Preclinical Evaluation Method for Total Knees Designed to Restore Normal Knee Mechanics

The objective was to develop a simple, rapid, and low-cost method for evaluating proposed new total knee arthroplasty (TKA) models and then to evaluate 3 different TKA models with different kinematic characteristics. A “desktop” knee testing rig was used to apply forces and moments over a full flexion range, representing a spectrum of positions and activities; and the positions of the femur on the tibia were measured. The average neutral path of motion (for compressive force only) and the laxities about the neutral path (for superimposed shear and torque) were determined from 8 knee specimens to be used as a benchmark for the TKA evaluations. A typical posterior-stabilized TKA did not display the normal external femoral rotation with flexion and also showed abnormal anterior sliding on the medial side. A medial-pivot type of guided-motion design showed medial stability comparable to anatomical but still did not produce external femoral rotation and posterior lateral displacement with flexion. The addition of a central cam-post produced the rotation and displacement but only after 75° of flexion. It was concluded that the test method satisfied the objective and could be used as a design tool for evaluating new and existing designs, as well as for formulating a TKA with anatomical characteristics.     

Intraoperative passive kinematics of osteoarthritic knees before and after total knee arthroplasty.

Total knee arthroplasty is a successful procedure to treat pain and functional disability due to osteoarthritis. However, precisely how a total knee arthroplasty changes the kinematics of an osteoarthritic knee is unknown. We used a surgical navigation system to measure normal passive kinematics from 7 embalmed cadaver lower extremities and in vivo intraoperative passive kinematics on 17 patients undergoing primary total knee arthroplasty to address two questions: How do the kinematics of knees with advanced osteoarthritis differ from normal knees?; and, Does posterior substituting total knee arthroplasty restore kinematics towards normal? Osteoarthritic knees displayed a decreased screw‐home motion and abnormal varus/valgus rotations between 10° and 90° of knee flexion when compared to normal knees. The anterior–posterior motion of the femur in osteoarthritic knees was not different than in normal knees. Following total knee arthroplasty, we found abnormal varus/valgus rotations in early flexion, a reduced screw‐home motion when compared to the osteoarthritic knees, and an abnormal anterior translation of the femur during the first 60° of flexion. Posterior substituting total knee arthroplasty does not appear to restore normal passive varus/valgus rotations or the screw motion and introduces an abnormal anterior translation of the femur during intraoperative evaluation. © 2006 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 24:1607–1614, 2006     

Design features of total knees for achieving normal knee motion characteristics

The goal of the study was to achieve a normal neutral anatomical path of motion with a total knee arthroplasty (TKA) using specific motion-guiding design features. Two reference TKA models were used, consisting of a partially conforming double-dished geometry and the same with a central cam-post for femoral rollback. Four experimental TKA models included features to produce femoral rollback with and without guidance for tibial rotation, and a feature to prevent paradoxical anterior femoral sliding. The femur was loaded down the tibial axis, and the femoral-tibial positions were recorded at a sequence of flexion angles. Subsequently, the positions were recorded with an anterior shear force superimposed. Software was used to reconstruct the paths of the transverse femoral axis on the tibia, during a full flexion range. The reference knees did not reproduce a normal neutral path of motion. However, this was achieved with an experimental design incorporating all of the motion-guiding features.     

In Vivo Knee Kinematics: How Important Are the Roles of Femoral Geometry and the Cruciate Ligaments?

