The chick chorioallantoic membrane as test system for biocompatible materials

Biologic and non-biologic materials clinically used as hemostyptica, as vascular prostheses, or as temporary skin substitutes were implanted to the chick chorioallantoic membrane (CAM) during days 9-14 of incubation. The histological study revealed an intact CAM after application of cellulose gauze (Tabotamp). The fibrin tissue adhesive (Tissucol), the collagen sponge (Tachotop), or the gelatin sponge (Gelfoam) induced different amounts of connective tissue. Some fibroblasts were about to grow into the fibrin adhesive. Fibroblasts and capillaries filled the interstices of the collagen sponge poorly, and in the case of the gelatin sponge markedly. Neutrophils and giant cells of the foreign body type occurred more often in the gelatin sponge than in the collagen sponge. With regard to the non-biologic materials, expanded polytetrafluorethylene induced squamous metaplasia of the chorionic epithelium. Dacron caused ulceration with the onset of connective tissue ingrowth, based on a reaction of giant cells of the foreign body type. Polyurethane foam (SYSpur-derm) showed bleeding into the implant due to spikes of the material. Eosinophilic granulocytes were absent in all materials studied. The results are related to different clinical findings. The correlation allows consideration of the CAM as an in vivo model in screening materials for their biocompatibility and their connective tissue reaction.     

腹腔纱布异物CT表现及误诊分析

目的：总结腹腔纱布异物的CT表现特征,分析误诊原因。方法回顾性分析3例经手术病理学检查证实的腹腔纱布异物患者的CT检查结果及临床资料。结果腹腔纱布异物在CT平扫时早期因气体较多而表现为蜂窝状肿块,后期表现为软组织密度肿块,中心密度低于边缘,增强扫描均表现为包膜明显强化而内部无强化。结论腹腔纱布异物在CT增强检查中有一定的特征性表现,综合分析患者CT检查特征表现和临床手术史,能减少误诊的发生。     

国产高膨胀性海绵用于鼻腔填塞的临床观察

目的:比较两种鼻腔填塞材料的疗效,选择理想的鼻腔填塞物。方法:将324例鼻出血及鼻腔鼻窦术后患者分为凡士林纱条填塞组(A组)、国产高膨胀性海绵填塞组(B组)。结果:两组在止鼻出血方面疗效无显著性差异,但在鼻腔填塞后头鼻胀痛、取出填塞物后渗血量及粘膜情况有显著性差异(P<0·01)。结果:高膨胀性海绵是较理想的鼻腔填塞材料。     

生物止血材料在妇产科手术中的应用

背景：良好的生物敷料或纱布可直接促进凝血过程,不仅可用于广泛渗血创面,且在一些常用的妇产科手术中能有效降低渗血率。目的：评价不同生物止血敷料及纱布的材料学性能及应用于妇产科切口的生物相容性,寻找符合不同切口创面需要的止血材料。方法：采用电子检索的方式,在万方数据库（http：//www.wanfangdata.com.cn/）中检索1999-01/2011-04有关妇产科生物止血材料应用的研究文章,关键词为＂妇产科,生物材料,止血敷料,纱布,胶原/壳聚糖＂,排除重复研究、普通综述或Meta分析类文章,筛选纳入30篇文献进行评价。结果与结论：近几年国内外生物医用可吸收止血材料主要包括纤维蛋白胶、壳聚糖、明胶海绵、氰基丙烯酸酯类组织胶、氧化纤维素和氧化再生纤维素等。各种止血性伤口急救材料都有各自的特点,但在妇产科应用的选择上,应考虑多方面因素,包括手术部位、出血部位、切口形态大小、不同渗/出血情况的填塞要求、不同止血材料的自身性能及与机体的相容性等。但因目前尚无完全符合理想标准的材料,因此开发新的快速止血和与宿主相容性良好的止血材料及复合材料势在必行。     

Two foreign body reactions caused by suture materials: mammograms mimic cancer as a spiculated lesion

A spiculated breast lesion on mammogram is highly suggestive of malignancy. However, it can be seen on rare occasions in benign conditions including foreign body associated granuloma. We describe two foreign body reactions in the breast caused by suture materials and describe the clinical, radiological and pathological features.     

