共查询到20条相似文献,搜索用时 15 毫秒
1.
Kobayashi A Yamaguchi T Ishihara T Tadenuma H Nakamura K Ohshima T Sakaue N Baba T Yoshikawa M Saisho H 《Japanese journal of clinical oncology》2004,34(11):696-699
We report the case of a 53-year-old female who was admitted for sudden abdominal pain. Her right kidney was resected in 1993 due to renal cell carcinoma. Abdominal computed tomography performed in September 2002, while she was placed under observation, revealed a tumor 40 mm in size that extended from the head to the body of the pancreas. Abdominal ultrasonography on admission indicated retention of ascites, and the aspirated ascites was bloody. Based on this result, spontaneous rupture of a pancreatic tumor was strongly suspected. On abdominal contrast-enhanced computed tomography, multiple tumors were clearly visualized in the pancreas. Angiography revealed high-density tumor in the early arterial phase. The results of endocrinological tests were normal. Accordingly, the patient was diagnosed with multiple pancreatic metastases of renal cell carcinoma, and total pancreatectomy was performed. Histopathologically, the tumor resected was clear cell carcinoma and corresponded to the renal cell carcinoma resected in 1993. This is a rare case of pancreatic metastasis of renal cell carcinoma that resulted in spontaneous rupture 9 years after nephrectomy. 相似文献
2.
Regressions of metastases following nephrectomy for renal cell carcinoma are rare. Most reported cases have involved pulmonary metastases. Hormonal and immunological mechanisms have been postulated. A case is described of a pulmonary metastasis which regressed after nephrectomy and which failed to recur despite the later appearance of new sites of pulmonary metastases. The literature is reviewed. 相似文献
3.
Osteolytic characteristics of bone metastasis from renal cell carcinoma were morphologically and biochemically investigated. First, undecalcified ground sections of bone metastases were made from four patients with renal cell carcinoma. Second, renal cell carcinoma cell line (RCC-K1) was established from one of the four patients, and its effect on bone resorption in vitro was examined. Marked proliferation and activation of osteoclasts around the tumor cells was histologically demonstrated. Conditioned medium from the RCC-K1 cells contained potent bone-resorbing activity in vitro. The activity was reduced to basal level by calcitonin, but was not blocked by indomethacin. The activity was lost after dialysis (MW cutoff 3500), while it was retained after 2 weeks of storage. Levels of prostaglandin E2 and 1,25-dihydroxyvitamin D of the RCC-K1-conditioned medium were insufficient to cause bone resorption in vitro. The conditioned medium did not stimulate cAMP accumulation in rat osteoblastic cells. These results suggest that renal cell carcinoma causes bone destruction through the stimulation of osteoclasts by locally secreting an unknown humoral factor or factors. 相似文献
4.
A 78-year-old Japanese man with chronic liver disease developed hypervascular liver tumors accompanied by marked elevation of alphafetoprotein value (the highest level; 26200 ng/ml) and pathologic fracture of the femur. After an operation for the fracture followed by gastrointestinal bleeding and repeated transfusions of blood, the tumors disappeared with normalization of the alpha-fetoprotein level, and the radiolucent area around the fracture site of the femur became consolidated. The necrotic tissue responsible for the fracture histologically showed an appearance of hepatocellular carcinoma. The patient survives 62 months after the initial increase in alpha-fetoprotein level. This is a case of spontaneous regression of both hypervascular liver tumors which are highly suggestive of hepatocellular carcinoma and their metastasis. 相似文献
5.
Iwasaki M; Furuse J; Yoshino M; Moriyama N; Kanemoto H; Okumura H 《Japanese journal of clinical oncology》1997,27(4):278-281
We report a hepatocellular carcinoma that appeared to undergo spontaneous
regression twice. On June 5, 1995, two hepatocellular carcinomas were
detected by ultrasonography in a 72-year-old woman. On July 1, 1995, the
tumor in the lateral segment had increased in size from 2.0 cm to 3.2 cm in
27 days, and the level of alpha-fetoprotein (AFP) had increased from 743 to
1300 ng/ml. On September 22, 1995, one tumor appeared as a typical
hypervascular lesion on contrast-enhanced computed tomography. It was 3.9
cm in size and located in the posterior segment. The other was a 3.9-cm
cystic mass located in the lateral segment. The tumor in the posterior
segment was treated with an emulsion of epirubicin and lipiodol
administered via the posterior branch of the right hepatic artery and
percutaneous ethanol injection. The tumor in the lateral segment was kept
under observation because it was avascular, had regressed to 2.0 cm in
size, and the patient's AFP level had decreased to 237 ng/ml by December 5,
1995. By February 21, 1996, the AFP level had increased again to 105,340
ng/ml, and by March 22, 1996, the latter tumor had increased in size to 3.8
cm. However, it later regressed again to 1.6 cm, and the AFP level
decreased spontaneously to 7 ng/ml. From the changes in the
contrast-enhanced computed tomographic images, and the level of AFP, we
cannot rule out the possibility that the spontaneous regression might have
been caused by the tumor's rapid growth.
相似文献
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A 64 year-old man with a metastatic clear-cell renal carcinoma experienced low intestinal bleeding. The endoscopy revealed a polypoid mass in the left colon which proved to be a metastasis of the renal carcinoma. This is an uncommon cause of intestinal hemorrhage, and a rare localization of metastatic deposits. 相似文献
8.
This is the first case report of a patient with oat cell carcinoma of the lung with scalene node metastasis who, without treatment, is alive 19 years after the original diagnosis was made by biopsy. Seven years before the publication of this report, and at the age of 66 years, he underwent coronary bypass surgery and there was no gross evidence of malignancy present. 相似文献
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10.
