140例面部皮炎斑贴试验结果分析

目的 通过斑贴试验研究面部皮炎的病因与诊断.方法 以标准筛选抗原对140例面部皮炎患者进行斑贴试验.结果 140例患者中98例出现1种或1种以上抗原阳性反应,总阳性率为70%,其中甲醛阳性率最高,达47%,其余依次为硫酸镍、重铬酸钾、夸特、芳香混合物.结论 面部皮炎患者应常规进行斑贴试验,金属制品、化妆品、染料、建材等在引发面部皮炎中起重要作用.     

张家口地区皮炎湿疹患者斑贴试验结果分析

皮炎湿疹是皮肤科常见病和多发病。因其病因复杂,易复发,给患者带来极大的痛苦,因此,了解本地区临床上常见的皮炎湿疹的接触性变应原尤为重要,它可以帮助患者寻找相应接触性变应原,并为该类疾病的预防、诊断和治疗提供了重要参考依据。我科2009年8月至2012年3月对门诊诊断为皮炎湿     

化妆品皮炎斑贴试验探讨

用标准筛选系列抗原及病人各自的可疑化妆品产品，对62名化妆品皮炎进行斑试，探讨用标准系列抗原斑试与可疑化妆品斑试的关系及其应用价值。结果用可疑化妆品斑试阳性检出率明显高于标准筛选抗原斑试阳性检出率（P＜0.05），符合率84．75％。本研究表明：标准系列抗原的斑试与可疑化妆品的斑试相互补充，不能替代，都是诊断化妆品皮炎的重要手段。     

某地区104例皮炎湿疹类皮肤病患者斑贴试验结果分析

目的检测和分析苏州地区皮炎湿疹类皮肤病接触变应原。方法采用瑞典进口"瑞敏牌"斑贴试验试剂盒对患者做斑贴试验,并对试验结果、与发病部位及职业等相关因素进行分析。结果 104例皮炎湿疹患者中有59例出现一种或一种以上阳性反应,阳性率为56.73%;变应原阳性率最高的是硫酸镍;手部皮炎湿疹的阳性率最高,达71.43%,以硫酸镍和芳香混合物阳性率最高,其次为泛发全身的(53.33%),以硫酸镍阳性率最高;教师和厨师的阳性率最高。结论斑贴试验可以明确皮炎湿疹类皮肤病患者的接触性致敏原,有助于该类疾病的诊断、治疗以及预防。     

皮炎和湿疹200例斑贴试验结果分析

皮炎和湿疹是皮肤科常见疾病,其病因复杂,明确致敏原对临床防治有重要意义[1].我科2005年4～12月对200例皮炎、湿疹做斑贴试验,现将结果总结报告如下.     

皮炎和湿疹200例斑贴试验结果分析

皮炎和湿疹是皮肤科常见疾病,其病因复杂,明确致敏原对临床防治有重要意义[1].我科2005年4～12月对200例皮炎、湿疹做斑贴试验,现将结果总结报告如下.     

皮炎湿疹患者124例斑贴试验结果分析

目的 探讨皮炎湿疹类疾病接触性变应原的特点及与不同过敏性疾病、职业之间的关系.方法 采用“百亿”斑贴试验变应原对124例皮炎湿疹患者(面部皮炎63例,手部湿疹17例,脐周皮炎10例,其他部位皮炎湿疹34例)进行皮肤斑贴试验检测.结果 124例患者总阳性率为66.13％.阳性率位居前3位的变应原依次为硫酸镍、氯化氨基汞(白降汞)、橡胶4.两种及其以上变应原阳性者达33.87％.男女之间阳性率比较,差异无统计学意义(x2=0.256,P＞0.05).脐周皮炎患者阳性率为100.00％,而面部皮炎、手部湿疹、其他部位皮炎湿疹患者阳性率比较,差异无统计学意义(x2=0.681,P＞0.05).不同职业与变应原种类之间无明显相关性.结论 该试验结果显示最常见的变应原是硫酸镍、白降汞、橡胶4、香料1和重铬酸钾.斑贴试验有助于明确皮炎湿疹患者的接触性变应原,对预防皮炎湿疹具有重要意义.     

女性面、手部皮炎患者斑贴试验结果分析

目的 探讨女性面、手部皮炎患者的接触性致敏原及特点.方法 对80例女性面、手部皮炎患者进行斑贴试验,并对其结果进行分析.结果 80例女性面、手部皮炎患者中斑贴试验阳性56例(阳性率70％)(不包括胶布过敏及可疑阳性者).阳性变应原前7位从高到低依次为:重铬酸钾28例(35.0％)、氯化钴24例(30.0％)、甲醛与硫酸镍各18例(22.5％)、芳香混合物14例(17.5％)、对苯二胺基质与卡巴混合物各11例(13.7％).结论 女性面、手部皮炎患者斑贴试验阳性率较高,符合斑贴条件者,应尽早做斑贴试验,及时找出致敏原.     

