Cohort Study on the Effect of a Combined Treatment of Traditional Chinese Medicine and Western Medicine on the Relapse and Metastasis of 222 Patients with Stage Ⅱ and Ⅲ Colorectal Cancer after Radical Operation

Objective:To evaluate the effectiveness of a comprehensive therapy of traditional Chinese medicine(TCM)in reducing the relapse and metastasis of stageⅡandⅢcolorectal cancer based on conventional Western medicine(WM)therapy.Methods:Two hundred and twenty-two patients in total, diagnosed as stageⅡandⅢcolorectal cancer from February 2000 to March 2006,were recruited from Xiyuan Hospital,China Academy of Chinese Medical Sciences and the General Hospital of Beijing Military Area.They were followed-up once every 3-6 months.Twenty cases dropped out from the cohort.The remaining 202 patients were all treated with routine WM treatment [including R0 radical operation,or chemotherapy or/and radiotherapy according to national comprehensive cancer network(NCCN)clinical guidelines].These patients were assigned to two groups based on whether or not they were additionally treated with TCM comprehensive therapy(orally administered with a decoction according to syndrome differentiation,combined with a traditional patent drug over one year).Ninety-eight patients from Xiyuan Hospital were treated with WM and TCM(combined group),and 104 patients from the General Hospital of Beijing Military Area were treated with WM alone(WM group).The demographic data at baseline were comparable,including the operation times,age,sex,TNM staging,and pathological types.The patients were followed-up for one to five years.Up to now,there are 98,98,77,64,and 47 patients with 1,2,3, 4,and 5 years of follow-up in the combined group,respectively;and 104,104,97,81,and 55 patients in the WM group,respectively.The results of the 5-year follow-up of all the patients will be available in 2011. Results:The relapse/metastasis rate of 1-,2-,3-,4-,and 5-year were 0(0/98),2.04%(2/98),11.69% (9/77),14.06%(9/64),and 21.28%,(10/47)in the combined group,and were 4.80%(5/104),16.35% (17/104),21.65%(21/97),25.93%(21/81),and 38.18%(21/55)in the WM group,respectively.A significant difference was found in the second year between the two groups(χ~2=12.117,P = 0.000).Median relapse/ metastasis time was 26.5 months in the combined group and 16.0 months in the WM group.Conclusion: The combined therapy of TCM and WM may have great clinical value and a potential for decreasing the relapse or metastasis rate in stageⅡandⅢcolorectal cancer after conventional WM therapy.     

Strategies and Methods for the Treatment of Diabetic Neuropathy Using Integrative Chinese and Western Medicine

Diabetic neuropathy （DN） is the most common metabolic neuropathy in clinics, not only in diabetes patients （〉60%）, but also in pre-diabetic （8%） and normal persons （5%）^（1）. Its pathogenesis has not been fully understood up to now. It is generally believed that it is related to the increase in glycation endoproducts （AGEs） caused by hyperglycemia,     

Prospective Study on lntelligence Quotient of Hepatic Lenticular Degneration Patients Treated with Combined Traditional Chinese and Western Medicine

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Discussion about the Prognoses of Wilson＇s Disease with Severe Cortex Structure Impairment--A Case Report of Wilson＇s Disease （WD） Treated by the Traditional Chinese Medicine and Western Medicine

Introduction： As we know, Wilson＇s disease（WD） patient with severe structure and function impairment will have a poor prognosis. We met an exceptional case and madea report, then discussed some viewpoints about prognosis of WD patients. Case report： A WD patient presenting with severe cortex structure and cerebral function impairment was followed up for 5 years, including his therapeutic regiment-the combined treatment of traditional Chinese medicine and western medicine, clinical manifestation, the 24-hr urine copper output and brain MRI. By effective copper-excluding therapy, his clinical manifestation went on worse I st year after diagnosis, and then was improved in the following years. The patient＇s symptoms almost complete recover 3 years afterward. During 5 years, the 24-hr urine copper excreted is tapered, but it was still higher than normal. The cerebral MR image of the patient was getting worse at 1^st year, then began to recover, and improved markedly 5 years after. Conclusion： For WD patients, treated with the traditional Chinese medicine and western medicine, even therapy start in serious conditions and in late adolescent, clinical manifestation may get striking improvement.     

General survey of traditional Chinese medicine and Western medicine researches on tumor metastasis

Aggression and metastasis of tumor cells is themost essential characteristic of malignant tumor's bi-ological behavior , which is the result of a series ofcomplicated and multi-stepped mutual actions be-tween tumor cells and host(1).Clinically , metastasisand recurrence are one of the causes of death oftumor patient . Therefore, pathogenetic mechanismof tumor metastasis andits prevention andtreat mentis the key point of traditional Chinese medicine(TCM) and Western medicine ( WM) in studying…     

晚期大肠癌治疗过程中相关性便秘的中医药治疗

目前大肠癌的治疗仍以手术为主,辅以放化疗、靶向治疗、中医药治疗等综合疗法.在晚期大肠癌的治疗中主要是全身化疗及改善生活质量.在化疗药物、化疗引起的相关性呕吐中所使用的止吐药物及缓解患者疼痛药物的使用中,所引起的不良反应:便秘,已经成为临床治疗中不可忽略的问题.在使用调节肠道功能西医西药治疗疗效相对局限的情形下,中医中药的治疗已经开始逐渐融合入肿瘤病人化疗治疗的过程中.中医的辨证分型论治,依据临床具体情况,结合患者个体差异,准确施治,同时配合针灸的穴位针刺等均效果显著.     

