锥形束CT介导下超声骨刀联合微创技术拔除下颌阻生第三磨牙的效果研究

目的:观察在锥形束CT(CBCT)介导下超声骨刀联合微创技术拔除下颌阻生第三磨牙(IMTM)的效果。方法:选择拔除IMTM的106例患者,遵照随机原则分为对照组、试验组,每组各53例,分别在常规X线、CBCT介导下超声骨刀联合微创开展拔除术,记录并比较拔除术中并发症及术后症状。结果:试验组并发症发生率为6.35%,低于对照组的22.95%,差异有统计学意义(P<0.05);术后试验组患者疼痛评分颌面部肿胀程度均轻于对照组,差异均有统计学意义(P<0.05);术后试验组、对照组断根率依次为3.77%、22.64%,差异有统计学意义(P<0.05)。结论:CBCT介导下超声骨刀联合微创拔除IMTM,能降低IMTM拔除术中及术后并发症,利于患者拔牙创愈合,降低拔牙术中及术后不适感,值得推广。     

锥形束CT介导下超声骨刀联合微创拔牙术治疗下颌阻生第三磨牙患者的效果

目的 探讨锥形束CT(CBCT)介导下超声骨刀联合微创拔牙术治疗下颌阻生第三磨牙(IMTM)患者的效果.方法 选取2019年1月至2021年3月洛宁县人民医院收治的138例IMTM患者进行前瞻性随机平行对照研究,按随机数字表法分成CBCT组(69例)、X线组(69例).X线组接受X线超声骨刀联合微创拔牙术治疗,CBCT...     

应用微创拔牙术拔除下颌阻生第三磨牙的临床试验

目的评价微创拔牙技术在临床拔除下颌阻生第三磨牙的应用效果。方法选择临床需要拔除下颌阻生第三磨牙的患者100例,随机分为微创拔牙组(50例)和传统拔牙组(50例),分别应用微创拔牙技术和传统拔牙技术拔除下颌阻生第三磨牙,并对两组的术中疼痛、手术时间及术后并发症进行比较。结果微创拔牙组在拔除下颌阻生第三磨牙手术中的重度疼痛发生率(6%)和术后中或重度并发症发生率(18%)均低于传统拔牙组的36%和56%,微创拔牙组的手术时间平均为(20±5)min短于传统拔牙组的平均时间为(35±9)min,差异均有统计学意义(P<0.05)。结论应用微创拔牙法拔除下颌阻生第三磨牙,能明显减少患者术中、术后并发症的发生率,有效缩短拔牙时间,值得在临床加以推广应用。     

锥体束CT介导下超声骨刀联合高速涡轮法在下颌阻生第三磨牙微创拔除中的应用

目的：探讨锥体束CT介导下超声骨刀联合高速涡轮钻法在下颌阻生第三磨牙微创拔除中的应用效果。方法：选取2018年3月—2021年3月在兰州大学口腔医院择期行下颌阻生第三磨牙拔除术的122例患者为研究对象，随机分为对照组和研究组，每组61例，对照组应用锥体束CT介导下高速涡轮钻法，研究组应用锥体束CT介导下超声骨刀联合高速涡轮钻法。比较两组手术时间、术中出血量和术后疼痛评分；比较两组术后面部肿胀和张口受限程度；比较两组邻牙损伤、神经损伤、术后出血和干槽症等术中术后并发症总发生率。结果：研究组手术时间、术中出血量及术后24h疼痛VAS评分均低于对照组(均P<0.05);术后面部肿胀程度和张口受限程度均比对照组轻微，术中术后并发症总发生率均低于对照组(均P<0.05)。结论：锥体束CT介导下超声骨刀联合高速涡轮钻法拔除下颌阻生第三磨牙有利于术前准确评估和术中精准操作，能够缩短手术时间，并避免或降低术中、术后并发症的发生。     

