强脉冲光联合Nd:YAG激光治疗黄褐斑疗效观察

目的:探讨强脉冲光联合Nd:YAG激光治疗黄褐斑的疗效。方法:60例患者按治疗方法不同分成3组:强脉冲光组、Nd:YAG激光组、联合组（强脉冲光联合Nd:YAG激光组）,每组20例患者,观察3组患者疗效和副作用。结果:3组之间疗效两两比较采用Mann-Whitney秩和检验,强脉冲光组和激光组疗效无显著差异,而联合组疗效显著好于强脉冲光组（Z=7.123, P=0.024）和激光组（Z=6.024, P=0.030）。3组患者治疗后均无出现色素沉着加重、色素脱失病等不良反应。强脉冲光组和激光组的满意度无显著差异,而联合组的满意度显著好于强脉冲光组（Z=7.361, P=0.029）和激光组（Z=6.831, P=0.027）。结论:强脉冲光联合Nd:YAG激光治疗黄褐斑是一种安全有效的治疗方法,值得临床推广。     

宫腔镜下Nd:YAG激光治疗子宫内疾病78例分析

目的 :评价宫腔镜对子宫内疾病的诊断价值和采用Nd :YAG激光治疗子宫内疾病的效果。方法 :对 78例子宫内疾病 (包括子宫内粘连、子宫粘膜下肌瘤、子宫纵隔、子宫粘膜息肉、宫颈息肉及宫颈管囊肿 )采用宫腔镜进行诊断 ,并用Nd :YAG激光进行治疗。结果 :宫腔镜诊断子宫内疾病的准确率高于超声诊断及放射诊断。采用Nd :YAG激光治疗的一次性成功率为 97.43 %。手术时间为 2 0 5 5分钟 ,平均 3 5 .7± 18.5分钟。无明显并发症。术后 1 3个月随访 2例病人有残留的粘连带及纵隔组织而进行二次手术。其余患者均恢复正常。 8例患者 (有生育要求者 )在一年内妊娠。结论 :对于子宫内疾病宫腔镜有较高的临床价值 ,采用Nd :YAG激光治疗具有更简便、安全、疗效确切等优点 ,具有广泛的应用前景     

Nd：YAG激光治疗鼻中隔血管瘤临床体会

本文报道采用Ｎｄ：ＹＡＧ激光治疗鼻中隔血管瘤３１例，一次治愈率９０％，二次治愈率１０％，总有效率达１００％，该方法操作简便，治疗彻底，伤口恢复快。     

氩激光治疗Nd：YAG激光性溃疡

在以Ｎｄ：ＹＡＧ激光治疗自己肉、黄色瘤等胃粘膜病变时，均可引致激光性溃疡。作者以氩激光作局部照射治疗共１０４例１４０处激光性溃疡，２周愈合率为６２％，３周为１００％，且无复发病例。     

KYP型Q开关倍频Nd：YAG激光治疗太田痣72例的护理体会

目的：探讨KYP型Q开关倍频Nd：YAG激光治疗太田痣护理体会。方法我科于2008年10月~2014年8月应用KYP型Q开关倍频Nd：YAG激光治疗太田痣患者72例,回顾性分析通过患者的积极配合和治疗过程中精心的护理。结果取得显著疗效。结论手术前后的护理,及时的沟通解决,缩短了恢复时间,减少了并发症,大大增加了患者的满意度。     

Nd：YAG激光治疗常年性鼻炎疗效观察

我院自１９９６年１０月～１９９９年８月使用ＪＣＷ－ＩＶＢ型Ｎｄ：ＹＡＧ激光器对１６２例常年性鼻炎患者的双侧下鼻甲及鼻兵进行烧灼治疗。结果显示。显效１３４例（８２．６％），有效２５例（１５．５％），无效３例（１．８９％），总有效率达９８．１４％。表明Ｎｄ：ＹＡＧ激光治疗常年性鼻炎效果显著。     

Nd：YAG激光治疗常年性鼻炎274例

本文报道采用Ｎｄ：ＹＡＧ激光点状凝固治疗常年性鼻炎２７４例，痊愈率达６６．８％。     

内镜下Nd∶YAG激光治疗喉乳头状瘤临床分析

目的:探讨内镜下Nd∶YAG激光治疗喉乳头状瘤的临床疗效。方法:采用内镜引导下Nd∶YAG激光照射治疗成人喉乳头状瘤62例。其中纤维喉镜引导55例,支撑喉镜引导7例。结果:术后随访3～13a,58例治愈,4例复发后再次行激光治疗后治愈。结论:Nd∶YAG激光能根治喉乳头状瘤。可以多次治疗,最大限度维持病人喉部的生理功能。     

Nd:YAG laser radiation modifies the proteolytic resistance of rat liver tissue proteins

Central Research Laboratory, Department of Laryngo-Otorhinology, Academician I. P. Pavlov First Leningrad Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR N. P. Bekhtereva.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 111, No. 2, pp. 217–219, February, 1991.     

