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1.
Single breath-hold diffusion-weighted imaging of the abdomen 总被引:22,自引:0,他引:22
Chow LC Bammer R Moseley ME Sommer FG 《Journal of magnetic resonance imaging : JMRI》2003,18(3):377-382
PURPOSE: To generate high quality diffusion-weighted images (DWI) and corresponding isotropic ADC maps of the abdomen with full organ (kidneys) coverage in a single breath-hold. MATERIALS AND METHODS: DWI was performed in 12 healthy subjects with an asymmetric, spin-echo, single-shot EPI readout on a system with high performance gradients (40 mT/minute). The isotropic diffusion coefficient was measured from maps and SNR was determined for both diffusion-weighted and reference images in the liver, spleen, pancreas, and kidneys. In six patients, single-axis diffusion encoding along three orthogonal axes (12 NEX) was employed to assess anisotropic diffusion in kidneys. RESULTS: This technique yielded images of quality and resolution which compares favorably to that of prior work. SNR ranged from 27.0 in liver to 44.1 in kidneys for the diffusion-weighted images, and from 19.6 in liver to 39.0 in kidneys in reference images. ADCs obtained in the renal medulla, renal cortex, liver, spleen, and pancreas were (2091 +/- 55) x 10(-6), (2580 +/- 53) x 10(-6), (1697 +/- 52) x 10(-6), (1047 +/- 82) x 10(-6), and (2605 +/- 168) x 10(-6) mm(2)/second, respectively (mean +/- SE). Apparent diffusion coefficient (ADC) in the renal medulla and cortex were significantly different by paired t-test (P = 4.22 x 10(-10)). Renal medulla and cortex yielded anisotropy indices (AI) of 0.129 and 0.067, respectively. CONCLUSIONS: 1) Single-shot SE EPI DWI in the abdomen with this technique provides high quality images and maps with full organ coverage in a single breath-hold; 2) ADCs obtained in the renal medulla and cortex are significantly different; and 3) diffusion within the renal medulla is moderately anisotropic. 相似文献
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Parallel imaging and diffusion tensor imaging for diffusion-weighted MRI of the liver: preliminary experience in healthy volunteers 总被引:14,自引:0,他引:14
Taouli B Martin AJ Qayyum A Merriman RB Vigneron D Yeh BM Coakley FV 《AJR. American journal of roentgenology》2004,183(3):677-680
OBJECTIVE: Our aim was to determine whether parallel imaging and diffusion tensor imaging affect the measurement of apparent diffusion coefficient (ADC) during diffusion-weighted MRI of the liver in healthy volunteers. SUBJECTS AND METHODS: We performed breath-hold single-shot echo-planar diffusion-weighted MRI of the liver in 10 healthy volunteers using conventional diffusion, conventional diffusion with parallel imaging, and diffusion tensor with parallel imaging sequences. TE values for the three sequences were 83, 74, and 63, respectively. Liver signal intensity was measured on all sequences and normalized to the SD of the measurement. Hepatic ADC was calculated by acquiring all sequences with b values of 0 and 500 sec/mm(2). RESULTS: The normalized liver signal intensity was higher on diffusion tensor with parallel imaging and conventional diffusion with parallel imaging than on conventional diffusion without parallel imaging for a b value of 500 sec/mm(2) (13.0 and 10.1 vs 9.1, respectively; p < 0.03) and for a b value of 0 sec/mm(2) (9.0 and 7.6 vs 6.9, respectively; without reaching a significant difference, p = 0.12). Hepatic ADC was not significantly different between sequences (p = 0.16). CONCLUSION: Higher signal intensity can be obtained when using parallel imaging and diffusion tensor imaging during diffusion-weighted MRI of the liver without compromising hepatic ADC measurement. 相似文献
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Functional evaluation of transplanted kidneys with diffusion-weighted and BOLD MR imaging: initial experience 总被引:9,自引:0,他引:9
