Angiolipoma Larynx: A Case Report

We report an extremely rare case of angiolipoma larynx Case report and a review of the world literature concerning angiolipoma are presented. A case of tumour of the larynx in a 72-year-old male who underwent excision by a lateral pharyngotomy approach. Histopathological diagnosis was angiolipoma. 19 cases of angiolipoma have been reported from head and neck region, none from the larynx. To our knowledge this is the first report in the world literature of angiolipoma larynx.     

Clear-cell carcinoma of the larynx: review of the literature apropos of a case]

Clear cell carcinoma of the larynx is exceptional. Only six cases are described in the literature. We report a new case occurring in a 58-year-old man. The treatment consisted of a total laryngectomy with lymph node dissection followed by adjuvant irradiation. Local and regional recurrence occurred after 5 months. The patient died from the tumor's evolution 12 months after the diagnosis. The prognosis of clear cell carcinoma of the larynx is similar to the clear cell carcinoma of the lung and is unfavorable.     

Primary rhabdomyosarcoma of the larynx

Sarcomas constitute fewer than 1% of the head and neck cancers. They represent less than 1% of laryngeal cancers. Primary rhabdomyosarcoma of the larynx is an extremely rare malignancy. The available literature on this medical oddity is in the form of isolated case reports only. The purpose of this article is to add another case of primary rhabdomyosarcoma of a rare site, the larynx, of which only 36 cases have so far been reported in the world literature. The present patient, an eighteen-year-old boy is only the third case being reported from India among all reported cases of rhabdomyosarcoma of the larynx in the world literature.     

Primary oat cell carcinoma of the larynx: a case report and review of the literature.

A case of an extrapulmonary oat cell carcinoma arising in the larynx of a 45-year-old male is described. Ultrastructural study demonstrated numerous neurosecretory granules in the tumor cells identical to those described in oat cell carcinomas of the lung. Primary oat cell carcinomas of the larynx are highly malignant neoplasms. Of six previously reported acceptable cases of this rare entity, with adequate followup, all but one has died of tumor within 14 months of diagnosis. The present patient is alive without evidence of tumor 15 months following diagnosis. Aggressive therapy consisting of a combination of surgery, radiation therapy and systemic chemotherapy was utilized in this case. The use of such aggressive combination therapy appears indicated in cases of primary oat cell carcinoma of the larynx if improved survival is to be achieved.     

Clear cell carcinoma of the larynx: immunocytochemical study

A case of clear cell carcinoma of the larynx with multiple metastases is reported. The histological and immunohistochemical characteristics of this tumor are discussed as well as the main differential diagnoses. An origin from sero-mucous glands of the larynx is proposed. A literature review showed that clear cell carcinoma of the larynx is rare and is characterized by extremely high aggressiveness.     

Liposarcoma of the larynx treated with radiotherapy

Liposarcoma of the larynx is an extremely rare malignancy. Only 18 cases have been reported in the literature. We herein report the first case of primary liposarcoma of supra-glottic larynx in a 53-years old male patient successfully treated with radiotherapy in August-September 1992. He currently remains free of the disease 4.5 years since the initial diagnosis.     

Chondrosarcoma of the larynx. Case report and review of the literature

Chondrosarcoma of the larynx is a rare tumor; worldwide only about 250-300 cases have been described in the literature. We present a clinical case of laryngeal chondrosarcoma manifesting as a swollen mass of 10 x 7 x 6 cm in the infrahyoid and left lateral cervical region. The patient underwent total laryngectomy, thyroidectomy and bilateral neck dissection. A review of the literature on this disease is also reported.     

Renal Cell Carcinoma metastasizing to Larynx: A Case Report

Renal Cell Carcinoma (RCC) is a malignant tumor occurring in 5th-6th decade of life with an increasing incidence reported in the US but stable in Europe. The metastasis of RCC to head and neck region is infrequent and very rarely seen in larynx. Very few cases of RCC metastasizing to larynx are reported in literature. We report a case of RCC in a middle aged male with metastasis to larynx, 7 years after initial diagnosis and nephrectomy. These unusual tumor metastases have unique pathobiology and route of metastasis, and there can be a long interval from initial diagnosis of primary tumor. The diagnosis of metastatic RCC in unusual locations is often not easy. Treatment options include metastasectomy, radiotherapy and systemic chemotherapy but with a poor outcome. A differential diagnosis should always be considered in metastatic head and neck tumors. The need for prompt accurate diagnosis, risk stratification at initial primary diagnosis, surveillance, and long term regular follow up is emphasized. Key words: Metastatic RCC, Laryngeal metastasis, Royal Hospital Oman, Metastatic Ca, metachronous metastasis.     

Lymphangioma of the larynx as a cause of progressive dyspnoea

The following is a case report of a lymphangioma of the larynx in a 16-year-old girl with Down’s Syndrome. The clinical record of the girl, the diagnosis of the tumour and its surgical treatment as well as the postoperative course and the follow-up results are described.     

Primary oat cell carcinoma of the larynx: A case history and literature review

A case of primary oat cell carcinoma of the larynx is described and the literature reviewed. The origin of this rare tumor and the natural history of the disease are discussed. The different treatment modalities carried out so far are described.     

Angiolipoma of the larynx

A rare case of Angiolipoma of the larynx is being reported. The paucity of literature and the interesting clinical features prompted us to report this case.     

