Preclinical Evaluation Method for Total Knees Designed to Restore Normal Knee Mechanics

The objective was to develop a simple, rapid, and low-cost method for evaluating proposed new total knee arthroplasty (TKA) models and then to evaluate 3 different TKA models with different kinematic characteristics. A “desktop” knee testing rig was used to apply forces and moments over a full flexion range, representing a spectrum of positions and activities; and the positions of the femur on the tibia were measured. The average neutral path of motion (for compressive force only) and the laxities about the neutral path (for superimposed shear and torque) were determined from 8 knee specimens to be used as a benchmark for the TKA evaluations. A typical posterior-stabilized TKA did not display the normal external femoral rotation with flexion and also showed abnormal anterior sliding on the medial side. A medial-pivot type of guided-motion design showed medial stability comparable to anatomical but still did not produce external femoral rotation and posterior lateral displacement with flexion. The addition of a central cam-post produced the rotation and displacement but only after 75° of flexion. It was concluded that the test method satisfied the objective and could be used as a design tool for evaluating new and existing designs, as well as for formulating a TKA with anatomical characteristics.     

Analysis of weight-bearing kinematics of posterior-stabilized total knee arthroplasty with novel helical post-cam design

We developed a new posterior-stabilized total knee arthroplasty (TKA) with a unique post-cam design that induces and accommodates internal tibial rotation with deep knee flexion. To validate the design concept of this system, we conducted an image analysis study employing a computer-aided diagnosis system for 24 TKA-implanted knees. In the analysis, the tibiofemoral relationship in the following 3 postures was evaluated: standing at extension, forward lunge, and kneeling with maximum knee flexion. The results of the image analysis showed achievement of consistent internal rotation of the tibia in deep flexion with a broad contact area at the post-cam interface as intended by the original design concept of this TKA system.     

Influence of Total Knee Arthroplasty on Patellar Kinematics and Patellofemoral Pressure

Background

Patellofemoral complications are one of the main problems after total knee arthroplasty (TKA). The design of the TKA component may affect the patellar biomechanics, which may be associated with this postoperative complication. The purpose of this study was to assess the influence of TKA and prosthesis designs on the patellar kinematics and patellofemoral pressure.

Knee kinematics of high-flexion activities of daily living performed by male Muslims in the Middle East

Full flexion is critical for total knee arthroplasty (TKA) patients in the Middle East, where daily activities require a high range of motion in the lower limb. This study aimed to increase understanding of the knee kinematics of normal Muslim subjects during high-flexion activities of daily living, such as kneeling, Muslim prayer, sitting cross-legged, and squatting. The early postoperative kinematics for a select group of Muslim, high-flexion TKA patients are also reported. Mean curves were compared between the normal group and the TKA group. During kneeling, the average maximum flexion was 141.6° for the normal group and 140.2° for the TKA group. The normal group's maximum and minimum knee angles (flexion, abduction, external rotation) were reported and, with the exception of maximum extension, were not significantly different from the TKA group, despite short postoperative times.     

In Vivo Knee Kinematics in Patients With Bilateral Total Knee Arthroplasty of 2 Designs

Many younger and highly active patients desire to achieve high flexion after total knee arthroplasty. This study's purpose was to determine if a contemporary total knee arthroplasty design improved functional knee flexion compared with a traditional total knee arthroplasty in patients living a Western lifestyle. Ten patients with bilateral total knee arthroplasty of 2 types were studied during weight-bearing lunge, kneeling, and stair activities using fluoroscopic imaging. There were no differences in maximum knee flexion during lunging or kneeling. Statistically significant differences in tibial rotation and condylar translation were observed during the 3 activities. Although several joint kinematic differences were observed, no important functional differences were observed in clinically excellent, high performing subjects with bilateral total knee arthroplasty of 2 types.     

Design features of total knees for achieving normal knee motion characteristics

The goal of the study was to achieve a normal neutral anatomical path of motion with a total knee arthroplasty (TKA) using specific motion-guiding design features. Two reference TKA models were used, consisting of a partially conforming double-dished geometry and the same with a central cam-post for femoral rollback. Four experimental TKA models included features to produce femoral rollback with and without guidance for tibial rotation, and a feature to prevent paradoxical anterior femoral sliding. The femur was loaded down the tibial axis, and the femoral-tibial positions were recorded at a sequence of flexion angles. Subsequently, the positions were recorded with an anterior shear force superimposed. Software was used to reconstruct the paths of the transverse femoral axis on the tibia, during a full flexion range. The reference knees did not reproduce a normal neutral path of motion. However, this was achieved with an experimental design incorporating all of the motion-guiding features.     