Thoeny HC Zumstein D Simon-Zoula S Eisenberger U De Keyzer F Hofmann L Vock P Boesch C Frey FJ Vermathen P 《Radiology》2006,241(3):812-821
PURPOSE: To prospectively evaluate feasibility and reproducibility of diffusion-weighted (DW) and blood oxygenation level-dependent (BOLD) magnetic resonance (MR) imaging in patients with renal allografts, as compared with these features in healthy volunteers with native kidneys. MATERIALS AND METHODS: The local ethics committee approved the study protocol; patients provided written informed consent. Fifteen patients with a renal allograft and in stable condition (nine men, six women; age range, 20-67 years) and 15 age- and sex-matched healthy volunteers underwent DW and BOLD MR imaging. Seven patients with renal allografts were examined twice to assess reproducibility of results. DW MR imaging yielded a total apparent diffusion coefficient including diffusion and microperfusion (ADC(tot)), as well as an ADC reflecting predominantly pure diffusion (ADC(D)) and the perfusion fraction. R2* of BOLD MR imaging enabled the estimation of renal oxygenation. Statistical analysis was performed, and analysis of variance was used for repeated measurements. Coefficients of variation between and within subjects were calculated to assess reproducibility. RESULTS: In patients, ADC(tot), ADC(D), and perfusion fraction were similar in the cortex and medulla. In volunteers, values in the medulla were similar to those in the cortex and medulla of patients; however, values in the cortex were higher than those in the medulla (P < .05). Medullary R2* was higher than cortical R2* in patients (12.9 sec(-1) +/- 2.1 [standard deviation] vs 11.0 sec(-1) +/- 0.6, P < .007) and volunteers (15.3 sec(-1) +/- 1.1 vs 11.5 sec(-1) +/- 0.5, P < .0001). However, medullary R2* was lower in patients than in volunteers (P < .004). Increased medullary R2* was paralleled by decreased diffusion in patients with allografts. A low coefficient of variation in the cortex and medulla within subjects was obtained for ADC(tot), ADC(D), and R2* (<5.2%), while coefficient of variation within subjects was higher for perfusion fraction (medulla, 15.1%; cortex, 8.6%). Diffusion and perfusion indexes correlated significantly with serum creatinine concentrations. CONCLUSION: DW and BOLD MR imaging are feasible and reproducible in patients with renal allografts. 相似文献
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Echo-train STIR MRI of the liver: comparison of breath-hold and non-breath-hold imaging strategies 总被引:1,自引:0,他引:1
Earls JP Rofsky NM DeCorato DR Krinsky GA Weinreb JC 《Journal of magnetic resonance imaging : JMRI》1999,9(1):87-92
The purpose of this study was to evaluate echo-train short inversion-time inversion recovery (STIR) sequences and compare the results obtained with breath-hold and non-breath-hold imaging strategies. Forty-one patients referred for hepatic magnetic resonance were imaged with both a breath-hold STIR (BH-STIR; acquisition time [TA] 16-20 seconds x 2) and a non-breath-hold STIR (NBH-STIR; TA 210-256 seconds). Quantitative analysis of the liver, spleen, and up to five hepatic lesions per patient was performed. Three blinded readers recorded the number of focal lesions depicted by each study and qualitatively evaluated overall image quality, lesion conspicuity, and image artifacts. The BH-STIR had greater sensitivity (98.8% vs. 91.6%) for detection of hepatic lesions than the NBH-STIR. The BH-STIR was statistically superior in four measures of image quality and had fewer image artifacts. The NBH-STIR images had statistically higher signal-to-noise (S/N, P < 0.001) and liver-lesion contrast-to-noise (C/N, P = 0.005) ratios. For the evaluation of focal hepatic lesions, a breath-hold echo-train STIR sequence provided superior overall image quality and allowed for detection of more lesions in a shorter amount of time than a non-breath-hold echo-train STIR sequence. 相似文献
