共查询到20条相似文献,搜索用时 140 毫秒
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目的:建立同时测定苦木注射液中3种活性成分3-甲基-铁屎米-2,6-二酮、4-甲氧基-5-羟基铁屎米酮、4,5-二甲氧基-铁屎米酮含量的分析方法。方法:采用高效液相色谱法,色谱柱为Phenom enex Gem in i C18(150 mm×4.6 mm,5μm)柱,流动相为pH 7.5的0.2 mol.L-1磷酸氢二钠及磷酸二氢钠缓冲液(A)?甲醇(B),梯度洗脱,流速1 mL.m in-1,检测波长254 nm,柱温30℃。结果:苦木注射液中3-甲基-铁屎米-2,6-二酮、4-甲氧基-5-羟基铁屎米酮、4,5-二甲氧基-铁屎米酮线性范围分别为0.0380~0.7600μg(r=0.9999),0.0450~0.9000μg(r=0.9999),0.0287~0.574μg(r=0.9999);平均加样回收率(n=9)分别为99.3%,101.4%,101.8%。结论:该方法操作简单,重复性好,为评价和监控苦木注射液的质量提供可靠的方法。 相似文献
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蒿属中药南刘寄奴脂溶性成分的分离鉴定 总被引:5,自引:0,他引:5
从南刘寄奴Artemisia anomala S.Moore中分得两个香豆素,两个黄酮,一个三萜醇,一个二肽类化合物和一个倍半萜内酯。其中,奇蒿黄酮(arteanoflavone)首次从天然物中分离,奇蒿内酯(arteanomalactone)为一新倍半萜内酯。 相似文献
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目的研究长尾粗叶木根乙酸乙酯部分中抗类风湿性关节炎的有效成分。方法采用各种色谱方法分离纯化,运用现代波谱技术(1D,2D-NMR和HRMS等)鉴定各种化学成分,并对所分得的化学成分进行抑制β-葡萄糖酸苷酶释放的抗炎活性的筛选。结果从长尾粗叶木乙酸乙酯部分分得8个化合物,分别是:长尾粗叶木内酯A(1)、党参内酯(2)、2,5-二甲氧基-1,4-苯醌(3)、钩藤苷元A(4)、正十九醇(5)、顺-二十二碳-13-烯酸(6)、二十四烷酸(7)和β-谷甾醇(8)。另外,化合物3对PAF刺激的小鼠多形核白细胞β葡糖苷酸酶的释放具有明显的抑制作用。结论化合物1是自然界首次发现的新化合物,其他化合物均是首次从该属植物中分得,化合物3是长尾粗叶木根的抗炎有效成分。 相似文献
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穿心莲中两种新的二萜内酯甙的分离和结构测定 总被引:1,自引:0,他引:1
本文报道了自穿心莲(Andrographis paniculata Nees)醇提取物中分得两种新的二萜内酯甙:14-去氧穿心莲内酯甙(14-deoxyandrographoside)[Ⅴ]及穿心莲内酯甙(andrographoside)[Ⅶ]。经紫外光谱、红外光谱、质谱及核磁共振氢谱分析,水解及衍生物的制备证明[Ⅴ]为14-去氧穿心莲内酯-19-β-葡萄糖甙,[Ⅶ]为穿心莲内酯-19-β-葡萄糖甙。 相似文献
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在继续寻找具有生物活性的内酯时,作者研究了金光菊属植物R.mollis Ell.的化学成分。从其地上部分分得新的倍半萜内酯rudmollin(2a)、4-乙酰氧基rudmolfin(2b)、15-乙酰氧基rudmollin(2c)和rudmollitrin(4b)。 相似文献
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Seven compounds were isolated from the stem of Acanthopanax senticosus by repeated column chromatography. Their structures were elucidated as isovanillin (1), (-)-sesamin (2), isofraxidin (3), (+)-syringaresinol (4), 5-hydroxymethylfurfural (5), eleutheroside B (6), and eleutheroside E (7) by spectral analysis. Among them, isovanillin (1) was isolated for the first time from the family Araliaceae. 相似文献