微创拔牙术在下颌阻生智齿拔除中的应用效果

目的：研究微创拔牙术在拔出下颌阻生智齿的效果。方法随机抽查口腔科2015年上半年诊治的32例下颌阻生智齿患者,随机分成2组,应用传统拔牙术拔出对照组患者的智齿,运用微创拔牙术拔出研究组患者的智齿,比较2组的治疗效果。结果研究组的手术时间为(19.73±5.41)min,术后持续疼痛时间为(11.72±2.11)h,短于对照组的(36.17±5.34)min、(23.47±5.21)h;研究组并发症发生率为6.25%,对照组并发症发生率为37.5%,差异均具有统计学意义（P＜0.05）。结论微创拔牙术在下颌阻生智齿拔出中的应用效果良好,并发症发生时率较低,可广泛应用。     

微创拔除下颌复杂阻生第三磨牙180例临床观察

目的探讨微创拔牙术在下颌复杂阻生第三磨牙拔除中的应用效果。方法我科2007～2009年拔除的下颌复杂阻生第三磨牙患者180例,用高速仰角涡轮手机适量去骨、切割牙齿分块拔除。结果 180颗阻生第三磨牙均在20min内拔除,其中左侧第三磨牙96例(53.3%),右侧第三磨牙84例(46.7%)。阻生第三磨牙的类型:水平92例(51.1%),近中57(31.7%),垂直23(12.7%),远中5(2.8%),颊向3(1.7%)。术后未出现感染,无干槽症和下颌神经损伤病例。结论微创拔牙术缩短了手术时间,减少了术后并发症的发生,是拔除下颌复杂阻生第三磨牙的良好方法,值得临床推广。     

超声骨刀在下颌第三磨牙拔除术中的临床应用

目的研究超声骨刀在拔除下颌阻生第三磨牙中的临床效果和应用价值。方法选取220例下颌阻生第三磨牙患者,随机分为甲组和乙组,每组各110例。甲组采用超声骨刀拔除法,乙组采用锤凿拔除法。对比两组术后并发症发生情况。结果超声骨刀组术后中重度并发症发生率低于锤凿拔除法。结论超声骨刀有效降低了手术并发症,安全、高效,值得推广应用。     

微创拔牙术在下颌阻生智齿拔除中的应用

目的：分析微创拔牙术在下颌阻生智齿拔除中的应用效果。方法：资料随机选取我院口腔科2013年1月～2014年1月收治的64例下颌阻生智齿患者,将其分为两组,给予对照组患者传统凿骨劈冠拔牙术,研究组则采用微创拔牙术,并对比分析两组治疗的效果。结果：研究组手术时间、术后疼痛度及并发症发生率等,均优于对照组,比较差异有统计学方面的意义（P＜0．05）。结论：采用微创拔牙术拔除患者下颌阻生智齿的效果较为良好,并发症较少,值得推广应用。     

分析微创拔牙法与传统拔牙法在下颌阻生齿拔除中的效果

目的下颌阻生拔除中应用微创拔牙法在和传统拔牙法的临床效果比较。方法选取66例我院2015年10月至2016年10月收治的下颌阻生齿拔除患者,分为研究组与对照组,研究组应用微创拔牙法,对照组应用传统拔牙法拔除,观察比较两组患者的拔除效果。结果研究组拔牙时间为(15.4±2.6)min,对照组为(37.5±4.8)min,差异明显(P0.05)。研究组拔牙的VAS评分显著低于对照组(P0.05)。研究组1例发生并发症,发生率为3.03%,对照组发生并发症8例,并发症发生率为24.24%,差异有统计学意义(P0.05)。结论下颌阻生齿拔除应用微创拔牙法,能够有效缩短拔牙时间,减轻患者疼痛,且并发症少,值得推广。     

超声骨刀拔除下颌阻生智齿的效果观察及护理

目的：观察超声骨刀拔除下颌阻生智齿的临床效果,总结临床护理方法。方法：选取我院收治的120例下颌阻生智齿患者作为研究对象,使用随机数字表法将其分为2组,每组60例,对照组采用锤凿劈冠法,观察组应用超声骨刀。比较两组患者的拔牙效果。结果：观察组患者的平均拔牙时间为（16．0±4．9）min,对照组为（31．2±8．5）min,观察组的拔牙时间明显比对照组更短,P＜0．05,差异具有统计学意义;观察组患者并发症发生率显著低于对照组,P＜0．05,差异具有统计学意义。结论：与传统的劈冠法相比,应用超声骨刀拔除下颌阻生智齿所需时间更短,术后并发症更少,配合良好的护理操作,有助于顺利完成拔牙。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.