海绵窦上壁的应用解剖学研究

目的为经海绵窦(CS)上壁的手术提供解剖学资料。方法解剖观测15例(30侧)成人头颅标本CS上壁的解剖三角、脑膜及相关结构。结果①CS上壁为不规则的四边形,可分出3个解剖三角:颈动脉三角、动眼神经三角及前内侧三角;②动眼神经门的长径为(5.67±0.87)mm,短径为(1.09±0.35)mm;动眼神经鞘膜袋前深(4.69±1.31)mm,后深(6.50±1.58)mm;③上壁的脑膜结构有镰状韧带、前岩床皱襞、后岩床皱襞、床突间韧带,颈动脉床突韧带、颈动脉穴及颈动脉领、动眼神经鞘膜袋、远环及近环等,膜结构在前床突(ACP)尖形成复杂的膜复合体。结论CS上壁的解剖三角可作为CS的手术入路,其脑膜结构对于手术也具有重要意义。     

动眼神经冠状断层解剖与MRI

目的：探讨冠状断面上动眼神经的解剖特征与MRI表现,为相关病变的影像诊断和外科手术提供解剖学依据。方法：取用成人尸头标本15例,经冰冻后,用电动断层带锯制成连续断层标本;用3．0TMR扫描仪,获取10例成人志愿者的3D—CISS序列图像;在上述断层标本与MRI图像上观察动眼神经在冠状断面上的走行规律及毗邻关系。结果：动眼神经在经中脑脚问窝的断面上,呈“八”字形,紧贴两侧大脑脚向外下方走行,居大脑后动脉和小脑上动脉之间;在经海绵窦后份的断面上,位于“工”字形结构下端的左右两侧;在经海绵窦前份的断面上,位于前床突下方,颈内动脉的外侧;在经眶尖部的断面上,位于视神经和下直肌的外下方。结论：在冠状断面上可清晰显示动眼神经脑池段、海绵窦段和眶尖段的位置及其毗邻关系。     

标准翼点入路前床突切除前后颈内动脉动眼神经三角的不同显露

目的：量化和比较从硬膜外切除前床突前后颈内动脉动眼神经三角（COT）显露面积。方法：15具尸体头颅标本进行双侧解剖。硬膜外切除前床突前后,测量点如下：①颈内动脉分叉点至前床突尖（A）及至远环（A’）;②颈内动脉分叉点至动眼神经被天幕返折挡住点（B）及天幕返折切开后至动眼神经孔（B’）;③前床突尖至动眼神经被天幕返折挡住点（c）和从远环至动眼神经孔（C’）。在前床突切除前后分别计算COT面积（分别为三角形ABC面积和三角形A’B’C’面积）。结果：所测平均值如下。A,（9．03±0．928）mm;A’,（13．50±0．861）mm;B,（7．63±1．245）mm,B’,（9．87±1．196）mm;C,（6．97±0．964）mm;C’,（9．27±1．285）inm;三角形ABC面积为（25．02±5．881）mm2,A’B’C’面积为（44．78±9．174）mm2。左右两侧长度和COT面积测量值比较差异无统计学意义（P〉0．05）。结论：经硬膜外切除前床突后在COT显露面积比切除前增加了近两倍。在切除鞍旁区病变和基底动脉顶端病变时,增加的显露对手术操作会有重要帮助。     

经颅海绵窦手术的显微外科解剖及临床应用

目的：研究额颞眶-颧弓入路中,海绵窦的不同切开方法对其显微结构的显露,为海绵窦病变的直接手术提供安全手术入路。方法：10例成人头颅标本,采用经额颞眶-颧弓开颅,在显微镜下对海绵窦的侧方硬膜外,侧方硬膜下,及上方入路进行解剖学观察。并对16例海绵窦病变手术治疗的临床资料进行分析。结果：外侧硬膜外入路可用于显露三叉神经第2、3支,三叉神经节,海绵窦内颈内动脉后垂直段,外展神经及岩骨颈内动脉水平段;侧方硬膜下入路可用于显露海绵窦外侧前下,后上静脉间隙,以及所有走行在海绵窦内的颅神经和海绵窦内颈内动脉水平段;上方入路可用于显露海绵窦内侧、外侧及后上间隙,海绵窦内ICA水平段、前膝、前垂直段及床突段的内侧面,以及垂体的外侧面。结论：依据海绵窦内病变的位置不同,在额颞眶--颧弓入路中采用不同的手术方法切开海绵窦,既可安全地显露病变,又可保护重要的神经和血管。     

