文科类硕士研究生心理健康状况与社会支持的关系

目的了解文科类硕士研究生的心理健康状况及其与社会支持之间的关系,为学校的心理干预提供理论依据。方法采用症状自评量表(SCL-90)和社会支持量表(SSRS)对重庆某高校350名文科类硕士研究生进行问卷调查。结果文科类硕士研究生在躯体化、强迫、恐怖、精神症状方面得分高于西部地区在读硕士研究生,在敌对和其他症状方面得分低于西部地区在读硕士研究生(P<0.05)。研究生二年级学生的SCL-90总均分及各因子得分均高于研究生一年级学生(P<0.05)。男性在客观支持、支持利用度方面得分低于女性(P<0.05)。心理健康总均分与各因子得分与客观支持、支持利用度、支持总分呈负相关(r=-0.114~-0.256)。结论文科类硕士研究生心理健康状况与社会支持之间存在相关性,较多的社会支持有利于改善文科类硕士研究生的心理健康状况。     

医学硕士研究生新生不同年龄段心理健康状况调查分析

目的调查分析不同年龄段医学硕士研究生新生心理健康状况,为有效做好研究生心理健康教育工作提供理论依据.方法采用症状自评量表(SCL-90)进行调查,使用EpiData3.0软件建立数据库,应用SPSS进行数据处理和统计分析.结果该医学院硕士研究生新生只有附加因子得分高于我国成人常模(P=0.002);20～25岁与26～30岁的硕士研究生在躯体化(P=0.012)、强迫症状(P=0.003)、人际敏感(P=0.021)、恐怖(P=0.016)、偏执(P=0.003)、精神病性(P=0.023)这6个因子得分上有统计学意义.结论 26～30岁的硕士研究生心理状况比20～25岁的硕士研究生良好,高校应有针对性的对不同年龄段的研究生进行心理健康教育.     

地方大学生入伍干部学员心理健康状况和个性特征分析

目的:评价地方大学生入伍干部学员的整体心理健康状况、个性特征及心理健康与个性因素的关系. 方法:采用症状自评量表(SCL-90)、艾森克个性问卷(EPQ)及自编的"干部学员基本情况调查表"对414名地方大学生入伍干部学员进行整群抽样、现状研究.问卷由学员自行填写独立完成. 结果:干部学员心理健康问题(SCL-90因子分≥3)检出率为1.0%～7.7%,其主要心理健康问题为偏执、人际敏感、抑郁、敌意和强迫倾向. 其整体心理健康水平高于地方大学生和军校学员,与普通军人相比略有差异. 干部学员SCL-90各因子分与EPQ的E,L维度分呈负相关,与P,N维度分呈正相关. 结论:干部学员的心理健康状况良好. 其人格特质与心理健康状况相关.     

医务人员个性特征与心理健康相关性研究

目的 研究医务人员个性特征与心理健康的关系,为有针对性的对医务人员开展心理健康教育和有关部门在制定相关政策时提供依据和参考.方法 用症状自评量表(SCL-90)和艾森克个性问卷(EPQ成人型)对东莞市厚街镇644名医务人员进行心理健康状况调查.结果 医务人员SCL-90各因子中躯体化、人际关系、恐怖、偏执、精神病性因子与中国常模相比差异有统计学意义;EPQ评分P、E、N及L分与中国常模相比差异均有统计学意义;EPQ量表的N分和P分与SCL-90各因子分存在正相关关系;有明显心理健康问题者的N分和P分均较高:不同个性类型明显心理健康问题的检出率间的差异有统计学意义,检出率从高到低顺次的个性类型为内向不稳定型、外向不稳定型、外向稳定型和内向稳定型.结论 医护人员心理卫生水平总体较好,其个性特征与心理健康状况关系密切,具有神经质倾向、精神质倾向、性格内向的个性特征者容易出现不良心理体验,应重视和关注医务人员的心理健康问题.     

医学硕士研究生心理健康现状调查分析

目的 了解医学硕士研究生的心理健康状况,为提高医学研究生心理素质及开展心理健康教育提供依据。方法 采用贝克焦虑量表(BAI)、流调用抑郁自评量表(CES-D)、症状自评量表(SCL-90)等调查工具对309名医学研究生进行心理测试。结果 少数医学硕士研究生存在焦虑阳性的症状,占调查人数的0.97%;肯定有抑郁症的学生占调查人数的8.74%;以总分160分为临界值,有轻度以上心理问题的16人(5.18%);以10个因子中任一项因子分≥2作为轻度心理问题作为检出标准,有轻度心理问题的研究生占调查人数的14.56%。我校医学硕士研究生SCL-90各因子得分均低于全国青年常模组的水平,差异具有统计学意义(P＜0.001)。结论 我校医学硕士研究生总体心理健康状况良好,但少数学生存在轻度的心理健康问题。     