Lower Limb Biomechanics in Individuals With Knee Osteoarthritis Before and After Total Knee Arthroplasty Surgery

We investigated the biomechanical changes that occur in the lower limb following total knee arthroplasty (TKA). Lower limb joint kinematics and kinetics were evaluated in 32 patients before and 12 months following TKA and 28 age-matched controls. Analysis of variance with Bonferroni-adjusted post-hoc tests showed no significant changes in knee joint kinematics and kinetics following TKA despite significant improvements in pain and function. Significant increases in peak ankle plantarflexion and dorsiflexion moments and ankle power generation were observed which may be a compensatory response to impaired knee function to allow sufficient power generation for propulsion. Differences in knee gait parameters may arise as a result of the presence of osteoarthritis and mechanical changes associated with TKA as well as retention of the pre-surgery gait pattern.     

Fluoroscopic and Computed Tomographic Analysis of Knee Kinematics During Very Deep Flexion After Total Knee Arthroplasty

We examined the relative motion of femoral and tibial total knee arthroplasty components and the difference between 2 different tibial inserts (9 flat types and 7 dish types) in patients sitting in very deep flexion. X-ray, fluoroscopic examination, and computed tomography were used to analyze liftoff, and rotation. During seiza-style sitting, one knee (11%) with the flat insert lifted off on the medial side and 5 knees (71%) with the dish-type insert showed liftoff. The tibial internal rotation angles were 17.2° ± 4.1° (flat type) and 11.7° ± 3.1° (dish type) (P < .05). The flat type showed less liftoff at the medial side and more internal rotation. For very deep flexion, components that tolerate larger rotational freedom are favorable.     

Analysis of the kinematics of total knee prostheses with a medial pivot design

Analysis of the kinematics of the FINE Total Knee System (Nakashima Medical, Okayama, Japan) revealed that the medial condyle is fixed and the lateral condyle shows lateral posterior movement and tibial internal rotation. Analysis of the kinematics of the ADVANCE Total Knee System (Wright Medical Technology, Arlington, Tenn) revealed that the medial condyle is fixed and the lateral condyle shows anterior movement in the early stage, changing thereafter to posterior movement. With regard to rotation, initial external rotation subsequently changes to internal rotation. Analysis of the kinematics of the ADVANTIM Total Knee System (Wright Medical Technology) revealed that the bicondyle shows posterior movement, subsequently changing to anterior and posterior movements. Thus, unlike the FINE or ADVANCE Total Knee Systems, the ADVANTIM Total Knee System shows internal rotation.     

In Vivo Kinematic Comparison Between Mobile-Bearing and Fixed-Bearing Total Knee Arthroplasty During Step-Up Activity

Mobile-bearing total knee arthroplasty (TKA) expects high conformity and low contact stress. It is designed to correct the rotational mismatch between femoral and tibial components. We examined the difference in weight-bearing knee kinematics in patients with mobile-bearing and fixed-bearing TKA performing step-up activities. We randomly assigned 40 knees (37 patients) to mobile-bearing TKA (n = 20) or fixed-bearing TKA (n = 20). Using fluoroscopic imaging we evaluated knee kinematics during step-up activity one year after surgery. The total extent of rotation was not different for the two TKAs. Due to the axial rotation of the polyethylene insert, patients with mobile-bearing TKA had a wider range of absolute axial rotation. The position of the medial and the lateral condyles was significantly more posterior in the fixed-bearing TKA. There were only minor kinematic differences between the two TKAs. The polyethylene insert in the mobile-bearing TKA moved as designed especially with respect to the self-alignment feature.     

Neutral mechanical alignment: Stickin’ with the one that brung ya—Opposes

Total knee arthroplasty is a safe and reproducible procedure for the treatment of arthritis. Despite increased use and modern techniques, there remains up to a 20% rate of patient dissatisfaction for reasons unexplained in the literature. One hypothesis is that universally targeting a neutral, mechanical alignment rather than taking a more individualized approach to patient alignment may contribute to patient dissatisfaction. Constitutional varus and kinematic alignment techniques aim to match patient anatomy more closely in total knee arthroplasty and are discussed in detail in this review.     

