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This article reports the case of a 45-year-old male immunocompetent patient who presented with acute epigastric pain and vomiting. Diagnostic tests confirmed a recent cytomegalovirus (CMV) infection as a contributory cause of a florid gastric ulcer. Primary CMV infections affecting the upper gastrointestinal tract are rare in immunocompetent adults. In this case treatment with a proton pump inhibitor and eradication of concomitant Helicobacter pylori colonization led to a full recovery. Anti-CMV treatment was not necessary.  相似文献   

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An age group of patients with endoscopically ascertained florid ventricular ulcer was asked with regard to the aspects own anamnesis and family anamnesis, social descent, social state, sparetime planning, alcohol consumption, nicotine consumption as well as use of analgesics. After the control of the course the patients were subdivided into such ones with healing of the ulcer within 12 weeks and such ones with retarded healing. As comparative groups served patients with duodenal ulcer and patients with functional gastropathy. As a result the family anamnesis does not bring any significant differences. Male patients with retardedly healing ventricular ulcer in 23% of the cases suffered from diabetes mellitus and/or hypertension, before the first appearance of the disease they more frequently performed a responsible activity and were more frequently on shift work team patients with a healing corresponding to time. Females with retarded healing of the ventricular ulcer have in a higher percentage family problems and significantly more frequently take analgesics than the comparative groups. A decreased adaptation of the patients with ventricular ulcer with retarded healing is discussed and they are compared with the patients with duodenal ulcer.  相似文献   

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Sarcina ventriculi is a Gram positive organism,which has been reported to be found rarely,in the gastric specimens of patients with gastroparesis.Only eight cases of Sarcina,isolated from gastric specimens have been reported so far.Sarcina has been implicated in the development of gastric ulcers,emphysematous gastritis and gastric perforation.We report a case of 73-year-old male,with history of prior Billroth Ⅱ surgery and truncal vagotomy,who presented for further evaluation of iron deficiency anemia.An upper endoscopy revealed diffuse gastric erythema,along with retained food.Biopsies revealed marked inflammation with ulcer bed formation and presence of Sarcina organisms.The patient was treated with ciprofloxacin and metronidazole for 1 wk,and a repeat endoscopy showed improvement of erythema,along with clearance of Sarcina organisms.Review of reported cases including ours suggests that Sarcina is more frequently an innocent bystander rather than a pathogenic organism.However,given its association with life threatening illness in two reported cases,it may be prudent to treat with antibiotics and anti-ulcer therapy,until further understanding is achieved.  相似文献   

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The half life time (T 1/2) of gastric emptying was measured in 53 patients suffering from atrophic gastritis or gastric ulceration, by use of a radiolabelled standardized test-meal. In healthy controls the T 1/2 was 58.8 +/- 9.1 min (median 59 min). In 35 gastric ulcer patients the T 1/2 of median 85 min was significantly slowed if compared to the normal value (2 p less than 0.01). After healing of the ulcer in 12 patients this value returned to normal. In 8 patients with diffusely atrophic gastritis the T 1/2 value was slowed significantly (median 123 min), if the gastritis was confined to the antrum, gastric emptying was accelerated (median 48 min).  相似文献   

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Kann PH 《Der Internist》2005,46(9):1047-1052
In adult patients with growth hormone deficiency due to organic hypopituitarism, substitution with growth hormone is very useful and well established. Positive influence on numerous target parameters has been investigated in randomised controlled trials (evidence level I) and could be documented. Thus, growth hormone substitution in hypopituitarism is scientifically founded and has been admitted by the authorities in the European Union. Concerning pharmacotherapy with growth hormone in healthy elderly persons without pituitary disease and also doping in sports, the situation is completely different. Use of growth hormone in these circumstances has not sufficiently been investigated concerning indications, efficacy and safety. Ethical and economical aspects have not been evaluated yet. Serious concerns about the therapeutic safety need to be considered.  相似文献   

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Zusammenfassung Die Computertomographie (CT) erm?glicht eine ?tiologische und pathophysiologische Differenzierung des Syndroms „Schlaganfall” und schafft damit die Voraussetzungen für eine gezielte Behandlung. Diese Arbeit beschreibt die Sicherheit der diagnostischen Aussage bei Patienten mit Schlaganfall und den Einfluss des nativen CT-Befundes auf die Diagnose, die Behandlung und die Prognose. Die wichtigsten und hoch sensitiven Aussagen der CT bestehen im Ausschluss einer intrakraniellen Blutung und in der Abbildung des isch?mischen Hirn?dems. Patienten ohne isch?mischen Hirn?dem trotz Schlaganfallsymptomatik haben in der Regel eine guten spontanen Verlauf. Patienten mit begrenztem ?dem in einem arteriellen Territorium profitieren von der Thrombolyse. Patienten mit ausgedehntem Hirn?dem (>ein Drittel des Territoriums der A. cerebri media oder >150ml) profitieren nicht von der Thrombolyse und tragen ein hohes Risiko für eine weitere klinische Verschlechterung. Eingegangen: 28. Januar 2001 Akzeptiert: 14. M?rz 2001  相似文献   

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Over the last decade, major progress has been made in liver resection as well as in liver transplantation for central cholangiocarcinoma. In our own experience of more than 270 patients in whom either resection or transplantation was performed during the last 19 years, a surgical concept combining an extended right hepatic resection and a principal portal vein resection has emerged as the most favorable technique. It achieves formally curative resections in 80% of the patients although a considerable share of patients suffering from Bismuth-Corlette type IV tumors is included. The 5-year survival rate in these patients is 61%. The most promising strategy in liver transplantation is based on neoadjuvant radiochemotherapy as proposed and reported by the Mayo Clinic group. The Mayo Clinic group has achieved a 5-year post-transplant survival of 83% in their patients, which is an outstanding and unprecedented figure that a few years ago would not have been considered to be a realistic goal in any type of treatment for cholangiocarcinoma.  相似文献   

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Ohne Zusammenfassung  相似文献   

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Journal of Cancer Research and Clinical Oncology - Das chromosomale Geschlecht von Portio- und von Bronchialcarcinomen des Mannes wurde bestimmt. Bei 50 untersuchten Portiocarcinomen fanden sich im...  相似文献   

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