Angiographic Observation of Immediate Effect of Electric Pulse Stimulation at Zhiyang Point on Coronary Artery

Angiographic Observation of Immediate Effect of Electric Pulse Stimulation at Zhiyang Point on Coronary Artery@颜红兵@柯元南@舒邦明@欧知宏@赵霞@赵桂茹     

Study on Therapeutic Mechanism of Xilei Powder(锡类散)for Peptic Ulcer

ＳｔｏｄｙｏｎＴｈｅｒａｐｅｕｔｉｃＭｅｃｈａｎｉｓｍｏｆＸｉｌｅｉＰｏｗｄｅｒ（锡类散）ｆｏｒＰｅｐｔｉｃＵｌｃｅｒＺＨＡＮＧＡｎ－ｔｉａｎ（张安田）；ＱＩＡＮＬｉｎ－ｘｕｅ（钱林学）；ＧＵＡＮＪｉｎｇ－ｍｉｎｇ（关景明）；ＤＵＹａ－ｊｕ（杜亚菊）...     

Effect of Stimulation of Shenshu Point on the Aging Process of Genital System in Aged Female Rats and the Role of Monoamine Neurotransmitters

In this experiment, among some aged female rats aged over 18 months, and young female rats aged 3 months whose central noradrenergic nerve endings were injured by ventricular injection of 6-hydroxy-dopamine (6-OHDA), it was observed that catgut embedding at bilateral Shenshu (UB 23) points could obviously shorten sexual cycles, increase the frequency of sexual cycle, and slow down the aging process of the genital system in both the aged rats and in the rats with injured noradrenergic endings. After electroacupuncture (EA) at Shenshu (UB 23) points in the aged rats, the frequency of neuronal discharges in locus coeruleus (LC) was elevated and the activating rate of LC to neurons in the medial preoptic area (MPOA) of the hypothalamus was increased, while obvious effect on nucleus raphes magnus (NRM) and the effect of NRM on MPOA were not marked. It is suggested that stimulation of Shenshu (UB 23) point can strengthen the excitability of noradrenergic neurons, activate the ascending pathway of the brain stem--hypothalamus, raise the catecholamine (CA)/5-hydroxytryptamine (5-HT) ratio in the hypothalamus of the aged rats, so as to delay the aging process of the genital system.     

Moluo Yangping Granule (摩罗疡平冲剂) in Treating 64 Peptic Ulcer Patients

Ｐｅｐｔｉｃｕｌｃｅｒｉｓａｃｏｍｍｏｎａｎｄｆｒｅｑｕｅｎｔｌｙｅｎｃｏｕｎｔｅｒｅｄｄｉｓｅａｓｅ．Ｈ2 ｒｅｃｅｐｔｏｒｂｌｏｃｋｅｒａｎｄｓｅｖｅｒａｌｏｔｈｅｒｄｒｕｇｓｈａｖｅｂｅｅｎｕｓｅｄｉｎｔｒｅａｔｉｎｇｐｅｐｔｉｃｕｌｃｅｒ（ＰＵ）ｓｉｎｃｅｍａｎｙｙｅａｒｓａｇｏ,ｂｕｔｔｈｅｒｅｓｔｉｌｌｒｅｍａｉｎａｒａｔｈｅｒｌａｒｇｅｎｕｍｂｅｒｏｆｉｎ ｔｒａｃｔａｂｌｅｕｌｃｅｒａｎｄｒｅｃｕｒｒｅｎｔｕｌｃｅｒ．ＲｅｃｅｎｔｌｙｔｈｅｄｉｓｃｏｖｅｒｙｏｆＨｅｌｉｃｏｂａｃｔ…     

Good Regulation of Acupunctore in Simple Obesity Patients with Stomach－Intestine Excessive Heat Type

ＧｏｏｄＲｅｇｕｌａｔｉｏｎｏｔＡｃｕｐｕｎｃｔｏｒｅｉｎＳｉｍｐｌｅＯｂｅｓｉｔｙＰａｔｉｅｎｔｓｗｉｔｈＳｔｏｍａｃｈ－ＩｎｔｅｓｔｉｎｅＥｘｃｅｓｓｉｖｅＨｅａｔＴｙｐｅＬｉｕＺｈｉ－ｃｈｅｎｇ（刘志诚）；ＷａｎｇＹｉ－ｚｈｅｎｇ（王沂争）；Ｈ...     