Pancreatic metastasis from renal cell carcinoma extending into the main pancreatic duct: a case report 总被引:2,自引:0,他引:2
Yachida S Fukushima N Kanai Y Nimura S Shimada K Yamamoto J Sakamoto M 《Japanese journal of clinical oncology》2002,32(8):315-317
While metastasis to the pancreas is uncommon, it may occur from renal cell carcinomas (RCCs). We here present a case of pancreatic metastasis from RCC extending into the main pancreatic duct (MPD) in a 66-year-old Japanese man. The patient had a history of RCC treated with a radical nephrectomy 17 years previously and was found to have a mass approximately 2 cm in diameter in the body of the pancreas on radiological images. The patient was suspected of having pancreatic metastasis from RCC and underwent a distal pancreatectomy with splenectomy. Histologically, the tumor consisted of cells arranged in trabecular and alveolar structures with clear or eosinophilic granular cytoplasm, compatible with a metastatic RCC. The pancreatic tumor extended into the MPD with the stream of pancreatic juice. This condition is similar to RCC extension into the renal vein and the inferior vena cava. In conclusion, although extension into the MPD may be rare, such a growth pattern may be characteristic of metastases from RCCs. 相似文献
11.
The authors report a case of a man who developed soft tissue metastasis to the thigh from pulmonary carcinoma. In the preoperative staging, computerized tomograms and magnetic resonance imaging allowed to identify and characterize the features of soft tissue masses; these studies, however, must be always completed with needle (tru-cut) or incisional biopsy. 相似文献
12.
A case of renal cell carcinoma with heterotopic bone formation occurring in a female aged 55 years has been reported. There was no haematuria and the morphological picture showed only ossified stroma and no sarcomatoid appearance. 相似文献
13.
We report the case of a patient with a metastatic tumor in the right ventricle, apparently derived from a transitional cell
carcinoma. The patient presented with severe hypoxemia as a result of right-to-left shunt due to the position of the tumor
and a patent foramen ovale. The clinical course of this case is presented and the pathophysiology of the physiological effects
caused by the metastatic tumor is discussed. The literature concerning cardiac metastases is reviewed. 相似文献
14.
Liver metastases are an uncommon cause of spontaneous bleeding compared with primary benign/malignant liver lesions. Since metastatic lesions tend to maintain the vascular characteristics of the primary tumor, some metastases have a greater proclivity for hemorrhage into the host organ than others. We describe the clinical and computed tomography (CT) features of a patient previously treated for nonkeratinizing small cell squamous carcinoma of the cervix uteri. As the metastatic rupture was diagnosed while still intraparenchymal and subcapsular, with minimal peritoneal reaction, the patient's outcome was favorable. 相似文献
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Operative treatments for bone metastases were performed in 7 patients with an advanced renal cell carcinoma. Spinal instrumentation using a Harrington's rod and Luque's wire was the method employed in 4 cases as the initial treatment. In one other case, an anterior fusion by an autologus bone transplantation was used, followed by a posterior fusion. In the 2 remaining cases an endoprosthetic replacement for a metastasis in the right femur and a transplantation of a Kotz's knee joint was done for a metastasis in the left tibia, respectively. In 5 patients with vertebral column lesions, the stabilization of spinal instability was effected by the spinal instrumentation. Three patients with vertebral metastases recovered sufficiently to walk by themselves. This beneficial result was invaluable from the viewpoints of physiotherapy and nursing care. 相似文献
18.
An unusual case of bilateral synchronous parotid metastases from renal cell carcinoma presenting seven years after nephrectomy is reported. The patient underwent bilateral superficial parotidectomy and is alive free of disease three and half years after the metastatectomy. 相似文献
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Hoshi S Satoh M Ohyama C Hiramatu M Watanabe R Hagisawa S Endo M Arai Y 《International journal of clinical oncology / Japan Society of Clinical Oncology》2003,8(2):0113-0117
Sarcomatoid renal cell carcinoma (SRCC) is associated with an aggressive course, high incidence of bone metastasis, and an
extremely poor prognosis. There are a few case reports concerning the effectiveness of chemotherapy on metastasis in SRCC.
To our knowledge, however, there are no reports describing its effectiveness on bone metastasis. We report a 22-year-old woman
with an 8-cm × 7-cm left renal mass. Left nephrectomy was done. The pathological diagnosis was SRCC, INF-β, pT3aN2. Although,
she received continuous infusion of interferon α-2a (INFα-2a) and interleukin-2 (IL-2) as adjuvant therapy, liver metastasis
appeared 2 months later. Resection of the liver metastasis was done. After resection of the metastasis, multiple bone metastases
appeared, in both humeri, the left chest wall, the left fourth rib, and the left iliac bone. The patient was treated with
gemcitabine, 1000 mg/m2 (days 1, 8), docetaxel 80 mg/m2 (day 1), and carboplatin 300 mg/m2 (day 1). A computed tomography (CT) scan after the first cycle revealed that the multiple osteolytic bone tumors had significantly
decreased in size. Her ability of daily life (ADL) improved and this continued for almost 2 months. A second course of chemotherapy,
with gemcitabine and IL-2 was given, but it was ineffective, and the patient died approximately 16 months after the initial
diagnosis of SRCC. Combination chemotherapy with gemcitabine, docetaxel, and carboplatin was effective for the bone metastasis
of SRCC.
Received: August 21, 2002 / Accepted: December 10, 2002
Correspondence to:S. Hoshi 相似文献