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Lung morphology: fast MR imaging assessment with a volumetric interpolated breath-hold technique: initial experience with patients 总被引:6,自引:0,他引:6
PURPOSE: To prospectively evaluate the clinical feasibility of magnetic resonance (MR) imaging of the lungs with fast volumetric interpolated three-dimensional (3D) gradient-recalled-echo (GRE) sequences and to compare this examination with standard computed tomography (CT) in patients with lung abnormalities. MATERIALS AND METHODS: Twenty-five patients with different lung abnormalities were examined with 3D GRE MR imaging. The small pulmonary nodules in seven, TNM stage of large intrapulmonary tumors in eight, and benign bronchial disease in five patients were evaluated. MR imaging-based diagnoses were compared with diagnoses made at CT and at discharge from the hospital. Contingency tables and the McNemar test were used to evaluate the significance of differences between MR imaging- and CT-based diagnoses. RESULTS: The MR imaging- and CT-based diagnoses were identical in 24 of 25 patients. In the remaining patient, clinical findings confirmed the accuracy of the MR imaging finding of pleural empyema. Ten of 15 solid pulmonary nodules smaller than 10 mm in diameter were detected at MR imaging (P >.1). Tumor stages at MR imaging and CT were identical, but lymph node stages at the two examinations differed in two of eight patients owing to overestimation of lymph node size at MR imaging (P >.2). In the five patients with bronchiectasis, MR imaging depicted 26 of 33 affected lung segments; differences between MR imaging and CT findings of bronchial dilatation (P >.05) and bronchial wall thickening (P >.2) were not significant. Peribronchial fibrosis was overestimated at MR imaging owing to image artifacts (P <.05). CONCLUSION: Study results confirmed the feasibility of fast breath-hold 3D GRE MR imaging of the lung. 相似文献
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F H Doyle J M Pennock L M Banks M J McDonnell G M Bydder R E Steiner I R Young G J Clarke T Pasmore D J Gilderdale 《AJR. American journal of roentgenology》1982,138(2):193-200
Nuclear magnetic resonance (NMR) scans of the liver were obtained in 12 normal volunteers and 32 patients using a whole-body machine developed by Thorn-EMI Ltd., and the results were compared with x-ray computed tomography (CT). Two types of NMR scan, saturation-recovery and inversion-recovery, were performed in order to obtain values for the spin-lattice relaxation time, T1. Although the saturation-recovery scans show little soft-tissue detail, the inversion-recovery scans demonstrated the interlobar fissure, hepatic veins, portal veins, bile ducts, and gallbladder. In comparison with CT (Siemens Somatom 2), both types of NMR scan showed some blurring due to respiratory movement but much less linear artifact across the liver from the air-fluid interface in the stomach. Focal disease within the liver was demonstrated by both CT and NMR, although an area of focal atrophy and another of hepatic infarction were only recognized with NMR. In diffuse disease the pattern varied. In steatosis CT was virtually diagnostic, while NMR showed no specific features. In hemochromatosis, hepatitis, eight cases of cirrhosis, and one of Wilson disease, both techniques showed abnormalities of varying specificity. In two cases of cirrhosis and one of primary biliary cirrhosis, only the NMR scan was abnormal. Nuclear magnetic resonance images are now sufficiently anatomically detailed to permit serious comparisons with technically advanced computed tomography. The information revealed is fundamentally different and can be expected to have some diagnostic utility. 相似文献
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Oner AY Celik H Tali T Akpek S Tokgoz N 《Acta radiologica (Stockholm, Sweden : 1987)》2007,48(4):456-463
