Central skeletal sarcoidosis mimicking metastatic disease

Sarcoidosis is a systemic disease that histologically typically shows non-caseating granulomas. The most common radiologic finding is hilar and mediastinal adenopathy. Patients with widely disseminated disease may show involvement of the peripheral appendicular skeleton in 1-13% of such cases. A primary skeletal presentation without other manifestations typical of the disease is rare. We present a case of sarcoidosis in a middle-aged Caucasian man in whom the disease presented with widespread lytic lesions in the axial skeleton and long bones, mimicking metastatic disease. There was no involvement of the peripheral skeleton, skin or lungs.     

Primary pulmonary amyloidosis with multiple nodules

A 61-year old asymptomatic woman had a five-year history of pulmonary nodular lesions on routine radiographs. She underwent open lung biopsy, which revealed nodular lesions in the lungs and thickened pleura. Histological examination showed amyloid deposits in the pulmonary parenchyma and adjacent pleura. Congo Red staining of the specimen demonstrated green birefringence under polarized light. This affinity for Congo Red dye remained after potassium permanganate treatment, suggesting primary amyloidosis. Multiple nodular amyloidosis of the lungs should be included in the differential diagnosis of multiple pulmonary nodules.     

Case report: tuberculous colitis mimicking Crohn's disease.

Although intestinal tuberculosis is rare in this country, increasing numbers of patients are now being seen, particularly in the immigrant population. We present the history of a lady who had acute diarrhoea and in whom the radiological and endoscopic findings looked very similar to those seen in Crohn's disease. The radiological presentation included widespread aphthous ulceration, a feature that has rarely been reported in tuberculous colitis.     

Report of tuberculous hepatitis presenting as metastatic disease

This is a case report of macronodular TB of the liver, without other known organ involvement, which presented with defects on RN scan and hypoechoic areas by ultrasound, suggesting metastatic disease. The demonstration on liver scan is quite rare and ultrasound visualization has not been reported. Although confirmation could not be obtained with AFB stain or positive culture, the clinical and liver scan response with a highly suggestive histologic picture are sufficient to make the diagnosis.     

Erdheim-chester disease mimicking multiple meningiomas syndrome

We describe a rare case of non-Langerhans histiocytosis, consistent with Erdheim-Chester disease (ECD), which presented with lesions resembling multiple meningiomas. The patient was initially evaluated for migraine headaches. Initial MR imaging demonstrated a parasellar mass and a second mass near the torcula considered to represent meningiomas. Within 1 year, he developed bilateral orbital lesions surrounding both optic nerves, which were also considered meningiomas. Biopsy of one orbital mass revealed a non-Langerhans histiocytosis. Subsequently, soft tissue masses, a pericardial effusion, and bone lesions consistent with ECD were identified.     

肺内多发小结节的CT诊断与鉴别诊断

目的：探讨肺内多发小结节的cT特征，提高cT诊断的准确性。方法：回顾性分析经病理或临床证实的53例肺内多发小结节患者的CT分布特征，其中血行性肺转移瘤15例，粟粒性肺结核8例，癌性淋巴管炎10例，矽肺3例，肺结核支气管播散10例，细支气管肺泡癌7例。结果：血行性肺转移瘤、粟粒性肺结核、细支气管肺泡癌小结节呈随机分布；癌性淋巴管炎、矽肺小结节沿淋巴管周围分布；肺结核支气管播散呈小叶中心分布。结论：CT对肺内多发小结节具有较大的诊断价值。     

Food residue granuloma mimicking metastatic disease on FDG-PET/CT

A 31-year-old woman presenting with acute abdomen underwent an emergency Hartmann’s procedure for fecal peritonitis due to perforated adenocarcinoma of the left colon. Shortly after a 7-month course of adjuvant chemotherapy, follow-up contrast-enhanced CT showed multiple peritoneal and hepatic nodules, showing focal intense and homogeneous FDG uptake on FDG-PET/CT, highly suspected for recurrence of disease. Excisional biopsy of the nodules revealed foreign body granulomas made up of alimentary materials surrounded by a fibrous wall. We report a unique case of a false-positive finding secondary to food residues mimicking metastatic disease on FDG-PET in a patient with colon cancer.     

Tendon abnormalities mimicking metastatic disease in patients with prostate cancer

We present plain x-ray examination, bone scintigraphy, computed tomography, and magnetic resonance imaging of 2 patients diagnosed with prostate cancer who complained of hip pain. Bone scintigraphy was suggestive for metastases. Further radiologic investigation revealed benign etiologies for the hip pain; calcific tendinitis of the vastus lateralis and tendonosis of the gluteus medius tendon were visualized.     

Sialadenitis mimicking metastatic thyroid carcinoma

In the post-thyroidectomy patient who has received I-131 ablation for thyroid carcinoma, focal uptake on repeat total body images is usually interpreted as being indicative of functioning thyroid metastases. The differential of focal I-131 activity in such a patient has been described. This report adds to the differential by presenting a case of benign sialadenitis that caused focal neck uptake a year after ablation therapy with I-131.     

Angiosarcoma of the pulmonary trunk mimicking pulmonary thromboembolic disease. A case report

We report on a 59-year-old male patient who suffered from dyspnea, cough and hemoptysis. Initial chest X-ray revealed a prominent right pulmonary artery (RPA) and MR imaging showed a “filling defect” within the main pulmonary trunk and RPA indicating pulmonary thromboembolic disease. Despite systemic anticoagulation, symptoms progressed. Follow-up CT showed an enlarging “filling defect” with additional extension into the left pulmonary artery as well as multiple intrapulmonary nodules. Lesion biopsy revealed a pulmonary artery angiosarcoma. Imaging findings are presented. Our case illustrates that pulmonary artery angiosarcoma should be included in the differential diagnosis of pulmonary thromboembolic disease in cases where a) symptoms do not respond to anticoagulation, b) no source of thrombi/emboli can be detected and c) pulmonary nodules/metastases develop on follow-up.