经鼻入路蝶窦外侧壁和海绵窦内侧壁的显微解剖

目的　研究经鼻入路视角下蝶窦外侧壁和海绵窦内侧壁的显微解剖特征,为相关手术提供形态学依据。 方法　10例防腐尸颅按经鼻路径在显微镜下进行解剖,观测视神经、颈内动脉和蝶窦外侧壁的关系,测量前鼻棘与视神经管眶口、颈内动脉隆凸最凸点之间的距离,以及与鼻底平面的角度。 结果　颈内动脉和视神经在蝶窦外侧壁上形成隆凸,两者之间呈“＞”字形,前鼻棘与颈内动脉隆起最凸点之间的距离为（62.18±5.12）mm,与鼻底平面的夹角为（36.8±3.4）°,与视神经管眶口的距离为（69.24±3.95）mm,与鼻底平面的夹角（41.4±3.0）°。颈内动脉海绵窦段可分为鞍旁部和斜坡旁部,鞍旁部与垂体外侧壁关系最为密切,鞍旁部至中线的距离为（9.06±1.34）mm。海绵窦内侧壁由鞍旁部和蝶窦旁部组成。 结论　熟悉蝶窦外侧壁和海绵窦内侧壁的解剖学特点,对于术中定位,安全处理海绵窦病变有重要意义。     

蝶鞍区塑化薄片断层解剖学研究

为了给临床蝶鞍区手术提供详细的解剖学资料，用中年男性标本３０例，采用Ｐｌａｓｔｉｎａｔｉｏｎ技术，分别作成蝶区连续横、矢、冠状薄片断层标本，进行解剖学观测，结果显示：董体的左右径大于前后径或上下径，对于垂体病变，宜进行三方位对照观察，以了解垂体的形态变化。展神经与海绵窦外侧壁之间有间隙存在，说明展神经并不走行于外侧壁中，而是位海绵窦内。紧贴视交叉的外侧，颈内动脉由海绵窦段的前升冲突芊     

内窥镜下经鼻蝶入路视神经管减压的解剖学研究

目的：为内窥镜卜经鼻蝶入路进行视神经管减压的手术方法建立解剖学基础。方法：选用8例成人头颅标本在内窥镜下进行解剖观察。模拟内窥镜下经鼻蝶于术入路，分别采用经鼻中隔旁入路、经中鼻道入路、经中鼻四切除三种手术入路对蝶窦外侧壁和后壁进行解剖观察。打开蝶窦前壁后进入蝶窦，咬除蝶窦间隔，去除蝶安粘膜，暴露蝶窦后壁和后外侧壁，对视神经管及周围结构进行逐层解剖。结果：在蝶窦后壁和外侧壁的所有解剖标志中，视神经-颈内动脉隐窝是相对恒定的解剖标志，在视神经管区各层中该隐窝是恒定的唯一骨性解剖标志。视神经-颈内动脉隐窝毗邻视神经、海绵窦、海绵窦内颈内动脉、眼动脉、动眼神经，是视神经管内段和颅内段的分界。两侧视冲经-颈内动脉隐窝的连线是鞍结节的投影。结论：视伸经-颈内动脉隐窝在视神经管减压术中是非常重要的解剖标志。     

Microsurgical Anatomy of the Oculomotor Nerve

The oculomotor nerve supplies the extraocular muscles. It also supplies the ciliary and sphincter pupillae muscles through the ciliary ganglion. The nerve fibers leave the midbrain through the most medial part of the cerebral peduncle and enter the interpeduncular cistern. After the oculomotor nerve emerges from the interpeduncular fossa, it enters the cavernous sinus slightly lateral and anterior to the dorsum sellae. It enters the orbit through the superior orbital fissure, after exiting the cavernous sinus, to innervate the extraocular muscles. Therefore, knowledge of the detailed anatomy and pathway of the oculomotor nerve is critical for the management of lesions located in the middle cranial fossa and the clival, cavernous, and orbital regions. This review describes the microsurgical anatomy of the oculomotor nerve and presents pictures illustrating this nerve and its surrounding connective and neurovascular structures. Clin. Anat. 30:21–31, 2017. © 2016 Wiley Periodicals, Inc.     