Effect of Blood-letting Puncture at Twelve Well-Points of Hand on Consciousness and Heart Rate in Patients with Apoplexy

To observe the effect of blood-letting puncture at Twelve Well-Points of Hand on consciousness and heart rate in patients with early apoplexy. Method: Under observation were patients with disturbance of consciousness within 3 days after the apoplectic seizure. The patients were divided into a large injury team, a moderate injury team and a mild injury team. Each team was again randomly divided into a puncture group and a control group, with routine treatment in both groups but bloodletting puncture only in the puncture group. Quantitative changes in consciousness, blood pressure and heart rate of the patients were observed. Result: Blood-letting puncture at Twelve Well-Points of Hand can improve the consciousness and raise the systolic pressure in patients of the mild injury team, and accelerate the heart rate in all the patients in the puncture group. Conclusion: Blood-letting puncture at Twelve Well-Points of Hand can imnrove the consciousness of natients with brain iniury in small area.     

Effect of Acupuncture on Immunomodulation in Patients with Malignant Tumors

ＥｆｆｅｃｔｏｆＡｃｕｐｕｎｃｔｕｒｅｏｎｌｍｍｕｎｏｍｏｄｕｌａｔｉｏｎｉｎＰａｔｉｅｎｔｓｗｉｌｈＭａｌｉｇｎａｎｔＴｕｍｏｒｓｗｕＢｉｎ（吴滨）；ＺＨＯＵＲｏｎｇ－ｘｉｎｓ（周荣兴）；ＣＨＥＮＭｉｎｓ－ｊｉｎ（陈名金）；ＺＨＡＮＧＹｏｎｇ－ｌｉ...     

Treatment of Peptic Ulcer with Xiao Jianzhong Tang——A Report of 80 Cases

With Xiao Jianzhong Tang (小建中汤), the author has successfully treated 80 cases of peptic ulcer. The therapeutic effects obtained were compared with that of the Western medicine. A report follows.     

Therapeutic Effect of Berberine on 60 Patients with Non－Insulin Dependent Diabetes Mellitus and Experimental Research

ＴｈｅｒａｐｅｕｔｉｃＥｆｆｅｃｔｏｆＢｅｒｂｅｒｉｎｅｏｎ６０ＰａｔｉｅｎｔｓｗｉｔｈＮｏｎ－ＩｎｓｕｌｉｎＤｅｐｅｎｄｅｎｔＤｉａｂｅｔｅｓＭｅｌｌｉｔｕｓａｎｄＥｘｐｅｒｉｍｅｎｔａｌＲｅｓｅａｒｃｈＮｉＹａｎ－ｘｉａ（倪艳霞）；ＬｉｕＡｎ－ｑ...     

The Effect of Electrical Stimulation of the Lateral Hypothalamic Area on the Pain Threshold of Rats

Effect of electrical stimulation of lateral hypothalamic area(LHA)on pain threshold of rats was studied by using tailflickresponse to radiant heat as the index of pain response and theinfluence of intraperitoneally injected naloxone on the analgesiceffect of LHA was observed.The result showed that pain thresholdof the animals raised 52.5% in average after LHA stimulation andthis analgesic action of LHA decreased significantly after injecionof naloxone.Quantitatively the analgesic effect of LHA was muchweaker than that of electroaccupuncture.The possible underlyingmechanisms were discussed.     

国产醋氨己酸锌治疗消化性溃疡疗效观察

目的 :观察醋氨己酸锌 (ZAC)治疗消化性溃疡的有效性及安全性。方法 :采用随机对照双盲双模拟方法治疗经胃镜检查证实的消化性溃疡 135例。ZAC治疗组 6 8例 ,其中十二指肠溃疡 (DU) 4 7例 ,胃溃疡 (GU) 2 1例 ;应用ZAC 0 .3g ,口服 ,3次 /d。西米替丁组 6 7例 ,其中DU 46例 ,GU 2 1例 ,应用西米替丁 0 .2g ,口服 ,3次 /d ,晚睡前服0 .4g。疗程 :DU 4周 ,GU 6周 ,结果 :溃疡愈合率ZAC组DU为 48% ,GU为 6 9% ;西米替丁组DU为 5 2 % ,GU为5 0 % ,2组比较差异无显著性 (P >0 .0 5 )。疼痛症状缓解率ZAC组DU为 70 % ,GU为 10 0 % ;西米替丁组DU为87% ,GU为 86 % (P >0 .0 5 ) ;不良反应率ZAC组为 16 % ,西米替丁组为 11% (P >0 .0 5 )。结论 :ZAC是一种有效的治疗消化性溃疡的药物。     