BACKGROUND: Thin-section diffusion-weighted imaging (DWI) is known to improve lesion detectability, with long imaging time as a drawback. Parallel imaging (PI) is a technique that takes advantage of spatial sensitivity information inherent in an array of multiple-receiver surface coils to partially replace time-consuming spatial encoding and reduce imaging time. PURPOSE: To prospectively evaluate a 3-mm-thin-section DWI technique combined with PI by means of qualitative and quantitative measurements. MATERIAL AND METHODS: 30 patients underwent conventional echo-planar (EPI) DWI (5-mm section thickness, 1-mm intersection gap) without parallel imaging, and thin-section EPI-DWI with PI (3-mm section thickness, 0-mm intersection gap) for a b value of 1000 s/mm(2), with an imaging time of 40 and 80 s, respectively. Signal-to-noise ratio (SNR), relative signal intensity (rSI), and apparent diffusion coefficient (ADC) values were measured over a lesion-free cerebral region on both series by two radiologists. A quality score was assigned for each set of images to assess the image quality. When a brain lesion was present, contrast-to-noise ratio (CNR) and corresponding ADC were also measured. Student t-tests were used for statistical analysis. RESULTS: Mean SNR values of the normal brain were 33.61+/-4.35 and 32.98+/-7.19 for conventional and thin-slice DWI (P>0.05), respectively. Relative signal intensities were significantly higher on thin-section DWI (P<0.05). Mean ADCs of the brain obtained by both techniques were comparable (P>0.05). Quality scores and overall lesion CNR were found to be higher in thin-section DWI with parallel imaging. CONCLUSION: A thin-section technique combined with PI improves rSI, CNR, and image quality without compromising SNR and ADC measurements in an acceptable imaging time. 相似文献
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High-spatial-resolution multistation MR angiography with parallel imaging and blood pool contrast agent: initial experience 总被引:3,自引:0,他引:3
Nikolaou K Kramer H Grosse C Clevert D Dietrich O Hartmann M Chamberlin P Assmann S Reiser MF Schoenberg SO 《Radiology》2006,241(3):861-872
The purpose of this study was to prospectively evaluate the diagnostic accuracy of reader detection of 75% or greater stenosis at high-spatial-resolution multistation magnetic resonance (MR) angiography performed with matrix coils and a blood pool contrast agent. Ten healthy volunteers and 10 patients were examined. All participants provided informed consent to participate in this institutional review board-approved study. For contrast agent-enhanced multistation MR angiography, an albumin-binding gadolinium chelate, gadofosveset trisodium, was used. Imaging was performed during the first-pass and steady-state phases of the contrast agent. Vessel conspicuity on the first-pass MR angiograms obtained in both volunteers and patients was rated as excellent for 93% of vessels. At steady-state imaging, vessel conspicuity was rated as excellent or good for 89% of vessels. Gadofosveset trisodium-enhanced MR angiography yielded sensitivities of 100% and 97% and specificities of 96% and 97% for detection of significant disease in the carotid and lower extremity arteries, respectively. 相似文献
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Diagnosis of liver metastases: value of diffusion-weighted MRI compared with gadolinium-enhanced MRI
Andrew D. Hardie Mohit Naik Elizabeth M. Hecht Hersh Chandarana Lorenzo Mannelli James S. Babb Bachir Taouli 《European radiology》2010,20(6):1431-1441
Objective
The full diagnostic value of diffusion-weighted (DW) MRI in the evaluation of liver metastases remains uncertain. The aim of the present study was to assess the diagnostic accuracy of DW-MRI and contrast-enhanced MRI (CE-MRI) using extracellular gadolinium chelates, with the reference standard established by consensus interpretation of confirmatory imaging and histopathologic data. 相似文献15.