脑神经海绵窦段的显微解剖及其临床应用

目的　为海绵窦 (cavernoussinus,CS)直接手术提供解剖学基础。方法　在手术显微镜下对 15例 (30侧 )成人头颅标本CS内脑神经位置、行径以及与颈内动脉CS段的毗邻关系进行观测。结果　①动眼神经入窦点在前床突尖后方 (4 5 7± 1 0 5 )mm ,与滑车神经、眼神经垂直距离分别为 (2 2 0± 0 6 7)mm和 (4 37± 1 35 )mm。②滑车神经入窦点与眼神经垂直距离为 (5 5 2± 1 0 6 )mm。滑车神经CS段行程形状可分为三型。③颈内动脉后曲顶高出眼神经和展神经上缘分别为 (5 5 2± 1 84)mm和 (6 6 0± 1 94)mm。④经前床窦尖外侧或外下方时 ,动眼神经、滑车神经及眼神经与前床突尖垂直距离分别为 (1 85±0 75 )mm、(5 30± 1 0 4)mm和 (6 6 1± 1 6 3)mm。结论　掌握脑神经CS段的显微解剖对CS的直接手术具有重要意义。     

眶上裂区临床应用解剖研究进展

眶上裂区是眼眶与颅中窝沟通的重要通道,动眼神经、滑车神经、展神经、三叉神经第一支（ 眼神经）、 眼上静脉、眼下静脉等诸多重要神经、血管从中穿行,并且与视神经、颈内动脉、海绵窦等结构关系密切。眶上 裂区解剖对于颅底手术至关重要,手术时如损伤眶上裂区的神经、血管结构将导致严重的并发症。现就眶上裂区 的大体、显微及内镜临床应用解剖作简要综述。     

More actors, different play: sphenoethmoid cell intimately related to the maxillary nerve canal and cavernous sinus apex

The sphenoid sinus is one of the most morphologically variable and surgically important structures of the skull base. Located below the sella turcica, neighbored by parasellar regions, such as the orbital apex, pterygopalatine fossa and lateral sellar region (cavernous sinus), it is clinically related to these and surgically relevant as corridor for various approaches. Moreover, at the sphenoethmoidal junction, important variations occur, most of these related to the presence of the Onodi cells and the intrasinusal protrusions of the optic nerve. That is why any identified and previously undescribed morphological variation at that level must be added to the well-established protocols, clinical and surgical. During a retrospective CT study of the sphenoid sinus anatomical features a previously unreported morphology was encountered and is reported here. It refers to a unilateral sphenoethmoid cell (SEC), Onodi-positive, not only overriding the superior aspect of the sphenoid but also its lateral side to get intimately related to the maxillary nerve. As that SEC expanded medially to the cavernous sinus apex, it altered the usual endosinusal morphological correlations and also added itself within the limits of the Mullan's triangle. It appears so that such postero-infero-lateral extended pneumatization of an Onodi cell alters the surgical landmarks and also can blur clinical pictures, by adding maxillary and pterygopalatine signs and symptoms.     

Microsurgical anatomy of the abducens nerve

The aim of this study is to demonstrate and review the detailed microsurgical anatomy of the abducens nerve and surrounding structures along its entire course and to provide its topographic measurements. Ten cadaveric heads were examined using ×3 to ×40 magnification after the arteries and veins were injected with colored silicone. Both sides of each cadaveric head were dissected using different skull base approaches to demonstrate the entire course of the abducens nerve from the pontomedullary sulcus to the lateral rectus muscle. The anatomy of the petroclival area and the cavernous sinus through which the abducens nerve passes are complex due to the high density of critically important neural and vascular structures. The abducens nerve has angulations and fixation points along its course that put the nerve at risk in many clinical situations. From a surgical viewpoint, the petrous tubercle of the petrous apex is an intraoperative landmark to avoid damage to the abducens nerve. The abducens nerve is quite different from the other nerves. No other cranial nerve has a long intradural path with angulations and fixations such as the abducens nerve in petroclival venous confluence. A precise knowledge of the relationship between the abducens nerve and surrounding structures has allowed neurosurgeon to approach the clivus, petroclival area, cavernous sinus, and superior orbital fissure without surgical complications. Clin. Anat. 25:1030–1042, 2012. © 2012 Wiley Periodicals, Inc.     