BackgroundWhile posterior cruciate-retaining (PCR) implants are a more common total knee arthroplasty (TKA) design, newer bicruciate-retaining (BCR) TKAs are now being considered as an option for many patients, especially those that are younger. While PCR TKAs remove the ACL, the BCR TKA designs keep both cruciate ligaments intact, as it is believed that the resection of the ACL greatly affects the overall kinematic patterns of TKA designs. The objectives of this study are to assess the in vivo kinematics for subjects implanted with either a PCR or BCR TKA and to compare the in vivo kinematic patterns to the normal knee during flexion. These objectives were achieved with an emphasis on understanding the roles of the cruciate ligaments, as well as the role of changes in femoral geometry of nonimplanted anatomical femurs vs implanted subjects having a metal femoral component.MethodsTibiofemoral kinematics of 50 subjects having a PCR (40 subjects) or BCR (10 subjects) TKA were analyzed using fluoroscopy while performing a deep knee bend activity. The kinematics were compared to previously published normal knee data (10 subjects). Kinematics were determined during specific intervals of flexion where the ACL or PCL was most dominant.ResultsIn early flexion, subjects having a BCR TKA experienced more normal-like kinematic patterns, possibly attributed to the ACL. In mid-flexion, both TKA groups exhibited variable kinematic patterns, which could be due to the transitional cruciate ligament function period. In deeper flexion, both TKA functioned more similar to the normal knee, leading to the assumption that the PCL was properly balanced and functioning in the TKA groups. Interestingly, during late flexion (after 90°), the kinematic patterns for all three groups appeared to be statistically similar.ConclusionSubjects having a PCR TKA experienced greater weight-bearing flexion than the BCR TKA group. Subjects having a BCR TKA exhibited a more normal-like kinematic pattern in early and late flexion. The normal knee subjects achieved greater lateral condyle rollback and axial rotation compared to the TKA groups.     

In Vivo Kinematic Comparison of a Bicruciate Stabilized Total Knee Arthroplasty and the Normal Knee Using Fluoroscopy

Background

The bicruciate stabilized (BCS) total knee arthroplasty (TKA) features asymmetrical bearing geometry and dual substitution for the anterior cruciate ligament and posterior cruciate ligament (PCL). Previous TKA designs have not fully replicated normal knee motion, and they are characterized by lower magnitudes of overall rollback and axial rotation than the normal knee.

Computational evaluation of TKR stability using feedback‐controlled compressive loading

Pre‐clinical assessment of stability in total knee replacement is crucial for developing preferred implant performance. Current total knee replacement patients often experience joint instability that the human body addresses with compensatory strategies. Specifically, an increased quadriceps‐hamstrings co‐contraction serves to increase joint stability through an increased compressive force across the tibiofemoral joint. The aim of this study is to introduce a novel method to evaluate total knee replacement by determining the compressive loading required to achieve natural knee stability. Four current total knee replacement geometries in both their cruciate‐retaining and posterior‐stabilized forms are modeled in a finite‐element framework. The finite‐element model is initially validated experimentally using traditional knee laxity testing with a constant compressive load and anterior‐posterior displacement or internal‐external rotation. Model predictions of constraint are in reasonable agreement with experimental results (average root mean square errors: 0.46 Nm, 62.5 N). The finite‐element model is subsequently interfaced with a feedback controller to vary the compressive force that the implant requires in order to match experimental natural knee internal‐external and anterior‐posterior stability at different flexion angles. Results show that the lower constraint total knee replacement designs require on average 66.7% more compressive load than the higher constraint designs to achieve natural knee constraint. As expected, total knee replacement stability and compressive load requirements to replicate natural kinematics vary with inclusion of tibiofemoral ligaments. The current study represents a novel approach to evaluate stability in existing total knee replacement geometries and to design implants that better restore natural knee mechanics. © 2018 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:1901–1909, 2018.