湿疹患者斑贴试验150例结果分析

目的对我院皮肤科湿疹患者的斑贴试验结果进行分析,为临床诊断治疗提供参考。方法选取我院皮肤门诊湿疹患者150例,采用标准筛选抗原的试剂盒对所选患者进行斑贴试验,对20种常见变应原的阳性率进行统计分析。结果通过试验发现150例患者中出现1种以上变应原阳性反应的占81.33%,其中变应原阳性率最高的为硫酸镍,阳性率为14.67%,其次是对苯二胺基质和重铬酸钾,阳性率均为7.33%。结论斑贴试验在分析过敏原方面具有重要的地位和作用,有助于临床预防治疗皮肤类疾病。     

面部激素依赖性皮炎90例临床分析

目的对我院面部激素依赖性皮炎临床治疗进行分析。方法对门诊患者的临床资料进行分析讨论。结果根据本组患者的特点,提出激素依赖性皮炎诊断要点。结论人体一旦对激素产生了依赖性,停药后,原发疾病就会复发或加重,加之继发的副作用,可使患者产生较大的痛苦。为此,正确防治激素依赖性皮炎变得尤为重要。采用综合疗法治疗面部激素依赖性皮炎获得了满意的疗效。     

492例接触性皮炎患者斑贴试验分析

目的明确临床常见变应原及各种变应原和性别的关系。方法采用"瑞敏"斑贴试验变应原中国筛查系列对492例疑诊接触性皮炎患者进行斑贴试验。结果斑贴试验总阳性率81.3%,男女斑贴试验阳性率无显著性差异(P<0.05)。常见致敏原依次为重铬酸钾、硫酸镍、卡巴混合物、氯化钴、芳香混合物、甲醛。8种变应原存在性别分布差异:男性阳性率显著高于女性的变应原有重铬酸钾、卡巴混合物、松香、亚乙基二胺和秋兰姆混合物;女性阳性率显著高于男性的有芳香混合物、对苯二胺基质、夸特15(P<0.05)。结论斑贴试验是帮助接触性皮炎患者寻找变应原的可靠方法。     

安徽地区283例慢性过敏性皮肤病斑贴试验结果分析

目的探讨慢性过敏性皮肤病患者常见的致敏原及其特点,为其防治提供依据。方法应用"瑞敏牌"斑贴试剂盒检测283例慢性过敏性皮肤病患者,对试验数据进行统计学分析和比较。结果 283例患者中有158例对20种致敏原中的1种或2种以上呈现阳性反应,总阳性率为55.83%。阳性率高的前5位过敏原依次为:硫酸镍(20.14%)、甲醛(14.49%)、氯化钴(13.43%)、Cl+Me-异噻唑(12.01%)、芳香混合物(10.95%)等。皮损位于躯干四肢者对甲醛阳性率最高(21.88%),唇炎对松香阳性率最高(10.64%)。性别、年龄间斑贴试验阳性率无明显差异。结论斑贴试验寻找慢性过敏性疾病致敏原简单可靠;不同部位皮损和不同病种的常见致敏原不同。     

氟芬那酸丁酯软膏治疗面部皮炎湿疹疗效观察

目的:观察氟芬那酸丁酯软膏治疗面部皮炎湿疹的临床疗效及安全性.方法:将120例患者随机分为观察组和对照组,每组各60例,分别采用氟芬那酸丁酯软膏和1%丁酸氢化可的松乳膏外涂患处,疗程2周.结果:观察组有效率81.67%,对照组有效率78.33%,2组疗效比较无显著性差异.结论:氟芬那酸丁酯软膏治疗面部皮炎湿疹疗效显著,与1%丁酸氢化可的松乳膏疗效相当.     

Patch test results of the dental personnel with contact dermatitis

Objectives: Dental personnel have high risk of occupational contact dermatitis. The aim of this study is to detect the materials which cause contact sensitization and the frequency of contact dermatitis by using patch tests with European standard series and dental screening series in dental personnel.

Methods: Between August 2008 and July 2009, 461 dental personnel working in Ankara (Turkey) were examined and age, gender, previous history of dermatitis, area of the skin affected and clinical diagnosis were noted. About 198 (43%) of the dental personnel were diagnosed contact dermatitis. Sixty-five of the dental personnel accepted to be patch tested.