中西医结合治疗方法在胃癌术后早期康复的作用

目的 结合临床实践和传统中医理论,探讨中西医结合治疗方法对胃癌术后早期康复的影响。方法 采用回顾性研究,选取2013年8月至2018年7月于阳江江华医院接受胃癌根治术并接受中西医康复治疗的69例患者作为观察组。按年龄和性别匹配选取胃癌根治术并术后接受常规恢复治疗的69患者作为对照组。比较分析两组患者反映术后早期康复情况的指标。结果 观察组在术后肠鸣音恢复时间、首次肛门排气时间、进流质时间和住院天数上均短于仅对照组(P＜0.05),并发症发生率两组之间差异没有统计学意义(P＞0.05)。结论 对胃癌手术患者术后早期施予中西医结合治疗是行之有效的,具有促进术后胃肠动力和胃肠道消化功能恢复、临床痊愈效率的作用。     

中西医结合治疗肾病综合征的临床研究

将154肾病综合征患者分为实验组和对照组.实验组78例采用中西医结合治疗,实验组76例采用单纯西药(激素、环磷酸胺)进行治疗.结果实验组完全缓解和总有效率分别为55.0%和85.0%,对照组完全缓解和总有效率分别为37%和59.0%,提示中西医结合治疗肾病综合征的疗效明显优于单纯西药治疗.     

中西医结合治疗宫颈癌的临床疗效分析

目的探讨中西医结合治疗宫颈癌的临床疗效。方法选择2009年1月至2010年12月收治于我院的84例宫颈癌患者,按照入院顺序随机分为观察组和对照组,每组42例,对照组患者采用常规西医治疗,观察组患者采用中西医结合治疗,比较两组的临床疗效。结果观察组患者的治疗总有效率为95.2%,对照组为73.8%,前者显著优于后者,差异有统计学意义(P<0.05)。结论中西医结合治疗宫颈癌疗效显著且无严重的毒副作用,值得临床推广应用。     

中西医结合治疗老年痴呆效果分析

目的：探讨中西医结合治疗老年痴呆的临床疗效。方法：将我院2009年1月~2010年1月收治的63例老年痴呆患者随机分为观察组（42例）和对照组（21例）,对照组给予西药都可喜治疗,观察组在此基础上加用自制中药辨证施治。观察两组患者治疗前后MMSE、ADL、HDS评分及总有效率,并进行对比分析。结果：两组患者治疗后MMSE、HDS评分均较治疗前有明显提高,ADL评分较治疗前有明显下降,治疗前后评分比较差异有统计学意义（P〈0.05）。观察组治疗后MMSE、HDS评分为（24.12±4.25）分、（26.44±5.25）分,明显高于对照组的（20.09±2.25）分、（25.35±4.46）分,ADL评分为（27.05±7.99）分,明显低于对照组的（32.33±8.67）分,组间比较差异有统计学意义（P〈0.05）。观察组总有效率为93.02%,明显高于对照组的71.13%,两组比较差异有统计学意义（P〈0.05）。结论：中西医结合辨证施治老年痴呆,能起到标本标兼治,扶正祛邪之功效,临床疗效优于单一西药治疗。     

中西医结合治疗急性胰腺炎90例临床观察

目的 研究中西医结合治疗急性胰腺炎的临床疗效.方法 将90例急性胰腺炎患者按随机数字表法分为治疗组和对照组各45例,对照组采用予禁食,持续胃肠减压、营养支持,补液、纠正水、电解质紊乱、酸碱平衡失调,抑制胃酸分泌,抑制胰酶分泌等常规治疗,治疗组在对照组治疗基础上加用疏肝解郁、清热泻火、通里攻下中药内服.结果 治疗组45例患者痊愈19例,好转22例,无效4例,总有效率91.3%,对照组45例痊愈13例,好转25例,无效7例,总有效率84.6%,两组比较有显著性差异(P<0.05),两组主要观察指标恢复时间比较显示,治疗组腹痛、腹胀和上腹部压痛等症状的恢复时间明显少与对照组,二者差异有显著性(P<0.05),而发热、尿淀粉酶和白细胞指标则无显著性差异(P<0.05).结论 在西医常规治疗基础上加用中药治疗,充分发挥中西医结合治疗急性胰腺炎的优势,可提高临床疗效、缩短疗程,减少并发症,减少西药的副作用,值得进一步的推广.     

A survey on treatment of dry eye by traditional chinese medicine and integrative Chinese and Western medicine

Dryeyeisadisorderoftearfilmduetotear deficiencyorexcessivetearevaporationcausingdamagetotheinterpalpebralocularsurfaceandas sociatedwithsymptomsofoculardiscomfort(1).As itisnowoneofthemostcommonsuperficialdisor dersinophthalmologyintheworldaswellasinChi na,moreandmorepeopleattachimportancetothe study.ThetreatmentofdryeyebytraditionalChi nesemedicine(TCM)orintegrativeChineseandWesternmedicine(ICWM)isnowreviewedinthis paper.TREATMENTOFDRYEYEBYTCMANDICWMTHERAPY LocalTreatmentwi…     

颈动脉体瘤的中西医结合治疗

笔者通过对颈动脉体瘤病因、临床特征的总结及临床观察,探讨中西医结合治疗该病的有效途径。西医予行颈动脉体瘤切除术,术中注意保护颈内动脉、颅神经及其分支,避免周围组织损伤;中医围术期应用健脾益气、化痰通络散结合中药干预治疗,以降低术中风险,减少术后并发症,并对患者进行3个月的随访观察。本研究患者术后无偏瘫失语、面瘫、声音嘶哑等表现,随访3个月近期疗效良好。综上所述,中西医结合治疗颈动脉体瘤可以提高手术疗效,减少并发症发生。