麦粒灸正反阿是穴治疗桡骨茎突狭窄性腱鞘炎40例

目的观察麦粒灸正反阿是穴治疗桡骨茎突狭窄性腱鞘炎的疗效。方法 80例患者随机分为治疗组40例和对照组40例,治疗组麦粒灸正反阿是穴治疗;对照组普通针刺阿是穴治疗;结合视觉模拟评分(VAS)情况观察疗效。结果治疗组总有效率为95.00%,优于对照组总有效率80.00%(P0.05);治疗后两组VAS均有明显改善,与治疗前比较差异具有统计学意义(P0.05),治疗组效果较对照组显著,具有统计学意义(P0.05)。结论麦粒灸正反阿是穴治疗桡骨茎突狭窄性腱鞘炎有显著疗效。     

肉桂艾绒直接灸治疗桡骨茎突狭窄性腱鞘炎30例

<正>桡骨茎突狭窄性腱鞘炎是临床常见病,临床表现为发病时握物无力,桡骨茎突处肿胀疼痛。笔者采用肉桂艾绒直接灸,取得较好疗效,现报道如下。1临床资料1.1一般资料选择浙江省医疗健康集团杭州医院针灸科门诊2012年8月—2018年8月期间确诊为桡骨茎突狭窄性腱鞘炎患者60例,均为女性,采用随机数字表法分为治疗组和对照组,每组30例。本研究经过单位伦理委员会审核通过,患者均签署知     

阿是穴压灸联合电针治疗桡骨茎突狭窄性腱鞘炎的临床研究

【目的】观察阿是穴压灸联合电针治疗桡骨茎突狭窄性腱鞘炎的临床疗效,为临床治疗桡骨茎突狭窄性腱鞘炎提供新的思路。【方法】将80例桡骨茎突狭窄性腱鞘炎患者随机分为观察组和对照组,每组各40例,观察组给予阿是穴压灸联合电针治疗,对照组给予单纯电针治疗。每周治疗1次,连续治疗3次为1个疗程。治疗3周后,评价2组的临床疗效,观察2组患者治疗前后视觉模拟量表（VAS）评分的变化情况,以及Quinnell分级评分的变化情况。治疗3个月后随访,评价2组的远期疗效。【结果】（1）研究过程中,观察组失访3例,对照组失访4例。最终观察组37例、对照组36例纳入疗效统计。（2）治疗后,2组患者的VAS评分明显改善（P<0.05）,且观察组在改善VAS评分方面明显优于对照组,差异有统计学意义（P<0.05）。（3）治疗后,2组患者的Quinnell评分明显改善（P<0.05）,且观察组在改善Quinnell评分方面明显优于对照组,差异有统计学意义（P<0.05）。（4）观察组总有效率为94.59%(35/37),对照组为83.33%(30/36)。观察组总有效率稍高于对照组,但差异无统计...     

温针灸联合局部封闭治疗桡骨茎突狭窄性腱鞘炎的临床研究

目的观察温针灸联合局部封闭治疗桡骨茎突狭窄性腱鞘炎的临床疗效。方法选取68例桡骨茎突狭窄性腱鞘炎患者随机分成观察组和对照组(每组各34例),对照组给予单纯局部封闭治疗,观察组在对照组基础上给予温针灸治疗,观察两组患者治疗前后视觉模拟评分法(visual analog scale,VAS)、主要症状及体征评分,比较治疗后两组患者临床疗效。结果治疗后,两组患者VAS评分和主症及体征评分总分均较本组治疗前有所降低,差异有统计学意义(P0.05或P0.01),且观察组评分均低于对照组,差异有统计学意义(P0.05);观察组总有效率高于对照组,两组比较差异有统计学意义(P0.05)。结论温针灸联合局部封闭治疗桡骨茎突狭窄性腱鞘炎效果显著,且优于单纯局部封闭治疗,值得临床进一步研究推广。     

综合手法治疗桡骨茎突狭窄性腱鞘炎的临床观察

[目的]探讨综合手法治疗桡骨茎突狭窄性腱鞘炎的临床疗效。[方法]将符合诊断标准的56例桡骨茎突狭窄性腱鞘炎患者,分为治疗组和对照组各28例。治疗组运用综合手法治疗,对照组运用常规手法治疗。两组分别隔天治疗1次,治疗5次为1个疗程,均治疗3个疗程。[结果]治疗组有效率为89．3％,对照组有效率为75．0％,两组比较有显著性差异（P〈0．05）。[结论]综合手法治疗桡骨茎突狭窄性腱鞘炎,疗效满意,有临床推广价值。     