     

Condylar‐Stabilized TKR May Not Fully Compensate for PCL‐Deficiency: An In Vitro Cadaver Study

Increased‐congruency bearing options are widely available in numerous total knee replacement (TKR) systems, with the intended purpose of compensating for posterior‐cruciate ligament (PCL) deficiency. However, their ability to provide adequate stability in this setting has been debated. This in vitro joint simulator study measured changes in knee joint kinematics and stability during passive flexion–extension motions and simulated activities of daily living resulting from TKR with condylar‐stabilized (CS) TKR without a PCL versus cruciate‐retaining (CR) TKR. During passive flexion, the CS TKR resulted in a more posterior tibial positioning than both the intact joint and CR TKR (by 3.4 ± 1.0 mm and 4.8 ± 0.7 mm, respectively). With a posterior tibial force applied, the CS TKR tibia was again significantly more posterior than that of the intact joint and CR TKR (by 4.7 ± 1.3 mm and 5.6 ± 0.8 mm, respectively). Furthermore, there were significant differences in the anterior/posterior kinematics of both TKR with respect to intact knees during gait, and differences between the CS and CR TKR during stair ascent and descent. Overall, there appears to be a reduction in anterior–posterior stability of the PCL‐deficient CS TKR knee, suggesting that contemporary increased‐congruency bearing surface designs may not adequately compensate for the loss of the PCL. © 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 37:2172–2181, 2019     

Posterior cruciate ligament removal contributes to abnormal knee motion during posterior stabilized total knee arthroplasty

Abnormal anterior translation of the femur on the tibia has been observed in mid flexion (20–60°) following posterior stabilized total knee arthroplasty. The underlying biomechanical causes of this abnormal motion remain unknown. The purpose of this study was to isolate the effects of posterior cruciate ligament removal on knee motion after total knee arthroplasty. We posed two questions: Does removing the posterior cruciate ligament introduce abnormal anterior femoral translation? Does implanting a posterior stabilized prosthesis change the kinematics from the cruciate deficient case? Using a navigation system, we measured passive knee kinematics of ten male osteoarthritic patients during surgery after initial exposure, after removing the anterior cruciate ligament, after removing the posterior cruciate ligament, and after implanting the prosthesis. Passively flexing and extending the knee, we calculated anterior femoral translation and the flexion angle at which femoral rollback began. Removing the posterior cruciate ligament doubled anterior translation (from 5.1 ± 4.3 mm to 10.4 ± 5.1 mm) and increased the flexion angle at which femoral rollback began (from 31.2 ± 9.6° to 49.3 ± 7.3°). Implanting the prosthesis increased the amount of anterior translation (to 16.1 ± 4.4 mm), and did not change the flexion angle at which femoral rollback began. Abnormal anterior translation was observed in low and mid flexion (0–60°) after removing the posterior cruciate ligament, and normal motion was not restored by the posterior stabilized prosthesis. © 2008 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 26:1494–1499, 2008     

Knee biomechanics after UKA and its relation to the ACL--a robotic investigation.

Unicompartmental knee arthroplasty (UKA) has regained popularity in recent years. However, limited data exist on how UKA affects knee biomechanics. The role of the anterior cruciate ligament (ACL) after fixed bearing UKA remains controversial. In this study, a robotic testing system was used to apply a quadriceps/hamstrings load to cadaveric knee specimens in the intact state, after medial UKA, and after transection of the ACL in UKA. The load was applied to the knee from full extension to 120 degrees of flexion in 30 degrees increments. UKA generally did not affect anterior-posterior (AP) femoral position, but did cause external tibial rotation and variations in varus-valgus rotation compared to the intact knee. ACL transection after UKA shifted the femur posteriorly compared to the intact and UKA knees and increased internal tibial rotation compared to the UKA knee at low flexion. The AP motion of the articular contact position in the implant was increased after ACL transection. These data might help explain the mechanism of tibial component loosening and provide insight into further investigations of polyethylene wear in UKA. Based on the kinematic data, the ACL should be functional to provide patients the greatest opportunity for long-term success after medial UKA.     