We sought to compare a three-dimensional, contrast-enhanced, magnetic resonance angiogram (3D CE MRA) sequence combining parallel-imaging
(generalised autocalibrating partially parallel acquisitions (GRAPPA)) with a time-resolved echo-shared angiographic technique
(TREAT) in an intraindividual comparison to a standard 3D MRA sequence. Four healthy volunteers (27–32 years), and 11 patients
(11–82 years) with vascular pathologies of the hand were examined on a 1.5-Tesla (T) MR system (Magnetom Avanto, Siemens,
Erlangen, Germany) using two multichannel receiver coils. Following automatic injection (flow rate 2.5 cc/s) of 0.1 mmol/kg
gadoterate (Dotarem, Guerbet, Roissy, France), 32 consecutive 3D data sets were collected with the TREAT sequence (TR/TE:
4.02/1.31 ms, FA: 10°, GRAPPA acceleration factor: R=2, TREAT factor: 5, voxel size: 1.0×0.7×1.3 mm3) and a T1-wwighted 3D gradient-echo sequence (TR/TE: 5.3/1.57 ms, FA: 30°, GRAPPA acceleration factor: 2, voxel size: 0.71×0.71×0.71 mm3,). MR data sets were evaluated and compared for image quality and visualisation of vascular details. In the volunteer group,
all MR imaging was successful while technical problems prevented acquisition of the standard protocol in two patients. For
the corresponding segments, the number of visible segments was equal on both sequences. Overall image quality was significantly
better on the standard protocol than on the TREAT protocol. TREAT MRA provided functional information in lesions with rapid
blood flow, e.g. detection of feeding and draining vessels in an haemangioma. TREAT-MRA is a robust technique that combines
morphological and functional information of the hand vasculature and deals with the very special physiological demands of
vascular lesions, such as quick arteriovenous transit time. 相似文献
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Vandecaveye V de Keyzer F Vander Poorten V Deraedt K Alaerts H Landuyt W Nuyts S Hermans R 《The British journal of radiology》2006,79(944):681-687
Radiotherapy-induced changes in the soft tissues of the neck hamper the early detection of persistent or recurrent tumour by clinical examination and imaging procedures. Diffusion-weighted (DW) MRI is a non-invasive technique capable of probing tissue properties by measuring the movement of water. The purpose of the ongoing study is to examine the usefulness of DW-MRI for differentiation of persistent or recurrent tumour from post-radiotherapeutic sequelae or complications. Four patients, suspected of tumour recurrence after radiotherapy for laryngeal squamous cell carcinoma, were examined using a DW-MRI sequence on a clinical 1.5 T MR system prior to surgery. In two patients, the DW-MRI images showed an asymmetric hyperintense lesion on b1000 images with low apparent diffusion coefficient (ADC)-value, compatible with tumour on histopathology. All surrounding tissue presented high ADC values and absent signal on the b1000 images, histopathologically correlating to post-radiotherapeutic changes. The images of the third and fourth patient showed absent or minimal symmetric hyperintensity of the laryngeal soft tissues on the b1000 images and high ADC-values. In these cases, the histopathological diagnosis of radionecrosis was made and no tumour was found. In all four cases, differentiation of tumoral tissue from radiotherapy-induced tissue alterations was possible with DW-MRI. 相似文献
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Single breath-hold T2-weighted MR imaging of the liver: value of single-shot fast spin-echo and multishot spin-echo echoplanar imaging 总被引:4,自引:0,他引:4
Hori M Murakami T Kim T Kanematsu M Tsuda K Takahashi S Takamura M Hoshi H Nakamura H 《AJR. American journal of roentgenology》2000,174(5):1423-1431
OBJECTIVE: The objective of our study was to evaluate the efficacy of single breath-hold T2-weighted MR imaging for detection of focal hepatic lesions. MATERIALS AND METHODS: T2-weighted MR images were retrospectively reviewed from 51 patients with 85 solid and 59 nonsolid lesions using the following four sequences: conventional spin-echo, respiratory-triggered fast spin-echo, single-shot fast spin-echo, and multishot spin-echo echoplanar imaging. Images were reviewed on a hepatic segment-by-segment basis; T2-weighted images of a total of 408 hepatic segments were reviewed separately and independently for solid and nonsolid lesions by four radiologists. Quantitative, qualitative, and receiver operating characteristic analyses were performed. RESULTS: For solid lesions, no significant differences were seen among the lesion-to-liver contrast-to-noise ratios with the four sequences. In terms of solid lesion detection, no significant difference was seen between the diagnostic accuracy of multishot spin-echo echoplanar (Az = 0.90) and respiratory-triggered fast spin-echo (Az = 0.91) imaging, which showed the best performance of the four sequences. For nonsolid lesion detection, respiratory-triggered fast spin-echo and single-shot fast spin-echo imaging were judged the best (Az = 0.94). CONCLUSION: Breath-hold single-shot fast spin-echo and multishot spin-echo echoplanar sequences can be substituted for conventional spin-echo and respiratory-triggered fast spin-echo T2-weighted sequences. 相似文献