Sonographic findings of intraabdominal foreign bodies due to retained gauze

The ultrasonic images obtained in 2 patients with retained gauze in the abdomen are presented. Identification of a cystic mass with highly irregular internal echoes in patients with previous laparotomy should alert the radiologist to the possibility of foreign body retention.     

医用止血材料用于防治乳腺癌术后皮下积液的临床分析

目的观察医用即溶止血纱布联合纤丝速即纱对乳腺癌改良根治术后引流量及皮瓣愈合的影响。方法选择北京市朝阳区桓兴肿瘤医院2015年8月至2016年8月收治的适合行乳腺癌改良根治术的患者共80例,按照随机数字表法将80例分为研究组(40例)和对照组(40例)。研究组患者术中于手术创面联合应用两种止血材料(医用即溶止血纱布联合纤丝速即纱);对照组除术中未使用医用止血材料外,其余处理同研究组。比较两组患者术后1~5天总引流量及引流管拔除时间。结果两组患者的年龄、体质量指数、影响积液产生等指标比较差异均无统计学意义(P均>0.05)。研究组总引流量为(289.23±5.36)ml,对照组为(492.15±8.56)ml,两组比较差异有统计学意义(t=8.543,P<0.05)。研究组引流管拔除时间为(6.24±1.23)d,对照组为(10.12±2.21)d,两组比较差异有统计学意义(t=6.203,P<0.05)。结论应用医用即溶止血纱布联合纤丝速即纱对行乳腺癌改良根治术的患者除有止血功能外,可明显减少术后皮下积液。     

成纤维细胞生长因子生物蛋白海绵对创伤性溃疡修复的作用

背景成纤维细胞生长因子生物蛋白海绵对创伤性溃疡修复的作用已经受到关注.目的观察成纤维细胞生长因子生物蛋白海绵对创伤性溃疡的修复作用及可能发生的不良反应.设计分组对比观察.单位暨南大学医学院生理教研室.对象选择2004-03/05暨南大学第一附属医院收治的皮肤创伤性溃疡患者40例,排除糖尿病及全身感染者,创伤性溃疡均位于小腿.随机分为试验组20例,对照组20例.干预措施试验组20例用无菌成纤维细胞生长因子生物蛋白海绵,对照组20例用无菌凡士林油纱布.更换敷料1次/d,至创面愈合止.全身和局部均不使用影响创面生长的药品.于换药1,2,3周对创面愈合情况进行评估(创面分泌物分为无、少量、中量及多量;创面边缘反应分为无、轻度、中度及重度)记录创面愈合后的色素沉着及瘢痕情况.主要观察指标两组患者溃疡愈合时间、创面愈合过程及不良反应.结果两组共40例患者均进入结果分析.①两组患者治疗后创面愈合情况试验组3周内愈合率显著高于对照组[95%(19/20),55%(11/20),X2=8.533,P＜0.05]试验组创面分泌物及创周炎性反应明显轻于对照组创面;两组创面均未发现明显不良反应及瘢痕.结论成纤维细胞生长因子生物蛋白海绵可促进创伤性溃疡面愈合,缩短愈合时间,且无瘢痕及明显不良反应,是一种安全、方便、无刺激的理想敷料.     