Flexion–extension gap in cruciate‐retaining versus posterior‐stabilized total knee arthroplasty: A cadaveric study

We re‐examined experimental model results using half‐body specimens with intact extensor mechanisms and navigation to evaluate cruciate‐retaining (CR) and posterior stabilized (PS) total knee arthroplasty (TKA) component gaps through an entire range of motion. Six sequential testing regimens were conducted with the knee intact, with a CR TKA in place, and with a PS TKA in place, with and without 22 N traction in place at each stage. Each of 10 knees was taken through six full ranges of motion from 0° to 120° at every stage using a navigated knee system to record component gapping. No significant difference was found between loaded and unloaded component gaps, and no significant differences were found in component gapping between CR and PS TKAs throughout a full range of motion. Flexion–extension gap measurements were significantly different from previously published data (at 90° flexion). No difference was found in kinematics when comparing CR and PS TKA component designs. Our results suggest that intact extensor mechanisms may be required to perform proper kinematic studies of TKA. Our findings provide evidence that the extensor mechanism may play a major role in the flexion–extension gaps in cadaveric knees. © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 32:627–632, 2014.     

In Vivo Knee Kinematics for a Cruciate Sacrificing Total Knee Arthroplasty Having Both a Symmetrical Femoral and Tibial Component

BackgroundEarly total knee arthroplasty (TKA) designs were symmetrical, but lead to complications due to over-constraint leading to loosening and poor flexion. Next-generation TKAs have been designed to include asymmetry, pertaining to the trochlear groove, femoral condylar shapes, and/or the tibial component. More recently, an advanced posterior cruciate sacrificing (PCS) TKA was designed to include both a symmetrical femoral component with a patented V-shaped trochlear groove and a symmetrical tibial component with an ultracongruent insert, in an attempt to reduce inventory costs. Because previous PCS TKA designs produced variable results, the objective of this study is to determine and evaluate the in vivo kinematics for subjects implanted with this symmetrical TKA.MethodsTwenty-one subjects, implanted with symmetrical PCS fixed-bearing TKA, were asked to perform a weight-bearing deep knee bend (DKB) while under fluoroscopic surveillance. A 3-dimensional to 2-dimensional registration technique was used to determine each subject’s anteroposterior translation of lateral and medial femoral condyles as well as tibiofemoral axial rotation and their weight-bearing knee flexion.ResultsDuring the DKB, the average active maximum weight-bearing flexion was 111.7° ± 13.3°. On average, from full extension to maximum knee flexion, subjects experienced −2.5 ± 2.0 mm of posterior femoral rollback of the lateral condyle and 2.5 ± 2.2 mm of medial condyle motion in the anterior direction. This medial condyle motion was consistent for the majority of the subjects, with the lateral condyle exhibiting rollback from 0° to 60° of flexion and then experienced an average anterior motion of 0.3 mm from 60° to 90° of knee flexion. On average, the subjects in this study experienced 6.6°± 3.3° of axial rotation, with most of the rotation occurring in early flexion, averaging 4.9°.ConclusionAlthough subjects in this study were implanted with a symmetrical PCS TKA, they did experience femoral rollback of the lateral condyle and a normal-like pattern of axial rotation, although less in magnitude than the normal knee. The normal axial rotation pattern occurred because the lateral condyle rolled in the posterior direction, while the medial condyle moved in the anterior direction. Interestingly, the magnitude of posterior femoral rollback and axial rotation for subjects in this study was similar in magnitude reported in previous studies pertaining to asymmetrical TKA designs. It is proposed that more patients be analyzed having this TKA implanted by other surgeons.     