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Jacaranone and related compounds (1-3) were isolated, along with three triterpenes (4-6), from the fresh fruits of Ternstroemia japonica. The compounds were identified as jacaranone (1), 3-hydroxy-2,3-dihydrojacaranone (2), 3-methoxy-2,3-dihydrojacaranone (3), 3-O-acetyloleanolic acid (4), 3-O-acetylursolic acid (5), and ursolic acid (6). Jacaranone and its derivatives were isolated for the first time from Theaceae. Of the isolated compounds, compound 3 is a new compound. Jacaranone (1) exhibited weak antioxidative effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. 相似文献
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喙果黑面神化学成分研究 总被引:2,自引:0,他引:2
目的研究大戟科植物喙果黑面神(Breynia rostrata Merr.)的化学成分。方法利用硅胶、凝胶等色谱技术分离纯化化学成分,根据化合物的理化性质和光谱数据进行结构鉴定。结果从喙果黑面神的正丁醇萃取部分分离得到4个化合物,分别鉴定为6-O-甲基丙酰基-α-D-吡喃葡糖(6-O-methylpropanoyl-α-D-glucopyranose,1);4″-苯酚基-6-O-甲基丙酰基-β-D-吡喃葡糖苷(4″-phenolic-6-O-methylpropanoyl-β-D-glucopyranoside,2);1-O-没食子酰基-β-D-吡喃葡糖苷(1-O-galloyl-β-D-glucopyranoside,3);熊果苷(arbutin,4)。结论化合物1和2为新化合物,3和4均为首次从该种植物分离得到。 相似文献
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刺异叶花椒化学成分研究 总被引:5,自引:0,他引:5
目的 研究刺异叶花椒(Zanthoxylum dimorphophyllum Hemsl. var spinifolum Rhed . et Wils)的化学成分。方法 采用现代色谱技术进行化学成分的分离,运用光谱方法确定所分离化合物的结构。结果 分离得到5个化合物,分别鉴定为6-(3′-甲基2′,3′-丁二醇基)-7-乙酰氧基香豆素(I) ,6-(3′-甲基-2′,3′-丁二醇基) 香豆素-7-O-β-D-吡喃葡糖苷(II) ,正二十六烷酸(III) ,葡萄内酯(IV) ,5 ,3′-二羟基-4-甲氧基-二氢黄酮-7-[O-β-D-吡喃葡萄糖(6→1)-α-L-鼠李糖]苷(V)。结论 化合物I -V均为首次从该植物中分得,其中I为新化合物 相似文献
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中药白头翁地上部分的三萜皂苷成分 总被引:1,自引:0,他引:1
为了研究白头翁地上部分的三萜皂苷成分,采用不同色谱技术对白头翁地上部分乙醇提取物的正丁醇部位进行分离纯化,并用波谱和化学方法鉴定化合物的结构。从正丁醇部位中共分离得到7个三萜皂苷类化合物,其结构分别被鉴定为2β-羟基常春藤皂苷元28-O-α-L-吡喃鼠李糖(1→4)-β-D-吡喃葡糖(1→6)-β-D-吡喃葡糖酯苷(1)、3-O-α-L-吡喃阿拉伯糖常春藤皂苷元28-O-α-L-吡喃鼠李糖(1→4)-β-D-吡喃葡糖(1→6)-β-D-吡喃葡糖酯苷(2)、3-O-α-L-吡喃鼠李糖(1→2)-α-L-吡喃阿拉伯糖齐墩果酸28-O-α-L-吡喃鼠李糖(1→4)-β-D-吡喃葡糖(1→6)-β-D-吡喃葡糖酯苷(3)、3-O-α-L-吡喃鼠李糖(1→2)[β-D-吡喃葡糖(1→4)]-α-L-吡喃阿拉伯糖常春藤皂苷元28-O-α-L-吡喃鼠李糖(1→4)-β-D-吡喃葡糖(1→6)-β-D-吡喃葡糖酯苷(4)、3-O-α-L-吡喃鼠李糖(1→2)-α-L-吡喃阿拉伯糖常春藤皂苷元28-O-α-L-吡喃鼠李糖(1→4)-β-D-吡喃葡糖(1→6)-β-D-吡喃葡糖酯苷(5)、常春藤皂苷元28-O-α-L-吡喃鼠李糖(1→4)-β-D-吡喃葡糖(1→6)-β-D-吡喃葡糖酯苷(6)及常春藤皂苷元3-O-α-L-吡喃鼠李糖(1→2)-α-L喃阿拉伯糖苷(7)。其中化合物1为新化合物,化合物2~6为首次从该植物中分离得到。 相似文献
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A new pterocarpan, (-)-maackiain sulfate,from the roots of<Emphasis Type="Italic">Sophora subprostrata</Emphasis> 总被引:2,自引:0,他引:2
A new pterocarpan, (-)-maackiain 3-sulfate (1) was isolated from the methanol extract of roots of Sophora subprostarata together with (-)-maackiain (2), trifolirhizin (3), lupeol (4), ononin (5), 7,4'-dihydroxyflavone (6), and (+)-syringaresinol (7). The structure of 1 was determined by analyses of 2D NMR and HRFABMS. Compounds 5-7 were isolated from this plant for the first time. 相似文献