术后不同鼻腔填塞物不适感的原因分析与护理

目的:通过传统的碘仿加凡士林纱条与高膨胀海绵在鼻内窥镜术后填塞反应的比较,探讨影响患者舒适感的原因及护理对策。方法:随机将鼻内窥镜手术的96例患者分成两组,在术后根据需要分别放置凡士林纱条和高膨胀海绵,观察患者的反应,进行对比分析,并对症护理。结果:高膨胀海绵组患者填塞反应轻,凡士林纱条填塞组反应重,通过对不舒适进行护理,可减轻患者症状。结论:高膨胀海绵与传统材料对比有明显优越性,降低了护士对患者个体护理时数,但适应症仍有限,故传统填塞方法仍需采用,术后护理是减少患者痛苦,减轻不舒适感的重要环节。     

男性乳腺癌超声影像特征分析

目的 总结分析男性乳腺癌的超声特征,分析脂肪层厚度与乳腺癌发生的关系.方法 对患乳腺癌的男性患者进行详细超声检查,检查部位包括双乳、腺体周围淋巴引流区及胸壁(范围为双侧腋中线间锁骨上区至肋弓),记录其声像特征,测量乳腺癌患者的胸壁及脂肪层厚度并与正常体质量[(身高cm- 100)×0.9为标准体质量(kg),正负10％为正常体质量]健康体检者进行对比.结果 ①男性乳腺癌超声影像特征多见:边缘毛刺、内部回声不均、钙化、后方声衰、彩色多普勒血流丰富等.②肿块最大径、血流分级与淋巴结转移有关,肿块越大、血流分级越高,转移癌的发生率越高.肿块的边界、内部回声、有无钙化及后方声衰淋巴结转移者与无淋巴结转移者差异无统计学意义(P＞0.05).③乳腺癌组的胸壁及胸壁脂肪层厚度与健康对照组不同,胸壁厚度分别为(1.37±0.12)cm vs(1.31±0.08)cm(P＜0.05),胸壁脂肪层厚度为(0.89±0.09) cmvs (0.86±0.06) cm(P＜0.05).结论 男性乳腺癌超声特征典型,发生淋巴结转移较早,乳腺癌发生与脂肪密切相关,有必要进一步总结乳腺癌发生概率与脂肪层厚度的关系,为男性乳腺癌的发生提供预警和风险评估.     

Detection of retained surgical sponge by transthoracic and transesophageal echocardiography

We describe an unusual case of extracardiac mass in a patient who was assymptomatic and submitted to an open-chest coronary artery bypass operation 5 years previously. Transthoracic and transesophageal echocardiography revealed a rounded mass compressing the right atrium with a thick contour surrounding a heterogeneous center, suggestive of foreign body. Magnetic resonance imaging identified the mass as a pericardial cyst. Operation revealed a fibrinous cyst encapsulating a sponge. This case illustrates the central role of echocardiography for the diagnosis and treatment of patients with suspected retained surgical sponges.     

2种材料填塞鼻腔治疗鼻衄的疗效观察

目的探讨2种材料填塞鼻腔治疗鼻衄的疗效。方法总结2004年1月-2006年12月本院五官科使用2种材料填塞鼻腔治疗鼻衄的情况。抽取95例使用凡士林纱条来填塞鼻腔治疗鼻衄作为A组，并对应地抽取95例使用Mevocel高膨胀海绵来填塞鼻腔治疗鼻衄作为B组，综合观察疗效。结果2组病人止血效果、不适感（头痛、头晕、鼻部胀痛）、心理恐惧、取出后不易再出血等情况比较，经统计学分析，均p〈0．01，差异有统计学意义。结论使用Mevocel高膨胀海绵来填塞鼻腔治疗鼻衄，可减少病人并发症（头痛、头晕、鼻部胀痛、呼吸及吞咽困难、睡眠障碍）、心理恐惧感的发生，且止血效果好、快，取出后不易再出血。     

隆乳术引起凝胶肉芽肿1例并文献复习

目的：阐述亲水性聚丙烯酰胺凝胶（HPAMG）注射隆乳术引起凝胶肉芽肿的病理改变。方法：对1例HPAMG注射隆乳术后引起肿块的活检标本进行肉眼和组织形态学观察。结果：主要病理改变为异物肉芽肿及由异物巨细胞和胶原纤维包绕的大小不等的囊腔，囊内充满不规则蓝染异物，伴有脂肪和肌肉凝固性坏死。结论：某些HPAMG可能对机体组织有一定毒性作用。     