Comparison of the ACL and ACL graft forces before and after ACL reconstruction: an in-vitro robotic investigation

Background Long-term follow-up studies have indi-cated that there is an increased incidence of arthrosis following anterior cruciate ligament (ACL) reconstruc-tion, suggesting that the reconstruction may not repro-duce intact ACL biomechanics. We studied not only the magnitude but also the orientation of the ACL and ACL graft forces

Methods 10 knee specimens were tested on a robotic testing system with the ACL intact, deficient, and recon-structed (using a bone-patella tendon-bone graft). The magnitude and orientation of the ACL and ACL graft forces were determined under an anterior tibial load of 130 N at full extension, and 15, 30, 60, and 90° of flexion. Orientation was described using elevation angle (the angle formed with the tibial plateau in the sagit-tal plane) and deviation angle (the angle formed with respect to the anteroposterior direction in the transverse plane)

Results ACL reconstruction restored anterior tibial translation to within 2.6 mm of that of the intact knee under the 130-N anterior load. Average internal tibial rotation was reduced after ACL reconstruction at all flexion angles. The force vector of the ACL graft was significantly different from the ACL force vector. The average values of the elevation and deviation angles of the ACL graft forces were higher than that of the intact ACL at all flexion angles

Interpretation Contemporary single bundle ACL reconstruction restores anterior tibial translation under anterior tibial load with different forces (both magni-tude and orientation) in the graft compared to the intact ACL. Such graft function might alter knee kinematics in other degrees of freedom and could overly constrain the tibial rotation. An anatomic ACL reconstruction should reproduce the magnitude and orientation of the intact ACL force vector, so that the 6-degrees-of-freedom knee kinematics and joint reaction forces can be restored.     

Comparison of posterior-stabilized,cruciate-retaining,and medial-stabilized knee implant motion during gait

Accurate knowledge of knee joint motion is needed to evaluate the effects of implant design on functional performance and component wear. We conducted a randomized controlled trial to measure and compare 6-degree-of-freedom (6-DOF) kinematics and femoral condylar motion of posterior-stabilized (PS), cruciate-retaining (CR), and medial-stabilized (MS) knee implant designs for one cycle of walking. A mobile biplane X-ray imaging system was used to accurately measure 6-DOF tibiofemoral motion as patients implanted with PS (n = 23), CR (n = 25), or MS (n = 26) knees walked over ground at their self-selected speeds. Knee flexion angle did not differ significantly between the three designs. Relative movements of the femoral and tibial components were generally similar for PS and CR with significant differences observed only for anterior tibial drawer. Knee kinematic profiles measured for MS were appreciably different: external rotation and abduction of the tibia were increased while peak-to-peak anterior drawer was significantly reduced for MS compared with PS and CR. Anterior-posterior drawer and medial-lateral shift of the tibia were strongly coupled to internal-external rotation for MS, as was anterior-posterior translation of the contact center in the lateral compartment. MS exhibited the least amount of paradoxical anterior translation of the femur relative to the tibia during knee flexion. The joint center of rotation in the transverse plane was located in the lateral compartment for PS and CR and in the medial compartment for MS. Substantial differences were evident in 6-DOF knee kinematics between the healthy knee and all three prosthetic designs. Overall, knee kinematic profiles observed for MS resemble those of the healthy joint more closely than PS and CR.     

Influence of total knee replacement (TKR) design on screw-home movement: Comparison of five designs for total knee replacement prostheses

We evaluated the effect of surface geometry and retention of the posterior cruciate ligament (PCL) on screw-home movement in the knees of patients fitted with total knee replacement prostheses of five different designs (Miller/Galante [Zimmer, Warsaw, IN, USA], Mark II [Mizuho, Tokyo, Japan], Genesis PCL retaining, and cruciate substituting [Smith & Nephew/Richards, Memphis, TN, USA], and Yoshino/Shoji II [Biomet, Wiltshire, UK]). Three-dimensional motion was measured with a six-degree-of-freedom electrogoniometer (our original) during active flexion and extension of the knee. The Genesis-PCL retaining design, which has symmetric femoral and asymmetric tibial components, exhibited a pattern of screw-home movement closest to that in a normal control group (continuous external rotation between 30° flexion and extension). The implants with symmetric tibial components and the Genesis PCL-substituting design, with its asymmetric tibial articulating surface, did not replicate the screw-home movement. An asymmetric tibial articulating surface and retention of the PCL in total knee replacement may be important factors in allowing screw-home movement to occur.     