军校医学研究生心理健康状况和个性特征的分析

目的 :评价军校研究生入学后的整体心理健康状况、个性特征及心理健康状况与个性的关系 .方法 :采用症状自评量表 (SCL 90 )、艾森克个性量表 (EPQ) ,流调中心用抑郁量表 (CES D)对 1 98名新入学的某军校医学硕士研究生 ,进行整群抽样、现况研究 .问卷由学生自行填写独立完成 .结果 :SCL 90各项指标中男性研究生阳性项目均分高于女性研究生(P <0 .0 5 ) .在EPQ量表评分中男性研究生的P值评分高于女性 (P <0 .0 1 ) ,女性研究生的L值评分高于男性研究生 (P<0 .0 1 ) .在自我评价性格类型 (A组 :内向型 ,B组 :中间型 ,C组 :外向型 )不同的研究生中SCL 90的各项指标的评分均是A组最高 ,其中人际关系敏感和精神病性因子的评分与B组和C组差异显著 (P <0 .0 5 ) .在A组人群中有 2 2 .9%的抑郁评分大于 2 0分 ,而在B组和C组只有 8.5 %和 6 .1 %的研究生抑郁评分大于 2 0分 .有心理阳性症状的研究生在A ,B ,C组中所占的百分比分别是 31 .4 % ,2 2 .2 %和 1 8.2 % .结论 :性别因素不是影响医学研究生心理健康状况的主要因素 ,研究生的个性特征影响着研究生的心理健康状况     

231名硕士研究生心理健康状况调查分析

目的:调查研究当前硕士研究生群体的心理健康状况。方法:采用症状自评量表(SCL-90)对231名硕士研究生进行测试。结果:硕士研究生心理症状筛查阳性率高达43.70%;与全国成人常模比较,在躯体化、抑郁、焦虑、敌对、恐怖、偏执、精神病性等几个因子上的得分显著高于常模;不同年龄、不同年级、不同婚姻状况、不同工作经历的硕士研究生心理健康状况有显著性差异。结论:当前硕士研究生存在更多的心理健康问题。     

医学研究生心理健康调查

目的:探讨医学研究生心理健康状况。方法:用SCL-90量表对新疆医科大学研究生学院的441名在读硕士研究生进行测试,结果:(1)与全国常摸相比,除精神病性因子外,其他所有因子的数值均比全国常模低(P&lt;0.05)。(2)男生的SCL-90的躯体化、人际关系和抑郁因子分值明显高于女生,而强迫因子分值低于女生,差异有统计学意义(P&lt;0.05)。(3)研一学生的SCL-90的10项因子中,除抑郁因子外,其余9项因子分值均高于研二和研三学生,而抑郁因子分值低于研二和研三学生,差异有统计学意义(P&lt;0.05)。结论:(1)医学研究生的心理健康状况与全国常模相比,其心理健康状况较好;(2)女研究生的心理健康状况略优于男研究生;研一学生的心理健康水平较研二和研三差。     

装甲兵应对方式心理控制源与心理健康关系的研究

目的探讨装甲兵应对方式、心理控制源与心理健康之间的关系.方法采用应对方式问卷、内在-外在心理控制源量表和SCL-90症状自评量表对某部557名装甲兵进行测试及分析.结果 (1)应对方式、心理控制源各因子与SCL-90各因子显著相关(P ＜0.01);(2)采用不成熟应对方式、具有外控倾向的人心理健康水平较低;(3)内控倾向的人多采用成熟的应对方式,具有较高的心理健康水平.结论培养装甲兵成熟的应对方式、内控倾向,对维护和增进装甲兵的心理健康水平有重要意义.     

中专技工学校新生的心理健康与述情障碍的调查分析

目的 了解中专技工学校新生的心理健康水平和述情障碍的相互关系.方法 采用SCL-90量表、多伦多述情障碍量表(TAS)对某中技学校的1 397名入学新生进行问卷调查分析.结果 中技新生SCL-90量表各因子与青年学生的常模比较差异有显著性(P＜0.001).SCL-90评分与TAS总分、TAS1、TAS2呈正相关,与TAS3呈负相关.SCL-90总分受TAS1,TAS2,TAS3的影响(P＜0.001).结论 中专技工学校新生存在一定的心理健康问题,心理健康水平在一定程度上受他们的述情障碍水平影响,有必要对他们进行针对性的心理干预和训练.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.