颞下锁孔硬膜下Kawase入路的内镜解剖学研究

目的 探讨神经内镜模拟颞下锁孔硬膜下Kawase入路手术可行性和适应证。方法 成人尸头湿标本8具（16侧）,模拟神经内镜颞下锁孔硬膜下Kawase入路,观察内镜下显露的最大视野,辨识弓状隆起、三叉神经、岩浅大神经、岩上窦等解剖结构,标识Kawase三角的边界,测量不同磨除范围下Kawase三角的各边长,显露小脑膜切迹间隙、脑干腹外侧、上中岩斜区、中下岩斜区交界处及其邻近结构。结果 弓状隆起最高点到棘孔、岩浅大神经裂孔、岩浅大神经与下颌神经的交点;三叉神经压迹外侧缘的最短距离分别为（22.90±2.34）mm、（14.05±2.09）mm、（24.94±1.98）mm、（23.49±2.38）mm;Kawase三角磨除面积为（3.04±0.47）cm2,扩大磨除Kawase三角面积为（3.7±0.69）cm2,平均增加了0.66 cm2的面积。结论 经神经内镜颞下锁孔硬膜下Kawase入路避免了对脑膜中动脉的损伤,保留了岩浅大神经。适合处理位于小脑幕切迹间隙,上、中岩斜区,中、下岩斜区交界处,部分桥小脑角脑干腹外侧广泛区域的肿瘤、动脉瘤等病变。     

Meckel腔及毗邻结构显微解剖在中颅底入路中的应用研究

目的　研究Meckel腔及毗邻结构的显微外科解剖关系,为临床手术治疗相关疾病提供解剖学依据。 方法　成人尸头标本10例（20侧）,采用手术显微镜观察Meckel腔及毗邻结构。 结果 　Meckel腔是颅后窝向颅中窝后内侧突入的硬脑膜凹陷,内有三叉神经运动根和感觉根、三叉神经节及三叉神经池,腔前后长（14.53±0.98）mm,内外宽(15.24±1.29)mm,上下厚(4.95±0.54)mm。三叉神经孔至Dorello管开口(9.25±1.14)mm,至内耳道开口(15.30±1.14)mm。Meckel腔内侧壁为各壁中比较薄的,内侧壁后部与颞骨岩尖部岩蝶韧带相贴,毗邻Dorell管;下壁前方隔岩舌韧带与颈内动脉破裂孔段相邻。 结论　Meckel腔内侧壁的硬膜脑膜层较为菲薄,并直接与海绵窦静脉腔隙相邻,可能是肿瘤侵入海绵窦的薄弱点之一。岩蝶韧带和岩舌韧带可以作为前部经岩手术识别展神经和颈内动脉破裂孔段的解剖结构。     

内镜经鼻入路视神经管和眼眶的解剖学

目的通过研究对视神经管和眼眶的解剖研究,为内镜经鼻入路视神经管减压和治疗眼眶内病变提供解剖基础。方法国人尸头5例,采用大体解剖和内镜下经鼻入路两种方法,观察重要的解剖标志;使用内直肌内移技术,观察视神经管和眼眶内结构的暴露情况以及重要结构的位置、毗邻、走行等。结果钩突位于中鼻甲的前下方;筛泡在钩突的后方,切开筛泡可进入筛窦;筛前后动脉是筛窦内的重要解剖标志;视神经管隆突、颈内动脉隆突和视神经管颈内动脉隆突(OCR)是蝶窦内重要的解剖标志;纸样板位于筛窦的外侧壁,切开纸样板可暴露眶内容物;在眶内,可从内直肌与下直肌之间的通路暴露视神经。在本次10侧标本中,9侧眼动脉起自于颈内动脉的床突上段;1侧眼动脉起自于颈内动脉海绵窦段。7侧眼动脉在视神经管内走行于视神经的下外侧;2侧走行于视神经的正下方;1侧走行于视神经的下内侧。结论内镜下经鼻入路可以进行视神经管和眼眶内侧部分的暴露。钩突、筛泡、筛前后动脉及后组筛窦是本入路重要解剖标志。视神经管隆突、颈内动脉隆突及视神经管颈内动脉隆突(OCR)是进行视神经管减压的重要标志。眼动脉及其眼眶内分支、筛前后动脉和颈内动脉是重要的血管结构。眼内直肌内移技术可以有助于暴露眶内解剖结构。     