Kinematic Performance of Gradually Variable Radius Posterior-Stabilized Primary TKA During Various Activities: An In Vivo Study Using Fluoroscopy

BackgroundPosterior-stabilized total knee arthroplasty (TKA) with gradually variable radii (G-curve) femoral condylar geometry is now available. It is believed that a G-curve design would lead to more mid-flexion stability leading to reduced incidence of paradoxical anterior slide. The objective of this study was to assess the in vivo kinematics for subjects implanted with this type of TKA under various conditions of daily living.MethodsTibiofemoral kinematics of 35 patients having posterior-stabilized TKA with G-curve design were analyzed using fluoroscopy while performing three activities: weight-bearing deep knee bend, gait, and walking down a ramp. The subjects were assessed for range of motion, condylar translation, axial rotation, cam-spine engagement, and condylar lift-off.ResultsThe average weight-bearing flexion during deep knee bend was 111.4°. On average, the subjects exhibited 5.4 mm of posterior rollback of the lateral condyle and 2.0 mm of the medial condyle from full extension to maximum knee flexion. The femur consistently rotated externally with flexion, and the average axial rotation was 5.2°. Overall movement of the condyles during gait and ramp-down activity was small. No incidence of condylar lift-off was observed.ConclusionSubjects in this study experienced consistent magnitudes of posterior femoral rollback and external rotation of the femur with weight-bearing flexion. The variation is similar to that previously reported for normal knee where the lateral condyle moves consistently posterior compared to the medial condyle. Subjects experienced low overall mid-flexion paradoxical anterior sliding and no incidence of condylar lift-off leading to mid-flexion stability.     

Fixed‐bearing medial unicompartmental knee arthroplasty restores neither the medial pivoting behavior nor the ligament forces of the intact knee in passive flexion

Medial unicompartmental knee arthroplasty (UKA) is an accepted treatment for isolated medial osteoarthritis. However, using an improper thickness for the tibial component may contribute to early failure of the prosthesis or disease progression in the unreplaced lateral compartment. Little is known of the effect of insert thickness on both knee kinematics and ligament forces. Therefore, a computational model of the tibiofemoral joint was used to determine how non‐conforming, fixed bearing medial UKA affects tibiofemoral kinematics, and tension in the medial collateral ligament (MCL) and the anterior cruciate ligament (ACL) during passive knee flexion. Fixed bearing medial UKA could not maintain the medial pivoting that occurred in the intact knee from 0° to 30° of passive flexion. Abnormal anterior–posterior (AP) translations of the femoral condyles relative to the tibia delayed coupled internal tibial rotation, which occurred in the intact knee from 0° to 30° of flexion, but occurred from 30° to 90° of flexion following UKA. Increasing or decreasing tibial insert thickness following medial UKA also failed to restore the medial pivoting behavior of the intact knee despite modulating MCL and ACL forces. Reduced AP constraint in non‐conforming medial UKA relative to the intact knee leads to abnormal condylar translations regardless of insert thickness even with intact cruciate and collateral ligaments. This finding suggests that the conformity of the medial compartment as driven by the medial meniscus and articular morphology plays an important role in controlling AP condylar translations in the intact tibiofemoral joint during passive flexion. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:1868–1875, 2018.

     

Influence of Component Geometry on Patellar Mechanics in Posterior-Stabilized Rotating Platform Total Knee Arthroplasty

Background

Patellofemoral complications may cause pain and discomfort, sometimes leading to revision surgery for total knee arthroplasty patients, and patellar implant design has an impact on function of the reconstructed knee. The purpose of this in vivo biomechanics study was to understand the kinematic, functional, strength, and patient-reported outcome data of patients with anatomic and dome patellar implants.