果胶铋三联与四联疗法治疗幽门螺杆菌阳性消化性溃疡的疗效比较

目的：比较果胶铋三联和四联疗法治疗幽门螺旋杆菌（no）阳性的消化性溃疡的疗效。方法：经电子胃镜和快速尿素酶方法确诊的Hp阳性胃溃疡和十二指肠溃疡共125例,按治疗方法分为2组,三联疗法组60例：果胶铋0．2g3次／日,克拉霉素0．5g27欠／日,甲硝唑0．4g,2次／日,1疗程为2周;四联疗法组：果胶铋、甲硝唑、克拉霉素用法用量同三联疗法,加用雷贝拉唑20mg,2次／日,1个疗程为1周。疗程结束4周后行电子胃镜及快速尿素酶试验复检。结果：125例均获随访,四联疗法组总有效率高于三联疗法组（P〈0．05）,症状缓解时间较三联疗法组短（P〈0．01）,不良反应发生率低于三联疗法组（P〈0．05）,Hp根除率与三联疗法差异无统计学意义（P〉0．05）。结论：含雷贝拉唑的四联疗法治疗Hp阳性的胃溃疡、十二指肠溃疡,其症状缓解时间、溃疡愈合,不良反应等方面优于三联疗法。     

舟山群岛渔民2772例消化性溃疡的流行病学分析

目的：了解舟山群岛渔民消化性溃疡发病（PU）特点。方法：对10年间舟山渔民经胃镜检查诊断为消化性溃疡的病例进行统计分析。结果：共检出2772例消化性溃疡患者。其中，十二指肠球部溃疡（DU）1846例，胃溃疡（GU）854例，复合性溃疡（CU）72例。DU患者的平均年龄36．2岁，GU患者的平均年龄为44．8岁，CU患者的平均年龄44．3岁，与当地普通男性居民相比，DU的发病年龄要提早5～10年，GU提早3～5年，而CU基本一致。DU和GU的四季检出率均以秋冬季节为高。DU在PU中所占比例为66．5％，结论：（1）渔民的PU检出率及幽门螺旋杆菌感染率较高。（2）病变好发部位以球部溃疡最多见，GU次之，CU最少。（3）PU与渔民在海上工作的年限、季节、生存环境和不良生活习惯密切相关。     

IL-1RN基因多态性与消化性溃疡发病相关性及机制分析

目的:探讨白细胞介素-1受体拮抗剂（IL-1RN）基因多态性与消化性溃疡的相关性。方法:选取2016年1月-2018年1月在我院治疗的消化性溃疡患者180例,其中十二指肠溃疡患者91例（十二指肠溃疡组）,胃溃疡患者89例（胃溃疡组）,同时选取健康志愿者270例作为对照组,检查IL-1RN基因多态性,采用快速尿素酶测定幽门螺旋杆菌感染情况。结果:十二指肠溃疡组IL-1RN基因型L/2+2/2比例和等位基因2比例分别为50.55%和29.67%,明显高于胃溃疡组和对照组（P＜0.05）;十二指肠溃疡组幽门螺旋杆菌阳性者IL-1RN基因型L/2+2/2比例和等位基因2比例分别为50.15%和29.38%,明显高于胃溃疡组和对照组（P＜0.05）;胃溃疡组幽门螺旋杆菌阴性者IL-1RN基因型L/2+2/2比例和等位基因2比例分别为62.50%和37.50%,明显高于对照组（P＜0.05）;十二指肠溃疡幽门螺旋杆菌阴性者等位基因2比例为31.82%,明显高于对照组（P＜0.05）;十二指肠溃疡组、胃溃疡组不同IL-1RN基因型患者治疗痊愈率比较差异无统计学意义（P＞0.05）。结论:IL-1RN基因多态性可能与十二指肠溃疡发病有一定的关系,值得进一步研究。     