A histochemical study of the regeneration process after injury by pulsed Nd:YAG laser irradiation of root canals

Histological changes of rat dental pulp cells were followed after injury. The regeneration process after 3, 6 and 10 days was monitored. Mandibular incisors were irradiated with a pulsed Nd:YAG laser at 2 W and 20 pulses per sec (pps) for 5 sec and the pulp was examined histologically and immunohistochemically for TGF-beta1. Eruption of the developing tooth was disturbed for a short period only. Rapid formation of osteodentin was observed. After 3 days, a zone of fibrodentin matrix as well as newly formed vessels were found. Afterwards, regenerative dentin formation was observed accompanied by the formation of a layer of odontoblast-like cells in the damaged area. Immunohistochemical staining of TGF-beta1 showed that positivity was present in small tissue areas beneath the mantle dentin, the zone of fibrodentin matrix and odontoblast-like cells. These results indicate that pulsed Nd:YAG laser irradiation of rat incisor pulp induces formation of osteodentin, and TGF-beta1 plays a role during regeneration.     

Enhancement of Transdermal Drug Delivery by ns Q-swithed Nd ：YAG Laser-induced Pressure Wave

A non-invasive laser enhancing transdermal drug delivery technique has been investigated. The second harmonic wavelength of 532 nm of a Q-Switched Nd：YAG laser with pulse duration of 15 ns was used to irradiate on a black polyethylene sheet covering on the surface of the drug solution, and hence produced pressure waves in the solution. Porcine skin and Rhodamine B were used as skin model and reagent respectively. Fluorescence microscope was employed to examine the mechanisms of drug delivery via the skin samples after laser treatment. The experiment revealed that the penetration depth of Rhodamine B under the illumination of laser increased with the energy density of the laser beam. After 20 laser shots at laser energy density of 70 m J/cm^2, the penetration depth reached 440 μm in 30 minutes, which was about three times as that without laser illumination. One possible explanation was that laser-induced pressure waves formed microchannels in the stratum corneum of the skin tissue. These microchannels provided much more effective paths for infiltration of Rhodamine B through the SC than follicular and intercellular paths. The drug solution diffused into the SC under the concentration gradient through the channels.     

Nd:YAG温热疗法与Ar+激光PDT联合对小鼠S180肉瘤DNA含量的影响研究

目的：本文研究了Nd：YAG激光温热疗法与Ar~＋激光光动力学疗法联合对小鼠S_180．肉瘤DNA含量的影响。材料与方法：实验分为激光温热疗法组、Ar~＋激光光动力学组、联合作用组及对照组等四级。激光温热疗法用Nd：YAG激光照射肿瘤,功率密度约为424mW／cm~2,控制肿瘤边缘温度为43℃照射30min;Ar~＋先动力学疗法为激光照射前24小时小鼠腹腔注射HpD（10mg小kg）,以功率为150mW／cm~2的Ar~＋激光照射15min,联合作用为Ar~＋激光先动力学疗法后立刻行激光温热疗法。结果：在所选定的剂量下,联合作用组的肿瘤DNA含量最小。结论：联合作用对肿瘤的抑制途径之一是对肿瘤细胞中DNA光敏作用。     

用Nd：YAG激光消融家兔实验性心律失常的初步研究

本文介绍一种自行设计的封闭式激光——电极导管及其物理基础实验和离体动物心脏实验的结果。结果表明,间接激光辐射心肌组织损伤小,没有产生组织穿孔。用眼镜蛇毒诱发10只家兔的心律失常模型,以4～12J能量的Nd:YAG激光消融,结果是治疗组与对照组心律恢复正常时间有显著差异(P相似文献   

激光泪道成形术治疗泪道阻塞的临床观察

目的 观察激光泪道成形术治疗泪道阻塞的效果及复发病例再次激光联合插管治疗的效果。方法 采用Nd：YAG激光泪道成形术治疗泪道阻塞102例。132眼。对复发病例。再次行激光联合插管治疗。结果 113眼一次治愈，有效9眼。术后10眼复发，再次行激光联合插管治疗，7眼治愈，3眼未愈。本组总治愈率90．9％，有效率97．7％。结论 Nd：YAG激光泪道成形术治疗泪道阻塞操作简单，安全有效，复发病例联合插管治疗可以提高治愈率。     

Nd：YAG泪道激光成形术治疗泪道阻塞的体会

目的 探讨应用泪道激光治疗泪道阻塞的方法及疗效。方法 应用Nd：YAG泪道激光仪按泪道探通方法连续击射阻塞部位。用抗生素和丝裂霉素C混合液冲洗畅通后植入义管，每周冲洗一次，1月后拔管。结果共治疗53例60眼，随访1～3月。治愈57眼占95％，好转2眼占3．33％，无效1眼仍有溢脓，1月后行泪囊鼻腔吻合术治愈。结论 激光泪道成形术治疗泪总管、鼻泪管阻塞及泪囊炎，方法简单、疗效满意。