Results: Dental technicians, dentists and dental nurses constitute 69.2%, 24.6% and 6.2% of patch tested 65 patients, respectively. Positive reactions to at least one allergen were detected with European standard series at 20% and with dental series at 10.8% among the dental personnel. The most common allergens were nickel sulfate (12.3%), acrylates (6.1%) and para-tertiary-butylphenol-formaldehyde resin (4.6%). The most common acrylate was ethyleneglycol dimethacrylate (3.1%).

Conclusions: We believe our study will be helpful to dermatologists about frequency of contact dermatitis among dental personnel and allergens that cause contact sensitivity for developing new methods to protect the personnel in dentistry against sensitization.     

78例接触性皮炎治疗疗效分析

目的评价氯苯吡胺治疗接触性皮炎的疗效。方法接触性皮炎患者78例,采用口服氯苯吡胺联合999皮炎平外用治疗,疗程1周。治疗第1、3、7天后随访并评价疗效,同时记录下不良反应。结果78例患者治疗1周后,症状和体征均有明显改善。结论采用口服氯苯吡胺联合999皮炎平外用治疗接触性皮炎疗效显著,无不良反应的风险,无使用时间的限制,值得临床应用。     

吲哚美辛肠溶片联用丹参酮胶囊治疗面部皮炎临床疗效和经济学研究

目的：观察吲哚美辛肠溶片联合丹参酮胶囊治疗面部皮炎的临床疗效和安全性。方法：将入选的118例面部皮炎患者随机分为试验组(60例)和对照组(58例),对照组给予口服枸地氯雷他定和外用维A酸软膏,试验组在对照组治疗方案基础上加用吲哚美辛肠溶片和丹参酮胶囊,疗程均为4周。结果：治疗结束后,试验组患者的皮损面积、EASI评分及瘙痒程度(3.16±1.76,2.39±1.13,0.65±0.27)均低于对照组(6.73±2.42,5.87±1.26,1.86±0.42),试验组临床总有效率和复发率分别为78.33%和6.38%,对照组分别为56.90%和24.24%,试验组和对照组平均起效时间分别为(11.53±8.53)天和(20.74±10.82)天,以上差异均有统计学意义(P<0.05)。两组均未发生严重不良反应。结论：吲哚美辛肠溶片联合丹参酮胶囊治疗面部皮炎疗效好,起效快,复发率低,值得临床推广。     

Hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral®) as allergen: experience from a Contact Dermatitis Unit

Introduction: Hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC)—Lyral^® is a widely used synthetic fragrance found in personal care and household products. It is an aldehyde, lipophilic enough to penetrate the skin and is a frequent cause of contact sensitization.

Objective: Describe the frequency of contact allergy to HICC in a Contact Dermatitis Unit, after its inclusion in baseline patch test series.

Methods: A retrospective study including all patients submitted to patch test, from January 2007 to December 2009.

Results: Over a 3-year period, 629 consecutive patients were patch tested. The frequency of positive reactions to HICC was 2.7% (17/629). Of the positive patients, 35% (6/17) gave a history of atopy, 58.8% (10/17) had eczema on the face and neck, 23.5% (4/17) on the hands, 23.5% (4/17) in the axillae, 17.6% (3/17) on the trunk and 6% (3/17) had generalized eczema. All patients were patch positive for more than one allergen: all (17/17) positive to fragrance Mix 2 (FM2); 47% of the patients (8/17) positive to fragrance Mix 1 (FM1); and 23.5% of the patients (4/17) positive to Balsam of Peru. In 94% (16/17) of cases, the reaction was judged to be of current relevance.

Discussion: The frequency of positive reactions to HICC of 2.7% found in our population is according to what is described in several European reports, where HICC is still widely used as a fragrance ingredient. In contrast, in North America, the prevalence is lower. All the patients were positive also to FM2. The association found between reactions to FM1 and HICC is also commonly reported and could represent a concomitant sensitization following increased exposure to fragrance allergens. These data confirm the importance of HICC introduction in the baseline patch test series.     

针灸配合推拿、闪罐治疗周围性面瘫120例疗效观察

目的:观察针灸配合推拿、闪罐治疗周围性面瘫的疗效.方法:将240例周围性面瘫患者随机分为2组,治疗组120例用针灸、推拿、闪罐治疗.对照组120例单独用针灸治疗.结果:治疗组明显优于对照组(P＜0.05).结论:针灸、推拿、闪罐治疗可明显提高该病的痊愈率.     

32例引起严重皮炎反应的药物剖析

OBJECTIVE To help the doctors recognise and treat the medicine caused disease by the retrospective analysis of the severe medicine caused dermatitis.METHODS From Janurary 2005 to December 2006,the data about the patients condition,suspected medicine,and t