功能性消化不良患者胃电图与胃排空关系研究

目的:探讨功能性消化不良患者的胃电图异常与胃排空的相关性.方法:使用PolygrafID四导胃电分析系统和不透X线标志物法测定51例功能性消化不良(FD)患者的胃电活动和餐后5 h的胃排空情况.结果:FD患者排空异常占31.4%,胃电异常占72.6%.胃电正常的患者与胃电异常的胃排空率差异无显著性.患者胃排空和胃电图异常时,胃电图节律紊乱,主频正常,部分患者合并餐后主功率不增加.轻度、中度及重度者胃排空率无明显差异;胃电异常率重度者较轻度、中度者明显增高(P＜0.05),轻度与中度症状之间、Hp阳性与Hp阴性的胃排空率差异均无显著性,Hp阳性的胃电异常率高于Hp阴性(P＜0.05).有或无活动性胃炎的胃电异常率及胃排空率无显著差异.结论:胃电异常在FD的发病中有一定意义;胃排空延缓与胃电异常无明显联系;重度症状患者和Hp阳性患者胃电异常率明显增高;胃炎有无活动性与胃电图及胃排空无明显相关性.     

消化性溃疡再出血82例发病诱因分析

目的: 分析消化性溃疡再出血的发病因素。方法: 统计患者的性别、年龄、溃疡大小、出血量、幽门螺杆菌(Hp)感染、腹痛、治疗情况、基础疾病、服非甾体类抗炎药(NSAID)史、营养状况、饮食习惯、劳动强度及夜间休息等临床资料,分析消化性溃疡再出血的发病因素。结果: 82例中十二指肠溃疡发生率为70.73%,胃溃疡为26.83%,<50岁青壮年为78.05%,无基本治疗87.80%,Hp阳性86.59%,夜间休息差78.05%,男性76.83%,女性23.17%,饮食习惯不良76.83%,劳累73.17%,营养不良56.10%。结论: 无基本治疗、Hp感染、年龄<50岁、夜间休息差、不良饮食习惯、劳累及营养不良是消化性溃疡再出血的主要诱发因素。     

腹腔镜下胃十二指肠穿孔修补术36例治疗体会

目的总结分析腹腔镜下胃十二指肠溃疡穿孔单纯修补术的临床效果及经验。方法对36例行腹腔镜下胃十二指肠溃疡穿孔修补术患者的临床资料进行回顾性分析。结果本组36例患者除1例中转开腹外,其余35例手术均获成功,无特殊并发症。结论腹腔镜下胃十二指肠溃疡穿孔修补术具有创伤小、痛苦轻、恢复快、并发症少、住院时间短等优点,是安全有效的手术方式,值得在基层医院推广。     

四联疗法治疗幽门螺杆菌阳性消化性溃疡的疗效观察

目的观察四联疗法治疗幽门螺杆菌阳性消化性溃疡的疗效。方法选择2011年1月～2012年1月本院收治幽门螺杆菌阳性消化性溃疡60例,应用四联疗法治疗,设为观察组;另选择同期应用三联疗法治疗的60例幽门螺杆菌阳性消化性溃疡患者,设为对照组,比较两组治疗4周后的疗效及幽门螺杆菌的根除率。结果治疗4周后,观察组总有效率93.3%,高于对照组总有效率70.00%,观察组的幽门螺杆菌根除率达90.0%,高于对照组幽门螺杆菌根除率78.00%（P〈0.05）。结论以PPI为主的四联疗法治疗消化性溃疡Hp根除率高、疗效确切,不良反应小、患者耐受性好,值得推广和应用。     

消化性溃疡中医药治疗概述

根据研究相关文献,从辨证论治、辨病施治、针灸治疗等各个方面对消化性溃疡中医药治疗进行概述,目的在于指导临床的治疗。     

十二指肠溃疡患者胃上皮化生与幽门螺杆菌关系的研究

目的 研究十二指肠溃疡患者胃上皮化生和幽门螺杆菌的关系。方法 收集门诊行上消化道胃镜检查确诊的十二指肠溃疡患者70例，另选胃和十二指肠黏膜正常患者55例为对照组。用快速尿素酶法和幽门活组织检查半定量法检测幽门螺杆菌(Hp)，苏木素一伊红染色和Schiff过碘酸染色半定量法检测十二指肠球部胃上皮化生。结果 十二指肠溃疡患者与对照组相比，十二指肠球部胃上皮化生检出率高；十二指肠球部胃上皮化生检出率和评分与胃幽门部Hp的检出率和评分无相关关系。结论 Hp不是十二指肠黏膜胃上皮化生的决定因素，也不是十二指肠黏膜胃上皮化生范围得以扩展的因素。十二指肠溃疡病本身的一些特点是十二指肠黏膜胃上皮化生的主要因素。