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Koh DM Collins DJ Wallace T Chau I Riddell AM 《The British journal of radiology》2012,85(1015):980-989
Objectives
To compare the diagnostic accuracy of gadolinium-ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced MRI, diffusion-weighted MRI (DW-MRI) and a combination of both techniques for the detection of colorectal hepatic metastases.Methods
72 patients with suspected colorectal liver metastases underwent Gd-EOB-DTPA MRI and DW-MRI. Images were retrospectively reviewed with unenhanced T1 and T2 weighted images as Gd-EOB-DTPA image set, DW-MRI image set and combined image set by two independent radiologists. Each lesion detected was scored for size, location and likelihood of metastasis, and compared with surgery and follow-up imaging. Diagnostic accuracy was compared using receiver operating characteristics and interobserver agreement by kappa statistics.Results
417 lesions (310 metastases, 107 benign) were found in 72 patients. For both readers, diagnostic accuracy using the combined image set was higher [area under the curve (Az) = 0.96, 0.97] than Gd-EOB-DTPA image set (Az = 0.86, 0.89) or DW-MRI image set (Az = 0.93, 0.92). Using combined image set improved identification of liver metastases compared with Gd-EOB-DTPA image set (p<0.001) or DW-MRI image set (p<0.001). There was very good interobserver agreement for lesion classification (κ = 0.81–0.88).Conclusions
Combining DW-MRI with Gd-EOB-DTPA-enhanced T1 weighted MRI significantly improved the detection of colorectal liver metastases.In patients with colorectal cancer, accurate assessment of the size, location and segmental distribution of liver metastases on a per-lesion basis is critical for treatment planning [1]. Accurate depiction of the size and distribution of liver metastases helps the selection of patients to undergo radical surgery [2,3] or minimally invasive therapy, such as radiofrequency ablation (RFA) [4], chemo-embolisation or radio-embolisation [5].The image contrast in diffusion-weighted MRI (DW-MRI) is based on differences in the mobility of water between tissues [6]. In tumour tissues, such as liver metastases, water mobility is often more impeded compared with normal parenchyma. Hence, metastases appear to have high signal intensity on DW-MRI, facilitating their detection.Compared with conventional T2 weighted imaging, DW-MRI has been found to be superior for lesion detection in the liver [7-9]. When compared with contrast-enhanced MRI, DW-MRI had a higher diagnostic accuracy compared with superparamagnetic iron oxide (SPIO)-enhanced MRI [10] and similar diagnostic accuracy compared with gadolinium contrast-enhanced imaging [11] for detecting colorectal liver metastases. DW-MRI has also been found to be more sensitive than fluorodeoxyglucose (18FDG) positron emission tomography (PET) CT [12] for the same clinical indication. In another study, combining DW-MRI with T1 weighted imaging after liver-specific contrast medium mangafodipir trisodium (MnDPDP) administration improved the diagnostic accuracy of colorectal liver metastases detection compared with either technique alone [13].Gadolinium-ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA; Eovist or Primovist; Bayer Schering Pharma, Berlin, Germany) is a relatively new hepatocyte-selective MR contrast medium that has been shown to be useful detecting liver metastases measuring <1 cm in diameter [14,15]. Delayed T1 weighted imaging in the hepatocellular phase of contrast enhancement at 20 min to several hours after contrast administration demonstrates metastases as T1 hypointense lesions against the avidly enhancing liver parenchyma.Both DW-MRI and Gd-EOB-DTPA-enhanced MRI are useful for the detection of liver metastases [7,8,14-16]. One study performed at 3 T compared the diagnostic performance of the two techniques for the identification of small (<2 cm) liver metastases [17]. Another study at 1.5 T independently compared the diagnostic performance of DW-MRI, dynamic phase MRI and hepatobiliary phase Gd-EOB-DTPA-enhanced MRI [18]. However, the possible incremental value of combining DW-MRI with Gd-EOB-DTPA-enhanced MRI for detecting colorectal metastases has not been reported. Hence, the aim of this study was to compare the diagnostic accuracy of Gd-EOB-DTPA-enhanced MRI, DW-MRI and a combination of both techniques for the detection of colorectal hepatic metastases. 相似文献19.