Kinematics of medial osteoarthritic knees before and after posterior cruciate ligament retaining total knee arthroplasty

Total knee arthroplasty (TKA) is a widely accepted surgical procedure for the treatment of patients with end‐stage osteoarthritis (OA). However, the function of the knee is not always fully recovered after TKA. We used a dual fluoroscopic imaging system to evaluate the in vivo kinematics of the knee with medial compartment OA before and after a posterior cruciate ligament‐retaining TKA (PCR‐TKA) during weight‐bearing knee flexion, and compared the results to those of normal knees. The OA knees displayed similar internal/external tibial rotation to normal knees. However, the OA knees had less overall posterior femoral translation relative to the tibia between 0° and 105° flexion and more varus knee rotation between 0° and 45° flexion, than in the normal knees. Additionally, in the OA knees the femur was located more medially than in the normal knees, particularly between 30° and 60° flexion. After PCR‐TKA, the knee kinematics were not restored to normal. The overall internal tibial rotation and posterior femoral translation between 0° and 105° knee flexion were dramatically reduced. Additionally, PCR‐TKA introduced an abnormal anterior femoral translation during early knee flexion, and the femur was located lateral to the tibia throughout weight‐bearing flexion. The data help understand the biomechanical functions of the knee with medial compartment OA before and after contemporary PCR‐TKA. They may also be useful for improvement of future prostheses designs and surgical techniques in treatment of knees with end‐stage OA. © 2010 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 29:40–46, 2011     

ACL forces and knee kinematics produced by axial tibial compression during a passive flexion–extension cycle

Application of axial tibial force to the knee at a fixed flexion angle has been shown to generate ACL force. However, direct measurements of ACL force under an applied axial tibial force have not been reported during a passive flexion–extension cycle. We hypothesized that ACL forces and knee kinematics during knee extension would be significantly different than those during knee flexion, and that ACL removal would significantly increase all kinematic measurements. A 500 N axial tibial force was applied to intact knees during knee flexion–extension between 0° and 50°. Contact force on the sloping lateral tibial plateau produced a coupled internal + valgus rotation of the tibia, anterior tibial displacement, and elevated ACL forces. ACL forces during knee extension were significantly greater than those during knee flexion between 5° and 50°. During knee extension, ACL removal significantly increased anterior tibial displacement between 0° and 50°, valgus rotation between 5° and 50°, and internal tibial rotation between 5° and 15°. With the ACL removed, kinematic measurements during knee extension were significantly greater than those during knee flexion between 5° and 45°. The direction of knee flexion–extension movement is an important variable in determining ACL forces and knee kinematics produced by axial tibial force. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 32:89–95, 2014.     

Three‐dimensional patellar motion at the natural knee during passive flexion/extension. An in vitro study

Patellar maltracking may result in many patellofemoral joint (PFJ) disorders in the natural and replaced knee. The literature providing quantitative reference for normal PFJ kinematics according to which patellar maltracking could be identified is still limited. The aim of this study was to measure in vitro accurately all six‐degrees‐of‐freedom of patellar motion with respect to the femur and tibia on 20 normal specimens. A state‐of‐the‐art knee navigation system, suitably adapted for this study aim, was used. Anatomical reference frames were defined for the femur, tibia, and patella according to international recommendations. PFJ flexion, tilt, rotation, and translations were calculated in addition to standard tibiofemoral joint (TFJ) kinematics. All motion patterns were found to be generally repeatable intra‐/interspecimens. PFJ flexion was 62% of the corresponding TFJ flexion range; tilt and translations along femoral mediolateral and tibial proximodistal axes during TFJ flexion were found with medial, lateral, and distal trends and within 12°, 6 and 9 mm, respectively. No clear pattern for PFJ rotation was observed. These results concur with comparable reports from the literature and contribute to the controversial knowledge on normal PFJ kinematics. Their consistence provides fundamental information to understand orthopedic treatment of the knee and for possible relevant measurements intraoperatively. © 2009 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 27:1426–1431, 2009