An extremely rare case of synchronous occurrence in the larynx of intravascular lymphoma and in situ squamous cell carcinoma

We present the first case of laryngeal intravascular lymphoma coexisting with in situ squamous cell carcinoma. The patient, a 53 years old man, presented with hoarseness starting a year ago and underwent laryngoscopy, which revealed two nodular lesions on his right vocal cord. The histological and immunohistochemical examination of the biopsy specimens established the diagnosis of in situ squamous cell carcinoma coexisting with intravascular lymphoma of T-cell origin. Taking in consideration all the available references, the larynx has not until now been reported as a primary site of involvement of intravascular (angiotropic) lymphomas, nor as a secondary location in the systematic course of this disease. Furthermore no cases have been reported in the literature, concerning the synchronous affection of the larynx by this lymphoma and in situ laryngeal carcinoma, or other type of neoplasm.     

CO2 laser in the treatment of laryngeal synovial sarcoma: a clinical case

Synovial sarcoma is a rare mesenchymal neoplasm that is usually located in the limbs. Its occurrence in the head and neck region, and particularly in the larynx, is exceptional, with only 16 cases reported to date. Two histological variants have been described, a biphasic and a monophasic variant. Immunohistochemistry is determinant in the differential diagnosis between synovial sarcoma and other spindle and biphasic neoplasms. The treatment of choice is conservative surgery with tumor-free margins, while radiotherapy is effective in local control of the disease after recurrence. Chemotherapy is indicated for the treatment of distant metastases. We present a case of monophasic synovial sarcoma of the laryngeal ventricle that was successfully treated with CO2 laser excision and we briefly review the literature on the subject.     

Laryngeal mucormycosis

The mycotic infections of the larynx include histoplasmosis, aspergillosis, actinomycosis, blastomycosis, coccidiodomycosis and sporotrichosis. Mucormycosis has been known as an acute and fulminating fungal infection, described under obvious clinical types i.e. rhinofaciocranial, pulmonary, gastrointestinal or abdominopelvic and cutaneous mucormycosis, but no case of laryngeal mucormycosis could be found in the literature up to date. Further, chronic granulomatous lesions in an otherwise healthy person are infrequent in the case of mucormycosis. Herewith are dealt various aspects of mucormycosis, along with the first reported case of primary localized mucormycosis of larynx presenting as a vocal cord polyp.     

Malignant paraganglioma of the larynx

Paraganglioma of the larynx are rare tumours and only 25 cases have been reported in the world literature. Paraganglioma of larynx are paired superior and inferior laryngeal glomus bodies in association with superior and recurrent laryngeal nerves respectively. The tumours arising from laryngeal glomus bodies appear in subglottic space, in trachea, as a supraglottic mass and as a neck swelling. A case of malignant paraganglioma of the larynx with metastasis to the cervical lymphnodes and lungs have been presented with brief review of literature.     

Adenoid cystic carcinoma of the larynx: a report of four cases and a review of the literature.

Adenoid cystic carcinoma (cylindroma) is a well-recognized tumor that is frequently encountered in the major salivary glands, the lacrimal glands and in the minor salivary glands of the oral cavity and upper respiratory tract. Only 60 cases of adenoid cystic carcinoma have been described arising in the larynx. Four new cases are reported and the literature is reviewed. In the larynx, these tumors arise almost exclusively in the subglottic and supraglottic regions--areas having large numbers of seromucinous glands of the minor salivary gland type. These malignant tumors, whether occurring in the larynx or elsewhere, tend to grow quite slowly with prolonged non-specific symptomatology and protracted clinical course. Despite their slow growth, in a majority of cases, they eventually lead to the death of the patient.     

Late post radiation laryngeal chondronecrosis with pharyngooesophageal fibrosis

Chondroradionecrosis of larynx is a well recognized complication of radiation therapy, which usually occur with in the 1st year. Review of literature shows very few accounts of late radiation induced clinical chondroradionecrosis of the larynx. This condition can mimic a local recurrence and severe and life threatening involvement will require aggressive surgical management as reported in the present case.     

Chondrosarcoma of the larynx after radiation treatment for vocal cord cancer

The case of a 57-year-old man with chondrosarcoma of the laryngeal cartilage is presented, occurring 16 years after radiation treatment for squamous cell carcinoma of the right true vocal cord. Chondrosarcoma of the larynx is an uncommon tumor. The location, grade, and time elapsed from initial treatment make it probably that this patient's chondrosarcoma is associated with his prior radiation treatment. However, it is a rare occurrence, this being the second case reported in the literature.     

Extranodal manifestation of Rosai Dorfman Disease of the nasopharynx

The aim of presenting this case is to highlight the fact that extranodal manifestation of Rosai Dorfman Disease (RDD) without lymphadenopathy was seen in a teenaged girl with recurrent episodes of epistaxis, due to a lobulated mass in the nasopharynx, which mimicked malignancy. This case is a rare presentation because the extranodal manifestation of RDD in multisystem organs are reported in literature, but the nasopharyngeal manifestation without lymphadenopathy is unique. The clinical presentation and surgical management of the case by endoscopic sinus surgery, the aetiopathology, differential diagnosis and review of literature are described here.     

Rare impacted foreign bodies of larynx

This paper presents our experience with three cases of very unusual impacted foreign bodies in larynx and all without any Classical signs and symptoms of foreign body inhalation. Review of literature reveals that these conditions are rare and reported infrequently. Correct diagnosis and adequate approach is necessary as foreign bodies that do not obstruct the airway and which are stuck in place may be relatively asymptomatic but could be life threatening.