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张鹏 《国际医学放射学杂志》2012,35(6):523-525
多发性硬化（MS）是由炎性脱髓鞘病变引起的中枢神经系统常见疾病之一。MS病人会出现不同程度的认知功能障碍。近年来出现的扩散加权成像、磁化传递成像、磁共振波谱、磁敏感加权成像和功能磁共振成像等MRI新技术在显示MS特异性征象、进行定量研究、诊断和鉴别诊断、监测病程和疗效以及判断预后等方面取得了重大进展。 相似文献
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磁共振弹性成像是一种能够无创地定量评估组织机械属性的检查手段,能够为临床提供有价值的诊断信息.近年来,磁共振弹性成像已逐步在临床中得到应用,现就磁共振弹性成像在肝脏检查中的应用价值及前景予以综述. 相似文献
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软组织的弹性(硬度)变化与其病理过程有着密切的联系。磁共振弹性成像(MRE)是一种无创评估软组织生物力学属性的MR成像新技术,可以通过定量测量软组织的弹性信息,为前列腺疾病的检出和诊断提供客观依据。近年来MRE在前列腺疾病方面的应用已成为研究热点。主要阐述MRE的成像原理以及在前列腺疾病中的应用进展。 相似文献
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Magnetic resonance imaging (MRI) has emerged as an essential tool of multiple sclerosis (MS) diagnosis and has opened up completely new prospects in MS research and treatment trials. It is a sensitive method that gives direct evidence of tissue pathology and has greatly increased our knowledge of MS. In clinical work, MRI is used to confirm and exclude the diagnosis of MS. The international recommendation is that every suspected MS patient should undergo at least one brain MRI. T2-weighted images are the standard tool in clinical work, and functional imaging methods are mainly used in MS research. The subtypes and the course of the disease cause variation in MRI findings. Here, we present a general overview of MR findings in MS. 相似文献
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Acute disseminated encephalomyelitis and multiple sclerosis: magnetic resonance imaging differentiation 总被引：2，自引：0，他引：2
The study was undertaken to compare the MR imaging features of acute disseminated encephalomyelitis (ADEM) and multiple sclerosis (MS) in a country with a high prevalence of ADEM. Magnetic resonance scans from 33 patients diagnosed clinically with MS (14 patients) or ADEM (19 patients) were reviewed concurrently by two radiologists blinded to the clinical diagnosis. The size, site, morphology and pattern of brain and spinal cord involvement were recorded and the MR imaging diagnosis was compared with the clinical diagnosis. The MR imaging findings matched with the clinical diagnosis in 11 of 14 patients with MS (sensitivity = 78.6%), and with the clinical diagnosis in 15 of 18 patients with ADEM (sensitivity = 78.9%). Three patients had non-specific findings and in a further three patients discordant imaging features were present. One patient with imaging features typical of Balo's concentric sclerosis was diagnosed clinically as suffering from ADEM. In a country with a high prevalence of ADEM, the majority of patients with ADEM and MS can be differentiated on MR imaging. 相似文献
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Lycklama à Nijeholt GJ Uitdehaag BM Bergers E Castelijns JA Polman CH Barkhof F 《European radiology》2000,10(2):368-376
We examined the value of spinal cord magnetic resonance imaging (MRI) in the diagnostic work-up of multiple sclerosis (MS).
Forty patients suspected of having MS were examined within 24 months after the start of symptoms. Disability was assessed,
and symptoms were categorized as either brain or spinal cord. Work-up further included cerebrospinal fluid analysis and standard
proton-density, T2-, and T1-weighted gadolinium-enhanced brain and spinal cord MRI. Patients were categorized as either clinically
definite MS (n = 13), laboratory-supported definite MS (n = 14), or clinically probable MS (n = 4); four patients had clinically probable MS, and in nine MS was suspected. Spinal cord abnormalities were found in 35
of 40 patients (87.5 %), consisting of focal lesions in 31, only diffuse abnormalities in two, and both in two. Asymptomatic
spinal cord lesions occurred in six patients. All patients with diffuse spinal cord abnormality had clear spinal cord symptoms
and a primary progressive disease course. In clinically definite MS, the inclusion of spinal imaging increased the sensitivity
of MRI to 100 %. Seven patients without a definite diagnosis had clinically isolated syndromes involving the spinal cord.
Brain MRI was inconclusive, while all had focal spinal cord lesions which explained symptoms and ruled out other causes. Two
other patients had atypical brain abnormalities suggesting ischemic/vascular disease. No spinal cord abnormalities were found,
and during follow-up MS was ruled out. Spinal cord abnormalities are common in suspected MS, and may occur asymptomatic. Although
diagnostic classification is seldom changed, spinal cord imaging increases diagnostic sensitivity of MRI in patients with
suspected MS. In addition, patients with primary progressive MS may possibly be earlier diagnosed. Finally, differentiation
with atypical lesions may be improved.
Received: 21 April 1999; Revised: 3 August 1999; Accepted: 7 August 1999 相似文献
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F. Barkhof A. J. Thompson L. Kappos J. J. P. Nauta T. Yousri I. Berry G. Scotti B. Appel P. S. Tofts D. H. Miller 《Neuroradiology》1993,35(5):362-366
The unique sensitivity of magnetic resonance imaging (MRI) in detecting disease activity in multiple sclerosis (MS) and the objective nature of the information obtained suggest that MRI will be a useful and reliable way of monitoring treatment trials. There is a need to develop an appropriate database which would provide a standardised means of assessment, not only of MRI, but also of essential clinical information. As part of the program of Concerted Action in Multiple Sclerosis, funded by the Commission of the European Community (CEC), we have developed a database for recording serial brain MRI results. The database consists of core, entry and follow-up sections. Both entry and follow-up parts are subdivided into clinical, MR system and MRI data. We expect that the use of this database will maximise efficiency of MRI monitoring in MS treatment trials, particularly in multicentre studies. 相似文献
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