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Flavonoids from<Emphasis Type="Italic">Iris spuria</Emphasis> (Zeal) cultivated in Egypt 总被引:1,自引:0,他引:1
Singab AN 《Archives of pharmacal research》2004,27(10):1023-1028
A new 12a-dehydrorotenoid 1, 11-dihydroxy-9, 10-methylenedioxy-12a-dehydrorotenoid (1), together with a new isoflavonoid glycoside tectorigenin-7-O-beta-glucosyl-4'-O-beta-glucoside (3), were isolated and identified from the rhizomes of I. spuria (Zeal). In addition, 4 known compounds, tectorigenin (2) tectorigenin-7-O-beta-glucosyl (1 --> 6) glucoside (4), tectoridin (a tectorigenin-7-O-beta-glucoside) (5) and tectorigenin-4'-O-beta-glucoside (6) were isolated and identified for the first time from this plant. The structures of the isolated compounds were determined by spectroscopic methods (UV, IR, 1H, 13C-NMR, DEPT, HMQC, NOESY, and HMBC experiments and MS spectrometry) and by comparison with literature data of known compounds. Compounds 2, 4, 5, and 6 are reported for the first time from this plant through the present study. 相似文献
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鸦胆子根化学成分的研究 总被引:1,自引:0,他引:1
从鸦胆子〔Brucea javanica(L.)Merr.〕根的乙醇提取物中分离得到十二个单体。经理化常数及光谱分析,鉴定了其中的六个化合物:鸦胆苦醇(Brusatol)、没食子酸乙酯(Ethylgallate)、大黄素(Emodin)、大黄酚(Chrysophanol)、大黄酚葡萄糖甙(Chrysophanein)和β-谷甾醇(β-sitosterol)。该六个化合物均系首次从鸦胆子根中得到。 相似文献
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Five coumarins, isoimperatorin (1), pabulenol (2), isooxypeucedanin (3), oxypeucedanin hydrate (4) and osthol (5) were isolated from the MeOH extract of Angelica genuflexa in the course of searching for anti-platelet and anti-coagulant components from plants. Pabulenol (2) was isolated from A. genuflexa for the first time. The five compounds isolated from A. genuflexa, together with decursinol angelate (6), decursin (7) and nodakenin (8) from A. gigas were evaluated for their effects on platelet aggregation and blood coagulation. Compounds 2, 5, 6 and 7 were observed to be either equally effective or 2-4 times more inhibitory than ASA in both arachidonic acid and U46619 (TXA2 mimetic) induced platelet aggregations. 相似文献