再灌注手法治疗桡骨茎突狭窄性腱鞘炎的疗效观察

目的:探究再灌注手法治疗桡骨茎突狭窄性腱鞘炎的临床疗效。方法:选取2020年12月至2021年12月某中医院收治的桡骨茎突狭窄性腱鞘炎患者80例，应用随机数字表法分为对照组和试验组，每组各40例。对照组患者予以双氯芬酸二乙胺乳胶剂涂抹治疗配合腕关节制动，试验组患者在对照组治疗的基础上配合再灌注手法。记录两组患者治疗1周后、治疗后3周的VAS疼痛评分、腕关节尺偏角度、拇指外展角度，全面评价其临床疗效。结果:对比治疗前，治疗1周后、治疗后3周时两组患者的VAS疼痛评分值、腕关节尺偏角度、拇指活动度均有所改善(P<0.05),且试验组患者改善程度优于同时期对照组(P<0.05)。治疗1周后，两组患者临床治疗总有效率差异无统计学意义(P>0.05);试验组治愈率(32.5%)高于对照组治愈率(7.5%)(P<0.05)。治疗后3周回访，试验组患者临床治疗总有效率高于对照组(P<0.01)。结论:再灌注手法在治疗桡骨茎突狭窄性腱鞘炎患者的临床症状方面疗效突出，同时在改善疼痛症状、腕关节活动度的远期疗效方面较对照组更为稳定。     

浮针治疗桡骨茎突狭窄性腱鞘炎的疗效观察

[目的]观察浮针治疗桡骨茎突狭窄性腱鞘炎的临床治疗效果。[方法]将73例桡骨茎突狭窄性腱鞘炎患者按随机数字表法分为治疗组38例和对照组35例。治疗组患者采用浮针疗法进行治疗,对照组患者采用常规电针进行治疗。记录并比较两组患者的临床疗效、视觉模拟评分法(Visual Analogue Scale,VAS)、Cooney腕关节评分法及腕关节尺偏活动度等评分。[结果]两组的VAS评分均较治疗前明显降低,Cooney腕关节评分、腕关节尺偏活动度均较治疗前显著升高,差异具有统计学意义(P0.05);治疗后,治疗组VAS评分明显低于对照组,Cooney腕关节评分、腕关节尺偏活动度均显著高于对照组,差异具有统计学意义(P0.05);治疗组临床治疗效果明显优于对照组,差异具有统计学意义(P0.05)。[结论]浮针疗法治疗桡骨茎突狭窄性腱鞘炎疗效优于常规电针治疗,且操作安全、简便、无痛苦,值得在临床上广泛应用。     

小针刀治疗桡骨茎突狭窄性腱鞘炎30例的疗效观察

目的:观察小针刀在治疗桡骨茎突狭窄性腱鞘炎中的疗效。方法:通过随机分针刀组(治疗组)和封闭组(对照组)共60例,各30例,对桡骨茎突狭窄性腱鞘炎进行治,疗观察其治疗后一天,三个月的疗效。结果:针刀组有效率96.6%,封闭组有效率90%,针刀组疗效优于封闭组。术后一天VAS评分下降封闭组交针刀组低,但术后三个月针刀组下降比封闭组低,有统计学意义(P<0.05)。结论:小针刀治疗短期疗效不如封闭治疗。但是长期疗效优于封闭,且小针刀廉,简,便是治疗桡骨茎突狭窄性腱鞘炎的首选方法。     

体外冲击波治疗桡骨茎突狭窄性腱鞘炎临床疗效观察

目的:对体外冲击波治疗桡骨茎突狭窄性腱鞘炎的临床疗效进行观察研究。方法:随机抽取2012年12月~2013年12月本院接诊的59例桡骨茎突狭窄性腱鞘炎患者作为研究对象,将其随机分为两组,观察组30例,对照组29例,对观察组患者行体外冲击波疗法,对照组患者采取敷双氯芬酸二乙胺疗法,比较两组患者的疼痛度和有效率。结果:治疗后,两组患者的疼痛情况均有所改善,与治疗前比较差异显著(P0.05),观察组患者评分显著优于对照组,二者差异显著(P0.05);观察组患者总有效率100.0%,治愈率93.3%均显著优于对照组二者差异显著(P0.05)。结论:体外冲击波治疗桡骨茎突狭窄性腱鞘炎临床疗效显著,可有效缓解患者疼痛,值得临床应用。     

针灸结合局部封闭治疗桡骨茎突狭窄性腱鞘炎疗效观察

目的 探讨针灸结合局部封闭治疗桡骨茎突狭窄性腱鞘炎的应用效果. 方法将94例病人随机分为两组,对照组采用局部封闭治疗,治疗组采用针灸结合局部封闭治疗. 结果治疗组总有效率为98.04%,对照组总有效率为93.48%,两组总有效率比较差异有显著性(P＜0.05).结论 针灸结合局部封闭比单独采用局部封闭治疗桡骨茎突狭窄性腱鞘炎疗效更佳.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.