乳腺癌X线特征与Ki-67表达的相关性研究

目的分析乳腺癌X线特征与Ki-67表达的相关性。方法分析经乳腺X线摄影以及手术病理证实的76例乳腺癌患者,将X线所见按肿块(大小、边缘、形态)和钙化(分布、形态)情况进行描述,并与Ki-67的表达进行对照,分析其相关性。结果乳腺癌Ki-67阳性表达的X线特征为肿块直径>2.0cm、类圆形肿块、杆状钙化。结论乳腺癌Ki-67的表达与肿块大小、肿块形态、钙化形态有显著的相关性,根据X线特征可大概推测Ki-67的表达情况。     

Squamous cell carcinoma with sarcomatous stroma of the mesopharynx

A case of squamous cell carcinoma with sarcomatous stroma of the mesopharynx is presented. The patient was a 62-year-old man who complained of a foreign body sensation. Endoscopic examination revealed a large pedunculated mass arising from the posterior wall of the mesopharynx. The lesion was surgically resected, using a cutting snare by the endo-oral approach, and was completely removed. A diagnosis of squamous cell carcinoma with sarcomatous stroma was made histopathologically. The clinicopathological features of this case are described and compared with those of previously reported cases.     

鼻腔肿瘤术后应用膨胀海绵填塞术腔的护理干预分析

目的探讨鼻腔肿瘤患者鼻内镜术后应用膨胀海绵填塞鼻腔的效果并分析相关护理干预措施。方法将50例手术患者随机均分为实验组和对照组,实验组术后以膨胀海绵填塞鼻腔,对照组术后以凡士林纱条填塞鼻腔,2组均密切观察病情变化并加强心理护理、生活护理、口腔护理、饮食指导等,观察2组患者术后鼻部胀痛、鼻腔出血量、睡眠时间、进食及住院天数改善等情况。结果实验组患者术后疼痛、出血、睡眠及食欲情况均显著好于对照组(均P相似文献   

体内异物的超声检查与定位诊断

本文报告4例体内异物的超声图像表现及特征，其中2例为术中遗留纱布里弧形和带状强回声，后方伴声影。1例腹后壁自制猎枪子弹，1例胸腔玻璃碎片分别呈圆点状和带状强回声，后方伴随多次反射。常规经体表超产检查、术前超声引导下穿刺活检、术中超声检查具有人法简便、灵敏度高、直观效果等优点为体内异物的定位诊断．提供了又一重要的影像学检查手段。     

夹层明胶海绵油纱条在鼻内窥镜下填塞鼻腔止血的临床应用价值

目的探讨将夹层明胶海绵油纱条在鼻内窥镜术后填塞止血的应用效果。方法2003年1月至2009年4月因慢性鼻窦炎,鼻息肉,进行鼻内窥镜手术的病人400例。用明胶海绵与油纱条共同填塞的夹层明胶海绵作为填塞材料,与金霉素普通纱条填塞后的止血效果、鼻腔反应进行比较。结果用夹层明胶海绵填塞止血的效果好,与普通纱条相比,夹层明胶海绵纱条抽取时出血少,填塞后的鼻腔反应轻。结论夹层明胶海绵油纱条是一种物美价廉的鼻内窥镜手术后填塞止血的材料。     

Sonographic appearance of a retained surgical sponge in the neck

We report the sonographic appearance and clinical course of a retained surgical sponge in the neck beginning 6 months after a partial thyroidectomy. Sonograms showed a subcutaneous curvilinear hyperechoic interface with marked acoustic shadowing obscuring the left side of the neck. Three months later, a fistulous tract could be seen. Surgical exploration revealed a florid foreign tissue reaction due to a retained surgical sponge. Early diagnosis of retained sponges is important to enable expeditious removal before complications develop.     

An unusual presentation of chronic lymphocytic leukemia/small lymphocytic lymphoma on mammography: Case report

Although rare, breast CLL/SLL should be considered in the differential diagnosis of a breast mass. A high index of suspicion is needed to differentiate this neoplasm from more common breast carcinomas like solid variant of invasive lobular carcinoma.