Nasal glioma

A case of an extranasal glioma is reported. A brief discussion as to the etiology, clinical manifestations and management of the lesion is made.     

Nasal glomangioma

Glomus tumours have been reported in various sites viz. skin, subcutaneous tissue, muscle and viscera. The involvement of nasal mucosa by this lesion is extremely rare. A rare case of Glomangioma involving nasal mucosa in a 19 year old male presenting as nasal obstruction and painless bleeding is described and the pertinent literature is reviewed.     

Nasal proboscis

A case of Nasal Proboscis is described with a review of literature and the treatment given, because of the rare nature of the congenital anomaly.     

Nasal myiasis

Nasal myiasis is rare in the world, but India being a tropical country the disease is very common and extremely demoralising for the patients. Keeping this in view, the clinical profile of nasal myiasis with special reference to entomological aspects was studied in 13 cases from February 1991 to March 1992. It was found to be common in age group 61– 70 yrs (38.5%). Foetor, maggots in the nose, blood stained nasal discharge, necrotic material and atrophic turbninates were seen in all cames. The major complications were maxillary sinusitis found in all the cases and diffuse cellulitis of face in 69.2% cases. Penetration of fly into the nasal cavity was recalled by 38.4% cases. Treatment consisted of removing the maggots manually after turpentine nasal douche. Larvae were cultured on fresh placenta/tonsil in 8 cases. The fly causing myiasis in this area was identified as chrysomyia bezziana. Use of mosquito net and treatment of the cause was found to be the most effective and easy method of prevention.     

Nasal fractures

Fracture of nasal bones and its often association with other fractures such as Naso-ethmoid complex, zygoma, orbit, etc., require careful assessment for any aesthetic as well as functional impairment. Early diagnosis and treatment is advisable in these cases.     

Nasal hemangiopericytoma

Haemangiopericytoma is rare tumour of vascular tissue. It’s pathological behaviour is variable. It arises from pericytes of Zimmermann. Although one fourth of cases are reported from head and neck region, nasal haemangiopericytoma is very rare. Because of rarity of condition, one case of nasal haemangiopericytoma arising from nasal septum is reported.     

鼻内镜技术用于治疗鼻腔鼻窦恶性肿瘤的临床疗效观察

目的 探讨鼻内镜技术治疗鼻腔鼻窦恶性肿瘤的临床疗效.方法 选取80例鼻腔鼻窦肿瘤患者,40例患者鼻内镜下行手术切除(观察组),根据每个肿瘤类型和部位的不同,确定鼻内镜下手术切除范围.另40例患者行传统手术方法(对照组).比较2组手术时间,术中出血量、术后疼痛视觉模拟评分(VAS),术后焦虑自评量表评分(SAS)、术后并发症和复发率情况.结果 观察组的手术时间和术中出血量均明显少于对照组(P＜0.05);观察组术后视觉模拟评分(VAS)和焦虑自评量表评分(SAS)均明显低于对照组(P＜0.05);观察组的并发症和复发率均低于对照组(P＜0.05).结论 鼻内镜技术切除鼻腔鼻窦肿瘤损伤小、手术时间短、出血量少、术后疼痛少,术后焦虑较轻,术后并发症和复发率低,具有较好临床疗效,值得临床推广应用.     

Nasal endoscopy-evaluation in epistaxis

Epistaxis is generally of two types : one where a cause is recognised ( Local or Systemic ) and the other where the cause is not known. All cases of nose bleeds with no evident cause is customarily categorised into an Idiopathic type. Anterior rhinoscopy ordinarily gives a very limited view of the nose and the probable cause of epistaxis, and this, we feel could he one of the reasons why a proper diagnosis is not always likely. Another problem is the poor localisation of the site of bleeding point. Such cases pose a problem in implementing treatment, as the cause or the site is not easily located. This study tries to venture the exquisite and wide vision provided by the Nasal endoscope. This study also tries to investigate the possibility of reaching the inaccessible bleeding points, to treat them directly. The study was conducted on 60 patients who attended the Out Patient Department and the Indoor ward with complaints of Epistaxis.     

Nasal and antral cholesteotoma

Four interesting cases of nasal cholesteatoma presenting in diffrent ways are reported.     

Nasal and cutaneous diphtheria

A case of nasal and cutaneous diphtheria is presented with a brief review of literature. Whenever cutaneous lesions are present with nasal, facial or laryngeal diphtheria, the lesions should be considered to be cutaneous diphtheria unless proved otherwise.     

Nasal and nasopharyngeal paraganglioma

Paragangliomas of the nasal cavity and nasopharynx should be classified according to the presumed origin from the nasal, jugulotympanic, vagal, or ciliary paraganglion because of the substantial differences in clinical behavior and operative management. This paper presents the ninth published case of a primary nasal paraganglioma and reviews the previously reported cases. Primary nasal paragangliomas are generally localized, although the potential for local invasion is well documented. Malignancy or functional activity has not been described. Complete excision is curative. Jugulotympanic, vagal, and ciliary paragangliomas with extension into the nasopharynx or nasal cavity are typically more advanced at the time of diagnosis and require complete evaluation by computed tomography and arteriography to determine the tumor extent. The operative approach is dependant on the extent of tumor invasion. Irradiation and tumor embolization have been useful for unresectable or partially excised tumors.     

Nasal and sinus endoscopy

One of the most revolutionary changes seen in Rhinology in the recent past is the introduction of the telescope to visulaize hidden areas of the nasal cavity and maxillary sinus and the management of the recurring sinus disease. Narrow and stenotic areas in the anterior ethmoid specially in the infundibulum where frontal and maxillary sinuses drain are the important areas for the detection and cure of infection of the anterior group of the paranasal sinuses. One must clearly understand surgical anatomy of the middle meatus and the ethmoids before resorting to nasal and sinus endoscopic procedures. Nasal and sinus endoscopy combined with computerized tomography helps to locate and know precicisely the extent of basal and sinus disease. Antroscopy has been found very good diagnostic tool for the assessment of maxillary sinus pathology. Plain X-ray of P.N.S. gives only general information of sinuses. G. T. Scan of P. N. S. is more useful for localizing the extent of disease.     

38例鼻腔鼻窦肉瘤治疗回顾

对我院收治的38例鼻腔、鼻窦肉瘤作出回顾性分析,且对其据HE染色的病理切片做出肿瘤的分类和检测,及据1997年UICCGTNM软组织肉瘤进行病理分级.治疗方法为选用6MV的X线+电子束两种混合射线DT65～80Gy放射,术前50～60Gy+鼻腔、鼻窦广泛切除术,鼻腔、鼻窦广泛切除+50～70Gy放疗术3种方法.其结果显示单纯放疗3年生存率为33.3%,5年生存率为0;放疗+手术3年生存率为40%,5年生存率为33.3%;手术+放疗3年生存率为82.6%,5年生存率为58%,由此见手术+放疗对提高病人5年生存率具有积极作用,且软组织肉瘤以高剂量为宜,易采用多次.肿瘤防治杂志,2001,8(特)247-248     

Nasal septum perforation and bevacizumab

The use of targeted/biologic therapies is now commonplace in the treatment of malignant and non-malignant diseases. The novel mode of action of these drugs has resulted in unpredictable and in some cases unexpected side effects. Given the widespread use of bevacizumab and its distinct mode of action, it is important that oncologists report any unexpected adverse events that may be associated with the drug. Herein, we report three cases of spontaneous nasal septum perforation secondary to bevacizumab. We hypothesize an etiology for this rare event and reasons why it is reasonable to rechallenge the patient.