Yamada K Sakai K Hoogenraad FG Holthuizen R Akazawa K Ito H Oouchi H Matsushima S Kubota T Sasajima H Mineura K Nishimura T 《AJNR. American journal of neuroradiology》2007,28(9):1668-1673
BACKGROUND AND PURPOSE: The purpose of this work was to test the feasibility of using high angular resolution diffusion imaging (HARDI)-based multitensor tractography to depict motor pathways in patients with brain tumors. MATERIALS AND METHODS: Ten patients (6 males and 4 females) with a mean age of 52 years (range, 9-77 years) were scanned using a 1.5T clinical MR unit. Single-shot echo-planar imaging was used for diffusion-weighted imaging (repetition time, 6000 ms; excitation time, 88 ms) with a diffusion-sensitizing gradient in 32 orientations and a b-value of 1000 s/mm(2). Data postprocessing was performed using both the conventional single- and multitensor methods. The depiction rate of the 5 major components of the motor pathways, that is, the lower extremity, trunk, hand, face, and tongue, was assessed. RESULTS: Motor fibers on both lesional and contralesional sides were successfully depicted by both the single-tensor and multitensor techniques. However, with the single-tensor model, the depiction of motor pathways was typically limited to the fibers of trunk areas. With the multitensor technique, at least 4 of 5 major fiber bundles arising from the primary motor cortex could be identified. CONCLUSION: HARDI-based multitensor tractography using a standard b-value (1000 s/mm(2)) can depict the fiber tracts from the face and tongue regions of the primary motor cortex. 相似文献
20.
Zech CJ Herrmann KA Dietrich O Horger W Reiser MF Schoenberg SO 《Investigative radiology》2008,43(4):261-266
OBJECTIVES: To evaluate the performance of black-blood diffusion-weighted (DW)-EPI sequences with parallel imaging for the detection of focal liver lesions in comparison with a standard T2-weighted (T2-w) sequence. MATERIALS AND METHODS: Twenty patients with known or suspected focal liver lesions underwent liver MRI using a DW-EPI sequence with a b-value of 50 S/mm2 (TR/TE 2200/50 ms) and a standard fat-saturated T2-w sequence (TR/TE 2800/107 ms) with 6-mm slice thickness on a 1.5-T MRI system. Both sequences used parallel imaging with an acceleration factor of 2. Overall image quality and degree of artifacts were compared on a 5-point scale with 5 being the most desirable score. The detection rate and the level of confidence with regard to lesion detection were evaluated for both sequences in comparison to a contrast-enhanced (Gadolinium and SPIO) MR examination, which was used as the standard of reference. RESULTS: The DW-EPI sequence showed significantly (P < 0.05) improved overall image quality (average score 4.15 vs. 3.63) and fewer artifacts (average score 4.2 vs. 3.5) in comparison with the T2-w sequence. The sensitivity for lesion detection was superior in the DW-EPI sequence (83% vs. 61%). The level of confidence in the detection of focal liver lesions was also superior for the DW-EPI sequence in comparison with the T2-w sequence (average score 3.9 vs. 3.2). CONCLUSIONS: DW-EPI sequences for liver-imaging are feasible with parallel imaging and show excellent image quality. They may contribute to more easy and confident lesion detection in comparison with T2-w sequences. 相似文献