眶尖区的断层解剖学研究及临床意义

目的　为眶尖区影像诊断提供断层解剖学资料。方法　应用 5 0侧成人头颅湿标本制成 0 5mm的火棉胶连续切片 ,用计算机图像分析系统对 3 6侧冠状位标本上的眶尖结构进行测量。结果　视神经管眶口处面积最小 ,管内段视神经从颅端到眶端逐渐变细 ,眼动脉进入神经经管从视神经内下方向外下方走行 ,眶上裂被Zinn腱环分为外侧区、中央区、下区 3部分。结论　冠状位是观测眶尖结构的理想层面 ,对眶尖部病变的诊断具有重要意义。     

Anatomy of the petrosphenoidal and petrolingual ligaments at the petrous apex

The petrous apex is a complex area surrounded by the cavernous sinus, Dorello's canal and Meckel's cave. The petrosphenoidal ligament (PSL) and the petrolingual ligament (PLL) are important structures located in the region. These two ligaments were examined under a surgical microscope in 10 specimens of five adult cadaveric heads fixed in formalin. They were found to span from the petrous apex to the posterior clinoid process, and the lingula of the sphenoid bone, respectively. The dural sleeve of the abducens nerve, the dorsal meningeal artery or its medial branch, and the venous blood space were located below the PSL in all specimens, and the petrous or sphenoidal insertion of the PSL varied in five specimens. The PLL invariably surrounded part of the dorsal and lateral walls of the lacerum segment of the internal carotid artery (ICA), just under the anteroinferior portion of the anteromedial wall of Meckel's cave in all specimens. The PSL and PLL are valuable anatomical landmarks for identifying the ICA and the nerves in this region. A thorough understanding of the relationship of the two ligaments with neurovascular structures is a prerequisite for surgery in and around the petrous apex. Clin. Anat. 22:302–306, 2009. © 2009 Wiley‐Liss, Inc.     

Microsurgical anatomy of the superior orbital fissure

The microanatomy of the superior orbital fissure (SOF) was studied in 96 sides of cadaver specimens. The SOF is a narrow bony cleft that lies at the apex of the orbit between the greater and lesser wings of the sphenoid. Through this fissure, many important structures enter the orbit from the middle cranial fossa including the third, fourth, sixth cranial nerves, and the ophthalmic branch of the fifth nerve. In addition, the superior opthalmamic vein exits the orbit to drain into the cavernous sinus via the SOF. The fissure can be divided into three anatomical regions by the annulus of Zinn (common annular tendon): the lateral, central, and inferior regions. The lateral wall of the SOF can also be divided between the upper and lower segments, and the angle between them was measured to be 144.27 degrees +/- 20.03 degrees . Defining these regions is useful in describing the course and placement of the nerves and vasculature in the SOF. Managing lesions at the orbital apex requires an extensive knowledge of the cranial base and the intracranial and extracranial relationships of the anatomical structures coursing through the SOF. The goal of this study was to describe the microanatomy of the SOF region in detail and to provide a reference for surgical procedures involving the orbital apex.     

蝶筛窦外侧壁应用解剖

观察５７具成人尸头标本蝶、筛窦外侧壁，以及同视神经管和颈内动脉的毗邻关系。眶板前下宽，后上窄，平均厚度为０．２ｍｍ。９３．８６％的视神经管内壁与蝶、筛窦外侧壁毗邻，且视神经管内蝶、筛窦内突出形成隆起的找率和程度同蝶、筛窦气代程度呈正相关。