in dermatological patients.     

Development and validation of the incontinence associated dermatitis knowledge,attitude and practice questionnaire

AimThis study aimed to develop and test the validity and reliability of the Knowledge, Attitudes and Practices of Incontinence-associated Dermatitis Questionnaire (KAP-IAD-Q) for Nurses.MethodsA psychometric validation design was employed. Phase I of the study entailed the development of items through an extensive literature review and a double Delphi procedure with 11 experts specialised in wound, ostomy and continence to examine content validity of the KAP-IAD-Q. Phase II involved administering the KAP-IAD-Q to a convenience sample of 263 Registered Nurses from a public hospital in Singapore to evaluate its construct validity, internal consistency and test-retest reliability.ResultsThe instrument showed acceptable content validity (S-CVI = 0.85). Exploratory factor analysis showed all 22 items demonstrated strong factor loadings >0.4 and the four factors KAP-IAD-Q explained 58.1% of total variance. The four factors were☹1) knowledge om IAD aetiology and identification, (2) knowledge on IAD risk factors; (3) attitudes, and (4) practices. The overall internal consistency was excellent (Cronbach's α = 0.913). The KAP-IAD-Q showed good overall test-retest reliability as well (ICC = 0.89 (95% CI 0.69–0.96, p < 0.001).ConclusionThe KAP-IAD-Q demonstrated good psychometric properties and is effective in measuring levels of IAD-related KAP among nurses. Further confirmation of the proposed factor structure is recommended. Future research should explore determinants of nurses’ KAP and associations between IAD knowledge, attitudes and practices.