The knee adduction moment during gait is associated with the adduction angle measured during computer-assisted total knee arthroplasty

Computer-assisted surgery can be used to measure 3-dimensional knee function during arthroplasty surgery; however, it is unknown if the movement of the knee measured during surgery is related to the in vitro, dynamic state of the knee joint, specifically the knee adduction moment during gait, which has been related to implant migration. The purpose of this study was to determine if the preoperative adduction moment is correlated with the knee abduction/adduction angle measured intraoperatively. A statistically significant correlation was found between the mean (r(2) = 0.59; P = .001) and peak (r(2) = 0.53; P = .003) preoperative knee adduction moment and the mean abduction/adduction angle measured intraoperatively. The association found in this study suggests the potential for incorporating functional information that relates to surgical outcome into surgical decision making using computer-assisted surgery.     

In Vivo Comparison of Knee Kinematics Before and After High-Flexion Posterior Cruciate-Retaining Total Knee Arthroplasty

The objectives of this study were to compare preoperative and postoperative knee kinematics for subjects implanted with flexion-enhanced posterior cruciate-retaining total knee arthroplasty during deep flexion and to examine flexion performance of the prosthesis design. Three-dimensional kinematics was analyzed by fluoroscopic examinations of subjects using a single-plane model-image registration technique. Preoperatively, knee kinematics demonstrated small posterior femoral translation and limited axial rotation. These motions differed significantly from patterns previously reported for normal knees. Postoperatively, flexion performance was maintained, averaging 130°, and kinematic patterns were similar to preoperative patterns. Although total knee arthroplasty can reduce pain and maintain functional performance, it appears that the characteristics of varus arthritic knee mechanics persist after arthroplasty.     

Can Post-Cam Function Be Replaced by Addition of a Third Condyle in PS TKA?

The purpose of the study was to analyze the effectiveness of an additional ball and socket articulation in implanted knees and whether it can replicate post-cam function. Fifteen knees implanted with a cruciate substituting (CS) polyethylene without a post and ten knees implanted with a posterior stabilized (PS) polyethylene with a post were analyzed using 3D model fitting approach. Two types of designs showed similar posterior translation and similar axial rotation. Most of the contact points at the ball and socket joint stayed within the socket height for the PS group. This study indicates that the ball and socket joint is able to function as a replacement of the post-cam mechanism, which might serve as a new way to achieve posterior stability.     

Kinematic Differences Between Gender Specific and Traditional Knee Implants

In the ongoing debate about gender-specific (GS) vs. traditional knee implants, there is limited information about patella-specific outcomes. GS femoral component features should provide better patellar tracking, but techniques have not existed previously to test this accurately. Using novel computed tomography and radiography imaging protocols, 15 GS knees were compared to 10 traditional knees, for the 6 degrees of freedom of the patellofemoral and tibiofemoral joints throughout the range of motion, plus other geometric measures and quality of life (QOL). Significant differences were found for patellar medial/lateral shift, where the patella was shifted more laterally for the GS femoral component. Neither group demonstrated patellar maltracking. There were no other significant differences in this well-functioning group.     

In vivo knee kinematics during stair and deep flexion activities in patients with bicruciate substituting total knee arthroplasty

Orthopedic surgeons and their patients continue to seek better functional outcomes after total knee arthroplasty. The bicruciate substituting (BCS) total knee arthroplasty design has been introduced to achieve more natural knee mechanics. The purpose of this study was to characterize kinematics in knees with BCS arthroplasty during deep flexion and stair activities using fluoroscopy and model-image registration. In 20 patients with 25 BCS knees, we observed average implant flexion of 128° during kneeling and consistent posterior condylar translations with knee flexion. Tibial rotations were qualitatively similar to those observed in the arthritic natural knee. Knee kinematics with BCS arthroplasty were qualitatively more similar to arthritic natural knees than knees with either posterior cruciate-retaining or posterior-stabilized arthroplasty.     

Role of Anatomical Patella Replacement on Anterior Knee Pain

Background

Anterior knee pain (AKP) remains a complex issue affecting patient satisfaction after total knee arthroplasty. Several radiographic parameters have been shown to be causative factors with various designs. The aim of this study is to evaluate the known radiographic parameters of AKP and clinical outcomes (ie, AKP) in the setting of a modern prosthesis with an anatomic patella button.